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DK135775B - Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. - Google Patents

Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Info

Publication number
DK135775B
DK135775B DK260473AA DK260473A DK135775B DK 135775 B DK135775 B DK 135775B DK 260473A A DK260473A A DK 260473AA DK 260473 A DK260473 A DK 260473A DK 135775 B DK135775 B DK 135775B
Authority
DK
Denmark
Prior art keywords
pregnanes
3alpha
5alpha
hydroxy
saturated
Prior art date
Application number
DK260473AA
Other languages
English (en)
Other versions
DK135775C (da
Inventor
Gordon Hanley Phillipps
Robin Lawrence
Leslie Stephenson
Barry Edward Ayres
Original Assignee
Glazo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glazo Lab Ltd filed Critical Glazo Lab Ltd
Publication of DK135775B publication Critical patent/DK135775B/da
Application granted granted Critical
Publication of DK135775C publication Critical patent/DK135775C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK260473AA 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. DK135775B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2248972A GB1436324A (en) 1972-05-12 1972-05-12 Anaesthetic 3alpha-hydroxy pregnanes

Publications (2)

Publication Number Publication Date
DK135775B true DK135775B (da) 1977-06-20
DK135775C DK135775C (da) 1977-11-21

Family

ID=10180241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260473AA DK135775B (da) 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Country Status (13)

Country Link
US (1) US3998829A (da)
JP (1) JPS4948652A (da)
AU (1) AU474687B2 (da)
BE (1) BE799433A (da)
CA (1) CA1014947A (da)
DE (1) DE2323950A1 (da)
DK (1) DK135775B (da)
FR (1) FR2184711B1 (da)
GB (1) GB1436324A (da)
IE (1) IE38863B1 (da)
LU (1) LU67585A1 (da)
NL (1) NL7306606A (da)
ZA (1) ZA733218B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613463A (en) * 1984-11-01 1986-09-23 The Upjohn Company Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5380840A (en) * 1985-09-12 1995-01-10 The Upjohn Company Triazinylpiperazinyl steroids
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
JPH072555Y2 (ja) * 1991-06-03 1995-01-25 日野自動車工業株式会社 車輛の前後方向兼用ウインチ
US6780853B1 (en) 1995-06-06 2004-08-24 Euro-Celtique S.A. Neuroactive steroids of the androstane and pregnane series
CA2223996A1 (en) * 1995-06-06 1996-12-19 Cocensys, Inc. Neuroactive steroids of the androstane and pregnane series
US6143737A (en) * 1995-06-23 2000-11-07 Georgetown University Progesterone analogs to reverse multidrug resistance
BR0010060A (pt) * 1999-04-29 2002-01-15 Purdue Pharma Ltd Esteróides 3<244>-hidroxi-3<225>-metoximetil-21-heterocìclo substituìdos com atividade anestésica
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
CA3152410A1 (en) 2011-10-14 2013-04-18 Sage Therapeutics, Inc. 3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
SI2986624T1 (sl) 2013-04-17 2020-10-30 Sage Therapeutics, Inc. 19-nor nevroaktivni steroidi za metode zdravljenja
PT3498725T (pt) 2013-04-17 2021-09-09 Sage Therapeutics Inc Esteroides c21-n-pirazolilo 19-nor c3,3-dissubstituídos para uso em terapia
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SI3021852T1 (sl) 2013-07-19 2021-07-30 Sage Therapeutics, Inc. Nevroaktivni steroidi, sestavki in uporabe le-teh
AU2014308621C1 (en) 2013-08-23 2022-01-06 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
KR102612943B1 (ko) * 2014-10-16 2023-12-13 세이지 테라퓨틱스, 인크. Cns 장애의 치료를 위한 조성물 및 방법
NZ769042A (en) 2014-10-16 2023-12-22 Sage Therapeutics Inc Compositions and methods for treating cns disorders
JP6893173B2 (ja) * 2014-11-27 2021-06-23 セージ セラピューティクス, インコーポレイテッド Cns障害を処置するための組成物および方法
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
ES2935476T3 (es) 2015-02-20 2023-03-07 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
EP3481844B1 (en) 2016-07-11 2024-04-17 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
DK3481845T3 (da) 2016-07-11 2023-11-27 Sage Therapeutics Inc C17, c20 og c21 substituerede neuroaktive steroider og deres anvendelsesmetoder
PE20230244A1 (es) 2019-05-31 2023-02-07 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1107662B (de) * 1959-07-04 1961-05-31 Merck Ag E Verfahren zur Herstellung von Mannichbasen von Steroiden bzw. von deren Saeureadditionssalzen
US3042691A (en) * 1960-05-11 1962-07-03 Pfizer & Co C 5alpha,21-dibromo-6beta-fluoro-21-methyl-pregnanes and process for making same
FR1764M (fr) * 1962-02-20 1963-04-08 Roussel Uclaf Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne ou viscérale.
US3201425A (en) * 1963-12-10 1965-08-17 American Cyanamid Co 20-alkoxy-delta20-21-carboxaldehydes of the pregnane series and method of preparing the same
GB1089945A (en) * 1965-09-23 1967-11-08 British Drug Houses Ltd Steroidal-6-spirocyclopropyl-4-en-3-ones
GB1317184A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Steroid-containing pharmaceutical preparations
DE1941226A1 (de) * 1969-08-13 1971-02-18 Degussa Basisch substituierte Ketosteroide
US3661940A (en) * 1970-04-13 1972-05-09 Sandoz Ag Derivatives of 21-methyl-19-norpregnanes
GB1377609A (en) * 1970-12-17 1974-12-18 Glaxo Lab Ltd 3alpha-hydroxy-5alpha-pregnane compounds
GB1416427A (en) * 1972-01-12 1975-12-03 Akzo Nv Alkylated pregnanes and process for obtaining same

Also Published As

Publication number Publication date
AU474687B2 (en) 1976-07-29
BE799433A (fr) 1973-11-12
DE2323950A1 (de) 1973-12-13
FR2184711B1 (da) 1977-01-07
AU5561673A (en) 1974-11-14
GB1436324A (en) 1976-05-19
US3998829A (en) 1976-12-21
CA1014947A (en) 1977-08-02
FR2184711A1 (da) 1973-12-28
DK135775C (da) 1977-11-21
JPS4948652A (da) 1974-05-11
NL7306606A (da) 1973-11-14
LU67585A1 (da) 1973-07-24
IE38863B1 (en) 1978-06-21
ZA733218B (en) 1974-05-29
IE38863L (en) 1973-11-12

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