DK135775B - Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. - Google Patents
Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.Info
- Publication number
- DK135775B DK135775B DK260473AA DK260473A DK135775B DK 135775 B DK135775 B DK 135775B DK 260473A A DK260473A A DK 260473AA DK 260473 A DK260473 A DK 260473A DK 135775 B DK135775 B DK 135775B
- Authority
- DK
- Denmark
- Prior art keywords
- pregnanes
- 3alpha
- 5alpha
- hydroxy
- saturated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2248972A GB1436324A (en) | 1972-05-12 | 1972-05-12 | Anaesthetic 3alpha-hydroxy pregnanes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK135775B true DK135775B (da) | 1977-06-20 |
| DK135775C DK135775C (da) | 1977-11-21 |
Family
ID=10180241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK260473AA DK135775B (da) | 1972-05-12 | 1973-05-11 | Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3998829A (da) |
| JP (1) | JPS4948652A (da) |
| AU (1) | AU474687B2 (da) |
| BE (1) | BE799433A (da) |
| CA (1) | CA1014947A (da) |
| DE (1) | DE2323950A1 (da) |
| DK (1) | DK135775B (da) |
| FR (1) | FR2184711B1 (da) |
| GB (1) | GB1436324A (da) |
| IE (1) | IE38863B1 (da) |
| LU (1) | LU67585A1 (da) |
| NL (1) | NL7306606A (da) |
| ZA (1) | ZA733218B (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613463A (en) * | 1984-11-01 | 1986-09-23 | The Upjohn Company | Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid |
| USRE35053E (en) * | 1985-09-12 | 1995-10-10 | The Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
| US5380840A (en) * | 1985-09-12 | 1995-01-10 | The Upjohn Company | Triazinylpiperazinyl steroids |
| US5099019A (en) * | 1985-09-12 | 1992-03-24 | Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| JPH072555Y2 (ja) * | 1991-06-03 | 1995-01-25 | 日野自動車工業株式会社 | 車輛の前後方向兼用ウインチ |
| US6780853B1 (en) | 1995-06-06 | 2004-08-24 | Euro-Celtique S.A. | Neuroactive steroids of the androstane and pregnane series |
| CA2223996A1 (en) * | 1995-06-06 | 1996-12-19 | Cocensys, Inc. | Neuroactive steroids of the androstane and pregnane series |
| US6143737A (en) * | 1995-06-23 | 2000-11-07 | Georgetown University | Progesterone analogs to reverse multidrug resistance |
| BR0010060A (pt) * | 1999-04-29 | 2002-01-15 | Purdue Pharma Ltd | Esteróides 3<244>-hidroxi-3<225>-metoximetil-21-heterocìclo substituìdos com atividade anestésica |
| US20050101581A1 (en) * | 2002-08-28 | 2005-05-12 | Reading Christopher L. | Therapeutic treatment methods 2 |
| CA3152410A1 (en) | 2011-10-14 | 2013-04-18 | Sage Therapeutics, Inc. | 3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| SI2986624T1 (sl) | 2013-04-17 | 2020-10-30 | Sage Therapeutics, Inc. | 19-nor nevroaktivni steroidi za metode zdravljenja |
| PT3498725T (pt) | 2013-04-17 | 2021-09-09 | Sage Therapeutics Inc | Esteroides c21-n-pirazolilo 19-nor c3,3-dissubstituídos para uso em terapia |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| SI3021852T1 (sl) | 2013-07-19 | 2021-07-30 | Sage Therapeutics, Inc. | Nevroaktivni steroidi, sestavki in uporabe le-teh |
| AU2014308621C1 (en) | 2013-08-23 | 2022-01-06 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| KR102612943B1 (ko) * | 2014-10-16 | 2023-12-13 | 세이지 테라퓨틱스, 인크. | Cns 장애의 치료를 위한 조성물 및 방법 |
| NZ769042A (en) | 2014-10-16 | 2023-12-22 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
| JP6893173B2 (ja) * | 2014-11-27 | 2021-06-23 | セージ セラピューティクス， インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| RS61530B1 (sr) | 2015-01-26 | 2021-04-29 | Sage Therapeutics Inc | Kompozicije i postupci za lečenje poremećaja cns |
| ES2935476T3 (es) | 2015-02-20 | 2023-03-07 | Sage Therapeutics Inc | Esteroides neuroactivos, composiciones y usos de los mismos |
| EP3481844B1 (en) | 2016-07-11 | 2024-04-17 | Sage Therapeutics, Inc. | C7, c12, and c16 substituted neuroactive steroids and their methods of use |
| DK3481845T3 (da) | 2016-07-11 | 2023-11-27 | Sage Therapeutics Inc | C17, c20 og c21 substituerede neuroaktive steroider og deres anvendelsesmetoder |
| PE20230244A1 (es) | 2019-05-31 | 2023-02-07 | Sage Therapeutics Inc | Esteroides neuroactivos y composiciones de estos |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1107662B (de) * | 1959-07-04 | 1961-05-31 | Merck Ag E | Verfahren zur Herstellung von Mannichbasen von Steroiden bzw. von deren Saeureadditionssalzen |
| US3042691A (en) * | 1960-05-11 | 1962-07-03 | Pfizer & Co C | 5alpha,21-dibromo-6beta-fluoro-21-methyl-pregnanes and process for making same |
| FR1764M (fr) * | 1962-02-20 | 1963-04-08 | Roussel Uclaf | Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne ou viscérale. |
| US3201425A (en) * | 1963-12-10 | 1965-08-17 | American Cyanamid Co | 20-alkoxy-delta20-21-carboxaldehydes of the pregnane series and method of preparing the same |
| GB1089945A (en) * | 1965-09-23 | 1967-11-08 | British Drug Houses Ltd | Steroidal-6-spirocyclopropyl-4-en-3-ones |
| GB1317184A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Steroid-containing pharmaceutical preparations |
| DE1941226A1 (de) * | 1969-08-13 | 1971-02-18 | Degussa | Basisch substituierte Ketosteroide |
| US3661940A (en) * | 1970-04-13 | 1972-05-09 | Sandoz Ag | Derivatives of 21-methyl-19-norpregnanes |
| GB1377609A (en) * | 1970-12-17 | 1974-12-18 | Glaxo Lab Ltd | 3alpha-hydroxy-5alpha-pregnane compounds |
| GB1416427A (en) * | 1972-01-12 | 1975-12-03 | Akzo Nv | Alkylated pregnanes and process for obtaining same |
-
1972
- 1972-05-12 GB GB2248972A patent/GB1436324A/en not_active Expired
-
1973
- 1973-05-08 US US05/358,381 patent/US3998829A/en not_active Expired - Lifetime
- 1973-05-11 FR FR7317079A patent/FR2184711B1/fr not_active Expired
- 1973-05-11 JP JP48052424A patent/JPS4948652A/ja active Pending
- 1973-05-11 BE BE131031A patent/BE799433A/xx unknown
- 1973-05-11 NL NL7306606A patent/NL7306606A/xx not_active Application Discontinuation
- 1973-05-11 LU LU67585A patent/LU67585A1/xx unknown
- 1973-05-11 AU AU55616/73A patent/AU474687B2/en not_active Expired
- 1973-05-11 CA CA171,026A patent/CA1014947A/en not_active Expired
- 1973-05-11 DK DK260473AA patent/DK135775B/da unknown
- 1973-05-11 IE IE00753/73A patent/IE38863B1/xx unknown
- 1973-05-11 ZA ZA733218A patent/ZA733218B/xx unknown
- 1973-05-11 DE DE2323950A patent/DE2323950A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU474687B2 (en) | 1976-07-29 |
| BE799433A (fr) | 1973-11-12 |
| DE2323950A1 (de) | 1973-12-13 |
| FR2184711B1 (da) | 1977-01-07 |
| AU5561673A (en) | 1974-11-14 |
| GB1436324A (en) | 1976-05-19 |
| US3998829A (en) | 1976-12-21 |
| CA1014947A (en) | 1977-08-02 |
| FR2184711A1 (da) | 1973-12-28 |
| DK135775C (da) | 1977-11-21 |
| JPS4948652A (da) | 1974-05-11 |
| NL7306606A (da) | 1973-11-14 |
| LU67585A1 (da) | 1973-07-24 |
| IE38863B1 (en) | 1978-06-21 |
| ZA733218B (en) | 1974-05-29 |
| IE38863L (en) | 1973-11-12 |
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