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DK132500B - Analogifremgangsmåde til fremstilling af 2beta, 16beta-diamino-5alfa-androstaner. - Google Patents

Analogifremgangsmåde til fremstilling af 2beta, 16beta-diamino-5alfa-androstaner.

Info

Publication number
DK132500B
DK132500B DK642473AA DK642473A DK132500B DK 132500 B DK132500 B DK 132500B DK 642473A A DK642473A A DK 642473AA DK 642473 A DK642473 A DK 642473A DK 132500 B DK132500 B DK 132500B
Authority
DK
Denmark
Prior art keywords
16beta
2beta
androstanes
5alpha
diamino
Prior art date
Application number
DK642473AA
Other languages
English (en)
Other versions
DK132500C (da
Inventor
C L Hewett
D S Savage
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK132500B publication Critical patent/DK132500B/da
Application granted granted Critical
Publication of DK132500C publication Critical patent/DK132500C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK642473*A 1972-11-29 1973-11-28 Analogifremgangsmade til fremstilling af 2beta,16beta-diamino-5alfa-androstaner DK132500C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5519172A GB1454749A (en) 1972-11-29 1972-11-29 2beta, 16beta-diamino-androstanes and their preparation

Publications (2)

Publication Number Publication Date
DK132500B true DK132500B (da) 1975-12-15
DK132500C DK132500C (da) 1976-05-17

Family

ID=10473231

Family Applications (1)

Application Number Title Priority Date Filing Date
DK642473*A DK132500C (da) 1972-11-29 1973-11-28 Analogifremgangsmade til fremstilling af 2beta,16beta-diamino-5alfa-androstaner

Country Status (18)

Country Link
US (1) US3872091A (da)
JP (1) JPS546557B2 (da)
BE (1) BE807988A (da)
CA (1) CA1018515A (da)
CH (1) CH605506A5 (da)
DE (1) DE2359076C2 (da)
DK (1) DK132500C (da)
ES (1) ES420922A1 (da)
FI (1) FI52349C (da)
FR (1) FR2207724B1 (da)
GB (1) GB1454749A (da)
HU (1) HU168724B (da)
IE (1) IE38513B1 (da)
NL (1) NL7316237A (da)
NO (1) NO139088C (da)
PH (1) PH12359A (da)
SE (1) SE395460B (da)
ZA (1) ZA738759B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172521B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh triamino-androstana i chetvertichnykh solejj
DE2962627D1 (en) * 1978-09-05 1982-06-09 Akzo Nv Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
IE53463B1 (en) * 1981-06-15 1988-11-23 Akzo Nv Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
GB8708886D0 (en) * 1987-04-14 1987-05-20 Akzo Nv 2beta-morpholino-androstane derivatives
CZ300694A3 (en) * 1993-12-02 1996-05-15 Akzo Nobel Nv Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
US5767112A (en) * 1994-10-21 1998-06-16 Poli Industria Chimica, S.P.A. Muscle relaxant pharmaceutical compositions
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
ATE417857T1 (de) * 2002-01-18 2009-01-15 Univ Minnesota Quaternäre terpensalze als biologisch aktive tenside
WO2012147090A1 (en) * 2011-04-26 2012-11-01 Neon Laboratories Ltd. Novel process for quaternization of (2p,3a,5a,16p,17p)-2,16-bispiperidino-3,17-diacetoxy-5-androstane

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
FR1468539A (fr) * 1965-02-19 1967-02-03 Organon Labor Ltd Nouveaux 2beta, 16beta-diamino-androstanes et procédé pour leur préparation

Also Published As

Publication number Publication date
JPS546557B2 (da) 1979-03-29
CH605506A5 (da) 1978-09-29
US3872091A (en) 1975-03-18
DE2359076C2 (de) 1983-12-08
BE807988A (fr) 1974-05-29
IE38513B1 (en) 1978-03-29
HU168724B (da) 1976-07-28
AU6286273A (en) 1975-05-29
ZA738759B (en) 1974-10-30
DK132500C (da) 1976-05-17
NO139088C (no) 1979-01-03
FI52349C (fi) 1977-08-10
FR2207724A1 (da) 1974-06-21
FR2207724B1 (da) 1977-09-02
JPS4993353A (da) 1974-09-05
ES420922A1 (es) 1976-04-01
IE38513L (en) 1974-05-20
FI52349B (da) 1977-05-02
DE2359076A1 (de) 1974-06-06
NO139088B (no) 1978-09-25
PH12359A (en) 1979-01-29
CA1018515A (en) 1977-10-04
SE395460B (sv) 1977-08-15
GB1454749A (en) 1976-11-03
NL7316237A (da) 1974-05-31

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Legal Events

Date Code Title Description
PBP Patent lapsed