DK133158C - Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere - Google Patents

Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere

Info

Publication number: DK133158C
Authority: DK; Denmark
Prior art keywords: acyloxyandrost; 17alfa; 17beta; oxo; production
Prior art date: 1972-07-19

Application number

DK397073A

Other languages

Danish (da)

English (en)

Other versions

DK133158B (da

Inventor

G H Phillipps

P J May

B M Bain

E A Woollett

Original Assignee

Glaxo Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-19

Filing date

1973-07-18

Publication date

1976-09-06

1973-07-18 Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd

1976-03-29 Publication of DK133158B publication Critical patent/DK133158B/da

1976-09-06 Application granted granted Critical

1976-09-06 Publication of DK133158C publication Critical patent/DK133158C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK397073A 1972-07-19 1973-07-18 Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere DK133158C (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB3383472A GB1438940A (en)	1972-07-19	1972-07-19	17beta-haloalkoxycarbonyl-17alpha-oxysteroids

Publications (2)

Publication Number	Publication Date
DK133158B DK133158B (da)	1976-03-29
DK133158C true DK133158C (da)	1976-09-06

Family

ID=10358062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK397073A DK133158C (da)	1972-07-19	1973-07-18	Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere

Country Status (18)

Country	Link
US (1)	US3856828A (de)
JP (1)	JPS5750800B2 (de)
AU (1)	AU473714B2 (de)
BE (1)	BE802481R (de)
CA (1)	CA1034565A (de)
CH (1)	CH619968A5 (de)
DE (1)	DE2336633A1 (de)
DK (1)	DK133158C (de)
ES (1)	ES417012A2 (de)
FR (1)	FR2192840B2 (de)
GB (1)	GB1438940A (de)
IE (1)	IE37925B1 (de)
IL (1)	IL42779A (de)
LU (1)	LU68039A1 (de)
NL (1)	NL7309992A (de)
PH (1)	PH14795A (de)
SE (1)	SE396079B (de)
ZA (1)	ZA734896B (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3943124A (en) *	1970-12-17	1976-03-09	Gordon Hanley Phillipps	Chemical compounds
US3989686A (en) *	1972-06-15	1976-11-02	Glaxo Laboratories Limited	Anaesthetic steroids of the androstane series and process for preparing same
GB1514476A (en) *	1974-08-30	1978-06-14	Glaxo Lab Ltd	Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
US4093721A (en) *	1974-08-30	1978-06-06	Glaxo Laboratories Limited	Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
DK118776A (da) *	1975-03-21	1976-09-22	Schering Ag	Pregnansyrederivater
CH628355A5 (de) *	1976-02-24	1982-02-26	Ciba Geigy Ag	Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
IT1114534B (it) *	1978-02-08	1986-01-27	Glaxo Group Ltd	Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo
US4187301A (en) *	1978-04-05	1980-02-05	Syntex (U.S.A.) Inc.	17 Beta-thiocarboxylic acid esters of 6 alpha, 6 beta-difluoro-3-oxoandrost-4-enes
US4188385A (en) *	1978-04-05	1980-02-12	Syntex (U.S.A.) Inc.	Thioetianic acid derivatives
US4252729A (en) *	1978-05-12	1981-02-24	Hoffmann-La Roche Inc.	Steroids and process for their manufacture
CH651307A5 (de) *	1980-02-15	1985-09-13	Glaxo Group Ltd	Androsta-carbothiosaeuren und verfahren zu ihrer herstellung.
SE449106B (sv) *	1980-07-10	1987-04-06	Otsuka Pharma Co Ltd	Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
US4710495A (en) *	1980-07-10	1987-12-01	Otsuka Pharmaceutical Co., Ltd.	Soft steroids having anti-inflammatory activity
US4996335A (en) *	1980-07-10	1991-02-26	Nicholas S. Bodor	Soft steroids having anti-inflammatory activity
CH649923A5 (de) *	1980-10-06	1985-06-28	Glaxo Group Ltd	Topisch verabreichbare pharmazeutische zusammensetzungen, enthaltend anti-inflammatorische steroide.
SE8306370D0 (sv) *	1983-11-18	1983-11-18	Draco Ab	Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
IL78144A0 (en) *	1985-04-04	1986-07-31	Draco Ab	Novel androstane-17beta-carboxylic acid esters
SE8501693D0 (sv) *	1985-04-04	1985-04-04	Draco Ab	Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
US4686214A (en) *	1985-10-30	1987-08-11	Alcon Laboratories, Inc.	Anti-inflammatory compounds for ophthalmic use
ATE90355T1 (de) *	1987-10-13	1993-06-15	Nicholas S Bodor	Weiche steroide mit anti-entzuendungswirkung.
US5981517A (en) *	1996-05-09	1999-11-09	Soft Drugs, Inc.	Androstene derivatives
GB0015876D0 (en) *	2000-06-28	2000-08-23	Novartis Ag	Organic compounds
US6858593B2 (en)	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6759398B2 (en)	2000-08-05	2004-07-06	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative
US6777400B2 (en) *	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6750210B2 (en)	2000-08-05	2004-06-15	Smithkline Beecham Corporation	Formulation containing novel anti-inflammatory androstane derivative
CO5310534A1 (es) *	2000-08-05	2003-08-29	Glaxo Group Ltd	Nuevos derivados de androstano anti-inflamatorios
US6777399B2 (en)	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) *	2000-08-05	2000-09-27	Glaxo Group Ltd	Novel compounds
US6858596B2 (en)	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivative
US6787532B2 (en)	2000-08-05	2004-09-07	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivatives
UA77656C2 (en)	2001-04-07	2007-01-15	Glaxo Group Ltd	S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
CA2445839A1 (en) *	2001-04-30	2002-11-07	Glaxo Group Limited	Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
GB0125259D0 (en) *	2001-10-20	2001-12-12	Glaxo Group Ltd	Novel compounds
AU2003202044A1 (en) *	2002-01-15	2003-09-09	Glaxo Group Limited	17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
WO2003062259A2 (en) *	2002-01-21	2003-07-31	Glaxo Group Limited	Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
GB0202216D0 (en) *	2002-01-31	2002-03-20	Glaxo Group Ltd	Novel compounds
US20050175545A1 (en) *	2002-02-04	2005-08-11	Keith Biggadike	Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) *	2002-02-05	2002-03-20	Glaxo Wellcome Mfg Pte Ltd	Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en)	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
GB0225287D0 (en) *	2002-10-30	2002-12-11	Glaxo Group Ltd	Novel compounds
EP1658083B1 (de)	2003-06-19	2007-08-08	BODOR, Nicholas S.	Verstärkung der aktivität und/oder wirkdauer von ausgewählten entzündungshemmenden steroiden
GB0316290D0 (en) *	2003-07-11	2003-08-13	Glaxo Group Ltd	Novel compounds
US20090124588A1 (en) *	2005-01-10	2009-05-14	Glaxo Group Limited	Androstane 17-Alpha-Carbonate for Use in the Treatment of Inflammatory and Allergic Conditions
ATE517908T1 (de) *	2005-01-10	2011-08-15	Glaxo Group Ltd	Androstan-17-alpha-carbonat-derivate zur verwendung bei der behandlung allergischer und entzündlicher zustände
GB0507165D0 (en) *	2005-04-08	2005-05-18	Glaxo Group Ltd	Novel crystalline pharmaceutical product
US20070245924A1 (en) *	2006-04-20	2007-10-25	Hofmann Michael A	Reduced abrasion of titanium dioxide pigments produced from the chloride process
GB0615108D0 (en) *	2006-07-28	2006-09-06	Glaxo Group Ltd	Novel formulations
CN106986804A (zh)	2010-10-27	2017-07-28	霍维奥恩联合有限公司	用于单卤代甲基基团转移的基于锍离子的亲电试剂、其制备和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3636010A (en) *	1968-12-23	1972-01-18	Ciba Geigy Corp	Esters of steroid-17-carboxylic acids
GB1384372A (en) *	1971-01-20	1975-02-19	Glaxo Lab Ltd	Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids

1972
- 1972-07-19 GB GB3383472A patent/GB1438940A/en not_active Expired
1973
- 1973-07-16 US US00379471A patent/US3856828A/en not_active Expired - Lifetime
- 1973-07-17 ES ES417012A patent/ES417012A2/es not_active Expired
- 1973-07-18 CA CA176,804A patent/CA1034565A/en not_active Expired
- 1973-07-18 IL IL42779A patent/IL42779A/en unknown
- 1973-07-18 DK DK397073A patent/DK133158C/da not_active IP Right Cessation
- 1973-07-18 CH CH1047973A patent/CH619968A5/de not_active IP Right Cessation
- 1973-07-18 DE DE19732336633 patent/DE2336633A1/de not_active Withdrawn
- 1973-07-18 AU AU58252/73A patent/AU473714B2/en not_active Expired
- 1973-07-18 SE SE7310070A patent/SE396079B/xx unknown
- 1973-07-18 FR FR7326267A patent/FR2192840B2/fr not_active Expired
- 1973-07-18 ZA ZA734896A patent/ZA734896B/xx unknown
- 1973-07-18 LU LU68039A patent/LU68039A1/xx unknown
- 1973-07-18 PH PH14839A patent/PH14795A/en unknown
- 1973-07-18 BE BE133591A patent/BE802481R/xx active
- 1973-07-18 IE IE1223/73A patent/IE37925B1/xx unknown
- 1973-07-18 NL NL7309992A patent/NL7309992A/xx not_active Application Discontinuation
- 1973-07-18 JP JP48082604A patent/JPS5750800B2/ja not_active Expired

Also Published As

Publication number	Publication date
FR2192840B2 (de)	1976-12-24
JPS4980058A (de)	1974-08-02
FR2192840A2 (de)	1974-02-15
NL7309992A (de)	1974-01-22
ZA734896B (en)	1974-12-24
LU68039A1 (de)	1973-09-26
SE396079B (sv)	1977-09-05
ES417012A2 (es)	1976-04-16
AU5825273A (en)	1975-01-23
JPS5750800B2 (de)	1982-10-28
CA1034565A (en)	1978-07-11
AU473714B2 (en)	1976-07-01
IL42779A (en)	1977-04-29
CH619968A5 (de)	1980-10-31
IE37925L (en)	1974-01-19
BE802481R (fr)	1974-01-18
IE37925B1 (en)	1977-11-09
US3856828A (en)	1974-12-24
DK133158B (da)	1976-03-29
PH14795A (en)	1981-12-09
DE2336633A1 (de)	1974-01-31
GB1438940A (en)	1976-06-09

Publication	Publication Date	Title
DK133158C (da)	1976-09-06	Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere
DK132894C (da)	1976-07-26	Analogifremgangsmade til fremstilling af 3-oxo-17alfa-acyloxyandrost-4-en-17beta-carboxylsyreestere
DK145423C (da)	1987-01-12	Fremgangsmaade til fremstilling af amorft udfaeldede kiselsyrepigmenter
DK136900B (da)	1977-12-12	Analogifremgangsmade til fremstilling af usymmetriske 1,4-dihydropyridindicarboxylsyreestere
DK143271C (da)	1981-11-30	Analogifremgangsmaade til fremstilling af 4-phenoxy-phenoxyalkancarboxylsyrederivater
BG27060A3 (bg)	1979-08-15	Сьоръжение за производство на отлети бетонни елементи
DK139361C (da)	1979-07-09	Analogifremgangsmaade til fremstilling af 17alfa-hydroxy-3,20-dioxo-4-pregnen-21-syrer
SE392609B (sv)	1977-04-04	Forfarande for framstellning av metanhaltiga gaser
DK132500C (da)	1976-05-17	Analogifremgangsmade til fremstilling af 2beta,16beta-diamino-5alfa-androstaner
DK139751B (da)	1979-04-09	Analogifremgangsmaade til fremstilling af n-benzhydryl-n!-p-hydroxybenzyl-piperaziner
DK132273C (da)	1976-04-26	Fremgangsmade til fremstilling af trans-chrysanthemsyre
DK135380C (da)	1977-10-03	Analogifremgangsmade til fremstilling af pregnan-21-syrederivater
DK139778B (da)	1979-04-17	Fremgangsmåde til fremstilling af 6-aminopenicillansyre.
DK139524B (da)	1979-03-05	Fremgangsmaade til fremstilling af poly-alfahydroxy-acrylsyre
DK133667B (da)	1976-06-28	Fremgangsmåde til fremstilling af 5-cyklohexyl-6-halogenindan-1-karboxylsyrederivater.
DK551178A (da)	1978-12-06	Analogifremgangsmaade til fremstilling af prostaglandin-analoge
DK133297C (da)	1976-09-20	Analogifremgangsmade til fremstilling af 6-halogen-6-cyklohexylindan-1-karbohydroxamsyre
DK133277B (da)	1976-04-20	Fremgangsmade til fremstilling af transchrysanthemsyre
SE402286B (sv)	1978-06-26	Forfarande for framstellning av substituerade isokinoliner
SE403284B (sv)	1978-08-07	Forfarande for framstellning av uretaner
DK437579A (da)	1979-10-17	Fremgangsmaade til fremstilling af krystallinske pencillinsyrer
DK138447C (da)	1979-02-19	Fremgangsmaade til fremstilling af hexahydro-indan-4-carboxylsyreestere
DK132658C (da)	1976-06-14	Fremgangsmade til fremstilling af sorbinsyre
DK132941C (da)	1976-08-02	Fremgangsmade til fremstilling af 5-cykloalkyl-6-halogen-indan-1-karboxylsyrederivater
DK132283C (da)	1976-04-20	Analogifremgangsmade til fremstilling af 15-oxasteroider

Legal Events

Date	Code	Title	Description
1986-03-17	PBP	Patent lapsed