DK127505B - Analogous process for the preparation of 3,21-dioxygenated 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-ene compounds. - Google Patents

Analogous process for the preparation of 3,21-dioxygenated 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-ene compounds.

Info

Publication number: DK127505B
Authority: DK; Denmark
Prior art keywords: spirox; dihalomethylene; dioxygenated; methylene; preparation
Prior art date: 1969-05-14

Application number

DK377671AA

Other languages

Danish (da)

Inventor

G Arth

G Rasmusson

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-05-14

Filing date

1971-08-02

Publication date

1973-11-19

1971-08-02 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1973-11-19 Publication of DK127505B publication Critical patent/DK127505B/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK377671AA 1969-05-14 1971-08-02 Analogous process for the preparation of 3,21-dioxygenated 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-ene compounds. DK127505B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US82467269A	1969-05-14	1969-05-14
US2118370A	1970-03-19	1970-03-19

Publications (1)

Publication Number	Publication Date
DK127505B true DK127505B (en)	1973-11-19

Family

ID=26694377

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK243670AA DK126992B (en)	1969-05-14	1970-05-13	Analogous process for the preparation of 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-en-3-one compounds.
DK377671AA DK127505B (en)	1969-05-14	1971-08-02	Analogous process for the preparation of 3,21-dioxygenated 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-ene compounds.
DK590571AA DK127880C (en)	1969-05-14	1971-12-02	Analogous process for the preparation of 3-oxo-1,2α-methylene-dihalomethylene-20-spirox-4-ene compounds.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK243670AA DK126992B (en)	1969-05-14	1970-05-13	Analogous process for the preparation of 1,2α-methylene-6,7α-dihalomethylene-20-spirox-4-en-3-one compounds.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK590571AA DK127880C (en)	1969-05-14	1971-12-02	Analogous process for the preparation of 3-oxo-1,2α-methylene-dihalomethylene-20-spirox-4-ene compounds.

Country Status (17)

Country	Link
JP (1)	JPS532865B1 (en)
AR (1)	AR192305A1 (en)
BE (1)	BE750330A (en)
CA (1)	CA926385A (en)
CH (2)	CH547792A (en)
CS (2)	CS151552B2 (en)
DE (1)	DE2023450C3 (en)
DK (3)	DK126992B (en)
FI (2)	FI47355C (en)
FR (1)	FR2051526B1 (en)
GB (1)	GB1265444A (en)
IE (1)	IE34194B1 (en)
IL (1)	IL34431A (en)
NL (1)	NL168844C (en)
NO (1)	NO131131C (en)
SE (2)	SE386904B (en)
YU (1)	YU34052B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3356677A (en) *	1966-04-05	1967-12-05	Syntex Corp	1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

1970
- 1970-05-01 NL NLAANVRAGE7006474,A patent/NL168844C/en not_active IP Right Cessation
- 1970-05-01 CA CA081708A patent/CA926385A/en not_active Expired
- 1970-05-01 IL IL34431A patent/IL34431A/en unknown
- 1970-05-05 IE IE584/70A patent/IE34194B1/en unknown
- 1970-05-06 CH CH683870A patent/CH547792A/en not_active IP Right Cessation
- 1970-05-06 CH CH327973A patent/CH547785A/en not_active IP Right Cessation
- 1970-05-08 YU YU1176/70A patent/YU34052B/en unknown
- 1970-05-11 GB GB1265444D patent/GB1265444A/en not_active Expired
- 1970-05-12 CS CS1070*[A patent/CS151552B2/cs unknown
- 1970-05-12 CS CS3287A patent/CS151551B2/cs unknown
- 1970-05-13 FI FI701339A patent/FI47355C/en active
- 1970-05-13 BE BE750330D patent/BE750330A/en unknown
- 1970-05-13 SE SE7303114A patent/SE386904B/en unknown
- 1970-05-13 SE SE06534/70A patent/SE366305B/xx unknown
- 1970-05-13 NO NO1819/70A patent/NO131131C/no unknown
- 1970-05-13 DK DK243670AA patent/DK126992B/en unknown
- 1970-05-13 DE DE2023450A patent/DE2023450C3/en not_active Expired
- 1970-05-13 FR FR7017446A patent/FR2051526B1/fr not_active Expired
- 1970-05-14 JP JP4055670A patent/JPS532865B1/ja active Pending
1971
- 1971-03-15 AR AR234477A patent/AR192305A1/en active
- 1971-08-02 DK DK377671AA patent/DK127505B/en not_active IP Right Cessation
- 1971-12-02 DK DK590571AA patent/DK127880C/en active
1972
- 1972-10-27 FI FI722993A patent/FI47885C/en active

Also Published As

Publication number	Publication date
DE2023450B2 (en)	1978-10-05
SE386904B (en)	1976-08-23
NL168844C (en)	1982-05-17
CH547792A (en)	1974-04-11
SE366305B (en)	1974-04-22
IL34431A (en)	1974-03-14
FI47355C (en)	1973-11-12
YU117670A (en)	1978-05-15
FI47355B (en)	1973-07-31
CH547785A (en)	1974-04-11
YU34052B (en)	1978-10-31
GB1265444A (en)	1972-03-01
JPS532865B1 (en)	1978-02-01
AR192305A1 (en)	1973-02-14
BE750330A (en)	1970-11-13
DK127880C (en)	1974-06-10
FR2051526A1 (en)	1971-04-09
CA926385A (en)	1973-05-15
FI47885B (en)	1974-01-02
NO131131C (en)	1975-04-09
DK127880B (en)	1974-01-28
NL168844B (en)	1981-12-16
DE2023450C3 (en)	1979-05-31
FR2051526B1 (en)	1974-04-12
CS151552B2 (en)	1973-10-19
IE34194B1 (en)	1975-03-05
DE2023450A1 (en)	1971-01-14
NO131131B (en)	1974-12-30
IE34194L (en)	1970-11-14
IL34431A0 (en)	1970-07-19
FI47885C (en)	1974-04-10
CS151551B2 (en)	1973-10-19
DK126992B (en)	1973-09-10
NL7006474A (en)	1970-11-17

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Legal Events

Date	Code	Title	Description
1984-01-01	PBP	Patent lapsed