DK1133312T3 - Synergistisk anvendelse af thiazolidindioner med glucagonlignende peptid-1 og agonister deraf til behandling af ikke-insulinafhængig diabetes - Google Patents
Synergistisk anvendelse af thiazolidindioner med glucagonlignende peptid-1 og agonister deraf til behandling af ikke-insulinafhængig diabetesInfo
- Publication number
- DK1133312T3 DK1133312T3 DK00938173T DK00938173T DK1133312T3 DK 1133312 T3 DK1133312 T3 DK 1133312T3 DK 00938173 T DK00938173 T DK 00938173T DK 00938173 T DK00938173 T DK 00938173T DK 1133312 T3 DK1133312 T3 DK 1133312T3
- Authority
- DK
- Denmark
- Prior art keywords
- glucagon
- agonists
- peptide
- dependent diabetes
- tzd
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13979499P | 1999-06-21 | 1999-06-21 | |
PCT/US2000/015548 WO2000078333A2 (en) | 1999-06-21 | 2000-06-06 | Synergetic use of thiazolidinediones with glucagon-like peptide-1 and agonists thereof to treat non-insulin dependant diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1133312T3 true DK1133312T3 (da) | 2008-01-02 |
Family
ID=22488329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00938173T DK1133312T3 (da) | 1999-06-21 | 2000-06-06 | Synergistisk anvendelse af thiazolidindioner med glucagonlignende peptid-1 og agonister deraf til behandling af ikke-insulinafhængig diabetes |
Country Status (12)
Country | Link |
---|---|
US (3) | US6660716B1 (da) |
EP (2) | EP1849475A1 (da) |
AT (1) | ATE372782T1 (da) |
AU (1) | AU5325200A (da) |
CA (1) | CA2349865C (da) |
CY (1) | CY1106971T1 (da) |
DE (1) | DE60036367T2 (da) |
DK (1) | DK1133312T3 (da) |
ES (1) | ES2291210T3 (da) |
PT (1) | PT1133312E (da) |
SI (1) | SI1133312T1 (da) |
WO (1) | WO2000078333A2 (da) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US7235627B2 (en) | 1996-08-30 | 2007-06-26 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US20090175821A1 (en) * | 1999-05-17 | 2009-07-09 | Bridon Dominique P | Modified therapeutic peptides with extended half-lives in vivo |
US6514500B1 (en) * | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
EP2280020B1 (en) | 1999-06-29 | 2016-02-17 | MannKind Corporation | Pharmaceutical formulations comprising a peptide complexed with a diketopiperazine |
US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
CA2405709A1 (en) | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
AU2002224124A1 (en) | 2000-12-01 | 2002-06-11 | Takeda Chemical Industries Ltd. | Method for producing preparation containing bioactive substance |
WO2002069994A2 (en) * | 2001-03-07 | 2002-09-12 | Novo Nordisk A/S | Combined use of derivatives of glp-1 analogs and ppar ligands |
PL205971B1 (pl) | 2001-09-24 | 2010-06-30 | Imp Innovations Ltd | Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości |
FR2832064A1 (fr) * | 2001-11-13 | 2003-05-16 | Lipha | Composition pharmaceutique comprenant une glitazone et un derive de thiazolidinedione et son utilisation pour traiter le diabete |
WO2005003296A2 (en) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
ES2545090T3 (es) | 2001-12-21 | 2015-09-08 | Human Genome Sciences, Inc. | Proteínas de fusión de albúmina y GCSF |
ES2259736T3 (es) * | 2001-12-21 | 2006-10-16 | Smithkline Beecham Corporation | Regimen de dosificacion para activadores de ppar-gamma-. |
JP4733922B2 (ja) | 2002-01-10 | 2011-07-27 | インペリアル・イノベ−ションズ・リミテッド | 摂食行動の修正 |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
US8372804B2 (en) * | 2007-10-24 | 2013-02-12 | Mannkind Corporation | Delivery of active agents |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
WO2004050115A2 (en) * | 2002-12-03 | 2004-06-17 | Novo Nordisk A/S | Combination treatment using exendin-4 and thiazolidinediones |
EP1688148A1 (en) * | 2002-12-03 | 2006-08-09 | Novo Nordisk A/S | Combination treatment using exendin-4 and thiazolidinediones |
GB0300571D0 (en) | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
US7638638B2 (en) | 2003-05-14 | 2009-12-29 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
DE602005008497D1 (de) * | 2004-03-15 | 2008-09-11 | Roche Diagnostics Gmbh | Verwendung des BNP-Art und ANP-Art Peptiden für das Festsetzen der Gefahren von Herzgefäß- Komplikationen als Folge der Volumenüberlastung |
EA011168B1 (ru) | 2004-04-23 | 2009-02-27 | Конджачем Биотекнолоджис Инк. | Способ очистки конъюгатов альбумина |
JP2008501714A (ja) | 2004-06-04 | 2008-01-24 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼインヒビター |
WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
KR101306384B1 (ko) | 2004-08-23 | 2013-09-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염 |
WO2007115131A2 (en) * | 2006-03-29 | 2007-10-11 | Guilford F Timothy | Liposomal reduced glutathione and 1-arginine, including other ingredient(s) |
MX381952B (es) | 2005-09-14 | 2025-03-13 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
WO2007053946A1 (en) | 2005-11-09 | 2007-05-18 | Conjuchem Biotechnologies Inc. | Method of treating diabetes and/or obesity with reduced nausea side effects using an insulinotropic peptide conjugated to albumin |
FR2896157B1 (fr) * | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline. |
JP5599975B2 (ja) | 2006-02-22 | 2014-10-01 | マンカインド コーポレイション | ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法 |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
TWI428346B (zh) | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
GEP20125410B (en) * | 2007-02-01 | 2012-02-27 | Takeda Pharmaceutical | Solid preparation comprising alogliptin and pioglitazone |
DK2211842T3 (da) * | 2007-10-24 | 2015-09-21 | Mannkind Corp | En inhalerbar tørpulverformulering omfattende glp-1 til anvendelse i behandlingen af hyperglykæmi og diabetes ved pulmonær administration |
US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
CN102026666B (zh) * | 2007-12-11 | 2013-10-16 | 常山凯捷健生物药物研发(河北)有限公司 | 促胰岛素肽缀合物制剂 |
TW200932223A (en) * | 2007-12-13 | 2009-08-01 | Univ Kyushu Nat Univ Corp | Drug-containing nanoparticles |
KR101762089B1 (ko) | 2008-06-13 | 2017-07-26 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
BRPI1009619B8 (pt) * | 2009-06-05 | 2021-05-25 | Veroscience Llc | forma de dosagem farmacêutica |
US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
MX2011013312A (es) | 2009-06-12 | 2012-01-25 | Mankind Corp | Microparticulas de dicetopiperazina con areas de superficie especificas definidas. |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
ES2625858T3 (es) | 2011-04-01 | 2017-07-20 | Mannkind Corporation | Paquete de tipo blíster para cartuchos farmacéuticos |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CN103945859A (zh) | 2011-10-24 | 2014-07-23 | 曼金德公司 | 用于治疗疼痛的方法和组合物 |
KR20150013838A (ko) | 2012-05-17 | 2015-02-05 | 트랜스테크 파르마 엘엘씨 | 당뇨병 치료를 위한 글루코키나아제 활성화제 조성물 |
US20150157619A1 (en) | 2012-07-10 | 2015-06-11 | Takeda Pharmaceutical Company Limited | Pharmaceutical preparation for injection |
CN108057154B (zh) | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
US20140178456A1 (en) * | 2012-08-30 | 2014-06-26 | Udaya Sankar Devanaboyina | Methods and compositions for treating type 2 diabetes and related conditions |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
WO2014144895A1 (en) | 2013-03-15 | 2014-09-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CN118903385A (zh) | 2017-08-24 | 2024-11-08 | 诺和诺德股份有限公司 | Glp-1组合物及其用途 |
JP2021526130A (ja) | 2018-06-12 | 2021-09-30 | ブイティーブイ・セラピューティクス・エルエルシー | インスリンまたはインスリン類似体と組み合わせたグルコキナーゼ活性化薬の治療的使用 |
PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4349352A (en) * | 1980-08-14 | 1982-09-14 | Rockefeller University | Test for glucosylated hemoglobin and other glucosylated proteins |
US5545618A (en) | 1990-01-24 | 1996-08-13 | Buckley; Douglas I. | GLP-1 analogs useful for diabetes treatment |
DK36392D0 (da) * | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
US5705483A (en) * | 1993-12-09 | 1998-01-06 | Eli Lilly And Company | Glucagon-like insulinotropic peptides, compositions and methods |
GB9409496D0 (en) | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
DE69529998D1 (de) | 1994-12-23 | 2003-04-24 | Novo Nordisk As | Glp-1 zusammensetzungen mit verlängerter wirkdauer |
TW438587B (en) * | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
GB9712866D0 (en) | 1997-06-18 | 1997-08-20 | Smithkline Beecham Plc | Novel method of treatment |
GB9715298D0 (en) | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
EP1056775B1 (en) | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
US6329403B1 (en) | 1998-06-30 | 2001-12-11 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for the treatment of diabetes |
-
2000
- 2000-06-06 DK DK00938173T patent/DK1133312T3/da active
- 2000-06-06 EP EP07111988A patent/EP1849475A1/en not_active Withdrawn
- 2000-06-06 AT AT00938173T patent/ATE372782T1/de active
- 2000-06-06 PT PT00938173T patent/PT1133312E/pt unknown
- 2000-06-06 AU AU53252/00A patent/AU5325200A/en not_active Abandoned
- 2000-06-06 ES ES00938173T patent/ES2291210T3/es not_active Expired - Lifetime
- 2000-06-06 US US09/830,323 patent/US6660716B1/en not_active Ceased
- 2000-06-06 US US11/650,410 patent/USRE40876E1/en not_active Expired - Lifetime
- 2000-06-06 SI SI200030975T patent/SI1133312T1/sl unknown
- 2000-06-06 EP EP00938173A patent/EP1133312B8/en not_active Expired - Lifetime
- 2000-06-06 DE DE60036367T patent/DE60036367T2/de not_active Expired - Lifetime
- 2000-06-06 CA CA2349865A patent/CA2349865C/en not_active Expired - Lifetime
- 2000-06-06 WO PCT/US2000/015548 patent/WO2000078333A2/en active IP Right Grant
-
2003
- 2003-10-06 US US10/679,746 patent/US7223728B2/en not_active Expired - Lifetime
-
2007
- 2007-11-01 CY CY20071101406T patent/CY1106971T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US7223728B2 (en) | 2007-05-29 |
US6660716B1 (en) | 2003-12-09 |
WO2000078333A3 (en) | 2001-07-12 |
EP1133312B8 (en) | 2007-10-17 |
DE60036367D1 (de) | 2007-10-25 |
AU5325200A (en) | 2001-01-09 |
CY1106971T1 (el) | 2012-09-26 |
ATE372782T1 (de) | 2007-09-15 |
WO2000078333A2 (en) | 2000-12-28 |
DE60036367T2 (de) | 2008-05-29 |
CA2349865C (en) | 2014-08-19 |
EP1133312A2 (en) | 2001-09-19 |
SI1133312T1 (sl) | 2008-02-29 |
ES2291210T3 (es) | 2008-03-01 |
USRE40876E1 (en) | 2009-08-18 |
PT1133312E (pt) | 2007-11-30 |
EP1133312B1 (en) | 2007-09-12 |
CA2349865A1 (en) | 2000-12-28 |
EP1849475A1 (en) | 2007-10-31 |
US20040127414A1 (en) | 2004-07-01 |
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