DK1117685T3 - Behandling af inflammatorisk sygdom - Google Patents
Behandling af inflammatorisk sygdomInfo
- Publication number
- DK1117685T3 DK1117685T3 DK99949169T DK99949169T DK1117685T3 DK 1117685 T3 DK1117685 T3 DK 1117685T3 DK 99949169 T DK99949169 T DK 99949169T DK 99949169 T DK99949169 T DK 99949169T DK 1117685 T3 DK1117685 T3 DK 1117685T3
- Authority
- DK
- Denmark
- Prior art keywords
- grp78
- bip
- protein
- treatment
- fragment
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 108700041152 Endoplasmic Reticulum Chaperone BiP Proteins 0.000 abstract 6
- 102100021451 Endoplasmic reticulum chaperone BiP Human genes 0.000 abstract 6
- 101150112743 HSPA5 gene Proteins 0.000 abstract 5
- 101100111629 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) KAR2 gene Proteins 0.000 abstract 5
- 101150028578 grp78 gene Proteins 0.000 abstract 5
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 238000002965 ELISA Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010998 test method Methods 0.000 abstract 1
- 238000001262 western blot Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9822115.3A GB9822115D0 (en) | 1998-10-09 | 1998-10-09 | Treatment of inflammatory disease |
| PCT/GB1999/003316 WO2000021995A1 (en) | 1998-10-09 | 1999-10-08 | Treatment of inflammatory disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1117685T3 true DK1117685T3 (da) | 2007-03-05 |
Family
ID=10840332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99949169T DK1117685T3 (da) | 1998-10-09 | 1999-10-08 | Behandling af inflammatorisk sygdom |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6995240B1 (da) |
| EP (1) | EP1117685B1 (da) |
| JP (1) | JP4435422B2 (da) |
| CN (1) | CN1253470C (da) |
| AT (1) | ATE347561T1 (da) |
| AU (1) | AU754888B2 (da) |
| CA (1) | CA2344590C (da) |
| DE (1) | DE69934324T2 (da) |
| DK (1) | DK1117685T3 (da) |
| ES (1) | ES2277449T3 (da) |
| GB (1) | GB9822115D0 (da) |
| WO (1) | WO2000021995A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7094597B1 (en) * | 1994-05-20 | 2006-08-22 | The Regents Of The University Of California | Vaccine compositions and methods useful in inducing immune protection against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis |
| GB0106161D0 (en) * | 2001-03-13 | 2001-05-02 | King S College London | Immunomodulators |
| NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
| DE10210427A1 (de) * | 2002-03-09 | 2003-10-09 | Hans Konrad Mueller-Hermelink | Humaner monoklonaler Antikörper |
| WO2004005351A2 (en) * | 2002-07-04 | 2004-01-15 | Oncomab Gmbh | Neoplasm specific antibodies and uses thereof |
| DE10311248A1 (de) * | 2003-03-14 | 2004-09-30 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper |
| US20070244304A1 (en) * | 2003-11-12 | 2007-10-18 | Oncomab Gmbh | Methods of Identifying Neoplasm-Specific Antibodies and Uses Thereof |
| DE10353175A1 (de) | 2003-11-14 | 2005-06-16 | Müller-Hermelink, Hans Konrad, Prof. Dr. | Humaner monoklonaler Antikörper mit fettsenkender Wirkung |
| EP1531162A1 (en) * | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Adenocarcinoma specific antibody SAM-6, and uses thereof |
| DE102004015179A1 (de) * | 2004-03-25 | 2005-10-13 | Oncomab Gmbh | Antigen des PM-2 Antikörpers und dessen Verwendung |
| WO2006111720A2 (en) | 2005-04-19 | 2006-10-26 | King's College London | Use |
| US20080199475A1 (en) * | 2006-11-27 | 2008-08-21 | Patrys Limited | Novel glycosylated peptide target in neoplastic cells |
| AU2009207923A1 (en) * | 2008-01-23 | 2009-07-30 | Rigshospitalet | Classification of individuals suffering from cardiovascular diseases according to survival prognoses as found by measuring the levels of biomarker YKL-40 |
| US20110207917A1 (en) * | 2009-02-09 | 2011-08-25 | Patrys Limited | Sam-6 variants, target and methods of use |
| JP2011116719A (ja) * | 2009-12-07 | 2011-06-16 | Univ Of Tokyo | Ｈｌａ−ｄｒ４エピトープの同定と、関節炎治療への応用 |
| GB201603263D0 (en) | 2016-02-25 | 2016-04-13 | King S College London | Biomarkers for response to bip (rasolvir) |
| BR112020025398A2 (pt) | 2018-06-13 | 2021-04-06 | Immune Regulation Limited | Proteína com propriedades anti-inflamatórias |
| IL315962A (en) | 2022-03-31 | 2024-11-01 | Revolo Biotherapeutics Ltd | The compositions and their use in methods for the treatment of intestinal inflammation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5348945A (en) * | 1990-04-06 | 1994-09-20 | Wake Forest University | Method of treatment with hsp70 |
| US5188964A (en) * | 1990-04-12 | 1993-02-23 | Board Of Regents, The University Of Texas System | Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination |
| DK0663010T3 (da) * | 1992-10-02 | 2000-11-13 | Res Corp Technologies Inc | Fremgangsmåde til forøgelse af sekretion af overudtrykte proteiner |
| DE19744132A1 (de) | 1997-10-01 | 1999-04-22 | Stefan Dr Blaes | Anti-Heavy Chain Binding Protein-Antikörper (Anti-BiP-Antikörper) bei rheumatoider Arthritis sowie Verfahren und Testkits zu ihrer Bestimmung in Körperflüssigkeiten |
| DE19817557A1 (de) | 1998-04-09 | 1999-10-21 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Ovartumorgewebe |
-
1998
- 1998-10-09 GB GBGB9822115.3A patent/GB9822115D0/en not_active Ceased
-
1999
- 1999-10-08 CA CA2344590A patent/CA2344590C/en not_active Expired - Fee Related
- 1999-10-08 JP JP2000575897A patent/JP4435422B2/ja not_active Expired - Fee Related
- 1999-10-08 US US09/806,955 patent/US6995240B1/en not_active Expired - Fee Related
- 1999-10-08 DK DK99949169T patent/DK1117685T3/da active
- 1999-10-08 AT AT99949169T patent/ATE347561T1/de not_active IP Right Cessation
- 1999-10-08 ES ES99949169T patent/ES2277449T3/es not_active Expired - Lifetime
- 1999-10-08 DE DE69934324T patent/DE69934324T2/de not_active Expired - Lifetime
- 1999-10-08 EP EP99949169A patent/EP1117685B1/en not_active Expired - Lifetime
- 1999-10-08 WO PCT/GB1999/003316 patent/WO2000021995A1/en not_active Ceased
- 1999-10-08 CN CNB998118427A patent/CN1253470C/zh not_active Expired - Fee Related
- 1999-10-08 AU AU62154/99A patent/AU754888B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69934324D1 (de) | 2007-01-18 |
| WO2000021995A1 (en) | 2000-04-20 |
| JP2003523167A (ja) | 2003-08-05 |
| CN1253470C (zh) | 2006-04-26 |
| AU6215499A (en) | 2000-05-01 |
| US6995240B1 (en) | 2006-02-07 |
| JP4435422B2 (ja) | 2010-03-17 |
| CN1322213A (zh) | 2001-11-14 |
| CA2344590A1 (en) | 2000-04-20 |
| ATE347561T1 (de) | 2006-12-15 |
| CA2344590C (en) | 2011-05-10 |
| EP1117685A1 (en) | 2001-07-25 |
| AU754888B2 (en) | 2002-11-28 |
| GB9822115D0 (en) | 1998-12-02 |
| ES2277449T3 (es) | 2007-07-01 |
| EP1117685B1 (en) | 2006-12-06 |
| DE69934324T2 (de) | 2007-07-05 |
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