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DE69821246D1 - Testverfahren für collagenpeptid - Google Patents

Testverfahren für collagenpeptid

Info

Publication number
DE69821246D1
DE69821246D1 DE69821246T DE69821246T DE69821246D1 DE 69821246 D1 DE69821246 D1 DE 69821246D1 DE 69821246 T DE69821246 T DE 69821246T DE 69821246 T DE69821246 T DE 69821246T DE 69821246 D1 DE69821246 D1 DE 69821246D1
Authority
DE
Germany
Prior art keywords
gly
hyp
ala
level
test procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69821246T
Other languages
English (en)
Other versions
DE69821246T2 (de
Inventor
Stephen M Krane
Michael H Byrne
Hsin-Shan Julia Ju
Scott D Leigh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Metra Biosystems Inc
Original Assignee
General Hospital Corp
Metra Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp, Metra Biosystems Inc filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69821246D1 publication Critical patent/DE69821246D1/de
Publication of DE69821246T2 publication Critical patent/DE69821246T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/108Osteoporosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69821246T 1997-07-31 1998-07-31 Testverfahren für collagenpeptid Expired - Lifetime DE69821246T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5436997P 1997-07-31 1997-07-31
US54369P 1997-07-31
PCT/US1998/016224 WO1999006840A1 (en) 1997-07-31 1998-07-31 Collagen-peptide assay method

Publications (2)

Publication Number Publication Date
DE69821246D1 true DE69821246D1 (de) 2004-02-26
DE69821246T2 DE69821246T2 (de) 2004-11-04

Family

ID=21990562

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69821246T Expired - Lifetime DE69821246T2 (de) 1997-07-31 1998-07-31 Testverfahren für collagenpeptid

Country Status (9)

Country Link
US (1) US5972623A (de)
EP (1) EP1010007B1 (de)
JP (1) JP2001512143A (de)
AT (1) ATE258310T1 (de)
AU (1) AU752227B2 (de)
CA (1) CA2297555A1 (de)
DE (1) DE69821246T2 (de)
ES (1) ES2214722T3 (de)
WO (1) WO1999006840A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333845T3 (es) * 1999-01-06 2010-03-02 University Of Southern California Metodo y composicion para la inhibicion de la angiogenesis.
US20050281821A1 (en) * 1999-01-06 2005-12-22 Flavia Pernasetti Method and composition for angiogenesis inhibition
GB9907234D0 (en) * 1999-03-29 1999-05-26 Isis Innovation Drug assay
EP1203025B1 (de) * 1999-07-13 2009-07-01 University Of Southern California Methode und zusammensetzung zur angiogenese-inhibierung mit antagonisten gegen mmp-9 und beta1-integrine
JP2004510981A (ja) * 2000-10-03 2004-04-08 ロウェット、リサーチ、インスティテュート ピロール含有生体化合物の測定方法およびピロール含有生体化合物
US7365167B2 (en) * 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7390885B2 (en) * 2001-11-26 2008-06-24 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7491691B2 (en) 2002-05-03 2009-02-17 Sindrey Dennis R Connective tissue stimulating peptides
US7488792B2 (en) 2002-08-28 2009-02-10 Burnham Institute For Medical Research Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
US20050124071A1 (en) * 2003-09-30 2005-06-09 Kraus Virginia B. Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating
US20050271650A1 (en) * 2004-02-17 2005-12-08 Cellmatrix, Inc. Method and composition for angiogenesis inhibition
US20070048325A1 (en) * 2005-08-24 2007-03-01 Dennis Van Epps Combination therapies for inhibiting integrin-extracellular matrix interactions
US8198979B2 (en) 2007-04-20 2012-06-12 Ink-Logix, Llc In-molded resistive and shielding elements
WO2008131305A1 (en) 2007-04-20 2008-10-30 Ink-Logix, Llc In-molded capacitive switch
JP4490498B2 (ja) 2008-09-30 2010-06-23 新田ゼラチン株式会社 疾病抑制剤
CN102762224A (zh) * 2009-12-22 2012-10-31 塞尔德克斯医疗公司 疫苗组合物
US9383367B1 (en) 2010-12-07 2016-07-05 Chunli Liu Methods of detecting conjugation site-specific and hidden epitope/antigen
GB201721387D0 (en) * 2017-12-20 2018-01-31 Nordic Bioscience As Tumstatin assay

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628027A (en) * 1982-05-19 1986-12-09 Molecular Engineering Associates, Ltd. Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
GB2208865B (en) * 1987-08-19 1991-12-11 Farmos Group Ltd Purified propeptide of procollagen type iii, antibody to the propeptide and assay method using the antibody.
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US5320970A (en) * 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
WO1989007761A1 (en) * 1988-02-19 1989-08-24 Fuji Yakuhin Kogyo Kabushiki Kaisha Enzyme immunoassay according to sandwich method of human iv-type collagen
GB8815174D0 (en) * 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
GB8929366D0 (en) * 1989-12-30 1990-02-28 Rowett Research Inst Method to detect connective tissue disorder in humans and animals
GB9014220D0 (en) * 1990-06-26 1990-08-15 Farmos Yhtymy Oy Method for the immunlolgical determinition of the carboxyterminal propeptide of type i procollagen
GB9105893D0 (en) * 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
AU684047B2 (en) * 1992-07-31 1997-12-04 Metra Biosystems, Inc. Method and kit for pyridinium crosslink assay
WO1994014072A1 (en) * 1992-12-17 1994-06-23 Metra Biosystems, Inc. Serum pyridinium crosslinks assay
DE9300440U1 (de) * 1993-01-15 1993-03-18 Deutsche Baby-Farben GmbH, 6000 Frankfurt Faltschachtel
DK104093D0 (da) * 1993-09-17 1993-09-17 Osteometer A S Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
GB9506050D0 (en) * 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
WO1996012193A1 (en) * 1994-10-17 1996-04-25 Osteometer Bio Tech A/S Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
US5731409A (en) * 1994-10-28 1998-03-24 Regents Of The University Of Minnesota Polypeptides with type I collagen activity
US5750647A (en) * 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx
EP0829724A1 (de) * 1996-09-17 1998-03-18 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Verfahren zum Nachweis von Kollagenabbau

Also Published As

Publication number Publication date
EP1010007B1 (de) 2004-01-21
CA2297555A1 (en) 1999-02-11
AU752227B2 (en) 2002-09-12
JP2001512143A (ja) 2001-08-21
ATE258310T1 (de) 2004-02-15
EP1010007A1 (de) 2000-06-21
DE69821246T2 (de) 2004-11-04
WO1999006840A1 (en) 1999-02-11
ES2214722T3 (es) 2004-09-16
AU8688898A (en) 1999-02-22
US5972623A (en) 1999-10-26

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