DE69821246D1 - Testverfahren für collagenpeptid - Google Patents
Testverfahren für collagenpeptidInfo
- Publication number
- DE69821246D1 DE69821246D1 DE69821246T DE69821246T DE69821246D1 DE 69821246 D1 DE69821246 D1 DE 69821246D1 DE 69821246 T DE69821246 T DE 69821246T DE 69821246 T DE69821246 T DE 69821246T DE 69821246 D1 DE69821246 D1 DE 69821246D1
- Authority
- DE
- Germany
- Prior art keywords
- gly
- hyp
- ala
- level
- test procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000008186 Collagen Human genes 0.000 title abstract 2
- 108010035532 Collagen Proteins 0.000 title abstract 2
- 229920001436 collagen Polymers 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000010998 test method Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000011382 collagen catabolic process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/108—Osteoporosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5436997P | 1997-07-31 | 1997-07-31 | |
US54369P | 1997-07-31 | ||
PCT/US1998/016224 WO1999006840A1 (en) | 1997-07-31 | 1998-07-31 | Collagen-peptide assay method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69821246D1 true DE69821246D1 (de) | 2004-02-26 |
DE69821246T2 DE69821246T2 (de) | 2004-11-04 |
Family
ID=21990562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69821246T Expired - Lifetime DE69821246T2 (de) | 1997-07-31 | 1998-07-31 | Testverfahren für collagenpeptid |
Country Status (9)
Country | Link |
---|---|
US (1) | US5972623A (de) |
EP (1) | EP1010007B1 (de) |
JP (1) | JP2001512143A (de) |
AT (1) | ATE258310T1 (de) |
AU (1) | AU752227B2 (de) |
CA (1) | CA2297555A1 (de) |
DE (1) | DE69821246T2 (de) |
ES (1) | ES2214722T3 (de) |
WO (1) | WO1999006840A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2333845T3 (es) * | 1999-01-06 | 2010-03-02 | University Of Southern California | Metodo y composicion para la inhibicion de la angiogenesis. |
US20050281821A1 (en) * | 1999-01-06 | 2005-12-22 | Flavia Pernasetti | Method and composition for angiogenesis inhibition |
GB9907234D0 (en) * | 1999-03-29 | 1999-05-26 | Isis Innovation | Drug assay |
EP1203025B1 (de) * | 1999-07-13 | 2009-07-01 | University Of Southern California | Methode und zusammensetzung zur angiogenese-inhibierung mit antagonisten gegen mmp-9 und beta1-integrine |
JP2004510981A (ja) * | 2000-10-03 | 2004-04-08 | ロウェット、リサーチ、インスティテュート | ピロール含有生体化合物の測定方法およびピロール含有生体化合物 |
US7365167B2 (en) * | 2001-11-26 | 2008-04-29 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
US7390885B2 (en) * | 2001-11-26 | 2008-06-24 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
US7491691B2 (en) | 2002-05-03 | 2009-02-17 | Sindrey Dennis R | Connective tissue stimulating peptides |
US7488792B2 (en) | 2002-08-28 | 2009-02-10 | Burnham Institute For Medical Research | Collagen-binding molecules that selectively home to tumor vasculature and methods of using same |
US20050124071A1 (en) * | 2003-09-30 | 2005-06-09 | Kraus Virginia B. | Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating |
US20050271650A1 (en) * | 2004-02-17 | 2005-12-08 | Cellmatrix, Inc. | Method and composition for angiogenesis inhibition |
US20070048325A1 (en) * | 2005-08-24 | 2007-03-01 | Dennis Van Epps | Combination therapies for inhibiting integrin-extracellular matrix interactions |
US8198979B2 (en) | 2007-04-20 | 2012-06-12 | Ink-Logix, Llc | In-molded resistive and shielding elements |
WO2008131305A1 (en) | 2007-04-20 | 2008-10-30 | Ink-Logix, Llc | In-molded capacitive switch |
JP4490498B2 (ja) | 2008-09-30 | 2010-06-23 | 新田ゼラチン株式会社 | 疾病抑制剤 |
CN102762224A (zh) * | 2009-12-22 | 2012-10-31 | 塞尔德克斯医疗公司 | 疫苗组合物 |
US9383367B1 (en) | 2010-12-07 | 2016-07-05 | Chunli Liu | Methods of detecting conjugation site-specific and hidden epitope/antigen |
GB201721387D0 (en) * | 2017-12-20 | 2018-01-31 | Nordic Bioscience As | Tumstatin assay |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4628027A (en) * | 1982-05-19 | 1986-12-09 | Molecular Engineering Associates, Ltd. | Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins |
GB2208865B (en) * | 1987-08-19 | 1991-12-11 | Farmos Group Ltd | Purified propeptide of procollagen type iii, antibody to the propeptide and assay method using the antibody. |
US4973666A (en) * | 1987-11-06 | 1990-11-27 | Washington Research Foundation | Peptide fragments containing HP and LP cross-links |
US5300434A (en) * | 1987-11-06 | 1994-04-05 | Washington Research Foundation | Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide |
US5320970A (en) * | 1987-11-06 | 1994-06-14 | Washington Research Foundation | Detection of collagen degradation in vivo |
WO1989007761A1 (en) * | 1988-02-19 | 1989-08-24 | Fuji Yakuhin Kogyo Kabushiki Kaisha | Enzyme immunoassay according to sandwich method of human iv-type collagen |
GB8815174D0 (en) * | 1988-06-25 | 1988-08-03 | Rowett Research Inst | Method of monitoring collagen degradation |
GB8929366D0 (en) * | 1989-12-30 | 1990-02-28 | Rowett Research Inst | Method to detect connective tissue disorder in humans and animals |
GB9014220D0 (en) * | 1990-06-26 | 1990-08-15 | Farmos Yhtymy Oy | Method for the immunlolgical determinition of the carboxyterminal propeptide of type i procollagen |
GB9105893D0 (en) * | 1991-03-20 | 1991-05-08 | Orion Yhtymae Oy | Bone resorption assay based on a peptide liberated during collagen degradation |
AU684047B2 (en) * | 1992-07-31 | 1997-12-04 | Metra Biosystems, Inc. | Method and kit for pyridinium crosslink assay |
WO1994014072A1 (en) * | 1992-12-17 | 1994-06-23 | Metra Biosystems, Inc. | Serum pyridinium crosslinks assay |
DE9300440U1 (de) * | 1993-01-15 | 1993-03-18 | Deutsche Baby-Farben GmbH, 6000 Frankfurt | Faltschachtel |
DK104093D0 (da) * | 1993-09-17 | 1993-09-17 | Osteometer A S | Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen |
GB9506050D0 (en) * | 1995-03-24 | 1995-05-10 | Osteometer A S | Assaying collagen fragments in body fluids |
WO1996012193A1 (en) * | 1994-10-17 | 1996-04-25 | Osteometer Bio Tech A/S | Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen |
US5731409A (en) * | 1994-10-28 | 1998-03-24 | Regents Of The University Of Minnesota | Polypeptides with type I collagen activity |
US5750647A (en) * | 1995-05-19 | 1998-05-12 | Washington Research Foundation | Synthetic peptide analogs of NTx |
EP0829724A1 (de) * | 1996-09-17 | 1998-03-18 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Verfahren zum Nachweis von Kollagenabbau |
-
1998
- 1998-07-31 ES ES98938343T patent/ES2214722T3/es not_active Expired - Lifetime
- 1998-07-31 US US09/127,286 patent/US5972623A/en not_active Expired - Lifetime
- 1998-07-31 AU AU86888/98A patent/AU752227B2/en not_active Ceased
- 1998-07-31 AT AT98938343T patent/ATE258310T1/de not_active IP Right Cessation
- 1998-07-31 CA CA002297555A patent/CA2297555A1/en not_active Abandoned
- 1998-07-31 WO PCT/US1998/016224 patent/WO1999006840A1/en active IP Right Grant
- 1998-07-31 JP JP2000505519A patent/JP2001512143A/ja active Pending
- 1998-07-31 EP EP98938343A patent/EP1010007B1/de not_active Expired - Lifetime
- 1998-07-31 DE DE69821246T patent/DE69821246T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1010007B1 (de) | 2004-01-21 |
CA2297555A1 (en) | 1999-02-11 |
AU752227B2 (en) | 2002-09-12 |
JP2001512143A (ja) | 2001-08-21 |
ATE258310T1 (de) | 2004-02-15 |
EP1010007A1 (de) | 2000-06-21 |
DE69821246T2 (de) | 2004-11-04 |
WO1999006840A1 (en) | 1999-02-11 |
ES2214722T3 (es) | 2004-09-16 |
AU8688898A (en) | 1999-02-22 |
US5972623A (en) | 1999-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |