DK1109817T3 - Phosphohalogenhydriner, deres fremstilling og anvendelse - Google Patents
Phosphohalogenhydriner, deres fremstilling og anvendelseInfo
- Publication number
- DK1109817T3 DK1109817T3 DK99940247T DK99940247T DK1109817T3 DK 1109817 T3 DK1109817 T3 DK 1109817T3 DK 99940247 T DK99940247 T DK 99940247T DK 99940247 T DK99940247 T DK 99940247T DK 1109817 T3 DK1109817 T3 DK 1109817T3
- Authority
- DK
- Denmark
- Prior art keywords
- phosphohalohydrins
- preparation
- theroef
- cat
- integer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/098—Esters of polyphosphoric acids or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9810913A FR2782721B1 (fr) | 1998-09-01 | 1998-09-01 | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
PCT/FR1999/002058 WO2000012516A1 (fr) | 1998-09-01 | 1999-08-27 | Phosphohalohydrines, procede de fabrication et applications |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1109817T3 true DK1109817T3 (da) | 2002-09-16 |
Family
ID=9530019
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99940247T DK1109817T3 (da) | 1998-09-01 | 1999-08-27 | Phosphohalogenhydriner, deres fremstilling og anvendelse |
Country Status (12)
Country | Link |
---|---|
US (4) | US6660723B1 (da) |
EP (1) | EP1109817B1 (da) |
JP (1) | JP4603163B2 (da) |
AT (1) | ATE218576T1 (da) |
AU (1) | AU5426699A (da) |
CA (1) | CA2341574C (da) |
DE (1) | DE69901717T2 (da) |
DK (1) | DK1109817T3 (da) |
ES (1) | ES2178459T3 (da) |
FR (1) | FR2782721B1 (da) |
PT (1) | PT1109817E (da) |
WO (1) | WO2000012516A1 (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2782722B1 (fr) * | 1998-09-01 | 2001-01-12 | Inst Nat Sante Rech Med | Nouveaux composes phosphoepoxydes, procede de fabrication et applications |
FR2782721B1 (fr) * | 1998-09-01 | 2000-11-03 | Inst Nat Sante Rech Med | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
FR2791981B1 (fr) | 1999-04-06 | 2001-07-20 | Inst Nat Sante Rech Med | Composes inhibant selectivement les lymphocytes tgamma9delta2, et leurs applications |
PT1408984E (pt) * | 2001-07-20 | 2008-12-26 | Bioagency Ag | Compostos organofosforosos para activar células t gama/delta |
US20050042751A1 (en) * | 2001-10-31 | 2005-02-24 | Michel Goldman | Generation and use of new types of dendritic cells |
FR2833266B1 (fr) * | 2001-12-11 | 2004-10-22 | Mayoly Spindler Lab | Nouveaux derives phosphonates, leur procede de preparation, leur utilisation comme modulateurs de l'activite des lymphocytes tgamma9 delta2 |
FR2836483B1 (fr) * | 2002-02-22 | 2006-09-15 | Innate Pharma | Procedes de production de lymphocytes gamma delta t |
GB0212666D0 (en) * | 2002-05-31 | 2002-07-10 | Secr Defence | Immunogenic sequences |
DE60233576D1 (de) * | 2002-12-02 | 2009-10-15 | Innate Pharma | Interleukin-2 und Gamma Delta T Zellaktivator enthaltende Zusammensetzungen und deren Verwendungen |
US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
WO2005077411A2 (en) * | 2004-02-10 | 2005-08-25 | Innate Pharma | Composition and method for the treatment of carcinoma |
WO2005102385A1 (en) | 2004-04-26 | 2005-11-03 | Innate Pharma | Adjuvant composition and methods for its use |
WO2006067635A2 (en) * | 2004-12-20 | 2006-06-29 | Innate Pharma S.A. | USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT |
US7683045B2 (en) * | 2005-03-22 | 2010-03-23 | Innate Pharma S.A. | Class of γδ T cells activators and use thereof |
US20090087456A1 (en) * | 2005-09-07 | 2009-04-02 | James Edward Eyles | Adjuvanted vaccine |
WO2007039635A2 (en) * | 2005-10-06 | 2007-04-12 | Innate Pharma | Phosphoantigen salts of organic bases and methods for their crystallization |
EP1878440A1 (en) * | 2006-07-13 | 2008-01-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for increasing the efficiency of therapeutic antibodies using gamma delta cell activator compounds |
GB2453475B (en) * | 2006-07-25 | 2011-01-19 | Secr Defence | Live vaccine strain |
US20100029674A1 (en) | 2006-11-17 | 2010-02-04 | Innate Pharma, S.A. | Methods of Using Phosphoantigen for the Treatment of Cancer |
EP2123285A1 (en) * | 2008-05-21 | 2009-11-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Nucleosidic phosphoantigens for use in VGAMMA9DELTA2 T cell-mediated therapy |
GB0901423D0 (en) | 2009-01-29 | 2009-03-11 | Secr Defence | Treatment |
GB0901411D0 (en) | 2009-01-29 | 2009-03-11 | Secr Defence | Treatment |
GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
US20150259645A1 (en) * | 2012-11-08 | 2015-09-17 | INSERM (Institut National de la Santé et de la Recherche Médicale | Method for inducing il-2-free proliferation of gamma delta t cells |
KR20210069665A (ko) | 2018-09-27 | 2021-06-11 | 포스포감, 인크. | 동종이계 감마/델타-t 세포의 확장 및 사용을 위한 방법 및 조성물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06228004A (ja) * | 1993-02-05 | 1994-08-16 | Unitika Ltd | 免疫抑制剤およびその製造方法 |
US5639653A (en) * | 1993-07-19 | 1997-06-17 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva Universtiy | Method for proliferating Vγ2Vδ2 T cells |
FR2715660A1 (fr) * | 1994-01-28 | 1995-08-04 | Centre Nat Rech Scient | Composés organo-phosphorés activateurs des lymphocytes Tgammadelta, procédé pour préparer et/ou isoler et/ou caractériser ces composés, compositions et utilisations pharmaceutiques. |
FR2782721B1 (fr) * | 1998-09-01 | 2000-11-03 | Inst Nat Sante Rech Med | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
WO2006067635A2 (en) * | 2004-12-20 | 2006-06-29 | Innate Pharma S.A. | USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT |
-
1998
- 1998-09-01 FR FR9810913A patent/FR2782721B1/fr not_active Expired - Fee Related
-
1999
- 1999-08-27 CA CA2341574A patent/CA2341574C/fr not_active Expired - Fee Related
- 1999-08-27 ES ES99940247T patent/ES2178459T3/es not_active Expired - Lifetime
- 1999-08-27 AU AU54266/99A patent/AU5426699A/en not_active Abandoned
- 1999-08-27 US US09/786,054 patent/US6660723B1/en not_active Expired - Fee Related
- 1999-08-27 PT PT99940247T patent/PT1109817E/pt unknown
- 1999-08-27 WO PCT/FR1999/002058 patent/WO2000012516A1/fr active IP Right Grant
- 1999-08-27 AT AT99940247T patent/ATE218576T1/de active
- 1999-08-27 DK DK99940247T patent/DK1109817T3/da active
- 1999-08-27 EP EP99940247A patent/EP1109817B1/fr not_active Expired - Lifetime
- 1999-08-27 DE DE69901717T patent/DE69901717T2/de not_active Expired - Lifetime
- 1999-08-27 JP JP2000567538A patent/JP4603163B2/ja not_active Expired - Fee Related
-
2003
- 2003-10-14 US US10/682,990 patent/US7109183B2/en not_active Expired - Lifetime
-
2006
- 2006-08-30 US US11/512,688 patent/US7625879B2/en not_active Expired - Fee Related
-
2009
- 2009-11-24 US US12/624,734 patent/US20100068179A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2341574A1 (fr) | 2000-03-09 |
DE69901717T2 (de) | 2003-02-13 |
FR2782721A1 (fr) | 2000-03-03 |
FR2782721B1 (fr) | 2000-11-03 |
EP1109817A1 (fr) | 2001-06-27 |
CA2341574C (fr) | 2011-02-08 |
WO2000012516A1 (fr) | 2000-03-09 |
JP4603163B2 (ja) | 2010-12-22 |
ATE218576T1 (de) | 2002-06-15 |
US7109183B2 (en) | 2006-09-19 |
AU5426699A (en) | 2000-03-21 |
DE69901717D1 (de) | 2002-07-11 |
JP2002523513A (ja) | 2002-07-30 |
US20040087555A1 (en) | 2004-05-06 |
US20060287281A1 (en) | 2006-12-21 |
US7625879B2 (en) | 2009-12-01 |
PT1109817E (pt) | 2002-10-31 |
US20100068179A1 (en) | 2010-03-18 |
US6660723B1 (en) | 2003-12-09 |
EP1109817B1 (fr) | 2002-06-05 |
ES2178459T3 (es) | 2002-12-16 |
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