DK0985697T3 - Oxiranderivater og fremgangsmåde til fremstilling deraf - Google Patents
Oxiranderivater og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK0985697T3 DK0985697T3 DK99909309T DK99909309T DK0985697T3 DK 0985697 T3 DK0985697 T3 DK 0985697T3 DK 99909309 T DK99909309 T DK 99909309T DK 99909309 T DK99909309 T DK 99909309T DK 0985697 T3 DK0985697 T3 DK 0985697T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- oxirane derivatives
- oxirane
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
- C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
- C08G65/2606—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups
- C08G65/2609—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups containing aliphatic hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Polyethers (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7628698 | 1998-03-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0985697T3 true DK0985697T3 (da) | 2006-05-15 |
Family
ID=13601086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99909309T DK0985697T3 (da) | 1998-03-24 | 1999-03-23 | Oxiranderivater og fremgangsmåde til fremstilling deraf |
Country Status (8)
Country | Link |
---|---|
US (1) | US6455639B1 (no) |
EP (1) | EP0985697B1 (no) |
KR (1) | KR100358276B1 (no) |
AU (1) | AU2855499A (no) |
DE (1) | DE69929311T2 (no) |
DK (1) | DK0985697T3 (no) |
NO (1) | NO994392L (no) |
WO (1) | WO1999048948A1 (no) |
Families Citing this family (47)
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---|---|---|---|---|
US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
US6642422B2 (en) * | 1998-06-17 | 2003-11-04 | Nof Corporation | Polyoxyalkylene monoalkyl ether, process for producing the same, polymerizable polyoxyalkylene monoalky ether derivative, polymer of said derivative and dispersant comprising said polymer |
US6780928B1 (en) | 1998-06-17 | 2004-08-24 | Nof Corporation | Polyoxyalkylene monoalkyl ether, process for producing the same, polymerizable polyoxyalkylene monoalkyl ether derivative, polymer of said derivative and dispersant comprising said polymer |
US6921118B2 (en) | 2002-04-22 | 2005-07-26 | Johnson Controls Technology Company | Sliding and nesting console system |
DK2298278T3 (en) | 2002-06-07 | 2016-02-01 | Dyax Corp | Prevention and reduction of blood loss and inflammatory response |
US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
NZ541122A (en) * | 2002-12-26 | 2008-09-26 | Mountain View Pharmaceuticals | Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity |
PL219741B1 (pl) * | 2002-12-26 | 2015-07-31 | Mountain View Pharmaceuticals | Sposób zwiększania antyproliferacyjnego potencjału nieglikozylowanego interferonu-beta-1b in vitro, koniugat wytworzony tym sposobem i jego zastosowanie oraz kompozycja farmaceutyczna zawierająca koniugat i jej zastosowanie |
WO2005010075A2 (en) * | 2003-07-22 | 2005-02-03 | Nektar Therapeutics Al, Corporation | Method for preparing functionalized polymers from polymer alcohols |
CA3050564A1 (en) * | 2003-08-29 | 2005-03-10 | Dyax Corp. | Poly-pegylated protease inhibitors |
US20060045866A1 (en) * | 2004-09-01 | 2006-03-02 | Chris Chappelow | Novel high purity and high molecular weight mPEG alcohol compositions |
US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
US7199193B2 (en) * | 2004-09-28 | 2007-04-03 | Dow Global Technologies, Inc. | Polyethylene glycol compounds and process of making |
KR20070092754A (ko) | 2004-12-27 | 2007-09-13 | 백스터 인터내셔널 인코포레이티드 | 중합체 - 폰 빌레브란트 인자 - 접합체 |
US7824919B2 (en) * | 2005-03-04 | 2010-11-02 | Dr. Reddy's Laboratories Limited | Method for analyzing activated polyethylene glycol compounds |
US8568705B2 (en) | 2005-07-18 | 2013-10-29 | Nektar Therapeutics | Method for preparing branched functionalized polymers using branched polyol cores |
CN100554310C (zh) * | 2006-01-17 | 2009-10-28 | 中国科学院过程工程研究所 | 单烷氧基聚乙二醇及其制备方法 |
CA2647314A1 (en) | 2006-03-31 | 2007-11-08 | Baxter International Inc. | Pegylated factor viii |
US7645860B2 (en) | 2006-03-31 | 2010-01-12 | Baxter Healthcare S.A. | Factor VIII polymer conjugates |
EP2113009B1 (en) * | 2007-02-22 | 2018-11-21 | Biovectra Inc. | Process for purification of water soluble polymers |
EP2150568B1 (en) * | 2007-05-29 | 2016-03-23 | Youl Chon Chemical Co. Ltd. | Chain-end functionalized methoxy poly(ethylene glycol)and metal nano-particles using the same |
CA2696208A1 (en) * | 2007-08-21 | 2009-02-26 | Genzyme Corporation | Treatment with kallikrein inhibitors |
US20100286035A1 (en) * | 2007-10-05 | 2010-11-11 | Takeda Pharmaceutical Company Limited | Neuromedin u derivative |
US20100215092A1 (en) * | 2007-10-05 | 2010-08-26 | Telefonaktiebolaget Lm Ericsson (Publ) | Method and Apparatus for Multiple Description Coding |
KR100922113B1 (ko) | 2007-12-29 | 2009-10-16 | 아이디비켐(주) | 고순도의 벤질옥시폴리에틸렌글리콜 및 그의 유도체의제조방법 |
EP2348064B1 (en) | 2008-11-11 | 2013-08-07 | NOF Corporation | Method for producing polyalkylene glycol derivatives |
JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
TW201029967A (en) * | 2009-02-13 | 2010-08-16 | Nanya Plastics Corp | Method for preparing hindered phenol type antioxidant |
US8501998B2 (en) | 2009-03-31 | 2013-08-06 | Nof Corporation | Method for producing polyoxyalkylene derivative and polyoxyalkylene derivative |
JP5569787B2 (ja) * | 2009-03-31 | 2014-08-13 | 日油株式会社 | 高分子量ポリエチレングリコール化合物の精製方法 |
JP5713274B2 (ja) * | 2009-03-31 | 2015-05-07 | 日油株式会社 | 高分子量ポリオキシアルキレン誘導体の精製方法 |
CN101870728A (zh) | 2009-04-23 | 2010-10-27 | 派格生物医药(苏州)有限公司 | 新型Exendin变体及其缀合物 |
SI2521568T1 (sl) | 2010-01-06 | 2019-01-31 | Dyax Corp. | Proteini, ki vežejo plazemski kalikrein |
TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
KR102502293B1 (ko) | 2011-01-06 | 2023-02-21 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 |
CN104634906B (zh) * | 2013-11-07 | 2018-07-13 | 苏州普源精电科技有限公司 | 分离峰的基线调整方法和具有基线调整功能的色谱工作站 |
CN104634883B (zh) * | 2013-11-07 | 2018-04-27 | 苏州普源精电科技有限公司 | 一种具有融合峰基线调整功能的色谱工作站 |
JP6106103B2 (ja) | 2014-01-16 | 2017-03-29 | 信越化学工業株式会社 | 末端にアミノ基を有する狭分散ポリアルキレングリコール誘導体の製造方法、並びにこれに用いる新規なアセタール基含有アルコール化合物及びそのアルカリ金属塩 |
JP6106104B2 (ja) | 2014-01-16 | 2017-03-29 | 信越化学工業株式会社 | 末端にアミノ基を有する狭分散ポリアルキレングリコール誘導体の製造方法 |
KR20230109785A (ko) | 2014-03-27 | 2023-07-20 | 다케다 파머수티컬 컴패니 리미티드 | 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법 |
US9708350B2 (en) | 2014-12-04 | 2017-07-18 | Shin-Etsu Chemical Co., Ltd. | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator |
US10377775B2 (en) | 2014-12-04 | 2019-08-13 | Shin-Etsu Chemical Co., Ltd. | Method for producing polyalkylene glycol derivative having amino group at end |
WO2017100679A1 (en) | 2015-12-11 | 2017-06-15 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
JP6848743B2 (ja) | 2017-07-24 | 2021-03-24 | 信越化学工業株式会社 | ポリアルキレングリコール誘導体の製造方法及び精製方法 |
DE102018000650A1 (de) * | 2018-01-27 | 2019-08-01 | Friedrich-Schiller-Universität Jena | Verfahren zur Bestimmung von Verunreinigungen in Polyalkylenethern oder Polyalkylenaminen und dessen Verwendung |
CN110964116A (zh) | 2018-09-26 | 2020-04-07 | 北京辅仁瑞辉生物医药研究院有限公司 | GLP1-Fc融合蛋白及其缀合物 |
CN112175088B (zh) | 2019-07-02 | 2023-03-28 | 江苏晟斯生物制药有限公司 | 改进的fix融合蛋白、缀合物及其应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3293193A (en) | 1963-04-09 | 1966-12-20 | Du Pont | Chemical process for production of polyoxyethylene compounds |
JPS6029370B2 (ja) | 1977-03-30 | 1985-07-10 | 株式会社日本触媒 | アルキレンオキシド付加物の製造方法 |
JPS58185622A (ja) * | 1982-04-23 | 1983-10-29 | Shiseido Co Ltd | 非感作性ポリオキシエチレンアルキルエ−テル酢酸塩及びその製造法 |
US4721816A (en) * | 1985-12-23 | 1988-01-26 | Shell Oil Company | Preparation of nonionic surfactants |
JP2552513B2 (ja) | 1987-12-04 | 1996-11-13 | 川研ファインケミカル株式会社 | (ポリ)オキシエチレンアルキルエーテル化合物の酸化方法 |
US4967016A (en) * | 1989-05-19 | 1990-10-30 | Shell Oil Company | Alkoxylation process catalyzed by barium phosphate |
JPH04214722A (ja) | 1990-12-14 | 1992-08-05 | Asahi Glass Co Ltd | ポリエーテル類の製造方法 |
US5605976A (en) * | 1995-05-15 | 1997-02-25 | Enzon, Inc. | Method of preparing polyalkylene oxide carboxylic acids |
JP3562000B2 (ja) * | 1994-12-14 | 2004-09-08 | 日本油脂株式会社 | ポリオキシアルキレンモノアミンの製造方法 |
JP3174479B2 (ja) * | 1995-03-28 | 2001-06-11 | ライオン株式会社 | 活性水素を有する化合物のアルキレンオキサイド付加物の製造方法 |
JP3933747B2 (ja) * | 1996-06-05 | 2007-06-20 | 三菱化学株式会社 | 環状エーテルの重合方法 |
JPH10168177A (ja) * | 1996-12-12 | 1998-06-23 | Mitsubishi Chem Corp | 金属塩及びその製造方法 |
JP4099835B2 (ja) | 1997-03-24 | 2008-06-11 | 日産自動車株式会社 | Camによる金型の穴形状形成方法 |
-
1999
- 1999-03-23 DE DE69929311T patent/DE69929311T2/de not_active Expired - Lifetime
- 1999-03-23 KR KR1019997008317A patent/KR100358276B1/ko not_active IP Right Cessation
- 1999-03-23 EP EP99909309A patent/EP0985697B1/en not_active Revoked
- 1999-03-23 US US09/367,642 patent/US6455639B1/en not_active Expired - Lifetime
- 1999-03-23 AU AU28554/99A patent/AU2855499A/en not_active Abandoned
- 1999-03-23 WO PCT/JP1999/001451 patent/WO1999048948A1/ja active IP Right Grant
- 1999-03-23 DK DK99909309T patent/DK0985697T3/da active
- 1999-09-10 NO NO19994392A patent/NO994392L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO994392L (no) | 2000-01-24 |
DE69929311D1 (de) | 2006-03-30 |
NO994392D0 (no) | 1999-09-10 |
EP0985697B1 (en) | 2006-01-04 |
EP0985697A1 (en) | 2000-03-15 |
US6455639B1 (en) | 2002-09-24 |
KR100358276B1 (ko) | 2002-10-25 |
DE69929311T2 (de) | 2006-09-07 |
AU2855499A (en) | 1999-10-18 |
EP0985697A4 (en) | 2001-10-17 |
US20020120075A1 (en) | 2002-08-29 |
KR20000076223A (ko) | 2000-12-26 |
WO1999048948A1 (fr) | 1999-09-30 |
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