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DK0948358T4 - Stabile inteferon-væskeformuleringer - Google Patents

Stabile inteferon-væskeformuleringer

Info

Publication number
DK0948358T4
DK0948358T4 DK97952621.7T DK97952621T DK0948358T4 DK 0948358 T4 DK0948358 T4 DK 0948358T4 DK 97952621 T DK97952621 T DK 97952621T DK 0948358 T4 DK0948358 T4 DK 0948358T4
Authority
DK
Denmark
Prior art keywords
liquid
interferon
compositions
inteferon
stable
Prior art date
Application number
DK97952621.7T
Other languages
English (en)
Other versions
DK0948358T3 (da
Inventor
Mary D Dibiasi
Mark Staples
Wen-Li Chung
Eric Scharin
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21875893&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0948358(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of DK0948358T3 publication Critical patent/DK0948358T3/da
Application granted granted Critical
Publication of DK0948358T4 publication Critical patent/DK0948358T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97952621.7T 1996-12-24 1997-12-23 Stabile inteferon-væskeformuleringer DK0948358T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3435396P 1996-12-24 1996-12-24
PCT/US1997/023817 WO1998028007A1 (en) 1996-12-24 1997-12-23 Stable liquid interferon formulations

Publications (2)

Publication Number Publication Date
DK0948358T3 DK0948358T3 (da) 2004-11-08
DK0948358T4 true DK0948358T4 (da) 2012-03-19

Family

ID=21875893

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97952621.7T DK0948358T4 (da) 1996-12-24 1997-12-23 Stabile inteferon-væskeformuleringer

Country Status (28)

Country Link
EP (1) EP0948358B2 (da)
JP (5) JP4878664B2 (da)
KR (2) KR20000069664A (da)
CN (2) CN1733296B (da)
AT (1) ATE270899T1 (da)
AU (1) AU738362B2 (da)
BG (2) BG65418B1 (da)
BR (1) BR9714434A (da)
CA (1) CA2275890C (da)
CZ (1) CZ300636B6 (da)
DE (1) DE69729880T3 (da)
DK (1) DK0948358T4 (da)
EA (1) EA002754B1 (da)
EE (2) EE04223B1 (da)
ES (1) ES2224290T5 (da)
HK (2) HK1025040A1 (da)
HU (1) HU224222B1 (da)
IL (1) IL130524A (da)
IS (1) IS2070B (da)
MX (1) MX337876B (da)
NO (1) NO327844B1 (da)
NZ (2) NZ336548A (da)
PL (1) PL193447B1 (da)
PT (1) PT948358E (da)
SI (1) SI0948358T2 (da)
SK (1) SK284989B6 (da)
TR (1) TR199901968T2 (da)
WO (1) WO1998028007A1 (da)

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US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
AR034749A1 (es) * 2001-07-09 2004-03-17 Schering Ag Formulaciones de interferon beta humano
CN1607958A (zh) 2001-12-21 2005-04-20 诺和诺德医疗保健公司 因子ⅶ多肽的液体组合物
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CN1780638B (zh) 2003-05-23 2010-04-14 诺和诺德医疗保健公司 氧化硅涂层玻璃作为容器内壁材料的用途及以该材料作内壁的容器
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KR101149454B1 (ko) * 2004-08-24 2012-05-25 간가와 겐지 생리활성 펩티드의 액상 제제
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PL1845925T3 (pl) * 2005-01-12 2017-05-31 Biogen Ma Inc. Sposób podawania interferonu beta
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KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
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DE102008051574A1 (de) 2008-10-14 2010-04-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Herstellung von Interferon-beta und deren Varianten
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DE102010011430A1 (de) * 2010-03-15 2011-09-15 Kurt Koch Verfahren für den Bau des Nullenergiehauses in Schalenbauweise durch Ausschäumen aller Wände, Decken und Bedachung
MX366325B (es) 2010-05-05 2019-07-05 Boehringer Ingelheim Int Terapia de combinacion.
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AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
JP5538568B2 (ja) * 2010-12-09 2014-07-02 丸石製薬株式会社 アセトアミノフェンの安定化剤
PT2686002T (pt) 2011-03-15 2018-04-23 Biogen Inc Método para reduzir sintomas gripais associados à administração intramuscular de interferon utilizando um regime de dosagem crescente de titulação rápida
PL3517539T3 (pl) 2011-07-15 2023-04-24 Boehringer Ingelheim International Gmbh Podstawiona dimeryczna pochodna chinazoliny, sposób jej wytwarzania i jej zastosowanie w kompozycjach farmaceutycznych do leczenia cukrzycy typu I i II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
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ITMI20120913A1 (it) 2012-05-28 2013-11-29 Nicoletta Maxia Uso della n-acetil-5-metossitriptamina o suoi analoghi per favorire il meccanismo di impianto dell' embrione, e relative composizioni e mezzi di coltura
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CN109310697A (zh) 2016-06-10 2019-02-05 勃林格殷格翰国际有限公司 利格列汀和二甲双胍的组合
KR101943160B1 (ko) * 2016-10-06 2019-01-30 에이비온 주식회사 인터페론 베타 변이체의 안정화 제제
ES2945165T3 (es) 2017-08-22 2023-06-28 Biogen Ma Inc Composiciones farmacéuticas que contienen anticuerpos anti-beta-amiloides
KR102731889B1 (ko) * 2019-07-18 2024-11-19 에이비온 주식회사 2당화된 인터페론-베타 단백질의 정제 방법
CN110714051B (zh) * 2019-11-20 2023-04-07 迈克生物股份有限公司 蛋白c活性测定试剂盒
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CN114177273B (zh) * 2021-11-29 2024-05-28 苏州人本药业有限公司 一种含有神经毒素的液体制剂及其制备方法
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Also Published As

Publication number Publication date
WO1998028007A1 (en) 1998-07-02
ES2224290T3 (es) 2005-03-01
ATE270899T1 (de) 2004-07-15
NO327844B1 (no) 2009-10-05
DE69729880T2 (de) 2005-07-07
BR9714434A (pt) 2000-05-02
TR199901968T2 (xx) 1999-12-21
HU224222B1 (hu) 2005-06-28
CZ300636B6 (cs) 2009-07-08
SK284989B6 (sk) 2006-04-06
CN1245434A (zh) 2000-02-23
IL130524A (en) 2005-08-31
EA199900597A1 (ru) 2000-02-28
IS5087A (is) 1999-06-21
ES2224290T5 (es) 2012-03-12
JP2014098029A (ja) 2014-05-29
SK85899A3 (en) 2000-01-18
CN1222315C (zh) 2005-10-12
PL334365A1 (en) 2000-02-28
KR101042660B1 (ko) 2011-06-20
BG65171B1 (bg) 2007-05-31
EP0948358B2 (en) 2011-11-23
NZ336548A (en) 2001-09-28
EE04223B1 (et) 2004-02-16
CZ228299A3 (cs) 1999-12-15
IL130524A0 (en) 2000-06-01
HK1092048A1 (en) 2007-02-02
SI0948358T2 (sl) 2012-03-30
DE69729880D1 (de) 2004-08-19
JP2012006979A (ja) 2012-01-12
DE69729880T3 (de) 2012-05-10
KR20000069664A (ko) 2000-11-25
IS2070B (is) 2005-12-15
AU5619198A (en) 1998-07-17
SI0948358T1 (en) 2005-04-30
HUP0000829A3 (en) 2002-01-28
CN1733296B (zh) 2010-05-26
BG103594A (en) 2000-04-28
AU738362B2 (en) 2001-09-13
HK1025040A1 (en) 2000-11-03
EE200300127A (et) 2003-06-16
PT948358E (pt) 2004-10-29
CN1733296A (zh) 2006-02-15
JP2001519770A (ja) 2001-10-23
EP0948358A1 (en) 1999-10-13
CA2275890A1 (en) 1998-07-02
BG109523A (en) 2007-05-31
EA002754B1 (ru) 2002-08-29
KR20070052363A (ko) 2007-05-21
BG65418B1 (bg) 2008-07-31
NO993121D0 (no) 1999-06-23
MX337876B (es) 2016-03-22
JP5851695B2 (ja) 2016-02-03
DK0948358T3 (da) 2004-11-08
HUP0000829A2 (en) 2000-07-28
CA2275890C (en) 2011-11-01
PL193447B1 (pl) 2007-02-28
EE04266B1 (et) 2004-04-15
EE9900313A (et) 2000-04-17
JP2011068694A (ja) 2011-04-07
JP4878664B2 (ja) 2012-02-15
NZ512792A (en) 2002-11-26
JP2007204501A (ja) 2007-08-16
EP0948358B1 (en) 2004-07-14
NO993121L (no) 1999-08-24

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