DK0941221T3 - Substituerede dihydrobenzofuraner som PDE-inhibitorer - Google Patents
Substituerede dihydrobenzofuraner som PDE-inhibitorerInfo
- Publication number
- DK0941221T3 DK0941221T3 DK97950157T DK97950157T DK0941221T3 DK 0941221 T3 DK0941221 T3 DK 0941221T3 DK 97950157 T DK97950157 T DK 97950157T DK 97950157 T DK97950157 T DK 97950157T DK 0941221 T3 DK0941221 T3 DK 0941221T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- pde inhibitors
- substituted dihydrobenzofurans
- dihydrobenzofurans
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19647881 | 1996-11-20 | ||
EP96118743 | 1996-11-22 | ||
PCT/EP1997/006248 WO1998022453A1 (en) | 1996-11-20 | 1997-11-11 | Substituted dihydrobenzofurans as pde inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0941221T3 true DK0941221T3 (da) | 2003-06-10 |
Family
ID=26031440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97950157T DK0941221T3 (da) | 1996-11-20 | 1997-11-11 | Substituerede dihydrobenzofuraner som PDE-inhibitorer |
Country Status (12)
Country | Link |
---|---|
US (1) | US6054475A (da) |
EP (1) | EP0941221B1 (da) |
JP (1) | JP2001505198A (da) |
AT (1) | ATE233252T1 (da) |
AU (1) | AU5320698A (da) |
CY (1) | CY2472B1 (da) |
DE (1) | DE69719358T2 (da) |
DK (1) | DK0941221T3 (da) |
ES (1) | ES2193414T3 (da) |
PT (1) | PT941221E (da) |
SI (1) | SI0941221T1 (da) |
WO (1) | WO1998022453A1 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999021558A2 (en) * | 1997-10-28 | 1999-05-06 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
ATE320800T1 (de) | 1999-08-21 | 2006-04-15 | Altana Pharma Ag | Synergistische kombination von roflumilast und salmeterol |
KR20030007575A (ko) * | 2000-05-03 | 2003-01-23 | 수캄포 아게 | 안압 강하제 |
SE0004780D0 (sv) * | 2000-12-22 | 2000-12-22 | Jordanian Pharmaceutical Mfg & | Novel compunds |
JP3940290B2 (ja) * | 2000-12-22 | 2007-07-04 | ザ・ヨルダニアン・フアーマシユーテイカル・エム・エフ・ジー・アンド・メデイカル・イクイツプメント・カンパニー・リミテツド | 新規化合物 |
DE60208630T2 (de) * | 2001-05-11 | 2006-08-17 | Pfizer Products Inc., Groton | Thiazolderivate und ihre Verwendung als cdk-Inhibitoren |
IL162602A0 (en) | 2001-12-20 | 2005-11-20 | Applied Research Systems | Pyrrolidine derivatives as prostaglandin modulators |
US6723755B2 (en) | 2002-06-12 | 2004-04-20 | Piotr Chomczynski | Method of treating rosacea |
EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
DE10348022A1 (de) * | 2003-10-15 | 2005-05-25 | Imtm Gmbh | Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
US7812057B2 (en) * | 2004-08-25 | 2010-10-12 | Molecular Research Center, Inc. | Cosmetic compositions |
EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
EP1928437A2 (en) | 2005-08-26 | 2008-06-11 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
MX2009002496A (es) | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
US20150119399A1 (en) | 2012-01-10 | 2015-04-30 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU677776B2 (en) * | 1992-04-02 | 1997-05-08 | Smithkline Beecham Corporation | Compounds useful for treating allergic and inflammatory diseases |
US6121274A (en) * | 1994-07-22 | 2000-09-19 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Dihydrobenzofurane |
DE59610031D1 (de) * | 1995-05-18 | 2003-02-06 | Altana Pharma Ag | Cyclohexyldihydrobenzofurane |
DK0828728T3 (da) * | 1995-05-18 | 2003-05-19 | Altana Pharma Ag | Phenyldihydrobenzofuraner |
-
1997
- 1997-11-11 AU AU53206/98A patent/AU5320698A/en not_active Abandoned
- 1997-11-11 EP EP97950157A patent/EP0941221B1/en not_active Expired - Lifetime
- 1997-11-11 JP JP52316498A patent/JP2001505198A/ja not_active Ceased
- 1997-11-11 ES ES97950157T patent/ES2193414T3/es not_active Expired - Lifetime
- 1997-11-11 SI SI9730523T patent/SI0941221T1/xx unknown
- 1997-11-11 DE DE69719358T patent/DE69719358T2/de not_active Expired - Fee Related
- 1997-11-11 DK DK97950157T patent/DK0941221T3/da active
- 1997-11-11 US US09/284,459 patent/US6054475A/en not_active Expired - Fee Related
- 1997-11-11 PT PT97950157T patent/PT941221E/pt unknown
- 1997-11-11 AT AT97950157T patent/ATE233252T1/de not_active IP Right Cessation
- 1997-11-11 WO PCT/EP1997/006248 patent/WO1998022453A1/en active IP Right Grant
-
2004
- 2004-08-11 CY CY0400063A patent/CY2472B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0941221A1 (en) | 1999-09-15 |
CY2472B1 (en) | 2005-06-03 |
JP2001505198A (ja) | 2001-04-17 |
EP0941221B1 (en) | 2003-02-26 |
AU5320698A (en) | 1998-06-10 |
US6054475A (en) | 2000-04-25 |
ATE233252T1 (de) | 2003-03-15 |
SI0941221T1 (en) | 2003-10-31 |
PT941221E (pt) | 2003-07-31 |
ES2193414T3 (es) | 2003-11-01 |
DE69719358T2 (de) | 2003-12-24 |
WO1998022453A1 (en) | 1998-05-28 |
DE69719358D1 (de) | 2003-04-03 |
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