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DK0914103T3 - Behandling af hæmoglobinopati - Google Patents

Behandling af hæmoglobinopati

Info

Publication number
DK0914103T3
DK0914103T3 DK97920137T DK97920137T DK0914103T3 DK 0914103 T3 DK0914103 T3 DK 0914103T3 DK 97920137 T DK97920137 T DK 97920137T DK 97920137 T DK97920137 T DK 97920137T DK 0914103 T3 DK0914103 T3 DK 0914103T3
Authority
DK
Denmark
Prior art keywords
hemoglobinopathy
treatment
Prior art date
Application number
DK97920137T
Other languages
English (en)
Inventor
Warren M Zapol
C Alvin Head
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of DK0914103T3 publication Critical patent/DK0914103T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK97920137T 1996-04-05 1997-04-03 Behandling af hæmoglobinopati DK0914103T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1488696P 1996-04-05 1996-04-05

Publications (1)

Publication Number Publication Date
DK0914103T3 true DK0914103T3 (da) 2006-10-23

Family

ID=21768361

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97920137T DK0914103T3 (da) 1996-04-05 1997-04-03 Behandling af hæmoglobinopati

Country Status (15)

Country Link
US (1) US5885621A (da)
EP (1) EP0914103B1 (da)
JP (1) JP2000510448A (da)
CN (1) CN1208053C (da)
AP (1) AP897A (da)
AT (1) ATE331505T1 (da)
AU (1) AU720686B2 (da)
BR (1) BR9708601A (da)
CA (1) CA2251530C (da)
DE (1) DE69736230T2 (da)
DK (1) DK0914103T3 (da)
ES (1) ES2267141T3 (da)
OA (1) OA10893A (da)
PT (1) PT914103E (da)
WO (1) WO1997037644A1 (da)

Families Citing this family (59)

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US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US6627738B2 (en) 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
US6911427B1 (en) 1995-09-15 2005-06-28 Duke University No-modified hemoglobins and uses therefore
US6197745B1 (en) 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US8128963B2 (en) * 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US6656452B1 (en) 1997-10-21 2003-12-02 The General Hospital Corporation Use of inhaled NO as anti-inflammatory agent
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
CA2254645A1 (en) * 1998-11-23 2000-05-23 Pulmonox Medical Corporation Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
US7678390B2 (en) 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
FR2794647A1 (fr) * 1999-06-11 2000-12-15 Centre Nat Rech Scient Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6601580B1 (en) * 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation
FR2812197B1 (fr) * 2000-07-27 2003-01-03 Air Liquide Sante Int Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches
FR2816212A1 (fr) * 2000-11-03 2002-05-10 Air Liquide Sante Int Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7335181B2 (en) * 2000-12-26 2008-02-26 Pulmonox Technologies Corporation Nitric oxide decontamination of the upper respiratory tract
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
NZ562962A (en) * 2001-06-21 2009-08-28 Fritz H Bach Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
EP1476168A2 (en) * 2002-02-04 2004-11-17 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US7364757B2 (en) * 2002-02-13 2008-04-29 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating vascular disease
RS91104A (sr) * 2002-04-15 2007-02-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Postupci za lečenje nekrotizujućeg enterokolitisa
AU2003226366A1 (en) 2002-04-15 2003-11-03 Beth Israel Deaconess Medical Center Use of heme oxygenase-1 and products of heme degradation
HRP20040972A2 (en) * 2002-04-15 2005-06-30 University Of Pittsburgh Of The Commonwealth Systeyale University Methods of treating ileus
PL205066B1 (pl) 2002-05-17 2010-03-31 Univ Pittsburgh Zastosowanie tlenku węgla do wytwarzania kompozycji farmaceutycznej
PL374375A1 (en) * 2002-06-05 2005-10-17 Yale University Methods of treating angiogenesis, tumor growth, and metastasis
EA200500062A1 (ru) * 2002-06-21 2005-06-30 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Фармацевтическое применение оксида азота, гемоксигеназы-1 и продуктов деградации гема
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
RS20050344A (sr) * 2002-11-07 2007-11-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Tretiranje hemoragijskog šoka
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20070207217A1 (en) * 2003-02-03 2007-09-06 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO
AU2004255268B2 (en) * 2003-07-09 2010-04-01 Loma Linda University Use of nitrite salts for the treatment of cardiovascular conditions
WO2005077005A2 (en) * 2004-02-04 2005-08-25 The General Hospital Corporation Enhancing the effectiveness of an inhaled therapeutic gas
AU2005244078A1 (en) * 2004-05-11 2005-11-24 Pulmonox Technologies Corporation Intermittent dosing of nitric oxide gas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US20070116785A1 (en) * 2005-11-18 2007-05-24 Miller Christopher C Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
TWI474824B (zh) * 2006-11-07 2015-03-01 Gen Hospital Corp 血管活性氧載劑所引發之血管收縮之減輕
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
EP2237788A4 (en) * 2007-12-27 2013-06-05 Aires Pharmaceuticals Inc COMPOUNDS FOR OBTAINING AEROSOLIZED NITRITE AND NITRIC OXIDE AND USES THEREOF
LT2435121T (lt) 2009-05-27 2017-07-25 Ino Therapeutics Llc Įrenginys, skirtas sugraduoto vožtuvo ir hermetiško kanistro įrenginio sukabinimui be sandariklio
JP2011010865A (ja) 2009-06-30 2011-01-20 Ikaria Holdings Inc 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法
US20120201906A1 (en) * 2009-09-08 2012-08-09 Reynolds James D Novel medical uses for no and no donor compounds
WO2012145520A2 (en) 2011-04-19 2012-10-26 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
ES2628634T3 (es) 2011-07-21 2017-08-03 Alfama, Inc. Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas
US9573110B2 (en) 2011-10-03 2017-02-21 NitricGen, Inc. Apparatus and method for generating nitric oxide in controlled and accurate amounts
WO2013070592A1 (en) 2011-11-07 2013-05-16 The General Hospital Corporation Treatment of red blood cells
DK2822564T3 (da) 2012-03-07 2018-11-19 Advanced Inhalation Therapies Ait Ltd Inhalering af nitrogenoxid til behandling af luftvejssygdomme
WO2013138654A1 (en) 2012-03-15 2013-09-19 Ino Therapeutics Llc Methods of administering high concentrations of nitric oxide
WO2019173283A1 (en) 2018-03-05 2019-09-12 Marquette University Method and apparatus for non-invasive hemoglobin level prediction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954526A (en) * 1989-02-28 1990-09-04 The United States Of America As Represented By The Department Of Health And Human Services Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5380945A (en) * 1989-06-21 1995-01-10 Abbott Laboratories Guanidino compounds as regulators of nitric oxide synthase
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
ES2082732T3 (es) * 1990-12-05 1997-12-16 Gen Hospital Corp Tratamiento de la vasoconstriccion pulmonar reversible y de la broncoconstriccion.
DK0726768T3 (da) * 1993-11-02 2000-10-02 Us Health Anvendelse af nitrogenoxidfrigørende forbindelser til fremstillingen af et medikament til beskyttelse i iskæmisk reperfusio

Also Published As

Publication number Publication date
BR9708601A (pt) 1999-08-03
ES2267141T3 (es) 2007-03-01
DE69736230T2 (de) 2007-05-31
US5885621A (en) 1999-03-23
CA2251530A1 (en) 1997-10-16
EP0914103B1 (en) 2006-06-28
AU2440397A (en) 1997-10-29
ATE331505T1 (de) 2006-07-15
CA2251530C (en) 2002-11-19
CN1227485A (zh) 1999-09-01
AP897A (en) 2000-11-17
WO1997037644A1 (en) 1997-10-16
EP0914103A4 (en) 2003-09-03
EP0914103A1 (en) 1999-05-12
CN1208053C (zh) 2005-06-29
OA10893A (en) 2001-10-11
AU720686B2 (en) 2000-06-08
DE69736230D1 (de) 2006-08-10
AP9801358A0 (en) 1998-12-31
JP2000510448A (ja) 2000-08-15
PT914103E (pt) 2006-09-29

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