BR9708601A - Tratamento de uma hemoglobinopatia - Google Patents

Tratamento de uma hemoglobinopatia

Info

Publication number: BR9708601A
Authority: BR; Brazil
Prior art keywords: hemoglobinopathy; treatment
Prior art date: 1996-04-05

Application number

BR9708601A

Other languages

English (en)

Inventor

Alvin C Head

Warren M Zapol

Original Assignee

Gen Hospital Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-05

Filing date

1997-04-03

Publication date

1999-08-03

1997-04-03 Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp

1999-08-03 Publication of BR9708601A publication Critical patent/BR9708601A/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Emergency Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

BR9708601A 1996-04-05 1997-04-03 Tratamento de uma hemoglobinopatia BR9708601A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1488696P	1996-04-05	1996-04-05
PCT/US1997/005633 WO1997037644A1 (en)	1996-04-05	1997-04-03	Treatment of a hemoglobinopathy

Publications (1)

Publication Number	Publication Date
BR9708601A true BR9708601A (pt)	1999-08-03

Family

ID=21768361

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9708601A BR9708601A (pt)	1996-04-05	1997-04-03	Tratamento de uma hemoglobinopatia

Country Status (15)

Country	Link
US (1)	US5885621A (pt)
EP (1)	EP0914103B1 (pt)
JP (1)	JP2000510448A (pt)
CN (1)	CN1208053C (pt)
AP (1)	AP897A (pt)
AT (1)	ATE331505T1 (pt)
AU (1)	AU720686B2 (pt)
BR (1)	BR9708601A (pt)
CA (1)	CA2251530C (pt)
DE (1)	DE69736230T2 (pt)
DK (1)	DK0914103T3 (pt)
ES (1)	ES2267141T3 (pt)
OA (1)	OA10893A (pt)
PT (1)	PT914103E (pt)
WO (1)	WO1997037644A1 (pt)

Families Citing this family (58)

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US6063407A (en) *	1995-02-16	2000-05-16	The General Hospital Corporation	Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US6627738B2 (en)	1995-09-15	2003-09-30	Duke University	No-modified hemoglobins and uses therefor
US6911427B1 (en)	1995-09-15	2005-06-28	Duke University	No-modified hemoglobins and uses therefore
US6197745B1 (en)	1995-09-15	2001-03-06	Duke University	Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US8128963B2 (en) *	1996-09-27	2012-03-06	The Trustees Of Columbia University In The City Of New York	Methods for treating ischemic disorders using carbon monoxide
US6656452B1 (en)	1997-10-21	2003-12-02	The General Hospital Corporation	Use of inhaled NO as anti-inflammatory agent
US20070086954A1 (en) *	1998-11-23	2007-04-19	Miller Christopher C	Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
CA2254645A1 (en) *	1998-11-23	2000-05-23	Pulmonox Medical Corporation	Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
US7678390B2 (en)	1999-04-01	2010-03-16	Yale University	Carbon monoxide as a biomarker and therapeutic agent
FR2794647A1 (fr) *	1999-06-11	2000-12-15	Centre Nat Rech Scient	Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
US7516742B2 (en) *	1999-11-24	2009-04-14	Cardinal Health 207, Inc.	Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6601580B1 (en) *	2000-06-28	2003-08-05	The General Hospital Corporation	Enhancing therapeutic effectiveness of nitric oxide inhalation
FR2812197B1 (fr) *	2000-07-27	2003-01-03	Air Liquide Sante Int	Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches
FR2816212A1 (fr) *	2000-11-03	2002-05-10	Air Liquide Sante Int	Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire
US7335181B2 (en) *	2000-12-26	2008-02-26	Pulmonox Technologies Corporation	Nitric oxide decontamination of the upper respiratory tract
US6432077B1 (en) *	2000-12-26	2002-08-13	Sensormedics Corporation	Device and method for treatment of surface infections with nitric oxide
US7122018B2 (en) *	2000-12-26	2006-10-17	Sensormedics Corporation	Device and method for treatment of wounds with nitric oxide
GB0111872D0 (en) *	2001-05-15	2001-07-04	Northwick Park Inst For Medica	Therapeutic agents and methods
CA2451266A1 (en) *	2001-06-21	2003-01-03	Beth Israel Deaconess Medical Center Inc.	Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
GB0125222D0 (en) *	2001-10-19	2001-12-12	Barts & London Nhs Trust	Composition for the treatment of microbial infections
EP1476168A2 (en) *	2002-02-04	2004-11-17	ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda.	Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US20080026984A1 (en) *	2002-02-04	2008-01-31	Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda	Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US7968605B2 (en) *	2002-02-04	2011-06-28	ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda.	Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
MXPA04007896A (es) *	2002-02-13	2005-06-17	Beth Israel Hospital	Metodos para tratar enfermedades vasculares.
AU2003226366A1 (en)	2002-04-15	2003-11-03	Beth Israel Deaconess Medical Center	Use of heme oxygenase-1 and products of heme degradation
MXPA04010242A (es) *	2002-04-15	2005-06-08	Univ Pittsburgh	Metodos para tratar enterocolitis necrotizante.
JP4588325B2 (ja) *	2002-04-15	2010-12-01	ユニバーシティオブピッツバーグオブザコモンウェルスシステムオブハイヤーエデュケイション	イレウスの治療方法
DK1505990T3 (da) *	2002-05-17	2011-11-21	Univ Yale	Fremgangsmåder til behandling af hepatitis
MXPA04012167A (es) *	2002-06-05	2005-09-21	Univ Yale	Metodos para tratar angiogenesis, crecimeinto tumoral y metastasis.
PL375161A1 (en) *	2002-06-21	2005-11-28	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
US7531133B2 (en) *	2002-09-10	2009-05-12	Pulmonox Technologies Corporation	Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
CN1719975A (zh) *	2002-11-07	2006-01-11	联邦高等教育系统匹兹堡大学	出血性休克的治疗
GB2395432B (en) *	2002-11-20	2005-09-14	Northwick Park Inst For Medica	Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US9675637B2 (en) *	2003-07-09	2017-06-13	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Use of nitrite salts for the treatment of cardiovascular conditions
WO2005077005A2 (en) *	2004-02-04	2005-08-25	The General Hospital Corporation	Enhancing the effectiveness of an inhaled therapeutic gas
WO2005110441A2 (en) *	2004-05-11	2005-11-24	Sensormedics Corporation	Intermittent dosing of nitric oxide gas
US8518457B2 (en) *	2004-05-11	2013-08-27	Pulmonox Technologies Corporation	Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) *	2004-07-09	2008-04-22	Huan-Cheng Lien	Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) *	2004-09-29	2007-07-05	Miller Christopher C	Use of nitric oxide in the treatment and disinfection of biofilms
WO2006125123A2 (en) *	2005-05-19	2006-11-23	University Of Cincinnati	Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
US8893717B2 (en)	2005-09-21	2014-11-25	Ino Therapeutics Llc	Systems and methods of administering a pharmaceutical gas to a patient
US7523752B2 (en)	2005-09-21	2009-04-28	Ino Therapeutics, Llc	System and method of administering a pharmaceutical gas to a patient
US20070116785A1 (en) *	2005-11-18	2007-05-24	Miller Christopher C	Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
WO2007073226A1 (en) *	2005-12-20	2007-06-28	Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda	Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en)	2006-01-24	2006-03-01	Hemocorm Ltd	Therapeutic delivery of carbon monoxide
US8079998B2 (en) *	2006-10-20	2011-12-20	Pulmonox Technologies Corporation	Methods and devices for the delivery of therapeutic gases including nitric oxide
CL2007003193A1 (es) *	2006-11-07	2008-07-04	Gen Hospital Corp	Metodo para evitar o reducir la vasoconstriccion a continuacion de la administracion de un portador de oxigeno vasoactivo, que comprende oxido nitrico gaseoso y otro agente activo; composicion farmaceutica que comprende un inhibidor de fosfodiesteras
US20080193566A1 (en) *	2007-02-09	2008-08-14	Miller Christopher C	Use of high dose concentrations of gaseous nitric oxide
CA2710349A1 (en) *	2007-12-27	2009-07-09	Aires Pharmaceuticals, Inc.	Aerosolized nitrite and nitric oxide -donating compounds and uses thereof
MX2011012467A (es)	2009-05-27	2012-01-31	Ino Therapeutics Llc	Dispositivos y metodos para engranar un montaje de valvula indexada y deposito presurizado con un zuncho, y para el accionamiento lineal mediante un montaje de embolo en comunicacion fluida con un dispsoitivo para regular la administracion de farmacos.
CA3130908A1 (en)	2009-06-30	2010-12-30	Mallinckrodt Hospital Products IP Limited	Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US20120201906A1 (en) *	2009-09-08	2012-08-09	Reynolds James D	Novel medical uses for no and no donor compounds
US9163044B2 (en)	2011-04-19	2015-10-20	Alfama, Inc.	Carbon monoxide releasing molecules and uses thereof
EP2734235B1 (en)	2011-07-21	2017-03-22	Alfama, Inc.	Ruthenium carbon monoxide releasing molecules and uses thereof
WO2013052548A2 (en)	2011-10-03	2013-04-11	Nitric Generation Technologies Llc	Apparatus and method for generating nitric oxide in controlled and accurate amounts
WO2013070592A1 (en) *	2011-11-07	2013-05-16	The General Hospital Corporation	Treatment of red blood cells
CN104411317A (zh)	2012-03-15	2015-03-11	Ino治疗有限责任公司	用于施用高浓度一氧化碳的方法
WO2019173283A1 (en)	2018-03-05	2019-09-12	Marquette University	Method and apparatus for non-invasive hemoglobin level prediction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4954526A (en) *	1989-02-28	1990-09-04	The United States Of America As Represented By The Department Of Health And Human Services	Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5380945A (en) *	1989-06-21	1995-01-10	Abbott Laboratories	Guanidino compounds as regulators of nitric oxide synthase
US5155137A (en) *	1990-09-20	1992-10-13	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Complexes of nitric oxide with polyamines
DE69127756T2 (de) *	1990-12-05	1998-02-05	The General Hospital Corp., Charlestown, Mass.	Verwendung von no zur behandlung oder prävention der bronchokonstriktion
CA2175467A1 (en) *	1993-11-02	1995-05-11	David A. Wink, Jr.	Use of nitric oxide releasing compounds as protective agents in ischemia reperfusion injury

1997
- 1997-04-03 EP EP97920137A patent/EP0914103B1/en not_active Expired - Lifetime
- 1997-04-03 CA CA002251530A patent/CA2251530C/en not_active Expired - Fee Related
- 1997-04-03 BR BR9708601A patent/BR9708601A/pt not_active Application Discontinuation
- 1997-04-03 DK DK97920137T patent/DK0914103T3/da active
- 1997-04-03 PT PT97920137T patent/PT914103E/pt unknown
- 1997-04-03 DE DE69736230T patent/DE69736230T2/de not_active Expired - Lifetime
- 1997-04-03 AU AU24403/97A patent/AU720686B2/en not_active Ceased
- 1997-04-03 WO PCT/US1997/005633 patent/WO1997037644A1/en active IP Right Grant
- 1997-04-03 AT AT97920137T patent/ATE331505T1/de active
- 1997-04-03 CN CNB971953066A patent/CN1208053C/zh not_active Expired - Fee Related
- 1997-04-03 AP APAP/P/1998/001358A patent/AP897A/en active
- 1997-04-03 JP JP09536357A patent/JP2000510448A/ja not_active Ceased
- 1997-04-03 ES ES97920137T patent/ES2267141T3/es not_active Expired - Lifetime
- 1997-04-04 US US08/832,913 patent/US5885621A/en not_active Expired - Lifetime
1998
- 1998-10-02 OA OA9800189A patent/OA10893A/en unknown

Also Published As

Publication number	Publication date
CA2251530A1 (en)	1997-10-16
AP897A (en)	2000-11-17
AU720686B2 (en)	2000-06-08
EP0914103B1 (en)	2006-06-28
EP0914103A1 (en)	1999-05-12
DE69736230D1 (de)	2006-08-10
WO1997037644A1 (en)	1997-10-16
CN1208053C (zh)	2005-06-29
EP0914103A4 (en)	2003-09-03
JP2000510448A (ja)	2000-08-15
ES2267141T3 (es)	2007-03-01
AP9801358A0 (en)	1998-12-31
US5885621A (en)	1999-03-23
DE69736230T2 (de)	2007-05-31
AU2440397A (en)	1997-10-29
OA10893A (en)	2001-10-11
CA2251530C (en)	2002-11-19
PT914103E (pt)	2006-09-29
DK0914103T3 (da)	2006-10-23
CN1227485A (zh)	1999-09-01
ATE331505T1 (de)	2006-07-15

Publication	Publication Date	Title
PT914103E (pt)	2006-09-29	Tratamento de uma hemoglobinopatia
NO983266D0 (no)	1998-07-15	Distribuert Behandling
PT777975E (pt)	2003-09-30	Tratamento de vegetais
DE69635311D1 (de)	2006-03-02	Elektrochirugische gewebeentfernung
DE59507573D1 (de)	2000-02-10	Implantat
DE59710859D1 (de)	2003-11-20	Implantat
NO983284D0 (no)	1998-07-16	Antikoagolante midler egnet i behandling av trombose
DK0959801T3 (da)	2004-01-26	Skruegevindimplantat
DK0866843T3 (da)	2001-11-19	Desodoriseringsanlæg
NO983263L (no)	1998-07-15	Distribuert behandling
IS4789A (is)	1998-06-30	Meðferðarefnasambönd
KR980000801U (ko)	1998-03-30	경혈 지압구
ID19542A (id)	1998-07-23	Pengobatan baru
BR9706702A (pt)	1999-07-20	Purificação de 1,1,1,3,3-pentafluorpropano
BR9610382A (pt)	1999-07-06	Composição de tratamento do cableo
IT1282786B1 (it)	1998-03-31	Caviglia autoperforante
ID16924A (id)	1997-11-20	Metode perlakuan poliolefin
NO972232D0 (no)	1997-05-15	Vannbehandlingssammensetninger
NO984906D0 (no)	1998-10-21	Vannbehandling
ITMI950222A0 (it)	1995-02-08	Tessuto
PT796559E (pt)	2002-11-29	Uma nova combinacao de enzimas
KR960014504U (ko)	1996-05-17	하수 처리용 원심 분리기
KR970051795U (ko)	1997-09-08	둔치-자연공법-하수처리장
PT9043T (pt)	1995-03-31	Complemento de autoclismo
BR7601137U (pt)	1998-07-14	Bone

Legal Events

Date	Code	Title	Description
2003-01-07	EG	Technical examination (opinion): publication of technical examination (opinion)
2004-07-06	B06G	Technical and formal requirements: other requirements [chapter 6.7 patent gazette]	Free format text: SUSPENSAO DO ANDAMENTO DO PEDIDO DE PATENTE PARA QUE SEJA COMPLEMENTADA A RETRIBUICAO EQUIVALENTE AO PEDIDO DE EXAME DE 87 (OITENTA E SETE) REIVINDICACOES, VISTO QUE A RETRIBUICAO PAGA ATRAVES DA PETICAO N? RJ011302, DE 20000403, REFERE-SE A 52 (CINQ?ENTA E DUAS) REIVINDICACOES.
2007-08-28	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2008-08-12	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2009-02-10	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2009-10-13	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM O ART. 10 (VIII) DA LPI.
2010-03-23	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.