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DK0826696T3 - Anvendelse af bi- og trispecifikke antistoffer til inducering af en tumorimmunitet - Google Patents

Anvendelse af bi- og trispecifikke antistoffer til inducering af en tumorimmunitet

Info

Publication number
DK0826696T3
DK0826696T3 DK97115190T DK97115190T DK0826696T3 DK 0826696 T3 DK0826696 T3 DK 0826696T3 DK 97115190 T DK97115190 T DK 97115190T DK 97115190 T DK97115190 T DK 97115190T DK 0826696 T3 DK0826696 T3 DK 0826696T3
Authority
DK
Denmark
Prior art keywords
cells
tri
tumour
activation
bind
Prior art date
Application number
DK97115190T
Other languages
English (en)
Inventor
Horst Dr Lindhofer
Hans-Jochem Prof-Dr Kolb
Stefan Prof-Dr Thierfelder
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19710497A external-priority patent/DE19710497C2/de
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Application granted granted Critical
Publication of DK0826696T3 publication Critical patent/DK0826696T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK97115190T 1996-09-03 1997-09-02 Anvendelse af bi- og trispecifikke antistoffer til inducering af en tumorimmunitet DK0826696T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19635743 1996-09-03
DE19648976 1996-11-26
DE19710497A DE19710497C2 (de) 1996-09-03 1997-03-13 Verwendung Bi- und trispezifische Antikörper zur Induktion einer Tumorimmunität

Publications (1)

Publication Number Publication Date
DK0826696T3 true DK0826696T3 (da) 2002-09-23

Family

ID=27216603

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97115190T DK0826696T3 (da) 1996-09-03 1997-09-02 Anvendelse af bi- og trispecifikke antistoffer til inducering af en tumorimmunitet

Country Status (6)

Country Link
US (1) US6551592B2 (da)
EP (1) EP0826696B1 (da)
JP (1) JP3442265B2 (da)
AT (1) ATE218143T1 (da)
DK (1) DK0826696T3 (da)
ES (1) ES2176574T3 (da)

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Also Published As

Publication number Publication date
US6551592B2 (en) 2003-04-22
JPH10182487A (ja) 1998-07-07
US20020051780A1 (en) 2002-05-02
ATE218143T1 (de) 2002-06-15
EP0826696B1 (de) 2002-05-29
EP0826696A1 (de) 1998-03-04
ES2176574T3 (es) 2002-12-01
JP3442265B2 (ja) 2003-09-02

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