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DK0815860T3 - Terfenadincarboxylat og behandlingen af allergiske lidelser - Google Patents

Terfenadincarboxylat og behandlingen af allergiske lidelser

Info

Publication number
DK0815860T3
DK0815860T3 DK97104837T DK97104837T DK0815860T3 DK 0815860 T3 DK0815860 T3 DK 0815860T3 DK 97104837 T DK97104837 T DK 97104837T DK 97104837 T DK97104837 T DK 97104837T DK 0815860 T3 DK0815860 T3 DK 0815860T3
Authority
DK
Denmark
Prior art keywords
treatment
allergic disorders
compound
formula
terfenadine carboxylate
Prior art date
Application number
DK97104837T
Other languages
English (en)
Inventor
James W Young
Raymond L Woosley
Nancy M Gray
Yiwang Chen
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0815860(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of DK0815860T3 publication Critical patent/DK0815860T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97104837T 1992-08-03 1993-08-03 Terfenadincarboxylat og behandlingen af allergiske lidelser DK0815860T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92415692A 1992-08-03 1992-08-03
US92418292A 1992-08-03 1992-08-03
EP93918584A EP0701443B2 (en) 1992-08-03 1993-08-03 Terfenadine metabolites and their optically pure isomers for treating allergic disorders

Publications (1)

Publication Number Publication Date
DK0815860T3 true DK0815860T3 (da) 2006-08-14

Family

ID=27129882

Family Applications (3)

Application Number Title Priority Date Filing Date
DK97104837T DK0815860T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandlingen af allergiske lidelser
DK02006356T DK1214937T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandling af hudirritation
DK93918584T DK0701443T4 (da) 1992-08-03 1993-08-03 Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK02006356T DK1214937T3 (da) 1992-08-03 1993-08-03 Terfenadincarboxylat og behandling af hudirritation
DK93918584T DK0701443T4 (da) 1992-08-03 1993-08-03 Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser

Country Status (24)

Country Link
US (1) US5375693A (da)
EP (4) EP1214937B1 (da)
JP (6) JP3041954B2 (da)
KR (1) KR950702420A (da)
AT (3) ATE162399T1 (da)
AU (3) AU675240B2 (da)
BR (1) BR9306841A (da)
CA (1) CA2141572C (da)
CZ (1) CZ27495A3 (da)
DE (5) DE69334145T2 (da)
DK (3) DK0815860T3 (da)
ES (3) ES2284740T3 (da)
FI (1) FI950467L (da)
GB (1) GB2284351B (da)
GR (3) GR960300024T1 (da)
HK (1) HK1045806B (da)
HU (1) HU226242B1 (da)
NO (1) NO310644B1 (da)
PL (1) PL174373B1 (da)
PT (2) PT815860E (da)
RO (1) RO116043B1 (da)
RU (1) RU2167657C2 (da)
SK (1) SK12495A3 (da)
WO (1) WO1994003170A1 (da)

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WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
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EP0723958A1 (en) * 1993-06-24 1996-07-31 Albany Molecular Research, Inc. Synthesis of substantially pure terfenadine derivatives
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US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
EP0766668B1 (en) * 1994-05-18 2002-07-17 Aventis Pharmaceuticals Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
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US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
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US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
UA60335C2 (uk) * 1997-08-26 2003-10-15 Хехст Маріон Рассел, Інк. Фармацевтична композиція, яка об'єднує піперидиноалканол з протинабряковим агентом
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
SK13822003A3 (sk) * 2001-04-09 2004-09-08 Teva Pharmaceutical Industries Ltd. Polymorfné formy chloridu fexofenadínu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
US20040044038A1 (en) * 2002-06-10 2004-03-04 Barnaba Krochmal Polymorphic form XVI of fexofenadine hydrochloride
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
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JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
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US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
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EP3973957A1 (en) 2015-03-26 2022-03-30 Sen-Jam Pharmaceutical LLC Methods and compositions to inhibit symptoms associated with veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

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WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
KR950702420A (ko) * 1992-08-03 1995-07-29 데이비드 사무소 웰 알레르기 질환 치료를 위한 테르페나딘 대사물과 그것의 광학 순수 이성체(terfenadine metabolites and their optically pure isomers for treating allergic disorders)
EP0723958A1 (en) * 1993-06-24 1996-07-31 Albany Molecular Research, Inc. Synthesis of substantially pure terfenadine derivatives
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Also Published As

Publication number Publication date
ES2086270T5 (es) 2001-02-01
EP1688142A1 (en) 2006-08-09
BR9306841A (pt) 1998-12-08
CA2141572A1 (en) 1994-02-17
AU4798693A (en) 1994-03-03
JPH08500348A (ja) 1996-01-16
GR3035417T3 (en) 2001-05-31
PL174373B1 (pl) 1998-07-31
GB2284351A (en) 1995-06-07
FI950467A0 (fi) 1995-02-02
DE9320925U1 (de) 1995-08-31
HU226242B1 (en) 2008-07-28
GR3026530T3 (en) 1998-07-31
AU675240B2 (en) 1997-01-30
AU1842999A (en) 1999-04-29
DE69334008D1 (de) 2006-05-24
GR960300024T1 (en) 1996-05-31
JP2000086512A (ja) 2000-03-28
DE69334145T2 (de) 2008-01-24
EP1214937A2 (en) 2002-06-19
JP2000086516A (ja) 2000-03-28
HK1045806B (zh) 2008-03-14
EP1214937B1 (en) 2007-05-30
NO310644B1 (no) 2001-08-06
KR950702420A (ko) 1995-07-29
PT815860E (pt) 2006-08-31
NO950374L (no) 1995-03-29
EP0815860A3 (en) 1998-01-14
DE69334145D1 (de) 2007-07-12
RO116043B1 (ro) 2000-10-30
DK1214937T3 (da) 2007-09-17
NO950374D0 (no) 1995-02-01
ATE363283T1 (de) 2007-06-15
ES2284740T3 (es) 2007-11-16
DK0701443T3 (da) 1998-02-09
JP3288660B2 (ja) 2002-06-04
EP0815860B1 (en) 2006-04-12
JP3037697B2 (ja) 2000-04-24
JP3288661B2 (ja) 2002-06-04
EP1214937A3 (en) 2002-10-30
US5375693A (en) 1994-12-27
HU9500313D0 (en) 1995-03-28
EP0701443A1 (en) 1996-03-20
DE69334008T2 (de) 2006-10-19
DE69316660T3 (de) 2001-04-05
EP0701443B1 (en) 1998-01-21
SK12495A3 (en) 1997-01-08
DE701443T1 (de) 1997-01-30
ES2257757T3 (es) 2006-08-01
DE69316660T2 (de) 1998-05-07
PT1214937E (pt) 2007-07-25
RU95107881A (ru) 1996-11-27
AU7182296A (en) 1997-01-30
EP0701443B2 (en) 2000-11-22
JP2000086514A (ja) 2000-03-28
GB9502183D0 (en) 1995-03-22
ATE322899T1 (de) 2006-04-15
JP2000086515A (ja) 2000-03-28
WO1994003170A1 (en) 1994-02-17
JP3041954B2 (ja) 2000-05-15
DK0701443T4 (da) 2000-12-18
ATE162399T1 (de) 1998-02-15
CZ27495A3 (en) 1996-09-11
ES2086270T1 (es) 1996-07-01
PL307339A1 (en) 1995-05-15
HK1045806A1 (en) 2002-12-13
CA2141572C (en) 2001-02-06
GB2284351B (en) 1996-11-27
RU2167657C2 (ru) 2001-05-27
JP2000086513A (ja) 2000-03-28
HUT71889A (en) 1996-02-28
ES2086270T3 (es) 1998-03-01
FI950467L (fi) 1995-03-31
JP3288662B2 (ja) 2002-06-04
EP0815860A2 (en) 1998-01-07
DE69316660D1 (de) 1998-02-26

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