DK0801571T3 - Opløselige 2'-chlor-2'-deoxyadenosion-formuleringer - Google Patents

Opløselige 2'-chlor-2'-deoxyadenosion-formuleringer

Info

Publication number: DK0801571T3
Authority: DK; Denmark
Prior art keywords: formulations; deoxyadenosion; chloro; soluble; cda
Prior art date: 1994-12-22

Application number

DK95943134T

Other languages

Danish (da)

English (en)

Inventor

Michael Bornstein

Rosemary Rozman

Kevin Francis Long

George Kaon Wong

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-22

Filing date

1995-12-15

Publication date

2003-01-06

1995-12-15 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

2003-01-06 Application granted granted Critical

2003-01-06 Publication of DK0801571T3 publication Critical patent/DK0801571T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK95943134T 1994-12-22 1995-12-15 Opløselige 2'-chlor-2'-deoxyadenosion-formuleringer DK0801571T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36208394A	1994-12-22	1994-12-22
PCT/US1995/016418 WO1996019230A1 (en)	1994-12-22	1995-12-15	Soluble 2-chloro-2'-deoxyadenosine formulations

Publications (1)

Publication Number	Publication Date
DK0801571T3 true DK0801571T3 (da)	2003-01-06

Family

ID=23424634

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95943134T DK0801571T3 (da)	1994-12-22	1995-12-15	Opløselige 2'-chlor-2'-deoxyadenosion-formuleringer

Country Status (15)

Country	Link
US (1)	US5681822A (pt)
EP (1)	EP0801571B1 (pt)
JP (1)	JPH10512549A (pt)
AT (1)	ATE223221T1 (pt)
CA (1)	CA2208484C (pt)
CZ (1)	CZ194297A3 (pt)
DE (1)	DE69528080T2 (pt)
DK (1)	DK0801571T3 (pt)
ES (1)	ES2182920T3 (pt)
HU (1)	HUT77928A (pt)
IL (1)	IL116469A0 (pt)
PL (1)	PL321431A1 (pt)
PT (1)	PT801571E (pt)
WO (1)	WO1996019230A1 (pt)
ZA (1)	ZA9510924B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030166525A1 (en) *	1998-07-23	2003-09-04	Hoffmann James Arthur	FSH Formulation
US6194395B1 (en) *	1999-02-25	2001-02-27	Orthro-Mcneil Pharmaceutical, Inc.	Cyclodextrin cladribine formulations
KR101105486B1 (ko) *	2003-04-02	2012-01-13	아레스 트레이딩 에스.에이.	Ｆｓｈ 및 ｌｈ과 비이온성 계면활성제의 액상 약제학적 제제
EP1638595B1 (en) *	2003-06-20	2013-03-20	Ares Trading S.A.	Freeze-dried fsh / lh formulations
FR2873695A1 (fr) *	2004-07-30	2006-02-03	Palumed Sa	Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien
WO2006067141A1 (en)	2004-12-22	2006-06-29	Laboratoires Serono S.A.	Cladribine regimen for treating multiple sclerosis
KR20090019810A (ko)	2006-05-24	2009-02-25	라보라뚜와르 세로노 에스. 에이.	다발성 경화증 치료를 위한 클라드리빈 요법
EP2343074A1 (en)	2009-12-23	2011-07-13	Merck Serono S.A.	Use of purine analogues for treating airway diseases
KR102743999B1 (ko)	2017-11-24	2024-12-17	메르크 파텐트 게엠베하	진행 형태의 다발성 경화증의 치료에서 사용을 위한 클라드리빈 용법
MX2023002843A (es)	2020-09-10	2023-03-31	Merck Patent Gmbh	Nuevo regimen de tratamiento para el tratamiento de trastornos autoinmunitarios.
AU2022231384A1 (en)	2021-03-03	2023-09-14	Ares Trading S.A.	Improved treatment methods using dmds for the treatment of autoimmune diseases, and biomarker for predicting and/or optimising said treatment methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4826823A (en) *	1985-02-05	1989-05-02	Warner-Lambert Company	Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts
US4719295A (en) *	1985-12-31	1988-01-12	Warner-Lambert Company	Compound 2-iodo-2'-deoxyadenosine
US5310732A (en) *	1986-02-03	1994-05-10	The Scripps Research Institute	2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US4908441A (en) *	1988-07-19	1990-03-13	Warner-Lambert Company	Deoxyadenosine compounds and methods of making and using the same
US5208327A (en) *	1991-12-18	1993-05-04	Ortho Pharmaceutical Corporation	Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
CA2136226C (en) *	1992-05-19	2000-05-16	Ernest Beutler	Use of 2-halo adenine derivatives as therapeutic agents against chronic myelogenous leukemia

1995
- 1995-12-15 ES ES95943134T patent/ES2182920T3/es not_active Expired - Lifetime
- 1995-12-15 CA CA002208484A patent/CA2208484C/en not_active Expired - Lifetime
- 1995-12-15 PT PT95943134T patent/PT801571E/pt unknown
- 1995-12-15 EP EP95943134A patent/EP0801571B1/en not_active Expired - Lifetime
- 1995-12-15 WO PCT/US1995/016418 patent/WO1996019230A1/en active IP Right Grant
- 1995-12-15 PL PL95321431A patent/PL321431A1/xx unknown
- 1995-12-15 DE DE69528080T patent/DE69528080T2/de not_active Expired - Lifetime
- 1995-12-15 CZ CZ971942A patent/CZ194297A3/cs unknown
- 1995-12-15 AT AT95943134T patent/ATE223221T1/de active
- 1995-12-15 JP JP8519914A patent/JPH10512549A/ja active Pending
- 1995-12-15 DK DK95943134T patent/DK0801571T3/da active
- 1995-12-15 HU HU9801007A patent/HUT77928A/hu unknown
- 1995-12-20 IL IL11646995A patent/IL116469A0/xx unknown
- 1995-12-21 ZA ZA9510924A patent/ZA9510924B/xx unknown
1997
- 1997-01-10 US US08/781,438 patent/US5681822A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2208484A1 (en)	1996-06-27
ATE223221T1 (de)	2002-09-15
ES2182920T3 (es)	2003-03-16
DE69528080T2 (de)	2003-06-05
HUT77928A (hu)	1998-11-30
IL116469A0 (en)	1996-03-31
WO1996019230A1 (en)	1996-06-27
DE69528080D1 (de)	2002-10-10
CZ194297A3 (en)	1997-10-15
ZA9510924B (en)	1997-06-23
US5681822A (en)	1997-10-28
PT801571E (pt)	2002-12-31
EP0801571B1 (en)	2002-09-04
EP0801571A1 (en)	1997-10-22
PL321431A1 (en)	1997-12-08
CA2208484C (en)	2008-09-23
JPH10512549A (ja)	1998-12-02

Publication	Publication Date	Title
HK1026363A1 (en)	2000-12-15	Ophthalmic compositions including glycerin and propylene glycol
PT799046E (pt)	2002-10-31	Solucoes estaveis de 2-cloro-2'-desoxiadenosina
LV10907A (lv)	1995-12-20	Interferona polietilenglikola atvasinajums
TR199700358A2 (xx)	1997-12-21	�nterferon birle�imler.
MY131095A (en)	2007-07-31	Polyethylene protein conjugates.
ATE257014T1 (de)	2004-01-15	Lichtbilderzeugungskontrastmitteln
BR9713866A (pt)	2000-03-14	Composição farmacéutica
FI972514A0 (fi)	1997-06-13	Kasvainspesifisten sytotoksisten T-solujen in vivo aktivointi
NO993028L (no)	1999-06-18	Vannbaserte alkoholhydroksykarboksylperoksid-sammensetninger, fremstilling og anvendelse herav
PT932397E (pt)	2006-07-31	Formulacoes em aerossol medicinais compreendendo budesonida
TR199600499A2 (tr)	1996-12-21	S(+)-Etodolak'in oral formülasyonlari.
DK0801571T3 (da)	2003-01-06	Opløselige 2'-chlor-2'-deoxyadenosion-formuleringer
DZ1926A1 (fr)	2002-02-17	Formulations pharmaceutiques.
JO1907B1 (en)	1997-01-15	Dissolved compounds of 2-chloro-2-dioxin adenosine
JO1908B1 (en)	1997-01-15	Static compounds of 2-chloro-2-dioxin adenosine
IT1254452B (it)	1995-09-25	N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
DE69822098D1 (de)	2004-04-08	Sonnenschutzmittel die beschädigte rns fragmente enthälten
CA2208241A1 (en)	1996-06-27	Stable solutions of 2-chloro-2'-deoxyadenosine formulations
McPhee	1997	The voices of young people: Being heard in our high schools
TR199701011A2 (xx)	1998-04-21	1-karba-(detia)-sefalosforin t�revleri.
RU96103721A (ru)	1998-05-10	Антгельминтное средство
MA22854A1 (fr)	1993-12-31	Conjugues de proteine et de polyethylene glycol .
KR970056462U (ko)	1997-11-10	앞.뒤로 신을 수 있는 슬리퍼
IT1288577B1 (it)	1998-09-23	Struttura di supporto, in particolare composita da attacchi per monosci
ES1036308Y (es)	1998-01-01	Telefono movil integrado en el frontal extraible del auto-radio.