DK0793714T3 - Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler - Google Patents
Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle cellerInfo
- Publication number
- DK0793714T3 DK0793714T3 DK95942865T DK95942865T DK0793714T3 DK 0793714 T3 DK0793714 T3 DK 0793714T3 DK 95942865 T DK95942865 T DK 95942865T DK 95942865 T DK95942865 T DK 95942865T DK 0793714 T3 DK0793714 T3 DK 0793714T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor
- stem cell
- cell factor
- hematopoietic
- soluble interleukin
- Prior art date
Links
- 102000010781 Interleukin-6 Receptors Human genes 0.000 title abstract 2
- 108010038501 Interleukin-6 Receptors Proteins 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 title abstract 2
- 230000003394 haemopoietic effect Effects 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 102000004889 Interleukin-6 Human genes 0.000 abstract 1
- 108090001005 Interleukin-6 Proteins 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 229940100601 interleukin-6 Drugs 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/340,559 US5610056A (en) | 1994-11-16 | 1994-11-16 | Use of stem cell factor interleukin-6 and soluble interleukin-6 receptor to induce the development of hematopoietic stem cells |
| US39314695A | 1995-02-21 | 1995-02-21 | |
| PCT/US1995/014999 WO1996015230A2 (en) | 1994-11-16 | 1995-11-16 | Use of stem cell factor and soluble interleukin-6 receptor for the ex vivo expansion of hematopoietic multipotential cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0793714T3 true DK0793714T3 (da) | 2002-09-02 |
Family
ID=26992162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95942865T DK0793714T3 (da) | 1994-11-16 | 1995-11-16 | Anvendelse af stamcellefaktor og opløselig interleukin-6-receptor til ex vivo ekspansion af hæmatopoietiske multipotentielle celler |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5861315A (da) |
| EP (1) | EP0793714B1 (da) |
| JP (1) | JP3600244B2 (da) |
| CN (1) | CN1170926C (da) |
| AT (1) | ATE221118T1 (da) |
| AU (1) | AU699479B2 (da) |
| CA (1) | CA2198603C (da) |
| DE (1) | DE69527540T2 (da) |
| DK (1) | DK0793714T3 (da) |
| ES (1) | ES2180665T3 (da) |
| MX (1) | MX9701512A (da) |
| PT (1) | PT793714E (da) |
| WO (1) | WO1996015230A2 (da) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7078224B1 (en) * | 1999-05-14 | 2006-07-18 | Promega Corporation | Cell concentration and lysate clearance using paramagnetic particles |
| JP2004502401A (ja) * | 1998-09-18 | 2004-01-29 | マサチューセッツ インスティテュート オブ テクノロジー | 哺乳動物細胞の展開及びティシュエンジニアリングのための成長因子及びホルモンの使用 |
| US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| ES2522890T3 (es) * | 2000-12-06 | 2014-11-19 | Anthrogenesis Corporation | Método para recolectar células troncales placentarias |
| EP2316918B1 (en) | 2001-02-14 | 2015-07-01 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| AU2002243980B2 (en) | 2001-02-14 | 2007-08-23 | Robert J. Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| JP2004526449A (ja) * | 2001-03-29 | 2004-09-02 | イクシオン・バイオテクノロジー・インコーポレーテッド | 非膵性幹細胞の膵分化経路への分化転換法 |
| WO2003014336A1 (fr) * | 2001-08-07 | 2003-02-20 | Kirin Beer Kabushiki Kaisha | Procede de preparation de cellules souches hematopoietiques multipotentes |
| ATE438708T1 (de) * | 2001-11-15 | 2009-08-15 | Childrens Medical Center | Verfahren zur isolierung, expansion und differenzierung fötaler stammzellen aus chorionzotte, fruchtwasser und plazenta und therapeutische verwendungen davon |
| JP2005517402A (ja) * | 2002-02-13 | 2005-06-16 | アンスロジェネシス コーポレーション | 分娩後の哺乳動物胎盤由来の胚様幹細胞、ならびに該細胞の用途および該細胞を用いる治療法 |
| WO2003080806A2 (en) * | 2002-03-18 | 2003-10-02 | National Jewish Medical And Research Center | Method for production of neutrophils and uses therefor |
| US20040161419A1 (en) * | 2002-04-19 | 2004-08-19 | Strom Stephen C. | Placental stem cells and uses thereof |
| EP1497435A4 (en) * | 2002-04-19 | 2005-07-27 | Univ Pittsburgh | PLACENTAL STEM CELLS AND USES |
| US20040044300A1 (en) * | 2002-09-03 | 2004-03-04 | Donnie Rudd | Method of replenishing cells damaged by treatment for cancer |
| US20040043009A1 (en) * | 2002-09-03 | 2004-03-04 | Donnie Rudd | Method of repairing primate mammalian tissue |
| US20040077985A1 (en) * | 2002-09-03 | 2004-04-22 | Donnie Rudd | Method of replenishing cells damaged by treatment for cancer |
| US20040076620A1 (en) * | 2002-09-03 | 2004-04-22 | Donnie Rudd | Method of repairing primate mammalian tissue |
| US20040042997A1 (en) * | 2002-09-03 | 2004-03-04 | Donnie Rudd | Method of regenerating human tissue |
| US20040076605A1 (en) * | 2002-09-03 | 2004-04-22 | Donnie Rudd | Method of regenerating human tissue |
| EP1400587A1 (en) * | 2002-09-19 | 2004-03-24 | MainGen Biotechnologie GmbH | Use of a fusion polypeptide for obtaining pluripotent non-embryonic stem cells |
| AU2003295444A1 (en) * | 2002-11-15 | 2004-06-15 | The Board Of Trustees Of The University Of Illinois | Methods for in vitro expansion of hematopoietic stem cells |
| AU2003298775B2 (en) * | 2002-11-26 | 2008-07-17 | Anthrogenesis Corporation | Cytotherapeutics, cytotherapeutic units and methods for treatments using them |
| MXPA05008445A (es) * | 2003-02-13 | 2005-10-18 | Anthrogenesis Corp | Uso de sangre del cordon umbilical para tratar individuos que tienen una enfermedad, un trastorno o una afeccion. |
| GB0321337D0 (en) * | 2003-09-11 | 2003-10-15 | Massone Mobile Advertising Sys | Method and system for distributing advertisements |
| CA2546942A1 (en) * | 2003-11-24 | 2005-06-16 | The Rockefeller University | A method for isolating a self-renewing, multipotent slow-cycling cell |
| CA2547570A1 (en) * | 2003-12-02 | 2005-06-23 | Celgene Corporation | 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione for induction of fetal hemoglobin in individuals having anemia |
| GB2432166B (en) | 2004-08-16 | 2008-01-02 | Cellres Corp Pte Ltd | Isolation of stem/progenitor cells from amniotic membrane of umbilical cord |
| WO2006093857A2 (en) * | 2005-02-28 | 2006-09-08 | Regenetech, Inc. | Method of providing readily available cellular material derived from peripheral blood and a composition thereof |
| JP2009500019A (ja) * | 2005-07-01 | 2009-01-08 | プロメガ・コーポレーション | 生体分子の精製のための浮遊性粒子のネットワーク、及び生体分子の精製のための浮遊性粒子又は浮遊性粒子のネットワークの使用 |
| EP3031909B1 (en) * | 2005-10-13 | 2021-09-15 | Celularity Inc. | Immunomodulation using placental stem cells |
| EP1963526A4 (en) | 2005-12-09 | 2009-11-18 | Promega Corp | PURIFICATION OF NUCLEIC ACID WITH A BINDING MATRIX |
| US8455250B2 (en) | 2005-12-29 | 2013-06-04 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| WO2007102814A2 (en) * | 2006-03-07 | 2007-09-13 | Regenetech, Inc. | Recombinant mammalian molecules and method for production thereof |
| EP2129775A1 (en) * | 2007-02-12 | 2009-12-09 | Anthrogenesis Corporation | Hepatocytes and chondrocytes from adherent placental stem cells; and cd34+, cd45- placental stem cell-enriched cell populations |
| EP2915537A3 (en) | 2007-02-12 | 2015-10-28 | Anthrogenesis Corporation | Treatment of inflammatory diseases using placental stem cells |
| US20100172830A1 (en) * | 2007-03-29 | 2010-07-08 | Cellx Inc. | Extraembryonic Tissue cells and method of use thereof |
| EP2155860B1 (en) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) * | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| BRPI0817751A2 (pt) | 2007-09-28 | 2017-06-13 | Anthrogenesis Corp | método para suprimir a proliferação de células de tumor, e, composição |
| EP2217329B1 (en) * | 2007-11-07 | 2018-01-10 | Anthrogenesis Corporation | Use of umbilical cord blood in the treatment of premature birth complications |
| US8222397B2 (en) * | 2009-08-28 | 2012-07-17 | Promega Corporation | Methods of optimal purification of nucleic acids and kit for use in performing such methods |
| US8039613B2 (en) | 2009-08-28 | 2011-10-18 | Promega Corporation | Methods of purifying a nucleic acid and formulation and kit for use in performing such methods |
| ES2336637B1 (es) * | 2009-11-02 | 2011-01-21 | Banc De Sang I Teixits | Procedimiento parala expansion indiferenciada u orientada a linaje mieloide de celulas madre hematopoyeticas procedentes de sangre de cordonumbilical, sangre periferica movilizada o medula osea. |
| AU2011279201B2 (en) | 2010-07-13 | 2016-01-21 | Celularity Inc. | Methods of generating natural killer cells |
| EP2625264B1 (en) | 2010-10-08 | 2022-12-07 | Terumo BCT, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| TWI602570B (zh) | 2011-06-01 | 2017-10-21 | 安瑟吉納西斯公司 | 使用胎盤幹細胞之疼痛治療 |
| WO2013055476A1 (en) | 2011-09-09 | 2013-04-18 | Anthrogenesis Corporation | Treatment of amyotrophic lateral sclerosis using placental stem cells |
| HK1218515A1 (zh) | 2013-02-05 | 2017-02-24 | 人类起源公司 | 來自胎盤的自然殺傷細胞 |
| WO2015073918A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| EP3464565A4 (en) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | CELL EXPANSION |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| EP3656841A1 (en) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| GB2619893A (en) | 2021-03-23 | 2023-12-20 | Terumo Bct Inc | Cell capture and expansion |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0639979T3 (da) * | 1992-04-23 | 2002-12-02 | Sloan Kettering Inst Cancer | Ligand for c-kit-receptoren og fremgangsmåde til anvendelse heraf |
| US5599703A (en) * | 1993-10-28 | 1997-02-04 | The United States Of America As Represented By The Secretary Of The Navy | In vitro amplification/expansion of CD34+ stem and progenitor cells |
-
1995
- 1995-11-16 CA CA002198603A patent/CA2198603C/en not_active Expired - Fee Related
- 1995-11-16 CN CNB951948687A patent/CN1170926C/zh not_active Expired - Fee Related
- 1995-11-16 AU AU44073/96A patent/AU699479B2/en not_active Ceased
- 1995-11-16 DK DK95942865T patent/DK0793714T3/da active
- 1995-11-16 ES ES95942865T patent/ES2180665T3/es not_active Expired - Lifetime
- 1995-11-16 AT AT95942865T patent/ATE221118T1/de not_active IP Right Cessation
- 1995-11-16 EP EP95942865A patent/EP0793714B1/en not_active Expired - Lifetime
- 1995-11-16 WO PCT/US1995/014999 patent/WO1996015230A2/en active IP Right Grant
- 1995-11-16 DE DE69527540T patent/DE69527540T2/de not_active Expired - Fee Related
- 1995-11-16 JP JP51635296A patent/JP3600244B2/ja not_active Expired - Fee Related
- 1995-11-16 PT PT95942865T patent/PT793714E/pt unknown
- 1995-11-16 MX MX9701512A patent/MX9701512A/es not_active IP Right Cessation
-
1996
- 1996-10-16 US US08/732,023 patent/US5861315A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5861315A (en) | 1999-01-19 |
| ES2180665T3 (es) | 2003-02-16 |
| CA2198603A1 (en) | 1996-05-23 |
| ATE221118T1 (de) | 2002-08-15 |
| PT793714E (pt) | 2002-12-31 |
| MX9701512A (es) | 1997-05-31 |
| DE69527540D1 (de) | 2002-08-29 |
| CA2198603C (en) | 2000-06-27 |
| EP0793714A2 (en) | 1997-09-10 |
| AU699479B2 (en) | 1998-12-03 |
| JPH10509040A (ja) | 1998-09-08 |
| WO1996015230A2 (en) | 1996-05-23 |
| WO1996015230A3 (en) | 1996-07-11 |
| CN1170926C (zh) | 2004-10-13 |
| JP3600244B2 (ja) | 2004-12-15 |
| EP0793714B1 (en) | 2002-07-24 |
| DE69527540T2 (de) | 2003-01-30 |
| CN1224461A (zh) | 1999-07-28 |
| AU4407396A (en) | 1996-06-06 |
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