DK0729971T3 - Fremgangsmåde til fremstilling af ivermectin - Google Patents

Fremgangsmåde til fremstilling af ivermectin

Info

Publication number: DK0729971T3
Authority: DK; Denmark
Prior art keywords: ivermectin; preparation
Prior art date: 1995-03-01

Application number

DK96102394T

Other languages

English (en)

Inventor

Dieter Prof Dr Arlt

Gerhard Dr Bonse

Friedhelm Dr Reisewitz

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-01

Filing date

1996-02-17

Publication date

2000-11-06

1996-02-17 Application filed by Bayer Ag filed Critical Bayer Ag

2000-11-06 Application granted granted Critical

2000-11-06 Publication of DK0729971T3 publication Critical patent/DK0729971T3/da

Links

AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 title 1
SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 title 1
229960002418 ivermectin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Tropical Medicine & Parasitology (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK96102394T 1995-03-01 1996-02-17 Fremgangsmåde til fremstilling af ivermectin DK0729971T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19507018A DE19507018A1 (de)	1995-03-01	1995-03-01	Verfahren zur Herstellung von Ivermectin

Publications (1)

Publication Number	Publication Date
DK0729971T3 true DK0729971T3 (da)	2000-11-06

Family

ID=7755273

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96102394T DK0729971T3 (da)	1995-03-01	1996-02-17	Fremgangsmåde til fremstilling af ivermectin

Country Status (20)

Country	Link
US (1)	US5656748A (da)
EP (1)	EP0729971B1 (da)
JP (1)	JPH09104695A (da)
KR (1)	KR100372220B1 (da)
CN (1)	CN1052236C (da)
AR (1)	AR001025A1 (da)
AT (1)	ATE196146T1 (da)
AU (1)	AU705085B2 (da)
BG (1)	BG62736B1 (da)
BR (1)	BR9600854A (da)
CA (1)	CA2170454C (da)
DE (2)	DE19507018A1 (da)
DK (1)	DK0729971T3 (da)
ES (1)	ES2151092T3 (da)
HU (1)	HU215287B (da)
PL (1)	PL183633B1 (da)
PT (1)	PT729971E (da)
SK (1)	SK281816B6 (da)
TW (1)	TW347393B (da)
ZA (1)	ZA961630B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19644050A1 (de) *	1996-10-31	1998-05-07	Bayer Ag	Verfahren zur Herstellung von Ivermectin
IT1289993B1 (it) *	1997-02-27	1998-10-19	Antibioticos Spa	Processo per la preparazione di ivermectina
US6265571B1 (en) *	1999-07-12	2001-07-24	Magellan Laboratories, Inc.	Purification process for anti-parasitic fermentation product
CN100486986C (zh) *	2007-01-29	2009-05-13	四川大学	一种依维菌素的制备方法
CN117417398B (zh) *	2023-10-10	2026-02-06	河北美荷药业有限公司	一种伊维菌素的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH15982A (en) *	1977-10-03	1983-05-18	Merck & Co Inc	Selective hydrogenation producta of c-076 compounds and derivatives thereof
PT79774A (en) *	1984-12-28	1985-01-01	Joao Emerico Villax	Process to prepare rhodium catalysts and applications thereof
US4831016A (en) *	1986-10-31	1989-05-16	Merck & Co., Inc.	Reduced avermectin derivatives
US4873224A (en) *	1988-05-23	1989-10-10	Merck & Co., Inc.	Avermectin derivatives
PT91333B (pt) *	1989-07-31	1995-05-04	Hovione Sociedade Quimica Sa	Processo para a preparacao de um complexo de rodio
KR100693669B1 (ko) *	2003-03-03	2007-03-09	엘지전자 주식회사	피일드 매크로 블록의 레퍼런스 픽쳐 결정 방법

1995
- 1995-03-01 DE DE19507018A patent/DE19507018A1/de not_active Withdrawn
1996
- 1996-02-05 TW TW085101372A patent/TW347393B/zh not_active IP Right Cessation
- 1996-02-17 DK DK96102394T patent/DK0729971T3/da active
- 1996-02-17 DE DE59605835T patent/DE59605835D1/de not_active Expired - Fee Related
- 1996-02-17 PT PT96102394T patent/PT729971E/pt unknown
- 1996-02-17 EP EP96102394A patent/EP0729971B1/de not_active Expired - Lifetime
- 1996-02-17 ES ES96102394T patent/ES2151092T3/es not_active Expired - Lifetime
- 1996-02-17 AT AT96102394T patent/ATE196146T1/de not_active IP Right Cessation
- 1996-02-22 AU AU45683/96A patent/AU705085B2/en not_active Ceased
- 1996-02-23 AR ARP960101511A patent/AR001025A1/es active IP Right Grant
- 1996-02-23 JP JP8060277A patent/JPH09104695A/ja active Pending
- 1996-02-26 KR KR1019960004675A patent/KR100372220B1/ko not_active Expired - Fee Related
- 1996-02-27 US US08/606,787 patent/US5656748A/en not_active Expired - Fee Related
- 1996-02-27 BG BG100387A patent/BG62736B1/bg unknown
- 1996-02-27 PL PL96312953A patent/PL183633B1/pl not_active IP Right Cessation
- 1996-02-27 CA CA002170454A patent/CA2170454C/en not_active Expired - Fee Related
- 1996-02-29 SK SK281-96A patent/SK281816B6/sk unknown
- 1996-02-29 ZA ZA961630A patent/ZA961630B/xx unknown
- 1996-02-29 HU HU9600499A patent/HU215287B/hu not_active IP Right Cessation
- 1996-02-29 BR BR9600854A patent/BR9600854A/pt not_active Application Discontinuation
- 1996-03-01 CN CN96102713A patent/CN1052236C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR100372220B1 (ko)	2003-07-10
SK28196A3 (en)	1996-09-04
AU4568396A (en)	1996-09-05
HUP9600499A2 (en)	1997-04-28
ES2151092T3 (es)	2000-12-16
HUP9600499A3 (en)	1997-08-28
PT729971E (pt)	2001-01-31
CA2170454C (en)	2007-04-24
AU705085B2 (en)	1999-05-13
DE59605835D1 (de)	2000-10-12
EP0729971A1 (de)	1996-09-04
ZA961630B (en)	1996-09-06
US5656748A (en)	1997-08-12
BG62736B1 (bg)	2000-06-30
TW347393B (en)	1998-12-11
HU215287B (hu)	1998-11-30
CN1052236C (zh)	2000-05-10
PL183633B1 (pl)	2002-06-28
KR960034211A (ko)	1996-10-22
CA2170454A1 (en)	1996-09-02
SK281816B6 (sk)	2001-08-06
PL312953A1 (en)	1996-09-02
ATE196146T1 (de)	2000-09-15
EP0729971B1 (de)	2000-09-06
JPH09104695A (ja)	1997-04-22
BG100387A (bg)	1996-09-30
HU9600499D0 (en)	1996-04-29
AR001025A1 (es)	1997-08-27
CN1141300A (zh)	1997-01-29
BR9600854A (pt)	1997-12-30
DE19507018A1 (de)	1996-09-05

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