DK0725637T3 - Parenteralt busulfan til behandling af malign sygdom - Google Patents
Parenteralt busulfan til behandling af malign sygdomInfo
- Publication number
- DK0725637T3 DK0725637T3 DK94929116T DK94929116T DK0725637T3 DK 0725637 T3 DK0725637 T3 DK 0725637T3 DK 94929116 T DK94929116 T DK 94929116T DK 94929116 T DK94929116 T DK 94929116T DK 0725637 T3 DK0725637 T3 DK 0725637T3
- Authority
- DK
- Denmark
- Prior art keywords
- malignant disease
- treatment
- busulfan
- parenteral
- parenteral busulfan
- Prior art date
Links
- COVZYZSDYWQREU-UHFFFAOYSA-N Busulfan Chemical compound CS(=O)(=O)OCCCCOS(C)(=O)=O COVZYZSDYWQREU-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002092 busulfan Drugs 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000003211 malignant effect Effects 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/129,995 US5430057A (en) | 1993-09-30 | 1993-09-30 | Parenteral busulfan for treatment of malignant disease |
PCT/US1994/009748 WO1995008991A1 (en) | 1993-09-30 | 1994-08-30 | Parenteral busulfan for treatment of malignant disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0725637T3 true DK0725637T3 (da) | 2001-03-26 |
Family
ID=22442547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94929116T DK0725637T3 (da) | 1993-09-30 | 1994-08-30 | Parenteralt busulfan til behandling af malign sygdom |
Country Status (13)
Country | Link |
---|---|
US (2) | US5430057A (da) |
EP (1) | EP0725637B1 (da) |
JP (1) | JP3599285B2 (da) |
KR (1) | KR100371826B1 (da) |
AT (1) | ATE197670T1 (da) |
AU (1) | AU694141B2 (da) |
CA (1) | CA2171738C (da) |
DE (1) | DE69426334T2 (da) |
DK (1) | DK0725637T3 (da) |
ES (1) | ES2153862T3 (da) |
GR (1) | GR3035447T3 (da) |
PT (1) | PT725637E (da) |
WO (1) | WO1995008991A1 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877205A (en) * | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
US6045815A (en) * | 1997-08-15 | 2000-04-04 | Board Of Regents, The University Of Texas System | Parenteral pimaricin as treatment of systemic infections |
US6844004B2 (en) | 1997-08-15 | 2005-01-18 | Board Of Regents, The University Of Texas System | Topical formulations of natamycin/pimaricin |
US6734338B1 (en) | 1997-11-14 | 2004-05-11 | Cedars-Sinai Medical Center | Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies |
US7294755B1 (en) | 1997-11-14 | 2007-11-13 | Cedars-Sinai Medical Center | Genetic modification of male germ cells for generation of transgenic species and genetic therapies |
JP2001523468A (ja) * | 1997-11-14 | 2001-11-27 | セダーシナイ メディカル センター | トランスジェニック種の産生のための雄性生殖細胞のトランスフェクションおよび移入 |
US20080131498A1 (en) * | 1998-06-18 | 2008-06-05 | Busulipo Ab | Pharmaceutical composition, a method of preparing it and a method of treatment by use thereof |
US7351427B2 (en) * | 1998-06-18 | 2008-04-01 | Busulipo Ab | Pharmaceutical composition, a method of preparing it and a method of treatment by use thereof |
JP2002518322A (ja) * | 1998-06-18 | 2002-06-25 | カロリンスカ イノベイションズ エイビー | ブスルファンのリポソーム製剤 |
HUP0303930A3 (en) * | 2001-01-26 | 2012-09-28 | Univ Emory | Methods of inducing organ transplant tolerance and correcting hemoglobinopathies |
US7122640B2 (en) * | 2002-06-10 | 2006-10-17 | Phynexus, Inc. | Open channel solid phase extraction systems and methods |
CA2488526A1 (en) * | 2002-06-26 | 2004-01-08 | Pharmacia Corporation | Stable liquid parenteral parecoxib formulation |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
MXPA06012648A (es) * | 2004-05-05 | 2007-02-14 | Celgene Corp | Metodo de utilizacion y composiciones que comprenden compuestos inmunomodulatorios para el tratamiento y manejo de enfermedades mieloproliferativas. |
EP1789791A4 (en) * | 2004-09-15 | 2010-08-04 | Saladax Biomedical Inc | Busulfan IMMUNOASSAY |
US20100322895A1 (en) * | 2007-06-20 | 2010-12-23 | University Of Louisville Research Foundation, Inc. | T cell depleting compositions useful for treating cancer |
CN102151257B (zh) * | 2011-02-17 | 2015-03-04 | 四川科瑞德凯华制药有限公司 | 一种白消安注射剂及其制备方法 |
PL2701684T3 (pl) | 2011-04-28 | 2018-09-28 | Platform Brightworks Two, Ltd. | Ulepszone preparaty pozajelitowe lipofilowych środków farmaceutycznych oraz sposoby ich wytwarzania i stosowania |
CN103446045B (zh) * | 2012-06-01 | 2015-08-12 | 四川科瑞德凯华制药有限公司 | 一种稳定的白消安注射剂 |
WO2014089957A1 (zh) * | 2012-12-11 | 2014-06-19 | 四川科瑞德凯华制药有限公司 | 一种稳定的白消安注射剂 |
CN105726467A (zh) * | 2014-12-09 | 2016-07-06 | 四川科瑞德制药有限公司 | 一种白消安注射液及其制备方法 |
CN110831588B (zh) * | 2017-05-03 | 2023-06-27 | 锡德克斯药物公司 | 包含环糊精和白消安的组合物 |
CN109078005B (zh) | 2018-08-07 | 2021-11-26 | 江苏领航生物科技有限公司 | 一种白消安组合物及其制备方法和应用 |
MA55531A (fr) * | 2019-04-02 | 2022-02-09 | Sangamo Therapeutics Inc | Procédés pour le traitement de béta-thalassémie |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3109783C2 (de) * | 1981-03-13 | 1987-04-02 | Schwarz GmbH, 4019 Monheim | Verfahren zur Herstellung einer ethanolfreien Nitroglycerinlösung mit einer Konzentration von etwa 1 mg Nitroglycerin/ml |
JPS6461429A (en) * | 1987-08-29 | 1989-03-08 | Akio Hagiwara | Remedy for cancer |
US5180716A (en) * | 1990-08-01 | 1993-01-19 | The Regents Of The University Of California | Cyclodextrin complexes for neuraxial administration of drugs |
-
1993
- 1993-09-30 US US08/129,995 patent/US5430057A/en not_active Expired - Lifetime
-
1994
- 1994-08-30 ES ES94929116T patent/ES2153862T3/es not_active Expired - Lifetime
- 1994-08-30 KR KR1019960701624A patent/KR100371826B1/ko not_active Expired - Lifetime
- 1994-08-30 AT AT94929116T patent/ATE197670T1/de active
- 1994-08-30 WO PCT/US1994/009748 patent/WO1995008991A1/en active IP Right Grant
- 1994-08-30 DE DE69426334T patent/DE69426334T2/de not_active Expired - Lifetime
- 1994-08-30 JP JP51031195A patent/JP3599285B2/ja not_active Expired - Lifetime
- 1994-08-30 DK DK94929116T patent/DK0725637T3/da active
- 1994-08-30 AU AU78290/94A patent/AU694141B2/en not_active Expired
- 1994-08-30 EP EP94929116A patent/EP0725637B1/en not_active Expired - Lifetime
- 1994-08-30 PT PT94929116T patent/PT725637E/pt unknown
- 1994-08-30 CA CA002171738A patent/CA2171738C/en not_active Expired - Lifetime
-
1995
- 1995-05-24 US US08/449,685 patent/US5559148A/en not_active Expired - Lifetime
-
2001
- 2001-02-21 GR GR20010400278T patent/GR3035447T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH09502996A (ja) | 1997-03-25 |
DE69426334D1 (de) | 2000-12-28 |
KR100371826B1 (ko) | 2003-05-09 |
AU7829094A (en) | 1995-04-18 |
CA2171738C (en) | 2002-07-16 |
KR960704543A (ko) | 1996-10-09 |
ES2153862T3 (es) | 2001-03-16 |
ATE197670T1 (de) | 2000-12-15 |
JP3599285B2 (ja) | 2004-12-08 |
US5559148A (en) | 1996-09-24 |
EP0725637A1 (en) | 1996-08-14 |
DE69426334T2 (de) | 2001-03-29 |
AU694141B2 (en) | 1998-07-16 |
PT725637E (pt) | 2001-06-29 |
EP0725637B1 (en) | 2000-11-22 |
WO1995008991A1 (en) | 1995-04-06 |
US5430057A (en) | 1995-07-04 |
GR3035447T3 (en) | 2001-05-31 |
CA2171738A1 (en) | 1995-04-06 |
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