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DK0690049T3 - Middel til behandling af hepato-biliære sygdomme - Google Patents

Middel til behandling af hepato-biliære sygdomme

Info

Publication number
DK0690049T3
DK0690049T3 DK95303718T DK95303718T DK0690049T3 DK 0690049 T3 DK0690049 T3 DK 0690049T3 DK 95303718 T DK95303718 T DK 95303718T DK 95303718 T DK95303718 T DK 95303718T DK 0690049 T3 DK0690049 T3 DK 0690049T3
Authority
DK
Denmark
Prior art keywords
treatment
agent
hepatobiliary diseases
methyl group
hepato
Prior art date
Application number
DK95303718T
Other languages
Danish (da)
English (en)
Inventor
Ryuji Ueno
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of DK0690049T3 publication Critical patent/DK0690049T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95303718T 1994-06-03 1995-05-31 Middel til behandling af hepato-biliære sygdomme DK0690049T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12248794 1994-06-03

Publications (1)

Publication Number Publication Date
DK0690049T3 true DK0690049T3 (da) 2000-03-06

Family

ID=14837070

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95303718T DK0690049T3 (da) 1994-06-03 1995-05-31 Middel til behandling af hepato-biliære sygdomme

Country Status (14)

Country Link
US (1) US5739161A (fi)
EP (1) EP0690049B1 (fi)
KR (1) KR100260573B1 (fi)
CN (1) CN1076605C (fi)
AT (1) ATE182884T1 (fi)
AU (1) AU690241B2 (fi)
CA (1) CA2150287C (fi)
DE (1) DE69511181T2 (fi)
DK (1) DK0690049T3 (fi)
ES (1) ES2137456T3 (fi)
FI (1) FI952721L (fi)
GR (1) GR3031066T3 (fi)
NO (1) NO308993B1 (fi)
NZ (1) NZ272234A (fi)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
TWI225398B (en) 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
ATE402925T2 (de) 1999-10-15 2008-08-15 Sucampo Ag Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid
CN1443070A (zh) 2000-03-24 2003-09-17 苏坎波公司 包含15－酮基－前列腺素或其衍生物的编程性细胞死亡抑制组合物
KR100874626B1 (ko) * 2000-04-06 2008-12-17 수캄포 아게 담즙 분비 촉진 조성물
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
BR0212233A (pt) 2001-08-31 2004-10-05 Sucampo Ag Abridor de canal de cloreto
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
TWI263505B (en) * 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
AU2003274735B2 (en) * 2002-10-23 2008-12-04 Sucampo Ag Prostaglandin compounds for the treatment of obesity
KR20120045051A (ko) 2002-12-27 2012-05-08 수캄포 아게 복부 불쾌감 치료용 프로스타글랜딘의 유도체
US8337891B2 (en) * 2003-07-03 2012-12-25 Sucampo Ag Enteric coated composition comprising prostaglandin analogs as chloride channel opener
KR20120005052A (ko) 2003-08-21 2012-01-13 수캄포 아게 안과용 조성물
JP4690814B2 (ja) * 2004-08-02 2011-06-01 株式会社アールテック・ウエノ プロスタグランジン誘導体の製造法
PL1841433T3 (pl) 2005-01-27 2012-07-31 Sucampo Ag Kompozycja do leczenia zaburzeń ośrodkowego układu nerwowego
ES2355518T3 (es) * 2005-03-04 2011-03-28 Sucampo Ag Procedimiento y composición para el tratamiento de enfermedades vasculares periféricas.
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
WO2006109881A1 (en) * 2005-04-12 2006-10-19 Sucampo Ag Combined use of prostaglandin compound and proton pump inhibitor for the treatment of gastrointestinal disorders
NZ570191A (en) * 2006-01-24 2010-09-30 R Tech Ueno Ltd Soft-gelatin capsule formulation comprising a keto-prostaglandin compound
KR20180027615A (ko) 2006-01-24 2018-03-14 가부시키가이샤 아루떼꾸 우에노 바이-사이클릭 화합물을 함유하는 약학적 조성물 및 바이-사이클릭 화합물의 안정화 방법
JP4648340B2 (ja) * 2006-02-07 2011-03-09 株式会社アールテック・ウエノ １５−ケトプロスタグランジンｅ誘導体の製造法
CA2819844C (en) * 2006-02-07 2015-09-15 R-Tech Ueno, Ltd. Prostaglandin derivatives
AU2007223469B2 (en) * 2006-02-28 2012-06-07 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
RU2008140298A (ru) 2006-03-13 2010-04-20 Р-Тек Уено, Лтд. (Jp) Водная композиция
US8871752B2 (en) 2008-02-19 2014-10-28 Sucampo Ag Method for modulating stem cell growth
US8609729B2 (en) 2009-04-15 2013-12-17 Sucampo Ag Method for treating macular degeneration
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
US8889735B2 (en) 2011-04-07 2014-11-18 Sucampo Ag Method for treating asthenopia
BR112013026644A2 (pt) * 2011-04-19 2016-12-27 Sucampo Ag método para a modulação da atividade de citocina
JP2014522805A (ja) * 2011-07-01 2014-09-08 株式会社アールテック・ウエノ 脂肪酸誘導体の製造法
CN102875586A (zh) * 2011-07-11 2013-01-16 上海天伟生物制药有限公司 一种利马前列素关键中间体的制备方法
WO2013022079A1 (en) 2011-08-05 2013-02-14 Sucampo Ag Method for treating schizophrenia
CN103058907B (zh) * 2011-10-21 2016-05-11 武汉启瑞药业有限公司 鲁比前列酮或其中间体的制备方法
AR092821A1 (es) 2012-04-20 2015-05-06 Sucampo Ag Conjugado de derivado de acido graso-polimero
US20150057351A1 (en) 2013-08-22 2015-02-26 Sucampo Ag Method for treating neuropathic pain
WO2016203317A1 (en) 2015-06-19 2016-12-22 Sucampo Ag Pharmaceutical compositions comprising fatty acid derivative
US10428566B2 (en) * 2017-04-17 2019-10-01 James G. Arendts Flexible unitary sandwich-like panel overhead door

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4306078A (en) * 1979-12-03 1981-12-15 Hoffmann-La Roche Inc. 16-Substituted prostaglandins
US4374856A (en) 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
JPS58164512A (ja) 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS58203911A (ja) 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS62129218A (ja) 1985-12-02 1987-06-11 Teijin Ltd チアプロスタグランジン類を活性成分として含有する肝疾患治療剤
JPH0688966B2 (ja) 1987-01-28 1994-11-09 株式会社アールテック・ウエノ プロスタグランジンｅ類およびそれを含む抗潰瘍剤
CA1323364C (en) 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
JPH0681728B2 (ja) 1987-10-02 1994-10-19 株式会社上野製薬応用研究所 下 剤
ATE78465T1 (de) 1987-10-02 1992-08-15 Ueno Seiyaku Oyo Kenkyujo Kk Kathartica.
JP2579193B2 (ja) 1988-07-19 1997-02-05 小野薬品工業株式会社 １６，１６−ジフルオロ−１５−オキソ−１５−デオキシｐｇｅ誘導体
DD295522A5 (de) * 1989-07-26 1991-11-07 �����@������������������k�� 5-Alkyl-1,3,4-Thiadiazole, Verfahren zu ihrer Herstellung und Verwendung als Schädlingsbekämpfungsmittel
CA2027814C (en) 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds

Also Published As

Publication number Publication date
NZ272234A (en) 1996-02-27
FI952721A0 (fi) 1995-06-02
NO952214D0 (no) 1995-06-02
FI952721A7 (fi) 1995-12-04
GR3031066T3 (en) 1999-12-31
CA2150287A1 (en) 1995-12-04
NO308993B1 (no) 2000-11-27
EP0690049A3 (en) 1997-03-26
EP0690049A2 (en) 1996-01-03
CN1076605C (zh) 2001-12-26
NO952214L (no) 1995-12-04
US5739161A (en) 1998-04-14
ATE182884T1 (de) 1999-08-15
CN1126591A (zh) 1996-07-17
EP0690049B1 (en) 1999-08-04
CA2150287C (en) 2004-08-10
DE69511181T2 (de) 1999-12-02
ES2137456T3 (es) 1999-12-16
AU2041295A (en) 1995-12-14
AU690241B2 (en) 1998-04-23
KR100260573B1 (ko) 2000-07-01
FI952721L (fi) 1995-12-04
KR960000230A (ko) 1996-01-25
DE69511181D1 (de) 1999-09-09

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