DE69932901D1 - Verfahren zur Isolierung und Rückgewinnung von Zellen - Google Patents
Verfahren zur Isolierung und Rückgewinnung von ZellenInfo
- Publication number
- DE69932901D1 DE69932901D1 DE69932901T DE69932901T DE69932901D1 DE 69932901 D1 DE69932901 D1 DE 69932901D1 DE 69932901 T DE69932901 T DE 69932901T DE 69932901 T DE69932901 T DE 69932901T DE 69932901 D1 DE69932901 D1 DE 69932901D1
- Authority
- DE
- Germany
- Prior art keywords
- filtering device
- isolating
- line
- recovering
- priming liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000001914 filtration Methods 0.000 abstract 6
- 239000007788 liquid Substances 0.000 abstract 4
- 230000037452 priming Effects 0.000 abstract 3
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0236—Multiple bag systems for separating or storing blood components with sampling means, e.g. sample bag or sampling port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7554—General characteristics of the apparatus with filters with means for unclogging or regenerating filters
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Water Supply & Treatment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27936498 | 1998-09-14 | ||
JP27936498A JP3517359B2 (ja) | 1998-09-14 | 1998-09-14 | 細胞分離・回収装置および細胞の分離・回収方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69932901D1 true DE69932901D1 (de) | 2006-10-05 |
DE69932901T2 DE69932901T2 (de) | 2007-03-01 |
Family
ID=17610139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69932901T Expired - Lifetime DE69932901T2 (de) | 1998-09-14 | 1999-09-13 | Verfahren zur Isolierung und Rückgewinnung von Zellen |
Country Status (5)
Country | Link |
---|---|
US (1) | US6312950B1 (de) |
EP (1) | EP0987034B1 (de) |
JP (1) | JP3517359B2 (de) |
AT (1) | ATE337035T1 (de) |
DE (1) | DE69932901T2 (de) |
Families Citing this family (70)
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US6306350B1 (en) * | 1999-05-19 | 2001-10-23 | Itt Manufacturing Enterprises, Inc. | Water sampling method and apparatus with analyte integration |
DE60131627T2 (de) * | 2000-01-14 | 2008-10-23 | Entegris, Inc., Chaska | Filtriermethode basierend auf einem neutralen verhalten des filtermaterials |
EP1573416A4 (de) * | 2000-07-07 | 2010-01-27 | Fenwal Inc | Medizinisches system, verfahren und gerät, das mems verwendet |
US7045148B2 (en) | 2000-12-06 | 2006-05-16 | Anthrogenesis Corporation | Method of collecting placental stem cells |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
EP2336300B1 (de) | 2001-02-14 | 2015-07-08 | Anthrogenesis Corporation | Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen |
FR2825261B1 (fr) * | 2001-06-01 | 2003-09-12 | Maco Pharma Sa | Ligne de prelevement du sang placentaire comprenant une poche de rincage |
US6623959B2 (en) | 2001-06-13 | 2003-09-23 | Ethicon, Inc. | Devices and methods for cell harvesting |
US7156803B2 (en) | 2002-08-19 | 2007-01-02 | Depuy Spine, Inc. | Devices for controlling fluid flow through a medium |
KR20100125479A (ko) | 2002-11-26 | 2010-11-30 | 안트로제네시스 코포레이션 | 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법 |
JP4158095B2 (ja) * | 2003-01-15 | 2008-10-01 | 株式会社クニムネ | 尿検体の採取・保存器具 |
US7601268B2 (en) * | 2003-05-27 | 2009-10-13 | Haemonetics Corporation | Continuous blood filtration and method of use |
JP2007017151A (ja) * | 2003-09-30 | 2007-01-25 | Dai Ichi Pure Chem Co Ltd | フィルターホルダーとそれを装着した検査用フィルターユニット |
NZ567335A (en) | 2005-10-13 | 2012-02-24 | Anthrogenesis Corp | Immunomodulation using placental stem cells |
PL2471903T3 (pl) | 2005-12-29 | 2018-09-28 | Anthrogenesis Corporation | Populacje komórek macierzystych łożyska |
CN101389754A (zh) | 2005-12-29 | 2009-03-18 | 人类起源公司 | 胎盘干细胞和第二来源干细胞的联合培养 |
ME01562B (me) | 2007-02-12 | 2014-09-20 | Anthrogenesis Corp | Liječenje protuupalnih bolesti putem matičnih stanica posteljice |
KR20090121297A (ko) * | 2007-03-02 | 2009-11-25 | 스미쓰 앤드 네퓨 피엘씨 | 생물학적 시료의 여과시 초음파, 역세정 및 필터 이동에 의한 필터 세정용 기기 및 방법 |
US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
MX2010003291A (es) | 2007-09-28 | 2012-02-21 | Anthrogenesis Corp | Supresion de tumores utilizando perfundido placentario humano y células destructoras naturales intermediarias derivadas de la placenta humana. |
CN105181407B (zh) | 2008-03-31 | 2020-06-30 | 希森美康株式会社 | 制样装置与制样方法以及细胞分析装置与细胞分析方法 |
JP5003614B2 (ja) * | 2008-07-03 | 2012-08-15 | 株式会社日立プラントテクノロジー | 生体細胞の分離方法及び培養装置 |
CA2734236C (en) | 2008-08-20 | 2020-08-25 | Anthrogenesis Corporation | Improved cell composition and methods of making the same |
KR20230031991A (ko) | 2008-08-20 | 2023-03-07 | 셀룰래리티 인코포레이티드 | 단리된 태반 세포를 사용한 뇌졸중 치료 |
KR20110050688A (ko) | 2008-08-22 | 2011-05-16 | 안트로제네시스 코포레이션 | 태반 세포 집단을 이용한 골 결함의 치료 방법 및 골 결함 치료 조성물 |
JP2010094266A (ja) * | 2008-10-16 | 2010-04-30 | Nipro Corp | 体外循環モジュールのプライミング用液体およびプライミング方法 |
RU2562154C2 (ru) | 2008-11-19 | 2015-09-10 | Антродженезис Корпорейшн | Амниотические адгезивные клетки |
KR101674517B1 (ko) * | 2009-06-30 | 2016-11-09 | 가부시키가이샤 가네카 | 혈액 성분의 분리 시스템, 분리재 |
NZ619359A (en) | 2009-07-02 | 2015-07-31 | Anthrogenesis Corp | Method of producing erythrocytes without feeder cells |
DE102009052671B4 (de) * | 2009-11-12 | 2015-07-30 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur Behandlung eines Filtrationsmediums |
US9121007B2 (en) | 2010-01-26 | 2015-09-01 | Anthrogenesis Corporatin | Treatment of bone-related cancers using placental stem cells |
EP2554190B1 (de) * | 2010-03-31 | 2016-02-24 | Asahi Kasei Medical Co., Ltd. | System und verfahren zur entlüftung eines leukozytenentfernungsmittels |
CN102933703A (zh) | 2010-04-07 | 2013-02-13 | 人类起源公司 | 使用胎盘干细胞的血管生成 |
KR20130092394A (ko) | 2010-04-08 | 2013-08-20 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 사르코이드증의 치료 |
NZ605505A (en) | 2010-07-13 | 2015-02-27 | Anthrogenesis Corp | Methods of generating natural killer cells |
DE102010047826A1 (de) * | 2010-10-04 | 2012-04-05 | Eppendorf Ag | Elektronische Pipette |
JP5738582B2 (ja) * | 2010-12-06 | 2015-06-24 | 株式会社カネカ | プライミング時の気泡の除去を簡便にする部材を備えた細胞溶液処理器具およびその使用方法 |
JP2012120458A (ja) * | 2010-12-06 | 2012-06-28 | Kaneka Corp | 細胞の分離器具。 |
JP2012120457A (ja) * | 2010-12-06 | 2012-06-28 | Kaneka Corp | プライミング装置機能付き細胞分離装置およびそれを用いたプライミング法。 |
WO2012092485A1 (en) | 2010-12-31 | 2012-07-05 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory rna molecules |
WO2012125457A1 (en) * | 2011-03-11 | 2012-09-20 | Fenwal, Inc. | Membrane separation devices, systems and methods employing same and data management systems and methods |
JP6104896B2 (ja) | 2011-06-01 | 2017-03-29 | アントフロゲネシス コーポレーション | 胎盤幹細胞を使用する疼痛の治療 |
JP2013034436A (ja) * | 2011-08-09 | 2013-02-21 | Kaneka Corp | 細胞懸濁液の濃縮方法 |
DE102011112291B4 (de) * | 2011-09-05 | 2015-07-09 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur Filtration einer Flüssigkeitsprobe |
WO2013055476A1 (en) | 2011-09-09 | 2013-04-18 | Anthrogenesis Corporation | Treatment of amyotrophic lateral sclerosis using placental stem cells |
WO2013102165A2 (en) * | 2011-12-29 | 2013-07-04 | Delcath Systems, Inc. | Adjustable filter apparatus |
EP2854999B1 (de) * | 2012-05-30 | 2020-04-01 | GE Healthcare Bio-Sciences AB | Filtrierungskassette und stapel aus filtrierungskassetten |
US10253295B2 (en) | 2012-09-06 | 2019-04-09 | Biomet Manufacturing, Llc | Methods for producing rejuvenated red blood cells |
US9066909B2 (en) | 2012-09-06 | 2015-06-30 | Biomet Biologics, Llc | Methods for producing and using rejuvenated red blood cells |
JP6113988B2 (ja) * | 2012-09-26 | 2017-04-12 | 旭化成株式会社 | 腹水処理システム及び複合システム |
US9011408B2 (en) * | 2013-01-31 | 2015-04-21 | Biomet Biologics, Llc | Functionally-closed, sterile blood processing solution system and method |
US9103842B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
US9102918B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
CN115282165A (zh) | 2013-02-05 | 2022-11-04 | 细胞结构公司 | 来自胎盘的自然杀伤细胞 |
JP6251998B2 (ja) * | 2013-07-05 | 2017-12-27 | 日立化成株式会社 | 細胞捕捉システム及び細胞捕捉システムの運転方法 |
JP6299115B2 (ja) * | 2013-08-29 | 2018-03-28 | 日立化成株式会社 | 細胞捕捉デバイス及び細胞捕捉システム |
US10676707B2 (en) | 2013-09-12 | 2020-06-09 | Universal Bio Research Co., Ltd. | Culture system and culture method |
WO2015037120A1 (ja) * | 2013-09-13 | 2015-03-19 | 株式会社メディネット | 細胞懸濁液ろ過器具及び細胞懸濁液を含む点滴用溶液の調製方法 |
US20150209721A1 (en) * | 2014-01-28 | 2015-07-30 | Air Products And Chemicals, Inc. | Solid-State Membrane Module |
US9067172B1 (en) * | 2014-01-28 | 2015-06-30 | Air Products And Chemicals, Inc. | Solid-state membrane module |
KR20170066512A (ko) * | 2014-10-08 | 2017-06-14 | 히타치가세이가부시끼가이샤 | 세포 포착 디바이스 |
KR101776245B1 (ko) | 2014-11-20 | 2017-09-11 | 울산과학기술원 | 입자 여과 장치 및 입자 여과 방법 |
JP6615577B2 (ja) * | 2015-10-29 | 2019-12-04 | 株式会社カネカ | 細胞分離フィルターを用いた細胞濃縮液の製造方法 |
EP3471793B1 (de) * | 2016-06-16 | 2023-12-20 | Haemonetics Corporation | Blutverarbeitungssystem mit einem y-verbinder |
DE102018004521A1 (de) * | 2018-06-07 | 2019-12-12 | Sartorius Stedim Biotech Gmbh | Serielle Anordnung mit mehreren Lagen asymmetrischer Filtermedien, Herstellungsverfahren, Filtrationseinheit, Verwendung der Anordnung und Charakterisierungsverfahren |
US11320345B2 (en) * | 2019-03-18 | 2022-05-03 | Avantor Fluid Handling, Llc | Adjustable volume sampling system (AVSS) |
CN110511860B (zh) * | 2019-09-06 | 2022-09-06 | 辽宁鼎天生命科技有限公司 | 一种用于实验室提取干细胞的一体化装置 |
DE102019215029A1 (de) * | 2019-09-30 | 2021-04-01 | Robert Bosch Gmbh | Filterabfolge, Spritzenaufsatz und Verfahren zur Separierung von Partikeln aus einer Körperflüssigkeit |
DE102020216578B4 (de) * | 2020-12-28 | 2023-02-09 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Vorrichtung und Verfahren zur Separation von unterschiedlich großen Partikeln in einer Flüssigkeit und Verwendungen der Vorrichtung |
CN119142675B (zh) * | 2024-11-18 | 2025-02-07 | 山东中瑞源生物科技有限公司 | 一种自体脂肪干细胞预处理设备 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1329559C (en) * | 1988-03-03 | 1994-05-17 | Keiji Naoi | Leukocyte separator and method of making the same |
JP3322595B2 (ja) * | 1996-03-28 | 2002-09-09 | テルモ株式会社 | フィルター装置および生体微細組織の分離・回収方法 |
US6120474A (en) * | 1997-12-15 | 2000-09-19 | Nissho Corporation | Blood component-recovering apparatus and a method for recovering blood components using the same |
-
1998
- 1998-09-14 JP JP27936498A patent/JP3517359B2/ja not_active Expired - Lifetime
-
1999
- 1999-09-13 AT AT99118189T patent/ATE337035T1/de not_active IP Right Cessation
- 1999-09-13 DE DE69932901T patent/DE69932901T2/de not_active Expired - Lifetime
- 1999-09-13 EP EP99118189A patent/EP0987034B1/de not_active Expired - Lifetime
- 1999-09-14 US US09/395,740 patent/US6312950B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3517359B2 (ja) | 2004-04-12 |
US6312950B1 (en) | 2001-11-06 |
EP0987034A2 (de) | 2000-03-22 |
ATE337035T1 (de) | 2006-09-15 |
DE69932901T2 (de) | 2007-03-01 |
EP0987034A3 (de) | 2000-10-04 |
EP0987034B1 (de) | 2006-08-23 |
JP2000083649A (ja) | 2000-03-28 |
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