JP4750222B2
(ja)
*
|
1998-09-03 |
2011-08-17 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
JP4689781B2
(ja)
*
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
GB0024444D0
(en)
*
|
2000-10-05 |
2000-11-22 |
Glaxo Group Ltd |
Novel protein
|
CA2449482A1
(en)
*
|
2001-06-05 |
2002-12-12 |
Exelixis, Inc. |
Chds as modifiers of the p53 pathway and methods of use
|
EP2000148A1
(de)
|
2001-06-20 |
2008-12-10 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakarzinom
|
US20050272120A1
(en)
|
2001-06-20 |
2005-12-08 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US7803915B2
(en)
*
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
EP1439228B1
(de)
*
|
2001-09-28 |
2010-05-05 |
J-Pharma Co., Ltd. |
Neutrale aminosäure von geringer grösse transportierender natriumunabhängiger transporter, dessen gen und verfahren zur analyse der transporterfunktion mittels konstruktion von die spezifizierung der funktion ermöglichenden fusionsproteinen
|
JP4278906B2
(ja)
|
2002-02-18 |
2009-06-17 |
ジェイファーマ株式会社 |
酸性アミノ酸を輸送するナトリウム非依存性トランスポーター及びその遺伝子
|
CA2493870C
(en)
*
|
2002-03-13 |
2010-07-20 |
Creighton University |
Device and method for detecting antibiotic inactivating enzymes
|
CA2469992A1
(en)
*
|
2003-06-06 |
2004-12-06 |
F. Hoffmann-La Roche Ag |
Transgenic animal model for glyt1 function
|
EP1483962A3
(de)
*
|
2003-06-06 |
2005-01-12 |
F. Hoffmann-La Roche Ag |
Transgenes Tiermodel für Glyt1 Funktion
|
AU2004316290C1
(en)
|
2003-11-06 |
2012-02-02 |
Seagen Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
US7462459B2
(en)
*
|
2004-01-30 |
2008-12-09 |
Xenoport, Inc. |
LAT1 transporters expressed in blood brain barrier cells
|
JP4560314B2
(ja)
*
|
2004-03-17 |
2010-10-13 |
ジェイファーマ株式会社 |
中性アミノ酸トランスポーターによる癌の検出法、及びそのためのキット
|
JP5234734B2
(ja)
|
2004-06-01 |
2013-07-10 |
ジェネンテック, インコーポレイテッド |
抗体−薬物結合体および方法
|
US20060003920A1
(en)
*
|
2004-06-04 |
2006-01-05 |
Xenoport, Inc. |
LAT1 transporters expressed in cancer cells
|
TR201808537T4
(tr)
|
2004-09-23 |
2018-07-23 |
Genentech Inc |
Sistein değiştirilmiş antikorlar ve konjugatlar.
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
WO2007084715A2
(en)
*
|
2006-01-19 |
2007-07-26 |
Caprion Pharmaceuticals, Inc. |
Tat-031 and methods of assessing and treating cancer
|
TWI390034B
(zh)
|
2006-04-06 |
2013-03-21 |
Kyowa Hakko Kirin Co Ltd |
Novel anti-CD98 antibody
|
CN105372425A
(zh)
*
|
2007-02-06 |
2016-03-02 |
J制药股份有限公司 |
前列腺癌的恶性程度判定试剂盒和其方法
|
EP2977761A1
(de)
|
2007-02-06 |
2016-01-27 |
J-Pharma Co., Ltd. |
Antikörper zum nachweis von prostatakrebsmalignität
|
WO2008108994A1
(en)
*
|
2007-03-01 |
2008-09-12 |
Carnegie Institution Of Washington |
Trp/his exchange and kynurenine induced trp transport
|
EP2303332B1
(de)
|
2008-07-15 |
2014-12-31 |
Genentech, Inc. |
Anthracyclinkonjugate, verfahren zu deren herstellung und deren verwendung als antitumormittel
|
WO2011017049A1
(en)
*
|
2009-07-27 |
2011-02-10 |
Cardiac Pacemakers, Inc. |
Medical device for treating heart failure through blood volume redistribution
|
JP2013504585A
(ja)
|
2009-09-09 |
2013-02-07 |
セントローズ, エルエルシー |
細胞外標的化薬物複合体
|
US20130052197A1
(en)
|
2010-03-26 |
2013-02-28 |
The University Of Tokushima |
Novel anti-cd98 antibody and use thereof
|
US9021394B2
(en)
*
|
2010-04-01 |
2015-04-28 |
Eventsq Llc |
Capturing user feedback of software content in a networked environment and controlling the software using a single action
|
EA024730B1
(ru)
|
2010-04-15 |
2016-10-31 |
Медимьюн Лимитед |
Пирролбензодиазепиновые соединения, их конъюгаты, фармацевтические композиции, содержащие указанные конъюгаты, и применение указанных конъюгатов
|
CN107335062B
(zh)
|
2010-06-08 |
2021-09-24 |
基因泰克公司 |
半胱氨酸改造的抗体和偶联物
|
JP5866138B2
(ja)
*
|
2010-10-28 |
2016-02-17 |
幸雄 米田 |
骨粗鬆症の予防及び/又は治療剤、骨吸収抑制剤、骨形成促進剤及びそれらのスクリーニング方法
|
JP5889912B2
(ja)
|
2010-11-17 |
2016-03-22 |
ジェネンテック, インコーポレイテッド |
アラニニルメイタンシノール抗体コンジュゲート
|
ES2656988T3
(es)
|
2011-04-15 |
2018-03-01 |
J-Pharma Co., Ltd. |
Biomarcador para el cáncer de mama
|
EP2707723B1
(de)
|
2011-05-12 |
2016-02-10 |
Genentech, Inc. |
Lc-ms/ms-verfahren mit mehrfachreaktionsüberwachung zur erkennung therapeutischer antikörper in tierischen proben mittels rahmensignaturpeptiden
|
BR112014009050B1
(pt)
|
2011-10-14 |
2022-06-21 |
Medimmune Limited |
Conjugado anticorpo-fármaco de pirrolbenzodiazepinas, composição farmacêutica que compreende o mesmo, bem como compostos de pirrolbenzodiazepinas
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
US10736903B2
(en)
|
2012-10-12 |
2020-08-11 |
Medimmune Limited |
Pyrrolobenzodiazepine-anti-PSMA antibody conjugates
|
EP2766048B1
(de)
|
2012-10-12 |
2014-12-10 |
Spirogen Sàrl |
Pyrrolobenzodiazepine und konjugate davon
|
JP6392763B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
ピロロベンゾジアゼピン−抗体結合体
|
CA2887894C
(en)
|
2012-10-12 |
2019-10-29 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
CA2887899C
(en)
|
2012-10-12 |
2020-03-31 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
CN105102068B
(zh)
|
2012-10-12 |
2018-06-01 |
Adc疗法责任有限公司 |
吡咯并苯并二氮杂卓-抗体结合物
|
JP2013063978A
(ja)
*
|
2012-10-24 |
2013-04-11 |
J-Pharma Co Ltd |
抗ヒトlat1モノクローナル抗体及び前立腺がんの悪性度判定キット
|
CN105189507A
(zh)
|
2012-12-21 |
2015-12-23 |
斯皮罗根有限公司 |
吡咯并苯并二氮杂卓及其结合物
|
AU2013366490B9
(en)
|
2012-12-21 |
2018-02-01 |
Medimmune Limited |
Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
|
US20160031887A1
(en)
|
2013-03-13 |
2016-02-04 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
US9649390B2
(en)
|
2013-03-13 |
2017-05-16 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
CA2901941C
(en)
|
2013-03-13 |
2020-04-07 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
CA2918139A1
(en)
|
2013-08-12 |
2015-02-19 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
US9950078B2
(en)
|
2013-10-11 |
2018-04-24 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
EP3054983B1
(de)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
MX2016007578A
(es)
|
2013-12-16 |
2016-10-03 |
Genentech Inc |
Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo [e] indol, y metodos de uso y tratamiento.
|
RU2689388C1
(ru)
|
2013-12-16 |
2019-05-28 |
Дженентек, Инк. |
Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами
|
SG11201604905WA
(en)
|
2013-12-16 |
2016-07-28 |
Genentech Inc |
Peptidomimetic compounds and antibody-drug conjugates thereof
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
JP6622293B2
(ja)
|
2014-09-12 |
2019-12-18 |
ジェネンテック, インコーポレイテッド |
アントラサイクリンジスルフィド中間体、抗体−薬物複合体、及び方法
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
RU2017107502A
(ru)
|
2014-09-12 |
2018-10-12 |
Дженентек, Инк. |
Антитела и конъюгаты, сконструированные введением цистеина
|
SG11201702079UA
(en)
|
2014-09-17 |
2017-04-27 |
Genentech Inc |
Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
|
WO2016083468A1
(en)
|
2014-11-25 |
2016-06-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
AU2015358532C1
(en)
|
2014-12-03 |
2020-10-29 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
JP2015134778A
(ja)
*
|
2015-02-06 |
2015-07-27 |
ジェイファーマ株式会社 |
抗ヒトlat1モノクローナル抗体及び前立腺がんの悪性度判定キット
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
US20170315132A1
(en)
|
2016-03-25 |
2017-11-02 |
Genentech, Inc. |
Multiplexed total antibody and antibody-conjugated drug quantification assay
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
EP3458101B1
(de)
|
2016-05-20 |
2020-12-30 |
H. Hoffnabb-La Roche Ag |
Protac-antikörper-konjugate und verfahren zur verwendung
|
JP7022080B2
(ja)
|
2016-05-27 |
2022-02-17 |
ジェネンテック, インコーポレイテッド |
部位特異的抗体-薬物複合体の特徴付けのための生化学分析的方法
|
WO2017214024A1
(en)
|
2016-06-06 |
2017-12-14 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
JP7093767B2
(ja)
|
2016-08-11 |
2022-06-30 |
ジェネンテック, インコーポレイテッド |
ピロロベンゾジアゼピンプロドラッグ及びその抗体コンジュゲート
|
EP3522933B1
(de)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Verfahren zur herstellung von antikörperarzneimittelkonjugaten
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
HUE054689T2
(hu)
|
2017-02-08 |
2021-09-28 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
WO2018192944A1
(en)
|
2017-04-18 |
2018-10-25 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
KR20190141666A
(ko)
|
2017-04-20 |
2019-12-24 |
에이디씨 테라퓨틱스 에스에이 |
항-axl 항체-약물 접합체로의 병용 요법
|
WO2018229222A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
SI3668874T1
(sl)
|
2017-08-18 |
2022-04-29 |
Medimmune Limited |
Pirolobenzodiazepinski konjugati
|
KR20220156974A
(ko)
|
2017-09-20 |
2022-11-28 |
주식회사 피에이치파마 |
타일란스타틴 유사체
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
CN113056287A
(zh)
|
2018-10-24 |
2021-06-29 |
豪夫迈·罗氏有限公司 |
缀合的化学降解诱导剂及使用方法
|
WO2020123275A1
(en)
|
2018-12-10 |
2020-06-18 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
MX2021010477A
(es)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer.
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
EP4426727A2
(de)
|
2021-11-03 |
2024-09-11 |
Hangzhou Dac Biotech Co., Ltd. |
Spezifische konjugation eines antikörpers
|
TW202432187A
(zh)
|
2022-12-23 |
2024-08-16 |
美商建南德克公司 |
小腦蛋白降解劑結合物及其用途
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|