DE69916488D1 - Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren - Google Patents
Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumorenInfo
- Publication number
- DE69916488D1 DE69916488D1 DE69916488T DE69916488T DE69916488D1 DE 69916488 D1 DE69916488 D1 DE 69916488D1 DE 69916488 T DE69916488 T DE 69916488T DE 69916488 T DE69916488 T DE 69916488T DE 69916488 D1 DE69916488 D1 DE 69916488D1
- Authority
- DE
- Germany
- Prior art keywords
- tumors
- treatment
- pharmaceutical preparations
- preparations containing
- substituted caprolactam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- JBKVHLHDHHXQEQ-UHFFFAOYSA-N epsilon-caprolactam Chemical class O=C1CCCCCN1 JBKVHLHDHHXQEQ-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C07D223/10—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19335498A | 1998-11-17 | 1998-11-17 | |
| US193354 | 1998-11-17 | ||
| PCT/EP1999/008767 WO2000029382A1 (en) | 1998-11-17 | 1999-11-15 | Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69916488D1 true DE69916488D1 (de) | 2004-05-19 |
| DE69916488T2 DE69916488T2 (de) | 2005-03-24 |
Family
ID=22713307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69916488T Expired - Lifetime DE69916488T2 (de) | 1998-11-17 | 1999-11-15 | Substituierte caprolactam-derivate, diese enthaltende pharmazeutische zubereitungen sowie ihre verwendung zur behandlung von tumoren |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1131297B1 (de) |
| JP (1) | JP3550545B2 (de) |
| KR (1) | KR20010080461A (de) |
| CN (1) | CN1187333C (de) |
| AR (1) | AR023914A1 (de) |
| AT (1) | ATE264309T1 (de) |
| AU (1) | AU748016B2 (de) |
| BR (1) | BR9915436A (de) |
| CA (1) | CA2347773C (de) |
| CO (1) | CO5140099A1 (de) |
| CZ (1) | CZ20011707A3 (de) |
| DE (1) | DE69916488T2 (de) |
| ES (1) | ES2221463T3 (de) |
| HU (1) | HUP0104224A3 (de) |
| ID (1) | ID28343A (de) |
| IL (1) | IL142701A0 (de) |
| NO (1) | NO20012428L (de) |
| PE (1) | PE20001241A1 (de) |
| PL (1) | PL347633A1 (de) |
| PT (1) | PT1131297E (de) |
| SK (1) | SK6692001A3 (de) |
| TR (1) | TR200101366T2 (de) |
| UY (2) | UY25807A1 (de) |
| WO (1) | WO2000029382A1 (de) |
| ZA (1) | ZA200103419B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001085697A1 (en) * | 2000-05-11 | 2001-11-15 | Novartis Ag | Substituted caprolactam carbonates and ethers and their use as anti-tumor agents |
| WO2002072555A1 (en) * | 2001-03-12 | 2002-09-19 | Novartis Ag | Process for preparing certain substituted caprolactams |
| EP1651633A1 (de) * | 2003-07-25 | 2006-05-03 | Novartis AG | Substituierte lactame und deren verwendung als antikrebsmittel |
| DE10349669B3 (de) * | 2003-10-24 | 2005-05-25 | Aventis Pharma Deutschland Gmbh | Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US7153846B2 (en) | 2003-10-24 | 2006-12-26 | Sanofi-Aventis Deutschland Gmbh | Bengamide derivatives, process for preparing them, and their use |
| FR2878525B1 (fr) * | 2004-11-29 | 2007-02-23 | Aventis Pharma Sa | Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation |
| FR2878528B1 (fr) * | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation |
| FR2901555A1 (fr) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation |
| FR2901556A1 (fr) * | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation |
| FR2901554B1 (fr) | 2006-05-24 | 2011-04-01 | Sanofi Aventis | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation |
| EP2582680A1 (de) | 2010-06-17 | 2013-04-24 | Novartis AG | Biphenyl-substituierte 1,3-dihydro-benzoimidazol-2-ylidenamidderivate |
| JP2013532149A (ja) | 2010-06-17 | 2013-08-15 | ノバルティス アーゲー | ピペリジニル置換１，３−ジヒドロ−ベンゾイミダゾール−２−イリデンアミン誘導体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9411841D0 (en) * | 1994-06-14 | 1994-08-03 | Pharma Mar Sa | New antitumoral compounds from jaspis sponge |
-
1999
- 1999-11-04 CO CO99069674A patent/CO5140099A1/es unknown
- 1999-11-15 SK SK669-2001A patent/SK6692001A3/sk unknown
- 1999-11-15 PT PT99957309T patent/PT1131297E/pt unknown
- 1999-11-15 CN CNB998134104A patent/CN1187333C/zh not_active Expired - Fee Related
- 1999-11-15 PL PL99347633A patent/PL347633A1/xx unknown
- 1999-11-15 EP EP99957309A patent/EP1131297B1/de not_active Expired - Lifetime
- 1999-11-15 ES ES99957309T patent/ES2221463T3/es not_active Expired - Lifetime
- 1999-11-15 WO PCT/EP1999/008767 patent/WO2000029382A1/en active IP Right Grant
- 1999-11-15 AR ARP990105796A patent/AR023914A1/es unknown
- 1999-11-15 AU AU15060/00A patent/AU748016B2/en not_active Ceased
- 1999-11-15 BR BR9915436-6A patent/BR9915436A/pt not_active Application Discontinuation
- 1999-11-15 HU HU0104224A patent/HUP0104224A3/hu unknown
- 1999-11-15 JP JP2000582369A patent/JP3550545B2/ja not_active Expired - Fee Related
- 1999-11-15 KR KR1020017006152A patent/KR20010080461A/ko not_active Ceased
- 1999-11-15 TR TR2001/01366T patent/TR200101366T2/xx unknown
- 1999-11-15 DE DE69916488T patent/DE69916488T2/de not_active Expired - Lifetime
- 1999-11-15 CA CA002347773A patent/CA2347773C/en not_active Expired - Fee Related
- 1999-11-15 AT AT99957309T patent/ATE264309T1/de not_active IP Right Cessation
- 1999-11-15 CZ CZ20011707A patent/CZ20011707A3/cs unknown
- 1999-11-15 PE PE1999001155A patent/PE20001241A1/es not_active Application Discontinuation
- 1999-11-15 ID IDW00200100966A patent/ID28343A/id unknown
- 1999-11-15 IL IL14270199A patent/IL142701A0/xx unknown
- 1999-11-17 UY UY25807A patent/UY25807A1/es unknown
-
2000
- 2000-02-25 UY UY26036A patent/UY26036A1/es unknown
-
2001
- 2001-04-26 ZA ZA200103419A patent/ZA200103419B/en unknown
- 2001-05-16 NO NO20012428A patent/NO20012428L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2221463T3 (es) | 2004-12-16 |
| AR023914A1 (es) | 2002-09-04 |
| JP2002529536A (ja) | 2002-09-10 |
| ATE264309T1 (de) | 2004-04-15 |
| CN1187333C (zh) | 2005-02-02 |
| JP3550545B2 (ja) | 2004-08-04 |
| CZ20011707A3 (cs) | 2001-08-15 |
| CA2347773A1 (en) | 2000-05-25 |
| PL347633A1 (en) | 2002-04-22 |
| UY25807A1 (es) | 2001-08-27 |
| EP1131297B1 (de) | 2004-04-14 |
| BR9915436A (pt) | 2001-08-07 |
| KR20010080461A (ko) | 2001-08-22 |
| TR200101366T2 (tr) | 2001-10-22 |
| EP1131297A1 (de) | 2001-09-12 |
| CN1326445A (zh) | 2001-12-12 |
| NO20012428D0 (no) | 2001-05-16 |
| NO20012428L (no) | 2001-07-17 |
| CO5140099A1 (es) | 2002-03-22 |
| PT1131297E (pt) | 2004-08-31 |
| HUP0104224A3 (en) | 2002-04-29 |
| WO2000029382A1 (en) | 2000-05-25 |
| CA2347773C (en) | 2009-03-10 |
| AU1506000A (en) | 2000-06-05 |
| ID28343A (id) | 2001-05-17 |
| PE20001241A1 (es) | 2000-11-24 |
| DE69916488T2 (de) | 2005-03-24 |
| IL142701A0 (en) | 2002-03-10 |
| SK6692001A3 (en) | 2001-10-08 |
| UY26036A1 (es) | 2001-06-29 |
| HUP0104224A2 (hu) | 2002-03-28 |
| AU748016B2 (en) | 2002-05-30 |
| ZA200103419B (en) | 2002-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |