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DE69831805D1 - Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung - Google Patents

Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung

Info

Publication number
DE69831805D1
DE69831805D1 DE69831805T DE69831805T DE69831805D1 DE 69831805 D1 DE69831805 D1 DE 69831805D1 DE 69831805 T DE69831805 T DE 69831805T DE 69831805 T DE69831805 T DE 69831805T DE 69831805 D1 DE69831805 D1 DE 69831805D1
Authority
DE
Germany
Prior art keywords
groups
equal
preparation
specific biological
homogeneity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831805T
Other languages
English (en)
Other versions
DE69831805T2 (de
Inventor
Frederic Chaubet
Remi Huynh
Latifa Dahri
Jose Correia
Marcel Jozefowicz
Jacqueline Jozefonvicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biodex SARL
Original Assignee
BIODEX ST AMAND LES EAUX
BIODEX ST AMAND LES EAUX
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIODEX ST AMAND LES EAUX, BIODEX ST AMAND LES EAUX filed Critical BIODEX ST AMAND LES EAUX
Application granted granted Critical
Publication of DE69831805D1 publication Critical patent/DE69831805D1/de
Publication of DE69831805T2 publication Critical patent/DE69831805T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69831805T 1997-12-11 1998-12-11 Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung Expired - Lifetime DE69831805T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9715702 1997-12-11
FR9715702A FR2772382B1 (fr) 1997-12-11 1997-12-11 Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique
PCT/FR1998/002699 WO1999029734A1 (fr) 1997-12-11 1998-12-11 Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique

Publications (2)

Publication Number Publication Date
DE69831805D1 true DE69831805D1 (de) 2006-02-16
DE69831805T2 DE69831805T2 (de) 2008-01-24

Family

ID=9514480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831805T Expired - Lifetime DE69831805T2 (de) 1997-12-11 1998-12-11 Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung

Country Status (9)

Country Link
US (1) US6646120B1 (de)
EP (1) EP0990002B1 (de)
JP (1) JP2001523300A (de)
AT (1) ATE305942T1 (de)
AU (1) AU1567799A (de)
CA (1) CA2280949C (de)
DE (1) DE69831805T2 (de)
FR (1) FR2772382B1 (de)
WO (1) WO1999029734A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
FR2794976B1 (fr) * 1999-06-16 2004-05-07 Solutions Compositions pharmaceutiques a action cicatrisante ou anti-complementaire comprenant un derive de dextrane
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
FR2832708B1 (fr) * 2001-11-29 2004-02-13 Organes Tissus Regeneration Re Procede de sulfonation de composes comprenant des groupements hydroxyle (oh) libres ou des amines primaires ou secondaires
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
FR2891149B1 (fr) 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
MX2008012837A (es) * 2006-04-07 2008-10-17 Adocia Polisacaridos bifuncionalizados.
FR2914191A1 (fr) * 2007-03-29 2008-10-03 Proteins & Peptides Man Composition angiogenique.
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
FR2966248B1 (fr) 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
CN102863550B (zh) * 2012-10-25 2014-06-18 西南大学 辛烯基琥珀酸魔芋葡甘聚糖酯制备方法
FR3025428A1 (fr) 2014-09-08 2016-03-11 Adocia Composition pharmaceutique stable comprenant du pdgf
SE538503C2 (en) 2014-11-11 2016-08-16 Tx Medic Ab New dextran sulfate
WO2016160738A2 (en) 2015-04-03 2016-10-06 E I Du Pont De Nemours And Company Gelling dextran ethers
CA2975280A1 (en) 2015-04-03 2016-10-06 E I Du Pont De Nemours And Company Oxidized dextran
CN110382553B (zh) 2016-12-16 2022-06-14 营养与生物科学美国4公司 两亲多糖衍生物和包含其的组合物
CN113286827A (zh) 2018-06-20 2021-08-20 营养与生物科学美国第四公司 多糖衍生物和包含其的组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1152396B (de) * 1960-01-26 1963-08-08 Bernburg Serum Werk Veb Verfahren zur Herstellung von Natriumsalzen blutgerinnungshemmender Dextranschwefelsaeureester
FR2461724A1 (fr) * 1979-07-20 1981-02-06 Christine Fougnot Polymeres substitues par des groupes leur conferant des proprietes anti-coagulantes et leur procede de preparation, objets constitues par et/ou comprenant lesdits polymeres et leurs procedes de fabrication, application desdits objets en chirurgie et en medecine, et compositions pharmaceutiques contenant lesdits polymeres substitues
FR2555589B1 (fr) * 1983-11-30 1986-05-16 Choay Sa Nouveaux derives du dextrane a activites anticoagulante en anti-inflammatoire, leur procede de preparation et utilisation de ces derives en tant qu'anticoagulants et en tant que substituts du plasma sanguin
FR2644066B1 (fr) * 1989-03-09 1994-05-13 Therapeutiques Substitutives Compositions stabilisees comprenant des fgfs, leur procede d'obtention et leurs applications therapeutiques, chirurgicales et cosmetologiques
FR2651436B1 (fr) * 1989-09-05 1994-09-09 Sanofi Sa Compositions pharmaceutiques contenant un derive substitue soluble de dextrane.
FR2657782B1 (fr) * 1990-02-06 1992-05-22 Therapeutiques Substitutives Nouvel agent antitumoral derive du dextrane.

Also Published As

Publication number Publication date
WO1999029734A1 (fr) 1999-06-17
US6646120B1 (en) 2003-11-11
ATE305942T1 (de) 2005-10-15
AU1567799A (en) 1999-06-28
CA2280949C (fr) 2011-03-22
DE69831805T2 (de) 2008-01-24
CA2280949A1 (fr) 1999-06-17
EP0990002A1 (de) 2000-04-05
FR2772382A1 (fr) 1999-06-18
EP0990002B1 (de) 2005-10-05
JP2001523300A (ja) 2001-11-20
FR2772382B1 (fr) 2000-03-03

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Legal Events

Date Code Title Description
8332 No legal effect for de
8328 Change in the person/name/address of the agent

Representative=s name: BOHMANN & LOOSEN, 80335 MUENCHEN

8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIODEX, LYON, FR