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DE69826113D1 - R- und s- enantiomere getrennteteile enthaltende dosierungsformen - Google Patents

R- und s- enantiomere getrennteteile enthaltende dosierungsformen

Info

Publication number
DE69826113D1
DE69826113D1 DE69826113T DE69826113T DE69826113D1 DE 69826113 D1 DE69826113 D1 DE 69826113D1 DE 69826113 T DE69826113 T DE 69826113T DE 69826113 T DE69826113 T DE 69826113T DE 69826113 D1 DE69826113 D1 DE 69826113D1
Authority
DE
Germany
Prior art keywords
enantiomers
dosage form
separate parts
forms containing
dosing forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69826113T
Other languages
English (en)
Other versions
DE69826113T2 (de
Inventor
Clive Gilbert
J Richards
Judith Bardsley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sosei R&D Ltd
Original Assignee
Arakis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9704978.7A external-priority patent/GB9704978D0/en
Priority claimed from GBGB9719261.1A external-priority patent/GB9719261D0/en
Application filed by Arakis Ltd filed Critical Arakis Ltd
Application granted granted Critical
Publication of DE69826113D1 publication Critical patent/DE69826113D1/de
Publication of DE69826113T2 publication Critical patent/DE69826113T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69826113T 1997-03-11 1998-03-11 R- und s- enantiomere getrennteteile enthaltende dosierungsformen Expired - Fee Related DE69826113T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9704978 1997-03-11
GBGB9704978.7A GB9704978D0 (en) 1997-03-11 1997-03-11 Dosage forms
GB9719261 1997-09-10
GBGB9719261.1A GB9719261D0 (en) 1997-09-10 1997-09-10 Dosage forms
PCT/GB1998/000726 WO1998040053A1 (en) 1997-03-11 1998-03-11 Dosage forms comprising separate portions of r- and s-enantiomers
US09/038,873 US6056968A (en) 1997-03-11 1998-03-11 Pharmaceutical drug dosage forms providing different release rates

Publications (2)

Publication Number Publication Date
DE69826113D1 true DE69826113D1 (de) 2004-10-14
DE69826113T2 DE69826113T2 (de) 2005-01-20

Family

ID=27268767

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69826113T Expired - Fee Related DE69826113T2 (de) 1997-03-11 1998-03-11 R- und s- enantiomere getrennteteile enthaltende dosierungsformen

Country Status (15)

Country Link
US (2) US6056968A (de)
EP (1) EP0969818B1 (de)
JP (1) JP2001514651A (de)
CN (1) CN1251987A (de)
AT (1) ATE275394T1 (de)
AU (1) AU741821B2 (de)
BR (1) BR9808325A (de)
CA (1) CA2285407C (de)
DE (1) DE69826113T2 (de)
ES (1) ES2227814T3 (de)
HU (1) HUP0000759A3 (de)
IL (1) IL131713A (de)
NO (1) NO994412L (de)
PL (1) PL335619A1 (de)
WO (1) WO1998040053A1 (de)

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US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
JP2002531431A (ja) * 1998-12-02 2002-09-24 ダーウィン・ディスカバリー・リミテッド 治療用製品およびその使用
AU3064800A (en) * 1999-01-21 2000-08-07 Darwin Discovery Limited The therapeutic use of r-warfarin as anticoagulant
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
WO2001034125A2 (en) * 1999-11-09 2001-05-17 Darwin Discovery Limited Therapeutic use and formulation of (-)-tramadol
DE10004926A1 (de) 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
JP5042425B2 (ja) 2000-03-01 2012-10-03 ユーロセルティック ソシエテ アノニム 機能性胃腸疾患治療用トラマドール
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
WO2002028383A1 (en) * 2000-10-03 2002-04-11 Penwest Pharmaceuticals Company Delivery system for multi-pharmaceutical active materials at various release rates
AU2001297631A1 (en) * 2000-10-24 2002-09-04 Smithkline Beecham Corporation Novel formulations of carvedilol
US6562871B1 (en) * 2000-11-06 2003-05-13 Boehringer Ingelheim Pharmaceuticals, Inc. Dry granulation of pharmaceutical formulation comprising mexiletine
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
IN191028B (de) * 2001-05-17 2003-09-13 Sun Pharmaceutical Ind Ltd
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
AU2002364517A1 (en) 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
EP1562552A1 (de) * 2002-11-08 2005-08-17 Egalet A/S Zusammensetzung zur kontrollierten wirkstoffabgabe von carvedilol
AU2003288608A1 (en) * 2002-12-20 2004-07-14 Ranbaxy Laboratories Limited Controlled release, multiple unit drug delivery systems
CA2515394A1 (en) * 2003-02-10 2004-08-26 Shire Biochem Inc. Enantiomeric amphetamine compositions for the treatment of adhd
WO2004103361A2 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited A pharmaceutical dosage form of citalopram
MXPA05013202A (es) * 2003-06-06 2006-03-09 Ethypharm Sa Tableta de multiples capas oralmente dispersable.
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
JP5072364B2 (ja) * 2003-11-25 2012-11-14 スミスクライン ビーチャム （コーク） リミテッド カルベジロール遊離塩基、カルベジロール塩、無水形態またはその溶媒和物、対応する医薬組成物、制御放出処方および治療またはデリバリー方法
CA2580329C (en) 2004-09-13 2015-01-06 Chrono Therapeutics Inc. Biosynchronous transdermal drug delivery
CA2581282A1 (en) * 2004-10-01 2006-04-13 Nippon Zoki Pharmaceutical Co., Ltd. Solid pharmaceutical preparation
US7829120B2 (en) 2005-09-09 2010-11-09 Labopharm Inc. Trazodone composition for once a day administration
US8206742B2 (en) * 2006-01-12 2012-06-26 Wockhardt Ltd. Sustained release compositions of alfuzosin
AU2007232836B2 (en) * 2006-03-30 2012-12-06 Nippon Zoki Pharmaceutical Co., Ltd. Solid pharmaceutical preparation
KR20130122023A (ko) * 2007-02-12 2013-11-06 디엠아이 바이오사이언시스 인코포레이티드 트라마돌의 부작용을 감소시키는 방법
KR20090121315A (ko) * 2007-02-12 2009-11-25 디엠아이 바이오사이언시스 인코포레이티드 조루 및 발기부전을 동시에 치료하는 방법
EP1977746B8 (de) 2007-04-02 2014-09-24 Parkinson's Institute Verfahren und Zusammensetzung zur Verringerung der Nebenwirkungen von therapeutischen Behandlungen
CA2974324A1 (en) 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems
EP3565617A1 (de) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Vorrichtungen und verfahren zur transdermalen wirkstofffreisetzung
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818541A (en) * 1987-08-19 1989-04-04 Schering Corporation Transdermal delivery of enantiomers of phenylpropanolamine
US5145866A (en) * 1991-04-22 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated Method of treating anxiety with the aid of r(+)-3-amino-1-hydroxy-pyrrolidin-2-one
US5204116A (en) * 1991-05-01 1993-04-20 Alza Corporation Dosage form providing immediate therapy followed by prolonged therapy
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
GB9412689D0 (en) * 1994-06-23 1994-08-10 Chiroscience Ltd Cytotoxic agent and its use

Also Published As

Publication number Publication date
DE69826113T2 (de) 2005-01-20
EP0969818A1 (de) 2000-01-12
PL335619A1 (en) 2000-05-08
AU6508998A (en) 1998-09-29
ES2227814T3 (es) 2005-04-01
NO994412L (no) 1999-10-20
IL131713A (en) 2004-08-31
HUP0000759A3 (en) 2000-11-28
IL131713A0 (en) 2001-03-19
CN1251987A (zh) 2000-05-03
NO994412D0 (no) 1999-09-10
JP2001514651A (ja) 2001-09-11
CA2285407A1 (en) 1998-09-17
CA2285407C (en) 2006-08-01
AU741821B2 (en) 2001-12-13
ATE275394T1 (de) 2004-09-15
US6221394B1 (en) 2001-04-24
US6056968A (en) 2000-05-02
EP0969818B1 (de) 2004-09-08
BR9808325A (pt) 2000-05-16
HUP0000759A2 (hu) 2000-10-28
WO1998040053A1 (en) 1998-09-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee