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DE69729283D1 - GLYKOSYLIERTE IgG ANTIKÖRPER - Google Patents

GLYKOSYLIERTE IgG ANTIKÖRPER

Info

Publication number
DE69729283D1
DE69729283D1 DE69729283T DE69729283T DE69729283D1 DE 69729283 D1 DE69729283 D1 DE 69729283D1 DE 69729283 T DE69729283 T DE 69729283T DE 69729283 T DE69729283 T DE 69729283T DE 69729283 D1 DE69729283 D1 DE 69729283D1
Authority
DE
Germany
Prior art keywords
antibody
fragment
igg antibodies
glycosylated
glycosylated igg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69729283T
Other languages
English (en)
Other versions
DE69729283T2 (de
Inventor
Shui-On Leung
Hans Hansen
Zhengxing Qu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunomedics Inc
Original Assignee
Immunomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunomedics Inc filed Critical Immunomedics Inc
Application granted granted Critical
Publication of DE69729283D1 publication Critical patent/DE69729283D1/de
Publication of DE69729283T2 publication Critical patent/DE69729283T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69729283T 1996-03-20 1997-03-19 GLYKOSYLIERTE IgG ANTIKÖRPER Expired - Lifetime DE69729283T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1370996P 1996-03-20 1996-03-20
US13709P 1996-03-20
PCT/US1997/004196 WO1997034632A1 (en) 1996-03-20 1997-03-19 Glycosylated humanized b-cell specific antibodies

Publications (2)

Publication Number Publication Date
DE69729283D1 true DE69729283D1 (de) 2004-07-01
DE69729283T2 DE69729283T2 (de) 2005-05-25

Family

ID=21761323

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69729283T Expired - Lifetime DE69729283T2 (de) 1996-03-20 1997-03-19 GLYKOSYLIERTE IgG ANTIKÖRPER

Country Status (8)

Country Link
US (3) US6254868B1 (de)
EP (1) EP0888125B1 (de)
JP (1) JP3904238B2 (de)
AT (1) ATE267610T1 (de)
AU (1) AU705063B2 (de)
CA (1) CA2249320C (de)
DE (1) DE69729283T2 (de)
WO (1) WO1997034632A1 (de)

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WO1997034632A1 (en) 1997-09-25
CA2249320C (en) 2008-12-23
EP0888125B1 (de) 2004-05-26
EP0888125A4 (de) 2001-04-25
AU705063B2 (en) 1999-05-13
JP2000507818A (ja) 2000-06-27
DE69729283T2 (de) 2005-05-25
CA2249320A1 (en) 1997-09-25
US6254868B1 (en) 2001-07-03
JP3904238B2 (ja) 2007-04-11
US20030035800A1 (en) 2003-02-20
US20040258682A1 (en) 2004-12-23
ATE267610T1 (de) 2004-06-15
EP0888125A1 (de) 1999-01-07
AU2531897A (en) 1997-10-10

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