DE69713255D1 - Pharmazeutische Pyridin-Derivate, ihre Herstellungsverfahren und Zwischenprodukte dafür - Google Patents
Pharmazeutische Pyridin-Derivate, ihre Herstellungsverfahren und Zwischenprodukte dafürInfo
- Publication number
- DE69713255D1 DE69713255D1 DE69713255T DE69713255T DE69713255D1 DE 69713255 D1 DE69713255 D1 DE 69713255D1 DE 69713255 T DE69713255 T DE 69713255T DE 69713255 T DE69713255 T DE 69713255T DE 69713255 D1 DE69713255 D1 DE 69713255D1
- Authority
- DE
- Germany
- Prior art keywords
- protected
- unprotected
- pharmaceutical
- manufacturing processes
- pyridine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Seasonings (AREA)
- Press Drives And Press Lines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33335796 | 1996-12-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69713255D1 true DE69713255D1 (de) | 2002-07-18 |
| DE69713255T2 DE69713255T2 (de) | 2002-11-07 |
Family
ID=18265214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69713255T Expired - Lifetime DE69713255T2 (de) | 1996-12-13 | 1997-12-10 | Pharmazeutische Pyridin-Derivate, ihre Herstellungsverfahren und Zwischenprodukte dafür |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5965730A (de) |
| EP (1) | EP0848000B1 (de) |
| KR (1) | KR100416833B1 (de) |
| CN (1) | CN1127498C (de) |
| AT (1) | ATE219075T1 (de) |
| CA (1) | CA2224635C (de) |
| DE (1) | DE69713255T2 (de) |
| DK (1) | DK0848000T3 (de) |
| ES (1) | ES2178741T3 (de) |
| HK (1) | HK1012505A1 (de) |
| ID (1) | ID19155A (de) |
| PT (1) | PT848000E (de) |
| SG (1) | SG53130A1 (de) |
| TW (1) | TW429257B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1302677B1 (it) | 1998-10-15 | 2000-09-29 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| ID30057A (id) * | 1999-02-18 | 2001-11-01 | Hoffmann La Roche | Turunan fenilalaninol |
| TR200201317T2 (tr) | 1999-08-21 | 2002-11-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Sinerjistik kombinasyon. |
| WO2001068600A2 (en) | 2000-03-16 | 2001-09-20 | Inflazyme Pharmaceuticals Limited | Benzylated pde4 inhibitors |
| AR029289A1 (es) * | 2000-07-05 | 2003-06-18 | Ishihara Sangyo Kaisha | Derivado de benzoilpiridina o su sal, fungicida que lo contiene como un ingrediente activo, su proceso de produccion e intermediario para producirlo |
| EP1389467B1 (de) * | 2001-05-23 | 2013-07-03 | Mitsubishi Tanabe Pharma Corporation | Therapeutische Zusammensetzungen für die regenerative Behandlung von Knorpelerkrankungen |
| US20040146561A1 (en) | 2001-05-23 | 2004-07-29 | Naoki Sakurai | Compositions for promoting healing of bone fracture |
| US20050043315A1 (en) * | 2002-01-02 | 2005-02-24 | Hideo Tsutsumi | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them |
| WO2004087211A2 (en) | 2003-04-01 | 2004-10-14 | Applied Research Systems Ars Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| US7691879B2 (en) | 2003-09-23 | 2010-04-06 | Merck Sharp & Dohme Corp. | Isoquinoline potassium channel inhibitors |
| TWI339578B (en) * | 2004-10-29 | 2011-04-01 | Mitsubishi Tanabe Pharma Corp | Use of a pyridine compound for the preparation of a medicament for the treatment of skin lesions |
| KR101002168B1 (ko) | 2005-10-05 | 2010-12-17 | 미쓰비시 타나베 파마 코퍼레이션 | 피부염 치료제 |
| JP2009528365A (ja) * | 2006-02-28 | 2009-08-06 | アムゲン インコーポレイティッド | ホスホジエステラーゼ１０阻害剤としてのシンノリン及びキナゾリン誘導体 |
| SI2767537T1 (sl) | 2008-08-06 | 2017-08-31 | Medivation Technologies, Inc. | Dihidropiridoftalazinonski inhibitorji poli(adp-riboza) polimeraze (parp) |
| CN102869258A (zh) | 2010-02-03 | 2013-01-09 | 生物马林药物股份有限公司 | 用于pten基因缺失相关疾病的治疗的聚（adp-核糖）聚合酶（parp）的二氢吡啶并酞嗪酮抑制剂 |
| AU2011213584B2 (en) | 2010-02-08 | 2016-05-12 | Medivation Technologies Llc | Processes of synthesizing dihydropyridophthalazinone derivatives |
| RU2438672C1 (ru) * | 2010-04-30 | 2012-01-10 | Общество с ограниченной ответственностью "Клевер Фарм" | Агент, проявляющий свойства активатора когнитивных функций (варианты) |
| PT2630146T (pt) | 2010-10-21 | 2020-07-20 | Medivation Tech Llc | Sal tosilato de (8s,9r)-5-fluoro-8-(4-fluorofenil)-9-(1-metil-1h-1,2,4-triazol-5-il)-8,9-di-hidro-2h-pirido[4,3,2-de]ftalazin-3(7h)-ona cristalino |
| KR20180048827A (ko) * | 2015-09-02 | 2018-05-10 | 바스프 에스이 | 윤활제 조성물 |
| CN108658937A (zh) * | 2017-03-28 | 2018-10-16 | 中国海洋大学 | 一种双环生物碱类化合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9027055D0 (en) * | 1990-12-13 | 1991-02-06 | Sandoz Ltd | Organic compounds |
| JP3042156B2 (ja) * | 1992-02-20 | 2000-05-15 | 田辺製薬株式会社 | ナフタレン誘導体、その製法及びその合成中間体 |
| GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
| IL118469A (en) * | 1995-06-15 | 2000-08-13 | Tanabe Seiyaku Co | Naphthalene derivatives their preparation and intermediates thereof |
-
1997
- 1997-11-27 ID IDP973785A patent/ID19155A/id unknown
- 1997-12-02 SG SG1997004224A patent/SG53130A1/en unknown
- 1997-12-04 US US08/985,042 patent/US5965730A/en not_active Expired - Lifetime
- 1997-12-05 TW TW086118300A patent/TW429257B/zh not_active IP Right Cessation
- 1997-12-10 AT AT97309947T patent/ATE219075T1/de active
- 1997-12-10 PT PT97309947T patent/PT848000E/pt unknown
- 1997-12-10 DE DE69713255T patent/DE69713255T2/de not_active Expired - Lifetime
- 1997-12-10 EP EP97309947A patent/EP0848000B1/de not_active Expired - Lifetime
- 1997-12-10 ES ES97309947T patent/ES2178741T3/es not_active Expired - Lifetime
- 1997-12-10 DK DK97309947T patent/DK0848000T3/da active
- 1997-12-11 CA CA002224635A patent/CA2224635C/en not_active Expired - Fee Related
- 1997-12-11 KR KR1019970067848A patent/KR100416833B1/ko not_active IP Right Cessation
- 1997-12-12 CN CN97125491A patent/CN1127498C/zh not_active Expired - Fee Related
-
1998
- 1998-12-17 HK HK98113891A patent/HK1012505A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1012505A1 (en) | 1999-08-06 |
| ATE219075T1 (de) | 2002-06-15 |
| KR19980064040A (ko) | 1998-10-07 |
| EP0848000B1 (de) | 2002-06-12 |
| ID19155A (id) | 1998-06-18 |
| MX9710182A (es) | 1998-10-31 |
| EP0848000A1 (de) | 1998-06-17 |
| ES2178741T3 (es) | 2003-01-01 |
| DE69713255T2 (de) | 2002-11-07 |
| DK0848000T3 (da) | 2002-09-30 |
| US5965730A (en) | 1999-10-12 |
| TW429257B (en) | 2001-04-11 |
| KR100416833B1 (ko) | 2004-05-24 |
| PT848000E (pt) | 2002-09-30 |
| CN1184813A (zh) | 1998-06-17 |
| SG53130A1 (en) | 1998-09-28 |
| CN1127498C (zh) | 2003-11-12 |
| CA2224635C (en) | 2006-01-31 |
| CA2224635A1 (en) | 1998-06-13 |
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| CA2178974A1 (en) | Naphthalene derivatives, processes for the preparation thereof, and intermediates therefor | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |