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DE69634818D1 - Nanopartikeln für die perorale verabreichung von schwerlöslichen arzneimittel - Google Patents

Nanopartikeln für die perorale verabreichung von schwerlöslichen arzneimittel

Info

Publication number
DE69634818D1
DE69634818D1 DE69634818T DE69634818T DE69634818D1 DE 69634818 D1 DE69634818 D1 DE 69634818D1 DE 69634818 T DE69634818 T DE 69634818T DE 69634818 T DE69634818 T DE 69634818T DE 69634818 D1 DE69634818 D1 DE 69634818D1
Authority
DE
Germany
Prior art keywords
medicaments
nanoparticles
duty
heavy
peroral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69634818T
Other languages
English (en)
Other versions
DE69634818T2 (de
Inventor
Robert Gurny
Olivier Allemann
Jean-Christophe Leroux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69634818D1 publication Critical patent/DE69634818D1/de
Application granted granted Critical
Publication of DE69634818T2 publication Critical patent/DE69634818T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69634818T 1995-05-08 1996-04-26 Nanopartikeln für die perorale verabreichung von schwerlöslichen arzneimittel Expired - Lifetime DE69634818T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95810306 1995-05-08
EP95810306 1995-05-08
PCT/EP1996/001769 WO1996035414A1 (en) 1995-05-08 1996-04-26 Nanoparticles for oral administration of pharmaceutical agents of low solubility

Publications (2)

Publication Number Publication Date
DE69634818D1 true DE69634818D1 (de) 2005-07-14
DE69634818T2 DE69634818T2 (de) 2006-03-23

Family

ID=8221740

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69634818T Expired - Lifetime DE69634818T2 (de) 1995-05-08 1996-04-26 Nanopartikeln für die perorale verabreichung von schwerlöslichen arzneimittel

Country Status (13)

Country Link
EP (1) EP0835103B1 (de)
JP (1) JP4128621B2 (de)
AR (1) AR002049A1 (de)
AT (1) ATE297195T1 (de)
AU (1) AU5811996A (de)
CA (1) CA2219777C (de)
DE (1) DE69634818T2 (de)
ES (1) ES2243952T3 (de)
IL (1) IL118162A (de)
PT (1) PT835103E (de)
TW (1) TW493991B (de)
WO (1) WO1996035414A1 (de)
ZA (1) ZA963584B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
EP0901786B1 (de) 1997-08-11 2007-06-13 Pfizer Products Inc. Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit
US6350786B1 (en) 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US7119085B2 (en) * 2000-03-23 2006-10-10 Elan Pharmaceuticals, Inc. Methods to treat alzheimer's disease
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
ATE314343T1 (de) 2000-06-30 2006-01-15 Elan Pharm Inc Verbindungen zur behandlung der alzheimerischen krankheit
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
GB0216700D0 (en) 2002-07-18 2002-08-28 Astrazeneca Ab Process
GB0302673D0 (en) 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US8246986B2 (en) 2003-09-26 2012-08-21 Alza Corporation Drug coating providing high drug loading
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20080213383A1 (en) * 2005-09-06 2008-09-04 Astellas Pharma Inc. Fine particles of poorly water-soluble drug having enteric material adsorbed on particle surface
US20090004231A1 (en) 2007-06-30 2009-01-01 Popp Shane M Pharmaceutical dosage forms fabricated with nanomaterials for quality monitoring
TW200946266A (en) * 2008-02-27 2009-11-16 Kuraray Co Method of manufacturing metalnanowire and dispersion medium comprising the resultant metalnanowire, and transparent conductive film
WO2010084060A1 (en) 2009-01-21 2010-07-29 Basf Se Starch copolymers and nanoparticles thereof for drug delivery systems
WO2010084088A2 (en) 2009-01-21 2010-07-29 Basf Se Starch nanoparticles for drug delivery systems
GB201006038D0 (en) 2010-04-12 2010-05-26 Unilever Plc Improvements relating to antiviral compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
US5382435A (en) * 1993-03-24 1995-01-17 Southwest Research Institute Microparticulate pharmaceutical delivery system

Also Published As

Publication number Publication date
JPH11504638A (ja) 1999-04-27
CA2219777A1 (en) 1996-11-14
AR002049A1 (es) 1998-01-07
CA2219777C (en) 2007-06-12
JP4128621B2 (ja) 2008-07-30
IL118162A0 (en) 1996-09-12
DE69634818T2 (de) 2006-03-23
EP0835103A1 (de) 1998-04-15
ZA963584B (en) 1996-11-08
IL118162A (en) 2001-10-31
EP0835103B1 (de) 2005-06-08
ATE297195T1 (de) 2005-06-15
WO1996035414A1 (en) 1996-11-14
AU5811996A (en) 1996-11-29
PT835103E (pt) 2005-10-31
ES2243952T3 (es) 2005-12-01
TW493991B (en) 2002-07-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

R082 Change of representative

Ref document number: 835103

Country of ref document: EP

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN, DE