DE69621225D1 - Tricyclische vasopressin antagonisten - Google Patents

Tricyclische vasopressin antagonisten

Info

Publication number: DE69621225D1
Authority: DE; Germany
Prior art keywords: vasopressin antagonists; tricyclic; tricyclic vasopressin; antagonists; vasopressin
Prior art date: 1995-01-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69621225T

Other languages

English (en)

Other versions

DE69621225T2 (de

Inventor

Mudumbai Venkatesan

Donald Albright

Theodore Grosu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-17

Filing date

1996-01-16

Publication date

2002-06-20

1996-01-16 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

2002-06-20 Application granted granted Critical

2002-06-20 Publication of DE69621225D1 publication Critical patent/DE69621225D1/de

2002-11-14 Publication of DE69621225T2 publication Critical patent/DE69621225T2/de

2016-01-17 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Gastroenterology & Hepatology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE69621225T 1995-01-17 1996-01-16 Tricyclische vasopressin antagonisten Expired - Fee Related DE69621225T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/373,125 US5521173A (en)	1995-01-17	1995-01-17	Tricyclic benzazepine vasopressin antagonists
PCT/US1996/000515 WO1996022292A1 (en)	1995-01-17	1996-01-16	Tricyclic vasopressin antagonists

Publications (2)

Publication Number	Publication Date
DE69621225D1 true DE69621225D1 (de)	2002-06-20
DE69621225T2 DE69621225T2 (de)	2002-11-14

Family

ID=23471074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69621225T Expired - Fee Related DE69621225T2 (de)	1995-01-17	1996-01-16	Tricyclische vasopressin antagonisten

Country Status (23)

Country	Link
US (2)	US5521173A (de)
EP (1)	EP0805813B1 (de)
JP (2)	JP4156664B2 (de)
CN (1)	CN1052725C (de)
AR (1)	AR002021A1 (de)
AT (1)	ATE217625T1 (de)
AU (1)	AU707881B2 (de)
BR (1)	BR9607177A (de)
CA (1)	CA2210708C (de)
CZ (1)	CZ224797A3 (de)
DE (1)	DE69621225T2 (de)
DK (1)	DK0805813T3 (de)
EA (1)	EA000056B1 (de)
ES (1)	ES2175066T3 (de)
HU (1)	HUP9702459A3 (de)
IL (1)	IL116774A (de)
MX (1)	MX9705414A (de)
NZ (1)	NZ301198A (de)
PT (1)	PT805813E (de)
TW (1)	TW472056B (de)
UA (1)	UA48960C2 (de)
WO (1)	WO1996022292A1 (de)
ZA (1)	ZA96303B (de)

Families Citing this family (57)

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US5736540A (en) *	1993-07-29	1998-04-07	American Cyanamid Company	Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5700796A (en) *	1995-01-17	1997-12-23	American Cyanamid Company	Tricyclic benzazepine vasopressin antagonists
US5753648A (en) *	1995-01-17	1998-05-19	American Cyanamid Company	Tricyclic benzazepine vasopressin antagonists
US5880122A (en) *	1996-11-01	1999-03-09	American Home Products Corporation	3-Carboxamide derivatives of 5H-pyrrolo 2,1-c! 1,4!-benzodiazepines
AU732214C (en)	1997-03-31	2001-10-25	Wakamoto Pharmaceutical Co., Ltd.	Biphenyl derivatives and drug composition
US6511974B1 (en)	1997-07-30	2003-01-28	Wyeth	Tricyclic vasopressin agonists
AU756959B2 (en) *	1997-07-30	2003-01-30	Wyeth	Tricyclic vasopressin agonists
US6194407B1 (en)	1997-07-30	2001-02-27	American Home Products Corporation	Tricyclic pyrido vasopressin agonists
US7138393B2 (en) *	1998-07-24	2006-11-21	Wyeth	Biologically active vasopressin agonist metabolites
US6090803A (en) *	1998-07-24	2000-07-18	American Home Products Corporation	Tricyclic vasopressin agonists
RU2250899C2 (ru) *	1999-01-19	2005-04-27	Орто-Макнейл Фармасьютикал, Инк.	Трициклические бензодиазепины, фармацевтическая композиция на их основе и способы лечения гипертензии
KR100771184B1 (ko)	1999-01-19	2007-10-29	오르토-맥네일 파마슈티칼, 인코퍼레이티드	바소프레신 수용체 길항제로서의 트리사이클릭 벤조디아제핀
US6235900B1 (en)	1999-02-04	2001-05-22	American Home Products Corporation	Tricyclic pyridine N-oxides vasopressin agonists
JP2002536377A (ja) *	1999-02-04	2002-10-29	ワイス	バソプレシンアゴニストとしてのチエエニルベンゾイルベンズアゼピン類
US6344451B1 (en)	1999-02-04	2002-02-05	American Home Products	Pyrrolobenzodiazepine carboxyamide vasopressin agonists
US6620807B1 (en)	1999-02-04	2003-09-16	Wyeth	Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists
US6297234B1 (en)	1999-02-04	2001-10-02	American Home Products Corporation	Arylthiophene vasopressin agonists
AU7615200A (en) *	1999-09-27	2001-04-30	American Cyanamid Company	Vasopressin agonist formulation and process
US7189754B2 (en) *	2001-03-20	2007-03-13	Applied Research Systems Ars Holding Nv	Pyrrolidine ester derivatives with oxytocin modulating activity
US6977254B2 (en) *	2001-04-12	2005-12-20	Wyeth	Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
EP1381608B1 (de) *	2001-04-12	2007-10-10	Wyeth	Cyclohexylphenyl vasopressin agonisten
US6903087B2 (en) *	2001-04-12	2005-06-07	Wyeth	Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7022699B2 (en) *	2001-04-12	2006-04-04	Wyeth	Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
US7326700B2 (en) *	2001-04-12	2008-02-05	Wyeth	Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US6900200B2 (en) *	2001-04-12	2005-05-31	Wyeth	Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US7064120B2 (en) *	2001-04-12	2006-06-20	Wyeth	Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US7109193B2 (en) *	2001-04-12	2006-09-19	Wyeth	Tricyclic diazepines tocolytic oxytocin receptor antagonists
US7202239B2 (en) *	2001-04-12	2007-04-10	Wyeth	Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
JP2004530668A (ja) *	2001-04-12	2004-10-07	ワイス	バソプレッシンアゴニストとしてのｎ−ビフェニルカルボニル−およびｎ−フェニルピリジルカルボニル置換二および三環アゼピンおよびジアゼピン
CA2465497A1 (en) *	2001-10-29	2003-05-08	Ortho-Mcneil Pharmaceutical, Inc.	Bridged bicyclic amino acid-derived (1,4) benzodiazepine vasopressin receptor antagonists
US7119088B2 (en) *	2003-02-19	2006-10-10	Pfizer Inc.	Triazole compounds useful in therapy
WO2008020455A2 (en) *	2006-08-14	2008-02-21	Council Of Scientific & Industrial Research	Pyrrolo[2,1-c][1,4]benzodiazepine hybrids and a process for the preparation thereof
KR20110017431A (ko)	2008-06-10	2011-02-21	아보트 러보러터리즈	신규한 트리사이클릭 화합물
KR101348499B1 (ko)	2008-11-13	2014-01-06	에프. 호프만-라 로슈 아게	스피로-5,6-다이하이드로-4ｈ-2,3,5,10ｂ-테트라아자-벤조〔ｅ〕아줄렌
PE20110590A1 (es)	2008-11-18	2011-08-31	Hoffmann La Roche	Alquilciclohexileteres de dihidrotetraazabenzoazulenos
DK2370441T3 (da)	2008-11-28	2013-10-21	Hoffmann La Roche	Arylcyclohexylethere af dihydrotetraazabenzoazulener til anvendelse som vasopressin v1a-receptorantagonister
CA2781010A1 (en)	2009-12-01	2011-06-09	Abbott Laboratories	Novel tricyclic compounds
CN109053742B (zh)	2009-12-01	2021-06-15	Abbvie 公司	新的三环化合物
US8420633B2 (en)	2010-03-31	2013-04-16	Hoffmann-La Roche Inc.	Aryl-cyclohexyl-tetraazabenzo[e]azulenes
US8461151B2 (en)	2010-04-13	2013-06-11	Hoffmann-La Roche Inc.	Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes
US8492376B2 (en)	2010-04-21	2013-07-23	Hoffmann-La Roche Inc.	Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes
US8481528B2 (en)	2010-04-26	2013-07-09	Hoffmann-La Roche Inc.	Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes
WO2011150457A2 (en)	2010-06-01	2011-12-08	The University Of Queensland	Haematopoietic-prostaglandin d2 synthase inhibitors
CN103288829A (zh) *	2012-02-24	2013-09-11	中国科学院大连化学物理研究所	一种合成手性二氢-5H-吡咯并[2,1-c][1,4]-苯并二氮杂卓-5-酮的方法
WO2014060381A1 (de)	2012-10-18	2014-04-24	Bayer Cropscience Ag	Heterocyclische verbindungen als schädlingsbekämpfungsmittel
EP2914587A1 (de)	2012-10-31	2015-09-09	Bayer CropScience AG	Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
EP3590932B1 (de)	2013-03-14	2023-05-03	Sumitomo Pharma Oncology, Inc.	Jak2- und alk2-inhibitoren und verfahren zu deren verwendung
EP4219503A1 (de)	2015-10-16	2023-08-02	AbbVie Inc.	Kristallines l-maleat von (3s,4r)-3-ethyl-4-(3h-imidazo[1,2-a!pyrrolo[2,3-e!pyrazin-8-yl)-n-(2,2,2-trifluorethyl)pyrrolidin-1-carboxamid
US10550126B2 (en)	2015-10-16	2020-02-04	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US11524964B2 (en)	2015-10-16	2022-12-13	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US11512092B2 (en)	2015-10-16	2022-11-29	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US11365198B2 (en)	2015-10-16	2022-06-21	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US11780848B2 (en)	2015-10-16	2023-10-10	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereof
US12365689B2 (en)	2015-10-16	2025-07-22	Abbvie Inc.	Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
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1995
- 1995-01-17 US US08/373,125 patent/US5521173A/en not_active Expired - Lifetime
1996
- 1996-01-15 ZA ZA96303A patent/ZA96303B/xx unknown
- 1996-01-15 AR ARP960101024A patent/AR002021A1/es unknown
- 1996-01-16 EA EA199700118A patent/EA000056B1/ru not_active IP Right Cessation
- 1996-01-16 CN CN96192570A patent/CN1052725C/zh not_active Expired - Fee Related
- 1996-01-16 CZ CZ972247A patent/CZ224797A3/cs unknown
- 1996-01-16 DE DE69621225T patent/DE69621225T2/de not_active Expired - Fee Related
- 1996-01-16 IL IL11677496A patent/IL116774A/xx not_active IP Right Cessation
- 1996-01-16 CA CA002210708A patent/CA2210708C/en not_active Expired - Fee Related
- 1996-01-16 JP JP52234496A patent/JP4156664B2/ja not_active Expired - Fee Related
- 1996-01-16 AU AU46566/96A patent/AU707881B2/en not_active Ceased
- 1996-01-16 TW TW085100471A patent/TW472056B/zh not_active IP Right Cessation
- 1996-01-16 ES ES96902143T patent/ES2175066T3/es not_active Expired - Lifetime
- 1996-01-16 DK DK96902143T patent/DK0805813T3/da active
- 1996-01-16 MX MX9705414A patent/MX9705414A/es not_active IP Right Cessation
- 1996-01-16 UA UA97084248A patent/UA48960C2/uk unknown
- 1996-01-16 BR BR9607177A patent/BR9607177A/pt not_active IP Right Cessation
- 1996-01-16 NZ NZ301198A patent/NZ301198A/xx unknown
- 1996-01-16 AT AT96902143T patent/ATE217625T1/de not_active IP Right Cessation
- 1996-01-16 HU HU9702459A patent/HUP9702459A3/hu unknown
- 1996-01-16 PT PT96902143T patent/PT805813E/pt unknown
- 1996-01-16 WO PCT/US1996/000515 patent/WO1996022292A1/en not_active Application Discontinuation
- 1996-01-16 EP EP96902143A patent/EP0805813B1/de not_active Expired - Lifetime
- 1996-05-23 US US08/652,198 patent/US5780471A/en not_active Expired - Lifetime
2007
- 2007-11-21 JP JP2007301897A patent/JP2008069176A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
IL116774A (en)	2000-12-06
EP0805813A1 (de)	1997-11-12
MX9705414A (es)	1997-11-29
BR9607177A (pt)	1997-11-11
US5780471A (en)	1998-07-14
DE69621225T2 (de)	2002-11-14
JPH11500424A (ja)	1999-01-12
JP4156664B2 (ja)	2008-09-24
JP2008069176A (ja)	2008-03-27
NZ301198A (en)	1999-08-30
CN1052725C (zh)	2000-05-24
TW472056B (en)	2002-01-11
HUP9702459A3 (en)	2000-08-28
WO1996022292A1 (en)	1996-07-25
AU707881B2 (en)	1999-07-22
IL116774A0 (en)	1996-05-14
EP0805813B1 (de)	2002-05-15
ES2175066T3 (es)	2002-11-16
PT805813E (pt)	2002-10-31
CA2210708A1 (en)	1996-07-25
EA000056B1 (ru)	1998-04-30
AR002021A1 (es)	1998-01-07
CA2210708C (en)	2005-05-24
CN1178532A (zh)	1998-04-08
HUP9702459A2 (hu)	1998-05-28
AU4656696A (en)	1996-08-07
US5521173A (en)	1996-05-28
ATE217625T1 (de)	2002-06-15
EA199700118A1 (ru)	1997-12-30
UA48960C2 (uk)	2002-09-16
ZA96303B (en)	1997-07-15
DK0805813T3 (da)	2002-08-05
CZ224797A3 (cs)	1998-03-18
HK1003891A1 (en)	1998-11-13

Publication	Publication Date	Title
DK0805813T3 (da)	2002-08-05	Tricyclic vasopressin antagonists
DK0804438T3 (da)	2006-06-12	Tricycliske benzazepin-vasopressinantagonister
BR9606977A (pt)	1997-11-04	Antagonistas de vasopressina de benzazepina triciclica
DE69826487D1 (de)	2004-10-28	Trizyclische vasopressin agoniste
ATE381570T1 (de)	2008-01-15	Trizyclische benzazepin-vasopressin-antagoniste
FI943542L (fi)	1995-01-30	Trisyklisiä bentsatsepiineja, jotka ovat vasopressiiniantagonisteja
BR9710087A (pt)	1999-08-10	Antagonistas de vasopressina de benzazepina tricíclicos
DK0738150T3 (da)	2003-08-25	Bicykliske fibrinogene antagonister
NO972016D0 (no)	1997-04-30	Indolyl-Y-reseptorantagonister
DE69719354D1 (de)	2003-04-03	Muscarin-antagonisten
DE69203955D1 (de)	1995-09-14	Benzazepinderivate als Vasopressin-Antagonisten.
IS4664A (is)	1998-02-04	Ný peptíð-ópíóíð
FI960516A7 (fi)	1996-08-07	Substituoituja bifenyylisulfonamidiendoteliiniantagonisteja
DE69630209D1 (de)	2003-11-06	Bicyclische benzazepin-derivate als vasopressin-antagonisten
FI960836A7 (fi)	1996-04-22	Bentsodiatsepiiniyhdisteet, jotka ovat käyttökelpoisia CCK- tai gastriiniantagonisteina
PT964867E (pt)	2005-07-29	Antagonistas da taquicinima
FI943513L (fi)	1994-07-26	Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja
EE9800165A (et)	1998-12-15	Parendatud toimega LHRH antagonistid
FI98053B (fi)	1996-12-31	Sekoitus
KR960029102U (ko)	1996-09-17	가족 납골묘
KR970020767U (ko)	1997-06-18	세면기 고정받침대
BR9612155A (pt)	1999-07-13	Mistura
IT236758Y1 (it)	2000-08-17	Alpestock multiuso
KR970020545U (ko)	1997-06-18	조합식 반지
UA25947C2 (uk)	1999-02-26	Міhhий загороджувач

Legal Events

Date	Code	Title	Description
2003-06-12	8364	No opposition during term of opposition
2004-05-19	8327	Change in the person/name/address of the patent owner	Owner name: WYETH HOLDINGS CORP., MADISON, N.J., US
2010-11-18	8339	Ceased/non-payment of the annual fee