DE69527868D1 - Monoklonaler Antikörper gegen den tumorzytotoxischen Faktor II (TCF-II) - Google Patents

Monoklonaler Antikörper gegen den tumorzytotoxischen Faktor II (TCF-II)

Info

Publication number: DE69527868D1
Authority: DE; Germany
Prior art keywords: tcf; monoclonal antibody; antibody against; against tumor; cytotoxic factor
Prior art date: 1994-03-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69527868T

Other languages

English (en)

Other versions

DE69527868T2 (de

Inventor

Kanji Higashio

Nobuyuki Shima

Fumiko Oogaki

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Atlas Pharmaceuticals Inc Sunnyvale Calif Us

Original Assignee

Daiichi Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-18

Filing date

1995-03-17

Publication date

2002-10-02

1995-03-17 Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd

2002-10-02 Application granted granted Critical

2002-10-02 Publication of DE69527868D1 publication Critical patent/DE69527868D1/de

2003-05-08 Publication of DE69527868T2 publication Critical patent/DE69527868T2/de

2015-03-18 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

206010028980 Neoplasm Diseases 0.000 title 1
108010094028 Prothrombin Proteins 0.000 title 1
AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 title 1
239000003145 cytotoxic factor Substances 0.000 title 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
230000000903 blocking effect Effects 0.000 abstract 1
239000001963 growth medium Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
239000007790 solid phase Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Zoology (AREA)
Immunology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DE69527868T 1994-03-18 1995-03-17 Monoklonaler Antikörper gegen den tumorzytotoxischen Faktor II (TCF-II) Expired - Fee Related DE69527868T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP6074263A JPH07258298A (ja)	1994-03-18	1994-03-18	モノクローナル抗体

Publications (2)

Publication Number	Publication Date
DE69527868D1 true DE69527868D1 (de)	2002-10-02
DE69527868T2 DE69527868T2 (de)	2003-05-08

Family

ID=13542077

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69527868T Expired - Fee Related DE69527868T2 (de)	1994-03-18	1995-03-17	Monoklonaler Antikörper gegen den tumorzytotoxischen Faktor II (TCF-II)

Country Status (11)

Country	Link
US (1)	US5658742A (de)
EP (1)	EP0672685B1 (de)
JP (1)	JPH07258298A (de)
AT (1)	ATE222927T1 (de)
AU (1)	AU684132B2 (de)
CA (1)	CA2145005C (de)
DE (1)	DE69527868T2 (de)
DK (1)	DK0672685T3 (de)
ES (1)	ES2182867T3 (de)
NZ (1)	NZ270743A (de)
ZA (1)	ZA952125B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5821223A (en) *	1990-09-14	1998-10-13	The United States Of America As Represented By The Department Of Health And Human Services	Method of stimulating cell growth with a novel broad spectrum human lung fibroblast-derived mitogen
JP4006058B2 (ja) *	1997-03-11	2007-11-14	第一三共株式会社	多臓器不全予防及び／又は治療剤
DK0950416T3 (da) *	1997-03-14	2007-02-26	Daiichi Seiyaku Co	Anvendelse af TCF-II til behandling af cancerrelateret tab af kropsvægt, anæmi og TNF-forhöjelse
US6548296B1 (en) *	1997-07-23	2003-04-15	Roche Diagnostics Gmbh	Methods for identifying human cell lines useful for endogenous gene activation, isolated human lines identified thereby, and uses thereof
JP2003047470A (ja) *	2001-08-01	2003-02-18	Asahi Kasei Corp	新規な抗体及びその用途
EP2025342B1 (de) *	2006-04-20	2017-07-05	Osaka University	Therapeutisches mittel oder entwicklungshemmer von polyglutamin-krankheit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0597A (ja) *	1991-06-21	1993-01-08	Snow Brand Milk Prod Co Ltd	新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法

1994
- 1994-03-18 JP JP6074263A patent/JPH07258298A/ja active Pending
1995
- 1995-03-15 ZA ZA952125A patent/ZA952125B/xx unknown
- 1995-03-15 US US08/404,643 patent/US5658742A/en not_active Expired - Lifetime
- 1995-03-17 DK DK95301800T patent/DK0672685T3/da active
- 1995-03-17 AU AU14939/95A patent/AU684132B2/en not_active Ceased
- 1995-03-17 ES ES95301800T patent/ES2182867T3/es not_active Expired - Lifetime
- 1995-03-17 NZ NZ270743A patent/NZ270743A/en not_active IP Right Cessation
- 1995-03-17 AT AT95301800T patent/ATE222927T1/de not_active IP Right Cessation
- 1995-03-17 EP EP95301800A patent/EP0672685B1/de not_active Expired - Lifetime
- 1995-03-17 DE DE69527868T patent/DE69527868T2/de not_active Expired - Fee Related
- 1995-03-20 CA CA002145005A patent/CA2145005C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH07258298A (ja)	1995-10-09
EP0672685B1 (de)	2002-08-28
CA2145005C (en)	2005-06-21
NZ270743A (en)	1996-06-25
AU684132B2 (en)	1997-12-04
US5658742A (en)	1997-08-19
CA2145005A1 (en)	1995-09-19
DE69527868T2 (de)	2003-05-08
ATE222927T1 (de)	2002-09-15
AU1493995A (en)	1995-09-28
ES2182867T3 (es)	2003-03-16
ZA952125B (en)	1995-12-14
DK0672685T3 (da)	2003-01-06
EP0672685A3 (de)	1997-01-15
EP0672685A2 (de)	1995-09-20

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Legal Events

Date	Code	Title	Description
2003-09-25	8364	No opposition during term of opposition
2005-06-02	8328	Change in the person/name/address of the agent	Representative=s name: BOETERS & LIECK, 81541 MUENCHEN
2009-11-05	8327	Change in the person/name/address of the patent owner	Owner name: ATLAS PHARMACEUTICALS, INC., SUNNYVALE, CALIF., US
2011-01-20	8339	Ceased/non-payment of the annual fee