[go: up one dir, main page]

DE69432838D1 - Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1 - Google Patents

Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1

Info

Publication number
DE69432838D1
DE69432838D1 DE69432838T DE69432838T DE69432838D1 DE 69432838 D1 DE69432838 D1 DE 69432838D1 DE 69432838 T DE69432838 T DE 69432838T DE 69432838 T DE69432838 T DE 69432838T DE 69432838 D1 DE69432838 D1 DE 69432838D1
Authority
DE
Germany
Prior art keywords
hiv
nucleic acid
detection
immunodeficiency virus
human immunodeficiency
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69432838T
Other languages
English (en)
Other versions
DE69432838T2 (de
Inventor
Sherrol H Mcdonough
Thomas B Ryder
Yeasing Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of DE69432838D1 publication Critical patent/DE69432838D1/de
Publication of DE69432838T2 publication Critical patent/DE69432838T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69432838T 1993-03-26 1994-03-28 Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1 Expired - Lifetime DE69432838T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4074593A 1993-03-26 1993-03-26
US40745 1993-03-26

Publications (2)

Publication Number Publication Date
DE69432838D1 true DE69432838D1 (de) 2003-07-31
DE69432838T2 DE69432838T2 (de) 2004-05-13

Family

ID=21912702

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69432838T Expired - Lifetime DE69432838T2 (de) 1993-03-26 1994-03-28 Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1

Country Status (9)

Country Link
US (2) US6252059B1 (de)
EP (2) EP0617132B1 (de)
JP (1) JP4108118B2 (de)
KR (1) KR100325554B1 (de)
AT (1) ATE243762T1 (de)
AU (1) AU686616B2 (de)
CA (1) CA2159103C (de)
DE (1) DE69432838T2 (de)
WO (1) WO1994023069A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
US5733781A (en) * 1994-07-19 1998-03-31 Gen-Probe Incorporated Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus
US5599662A (en) * 1995-02-17 1997-02-04 Hoffmann-La Roche Inc. Oliconucleotide primers and probes for the detection of HIV-1
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
CA2204641A1 (en) * 1995-09-21 1997-03-27 Kenton L. Lohman Detection of nucleic acids in cells by thermophilic strand displacement amplification
DE19644248A1 (de) * 1996-10-24 1998-04-30 Boehringer Mannheim Gmbh Primer und Probes zum Nachweis von HIV
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
CA2222769C (en) * 1997-01-17 2001-06-12 F. Hoffmann-La Roche Ag Primers for the detection of hiv-1
US5962665A (en) * 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US6001558A (en) * 1997-06-25 1999-12-14 Ortho Clinical Diagnostics, Inc. Amplification and detection of HIV-1 and/or HIV 2
WO1999007898A1 (en) 1997-08-08 1999-02-18 Akzo Nobel N.V. Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of hiv-1
US6846905B2 (en) 1997-08-15 2005-01-25 Abbott Laboratories Antigen constructs useful in the detection and differentiation of antibodies to HIV
US7244570B2 (en) 1998-08-04 2007-07-17 Luminex Molecular Diagnostics, Inc. Methods and compositions for modulating “marginally indiscriminant” hybridizations
DE19850186A1 (de) * 1998-10-30 2000-05-25 Roche Diagnostics Gmbh Neue Primer und Sonden zum Nachweis von HIV
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
US6689879B2 (en) 1998-12-31 2004-02-10 Chiron Corporation Modified HIV Env polypeptides
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
AU3219400A (en) 1999-02-03 2000-08-25 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods and reagents for molecular detection of hiv-1 groups m, n and
US6821770B1 (en) * 1999-05-03 2004-11-23 Gen-Probe Incorporated Polynucleotide matrix-based method of identifying microorganisms
AU781934B2 (en) * 1999-07-09 2005-06-23 Gen-Probe Incorporated Detection of HIV-1 by nucleic acid amplification
AU1777401A (en) * 1999-11-17 2001-05-30 Xiuli Chen Simultaneous detection of hbv, hcv and hiv in plasma samples using a multiplex capture assay
WO2001081624A1 (en) * 2000-04-20 2001-11-01 Virco Bvba Method for mutation detection in hiv using pol sequencing
US6800463B1 (en) * 2000-04-20 2004-10-05 Virco Bvba Method for mutation detection in HIV-1 using pol sequencing
CA2419649C (en) * 2000-09-01 2011-03-08 Gen-Probe Incorporated Amplification of hiv-1 sequences for detection of sequences associated with drug-resistance mutations
US6582920B2 (en) 2000-09-01 2003-06-24 Gen-Probe Incorporated Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations
US6770752B2 (en) 2001-01-09 2004-08-03 Becton, Dickinson And Company Sequences for detection of HIV-1
US6753145B2 (en) * 2001-07-05 2004-06-22 Agilent Technologies, Inc. Buffer composition and method for hybridization of microarrays on adsorbed polymer siliceous surfaces
AU2002320314A1 (en) 2001-07-05 2003-01-21 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
CA2458995C (en) 2001-08-31 2013-04-30 Chiron Corporation Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US7132236B2 (en) * 2001-10-25 2006-11-07 Agilent Technologies, Inc. Composition and method for optimized hybridization using modified solutions
WO2005061735A2 (en) * 2003-12-04 2005-07-07 The Government Of The United States Of America As Represented By The Department Of Health Human Servicees Strand-specific amplification
ATE549421T1 (de) 2003-12-19 2012-03-15 Gen Probe Inc Zusammensetzungen, verfahren und kits zum nachweis der nukleinsäuren von hiv-1 und hiv-2
ATE508203T1 (de) * 2004-01-07 2011-05-15 Hitachi Chemical Res Ct Inc Primer und sonden zum nachweis von hiv
FR2869045A1 (fr) * 2004-04-16 2005-10-21 Bioalliance Pharma Sa Methode d'etude de la variabilite genetique et fonctionnelle du vih et kit pour sa mise en oeuvre
EP1602736A1 (de) * 2004-06-04 2005-12-07 Bio-Rad Pasteur Detektion von HIV Typen und Subtypen
EP1800126B1 (de) 2004-09-08 2014-12-17 The United States of America as represented by the Secretary of Health and Human Services, NIH Zusammensetzungen und verfahren für den nachweis von hiv-1/hiv-2-infektionen
EP1909108B1 (de) 2005-03-10 2019-05-29 Gen-Probe Incorporated Systeme und Verfahren zur Durchführung von Tests zum Nachweis oder zur Quantifizierung von Analyten
WO2006099255A2 (en) 2005-03-10 2006-09-21 Gen-Probe Incorporated Systems and methods to perform assays for detecting or quantifying analytes within samples
JPWO2007055260A1 (ja) * 2005-11-11 2009-04-30 財団法人ヒューマンサイエンス振興財団 人免疫不全ウイルス−1遺伝子検出又は定量用材料,検出又は定量方法,治療用遺伝子断片,及び治療方法
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
JP2010521156A (ja) * 2007-03-16 2010-06-24 454 ライフ サイエンシーズ コーポレイション Hiv薬物耐性バリアントの検出のためのシステムおよび方法
ITRM20070254A1 (it) * 2007-05-03 2008-11-04 Univ Palermo Metodo per la genotipizzazione di hiv-1 e relativi kit diagnostici per la rilevazione di farmaco-resistenze.
US8221981B2 (en) * 2007-07-30 2012-07-17 Argos Therapeutics, Inc. Primers and probes for the amplification and detection of HIV Gag, Rev and Nef polynucleotides
GB0814570D0 (en) 2008-08-08 2008-09-17 Diagnostics For The Real World Isolation of nucleic acid
EP2451979A4 (de) * 2009-07-07 2013-03-13 Agency Science Tech & Res Verfahren zum nachweis des menschlichen immundefizienzvirus vom typ 1 (hiv-1) und kit dafür
WO2012123591A1 (en) * 2011-03-17 2012-09-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for targeting nucleic acids to the nucleus
JP6464086B2 (ja) 2012-08-30 2019-02-06 ジェン−プローブ・インコーポレーテッド 多相核酸増幅
US10406250B2 (en) 2013-11-14 2019-09-10 The General Hospital Corporation Suicide contrast agents targeting HIV reservoirs for theranostic eradication
DE112016003948T5 (de) 2015-08-31 2018-05-09 City Of Sapporo Molekulare verfahren zum beurteilen einer urothelialen erkrankung

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0756010B1 (de) 1983-01-10 2001-07-04 Gen-Probe Incorporated Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren
US9328391B1 (en) 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
CA1341423C (en) 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
US4754065A (en) * 1984-12-18 1988-06-28 Cetus Corporation Precursor to nucleic acid probe
US5008182A (en) * 1986-01-10 1991-04-16 Cetus Corporation Detection of AIDS associated virus by polymerase chain reaction
AU606043B2 (en) 1985-03-28 1991-01-31 F. Hoffmann-La Roche Ag Detection of viruses by amplification and hybridization
ATE88762T1 (de) 1986-08-11 1993-05-15 Siska Diagnostics Inc Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.
US5079351A (en) 1986-11-26 1992-01-07 Cetus Corporation Oligonucleotides and kits for detection of htlvi and htlvii viruses by hybridization
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
WO1989004375A1 (en) 1987-10-23 1989-05-18 Siska Diagnostics, Inc. Lanthanide chelate-tagged nucleic acid probes
US5030557A (en) 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
CA2002076A1 (en) 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
WO1990006995A1 (en) 1988-12-16 1990-06-28 Siska Diagnostics, Inc. Self-sustained sequence replication system
WO1990008840A1 (en) 1989-02-03 1990-08-09 Eastman Kodak Company Nucleic acid test article and its use to detect a predetermined nucleic acid
DK1642987T3 (da) * 1989-06-02 2008-12-01 Pasteur Institut Nucleotidsekvenser dannet ud fra genomerne af retrovirusserne HIV-1, HIV-2 og SIV samt deres anvendelse til opformering af disse virale genomer samt til en vitro-diagnose af infektioner, der stammer fra disse virusser
US5480784A (en) * 1989-07-11 1996-01-02 Gen-Probe Incorporated Nucleic acid sequence amplification methods
US5856088A (en) 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
JPH05504475A (ja) * 1989-11-30 1993-07-15 ファルマシア バイオテック インコーポレイテッド 細胞試料において特定の核酸配列を検出する方法
CA2032203C (en) 1989-12-29 2009-05-19 Christine L. Brakel Amplification capture assay
ATE184321T1 (de) * 1990-01-10 1999-09-15 Chiron Diagnostics Corp Dns-abhängige rns-polymerase-transkripte als reportermoleküle zur signalverstärkung in nukleinsäure-hybridisierungsuntersuchungen
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5166195A (en) 1990-05-11 1992-11-24 Isis Pharmaceuticals, Inc. Antisense inhibitors of the human immunodeficiency virus phosphorothioate oligonucleotides
FR2663949A1 (fr) * 1990-06-29 1992-01-03 Genset Sa Perfectionnements a un procede d'amplification enzymatique in vitro.
AU665338B2 (en) * 1990-07-24 1996-01-04 F. Hoffmann-La Roche Ag The reduction of non-specific amplification during (in vitro) nucleic acid amplification using modified nucleic acid bases
JPH0491790A (ja) * 1990-08-02 1992-03-25 Shionogi & Co Ltd 2段階pcr法
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
WO1992022641A1 (en) * 1991-06-14 1992-12-23 Virogenetics Corporation Immunodeficiency virus recombinant poxvirus vaccine
JPH0830704B2 (ja) * 1991-03-21 1996-03-27 イーストマン コダック カンパニー 核酸増幅のための要素および方法ならびに付着プローブを使用する検出方法
CA2065719A1 (en) * 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
FR2677039B1 (fr) * 1991-05-31 1994-09-09 Cis Bio Int Oligonucleotides, utilisables comme reactifs pour la detection in vitro des infections a retrovirus de type hiv et procede de detection de retrovirus de type hiv.
DE69213112T2 (de) * 1991-06-20 1997-04-03 Hoffmann La Roche Verbesserte Methoden zur Nukleinsäure-Amplifizierung
GB9116042D0 (en) * 1991-07-24 1991-09-11 Royal Free Hosp School Med Diagnostic method
DE69233285T2 (de) * 1991-08-02 2004-11-25 bioMérieux B.V. Quantifikation von Nukleinsäuren
DK173091D0 (da) * 1991-10-11 1991-10-11 Schleroseforeningen The Danish Biologisk materiale
EP0726962B1 (de) * 1991-12-23 2006-06-07 Chiron Corporation Sätze von HIV Sonden für Solution Sandwich Hybridationsverfahren
WO1993020220A1 (en) 1992-03-27 1993-10-14 Whitehead Institute For Biomedical Research Non-infectious hiv particles and uses therefor
EP0642589A4 (de) 1992-05-11 1997-05-21 Ribozyme Pharm Inc Methode und reagenz zur inhibierung der viralen replikation.
ES2048652B1 (es) * 1992-06-05 1994-10-01 Inst De Salud Carlos Iii Procedimientos de amplificacion de genoma para la deteccion e identificacion de secuencias genomicas relacionadas.
US5366885A (en) 1992-06-09 1994-11-22 Barranco Iii Sam C Method and kit for testing tumors for drug sensitivity
WO1994003635A1 (en) * 1992-08-04 1994-02-17 Institute Of Molecular Biology & Biotechnology Rapid amplification and detection of nucleic acids
ES2126620T5 (es) * 1992-10-06 2010-05-21 Siemens Healthcare Diagnostics Products Gmbh Retrovirus del grupo de los vih y su utilizacion.

Also Published As

Publication number Publication date
US20020062016A1 (en) 2002-05-23
KR100325554B1 (ko) 2002-11-02
EP0617132A3 (en) 1995-11-29
EP0617132B1 (de) 2003-06-25
JP4108118B2 (ja) 2008-06-25
AU686616B2 (en) 1998-02-12
DE69432838T2 (de) 2004-05-13
US6252059B1 (en) 2001-06-26
EP0617132A2 (de) 1994-09-28
CA2159103C (en) 2002-03-12
CA2159103A1 (en) 1994-10-13
US6649749B2 (en) 2003-11-18
KR960701219A (ko) 1996-02-24
EP1344837A1 (de) 2003-09-17
JPH08508404A (ja) 1996-09-10
ATE243762T1 (de) 2003-07-15
WO1994023069A1 (en) 1994-10-13
AU6551594A (en) 1994-10-24

Similar Documents

Publication Publication Date Title
DE69432838D1 (de) Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1
ATE237698T1 (de) Primers und sonden zum nachweis von hiv
US5389512A (en) Method for determining the relative amount of a viral nucleic acid segment in a sample by the polymerase chain reaction
ATE185379T1 (de) Nukleotid-sequenzen des genoms von retroviren vom typ hiv-1, hiv-2 und siv, ihre verwendungen zur amplifikation dieser genome und in-vitro-diagnose dieser viralen infektionen
Delwart et al. Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay.
US5589333A (en) In situ polymerase chain reaction
ATE282720T1 (de) Nukleinsäuresequenzen als primer und sonden zur amplifizierung und erkennung von allen hiv-1 subtypen
RU2186112C2 (ru) Олигонуклеотидный праймер, пара праймеров, набор праймеров (варианты), способ их изготовления для амплификации нуклеиновой кислоты вич-1
Nycz et al. Quantitative reverse transcription strand displacement amplification: quantitation of nucleic acids using an isothermal amplification technique
Jurriaans et al. Analysis of human immunodeficiency virus type 1 LTR-LTR junctions in peripheral blood mononuclear cells of infected individuals
Delwart et al. Heteroduplex mobility assays for phylogenetic analysis
Karageorgos et al. Stepwise analysis of reverse transcription in a cell-to-cell human immunodeficiency virus infection model: kinetics and implications
Kumar et al. A Method for the Rapid Screening of Human Blod Samples for the Presence of HIV-1 Sequences: The Probe-Shift Assay
Kostrikis et al. Genotyping HIV-1 and HCV strains by a combinatorial DNA melting assay (COMA)
JP4130487B2 (ja) 核酸の同時増幅方法
Teglbjærg et al. Sensitive non-radioactive detection of HIV-1: use of nested primers for the amplification of HIV DNA
RU93013954A (ru) Способ обнаружения вируса иммунодефицита
González-Villaseñor et al. A solid phase plate assay for HIV-1 genotyping

Legal Events

Date Code Title Description
8364 No opposition during term of opposition