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DE69413829D1 - Antiglucocorticoidsteroide zur behandlung von angststörungen - Google Patents

Antiglucocorticoidsteroide zur behandlung von angststörungen

Info

Publication number
DE69413829D1
DE69413829D1 DE69413829T DE69413829T DE69413829D1 DE 69413829 D1 DE69413829 D1 DE 69413829D1 DE 69413829 T DE69413829 T DE 69413829T DE 69413829 T DE69413829 T DE 69413829T DE 69413829 D1 DE69413829 D1 DE 69413829D1
Authority
DE
Germany
Prior art keywords
pct
anxiety disorders
antiglucocorticoidsteroids
treating anxiety
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69413829T
Other languages
English (en)
Other versions
DE69413829T2 (de
Inventor
Bernardus Wynand Machi Peeters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of DE69413829D1 publication Critical patent/DE69413829D1/de
Publication of DE69413829T2 publication Critical patent/DE69413829T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69413829T 1993-08-04 1994-07-28 Antiglucocorticoidsteroide zur behandlung von angststörungen Expired - Lifetime DE69413829T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93202304 1993-08-04
PCT/EP1994/002513 WO1995004536A1 (en) 1993-08-04 1994-07-28 Antiglucocorticoid steroids for the treatment of anxiety disorders

Publications (2)

Publication Number Publication Date
DE69413829D1 true DE69413829D1 (de) 1998-11-12
DE69413829T2 DE69413829T2 (de) 1999-04-15

Family

ID=8214027

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69413829T Expired - Lifetime DE69413829T2 (de) 1993-08-04 1994-07-28 Antiglucocorticoidsteroide zur behandlung von angststörungen

Country Status (11)

Country Link
US (1) US5741787A (de)
EP (1) EP0712311B1 (de)
JP (1) JP3828926B2 (de)
AT (1) ATE171873T1 (de)
AU (1) AU687088B2 (de)
CA (1) CA2166332C (de)
DE (1) DE69413829T2 (de)
DK (1) DK0712311T3 (de)
ES (1) ES2124905T3 (de)
NZ (1) NZ271363A (de)
WO (1) WO1995004536A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2149496C (en) * 1994-05-19 2006-12-19 Ronald Gebhard 11,21-bisphenyl-19-norpregnane derivatives
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
IL119649A (en) * 1995-11-30 2002-03-10 Akzo Nobel Nv Preparation of Cyclic Kills of History - 3 keto- (5) 10, (-9) 11 steroidadians
EP0780397B1 (de) * 1995-12-22 1998-06-10 Jenapharm GmbH & Co. KG Neue 17alpha-Cyanomethylestra-4,9-dien-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
JP4260886B2 (ja) * 1996-05-01 2009-04-30 アメリカ合衆国 新規の抗プロゲステロンとしての２１―置換プロゲステロン誘導体
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
FR2757400B1 (fr) * 1996-12-19 1999-12-17 Hoechst Marion Roussel Inc Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
ES2230880T3 (es) * 1998-07-30 2005-05-01 Abbott Laboratories Agentes selectivos anti-inflmatorios de glucocorticoides.
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US7250408B2 (en) 2002-12-16 2007-07-31 Bayer Schering Pharma Ag Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility
US20060111577A1 (en) * 2003-02-28 2006-05-25 Kim Hyun K Method for preparing 17 alpha-acetoxy-11beta-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
US8097606B2 (en) * 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
EP2671507A3 (de) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-Informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
MX2011011833A (es) 2009-05-06 2012-01-27 Lab Skin Care Inc Composiciones de administración dérmica que comprenden complejos de partículas de fosfato de calcio-agente activo y métodos para utilizar las mismas.
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6995757B2 (ja) 2015-12-23 2022-01-17 オリック ファーマシューティカルズ，インク． グルココルチコイド受容体の阻害剤
AU2016377702B2 (en) 2015-12-23 2021-03-11 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
PT3523315T (pt) 2016-10-07 2021-04-29 Oric Pharmaceuticals Inc Inibidor de recetor de glucocorticoide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series

Also Published As

Publication number Publication date
US5741787A (en) 1998-04-21
AU687088B2 (en) 1998-02-19
WO1995004536A1 (en) 1995-02-16
JPH09501172A (ja) 1997-02-04
EP0712311A1 (de) 1996-05-22
DE69413829T2 (de) 1999-04-15
JP3828926B2 (ja) 2006-10-04
EP0712311B1 (de) 1998-10-07
DK0712311T3 (da) 1999-06-21
NZ271363A (en) 1999-06-29
CA2166332A1 (en) 1995-02-16
CA2166332C (en) 2005-05-10
ES2124905T3 (es) 1999-02-16
AU7496894A (en) 1995-02-28
ATE171873T1 (de) 1998-10-15

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Legal Events

Date Code Title Description
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8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL

R082 Change of representative

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Country of ref document: EP

Representative=s name: WUESTHOFF & WUESTHOFF PATENT- UND RECHTSANWAEL, DE