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DE69333042D1 - Protein l und entsprechenden proteinhybriden - Google Patents

Protein l und entsprechenden proteinhybriden

Info

Publication number
DE69333042D1
DE69333042D1 DE69333042T DE69333042T DE69333042D1 DE 69333042 D1 DE69333042 D1 DE 69333042D1 DE 69333042 T DE69333042 T DE 69333042T DE 69333042 T DE69333042 T DE 69333042T DE 69333042 D1 DE69333042 D1 DE 69333042D1
Authority
DE
Germany
Prior art keywords
protein
hybrid
corresponding protein
protein hybrid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333042T
Other languages
English (en)
Other versions
DE69333042T2 (de
Inventor
Lars Bjoerck
Ulf Sjoebring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affitech Research AS
Original Assignee
Affitech Research AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affitech Research AS filed Critical Affitech Research AS
Publication of DE69333042D1 publication Critical patent/DE69333042D1/de
Application granted granted Critical
Publication of DE69333042T2 publication Critical patent/DE69333042T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69333042T 1992-04-28 1993-04-28 Protein l und entsprechenden proteinhybriden Expired - Lifetime DE69333042T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9201331 1992-04-28
SE9201331A SE9201331D0 (sv) 1992-04-28 1992-04-28 Protein l och hybridproteiner daerav
PCT/SE1993/000375 WO1993022342A1 (en) 1992-04-28 1993-04-28 Protein l and hybrid proteins thereof

Publications (2)

Publication Number Publication Date
DE69333042D1 true DE69333042D1 (de) 2003-07-17
DE69333042T2 DE69333042T2 (de) 2004-05-06

Family

ID=20386082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333042T Expired - Lifetime DE69333042T2 (de) 1992-04-28 1993-04-28 Protein l und entsprechenden proteinhybriden

Country Status (6)

Country Link
US (2) US6822075B2 (de)
EP (1) EP0662086B1 (de)
JP (1) JP3462209B2 (de)
DE (1) DE69333042T2 (de)
SE (1) SE9201331D0 (de)
WO (1) WO1993022342A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737521B1 (en) * 1990-05-11 2004-05-18 The Rockefeller University Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
SE9201331D0 (sv) * 1992-04-28 1992-04-28 Hightech Receptor C O Active Protein l och hybridproteiner daerav
US7037680B2 (en) * 1993-09-21 2006-05-02 The United States Of America As Represented By The Secretary Of The Army Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy
AUPM885194A0 (en) * 1994-10-14 1994-11-10 Council Of The Queensland Institute Of Medical Research, The Synthetic peptides and vaccines comprising same
WO1997035887A1 (en) * 1996-03-26 1997-10-02 Amrad Operations Pty. Ltd. Precursors of catalytic antibodies
AUPO930697A0 (en) * 1997-09-19 1997-10-09 Walter And Eliza Hall Institute Of Medical Research, The Catalytic antibodies and a method of producing same
US20040154053A1 (en) * 1998-03-20 2004-08-05 Wyatt Paul Signal transduction protein involved in plant dehiscence
AU5874999A (en) 1998-09-14 2000-04-03 Affitech As Immunoglobulin binding protein
US7345217B2 (en) 1998-09-22 2008-03-18 Mendel Biotechnology, Inc. Polynucleotides and polypeptides in plants
US8124348B2 (en) 2000-08-23 2012-02-28 Jonathan Zmuda Oral fluid rapid assay for hepatitis C virus (HCV) antibodies using non-antibody labeling of IgA molecules recognizing HCV peptide epitopes
US7939715B2 (en) 2000-11-16 2011-05-10 Mendel Biotechnology, Inc. Plants with improved yield and stress tolerance
US7098383B2 (en) * 2000-12-19 2006-08-29 Sembiosys Genetics Inc. Methods for the production of multimeric immunoglobulins, and related compositions
NZ526822A (en) * 2000-12-19 2005-03-24 Sembiosys Genetics Inc Methods for the production of multimeric proteins for producing an oil body associated with a recombinant protein complex preferably thioredoxin or an immunoglobin, in transgenic plants and their use in compositons for reducing allergenicity of food
US20030167524A1 (en) * 2000-12-19 2003-09-04 Rooijen Gijs Van Methods for the production of multimeric protein complexes, and related compositions
US20060179514A1 (en) * 2001-07-05 2006-08-10 Sembiosys Genetics, Inc. Methods for the production of multimeric protein complexes, and related compositions
US8426678B2 (en) 2002-09-18 2013-04-23 Mendel Biotechnology, Inc. Polynucleotides and polypeptides in plants
US7255867B2 (en) * 2002-11-15 2007-08-14 Id Biomedical Corporation Of Quebec Vaccine
WO2004076634A2 (en) * 2003-02-24 2004-09-10 Ira Sanders Cell membrane translocation of regulated snare inhibitors , compositions therefor, and methods for treatment of disease
JP2005112827A (ja) * 2003-10-10 2005-04-28 National Institute Of Advanced Industrial & Technology 抗体アフィニティ担体
US20070275873A1 (en) * 2004-04-29 2007-11-29 Heidner Hans W Methods and Compositions Comprising Protein L Immunoglobulin Binding Domains for Cell-Specific Targeting
US8221998B2 (en) * 2005-05-20 2012-07-17 Glaxosmithkline Llc Expression of protein GB1 domain fusion proteins in mammalian cells
WO2008020823A2 (en) * 2005-05-23 2008-02-21 University Of Hawaii Cooperative reporter systems, components, and methods for analyte detection
US10822396B2 (en) * 2009-12-15 2020-11-03 MuHyeon CHOE Repeat-chain for the production of dimer, multimer, multimer complex and super-complex
PL2771364T3 (pl) * 2011-10-27 2020-01-31 Genmab A/S Wytwarzanie heterodimerycznych białek
CA2917721C (en) * 2013-05-30 2023-03-14 Muhyeon Choe Super-complex formed by cross-binding between complexes of repeating chain and monomer and use thereof
US9569513B1 (en) * 2013-09-10 2017-02-14 Amazon Technologies, Inc. Conditional master election in distributed databases
JP6731345B2 (ja) 2014-08-28 2020-07-29 株式会社カネカ 免疫グロブリンｇ結合性ペプチド
JP6369807B2 (ja) * 2014-10-21 2018-08-08 株式会社プロテイン・エクスプレス プロテインｌ変異体
CN107108700B (zh) * 2014-12-17 2023-02-17 思拓凡生物工艺研发有限公司 修饰的κ轻链-结合多肽
JPWO2016121701A1 (ja) * 2015-01-26 2017-11-09 株式会社カネカ 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス
EP3252158A4 (de) 2015-01-26 2018-07-18 Kaneka Corporation Mutantes immunglobulin-kappa-ketten-bindendes protein mit variabler region
WO2017191747A1 (ja) * 2016-05-06 2017-11-09 株式会社カネカ κ鎖可変領域を含むタンパク質の製造方法
WO2017195638A1 (ja) 2016-05-09 2017-11-16 株式会社カネカ 抗体またはκ鎖可変領域含有抗体断片の精製方法
JP6983419B2 (ja) * 2017-02-08 2021-12-17 国立大学法人東京工業大学 抗原検出又は測定用キット
EP4110944A1 (de) 2020-06-12 2023-01-04 New England Biolabs, Inc. Zusammensetzungen und verfahren zum nachweis molekularer targets auf chromosomaler dna
US20240369570A1 (en) * 2021-04-09 2024-11-07 Stichting Radboud Universiteit Off the shelf proximity biotinylation enzyme
GB202112386D0 (en) 2021-08-31 2021-10-13 Cytiva Bioprocess R & D Ab Modified kappa light chain-binding polypeptides
GB202203640D0 (en) 2022-03-16 2022-04-27 Cytiva Bioprocess R & D Ab Alkali-stabilized kappa light chain-binding separation matrix
AU2023288640A1 (en) 2022-06-22 2024-12-12 Cytiva Bioprocess R&D Ab Kappa light chain-binding convection matrix
WO2024165378A2 (en) 2023-02-06 2024-08-15 Cytiva Bioprocess R&D Ab Optimization of elution conditions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE459503B (sv) * 1985-05-03 1989-07-10 Excorim Kommanditbolag Hybrid-dna-molekyl innefattande dna-sekvens som kodar foer protein g samt foerfarande foer framstaellning av protein g
US5312901A (en) 1986-02-14 1994-05-17 Pharmacia Lkb Biotechnology Ab Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G
SE459662B (sv) 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
US4876194A (en) 1986-07-22 1989-10-24 Hightech Receptor Ab Protein L and subfragments thereof, with immunoglobulin binding activity, a process for preparing thereof, reagent kit, pharmaceutical composition and a peptococcus magnus strain
JP2871709B2 (ja) * 1988-11-21 1999-03-17 住友製薬株式会社 免疫グロブリンｇ結合活性を有する新規な蛋白質プロテインｈ、該蛋白質をコードする遺伝子及び該蛋白質の製造法
SE466259B (sv) * 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
SE9002212D0 (sv) * 1990-06-21 1990-06-21 Hightech Receptor Ab Igg binding protein
US5736362A (en) * 1990-10-26 1998-04-07 The University Of Melbourne Ryegrass pollen allergen
SE9201331D0 (sv) * 1992-04-28 1992-04-28 Hightech Receptor C O Active Protein l och hybridproteiner daerav
WO1993022439A1 (en) * 1992-05-07 1993-11-11 Microbiological Research Authority Immunoglobulin binding proteins derived from l protein and their uses
US5977336A (en) * 1993-03-16 1999-11-02 St. Louis University High molecular weight surface proteins of non-typeable haemophilus
AU5874999A (en) * 1998-09-14 2000-04-03 Affitech As Immunoglobulin binding protein
GB9929937D0 (en) * 1999-12-17 2000-02-09 Actinova Ltd Antigen delivery

Also Published As

Publication number Publication date
WO1993022342A1 (en) 1993-11-11
US6822075B2 (en) 2004-11-23
EP0662086A1 (de) 1995-07-12
SE9201331D0 (sv) 1992-04-28
EP0662086B1 (de) 2003-06-11
JP3462209B2 (ja) 2003-11-05
DE69333042T2 (de) 2004-05-06
US5965390A (en) 1999-10-12
JPH07506573A (ja) 1995-07-20
US20030027283A1 (en) 2003-02-06

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Legal Events

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8364 No opposition during term of opposition