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DE69332652D1 - Verbesserungen in bezug auf die herstellung von malariaimpstoffen - Google Patents

Verbesserungen in bezug auf die herstellung von malariaimpstoffen

Info

Publication number
DE69332652D1
DE69332652D1 DE69332652T DE69332652T DE69332652D1 DE 69332652 D1 DE69332652 D1 DE 69332652D1 DE 69332652 T DE69332652 T DE 69332652T DE 69332652 T DE69332652 T DE 69332652T DE 69332652 D1 DE69332652 D1 DE 69332652D1
Authority
DE
Germany
Prior art keywords
pct
production
vectors
sec
malaria vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332652T
Other languages
English (en)
Other versions
DE69332652T2 (de
Inventor
Arthur Holder
John Blackman
Andrew Chappel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research Council filed Critical Medical Research Council
Application granted granted Critical
Publication of DE69332652D1 publication Critical patent/DE69332652D1/de
Publication of DE69332652T2 publication Critical patent/DE69332652T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69332652T 1992-02-22 1993-02-22 Verbesserungen in bezug auf die herstellung von malariaimpstoffen Expired - Lifetime DE69332652T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929203821A GB9203821D0 (en) 1992-02-22 1992-02-22 Improvements in or relating to malaria vaccine
PCT/GB1993/000367 WO1993017107A1 (en) 1992-02-22 1993-02-22 Improvements in or relating to malaria vaccine

Publications (2)

Publication Number Publication Date
DE69332652D1 true DE69332652D1 (de) 2003-02-27
DE69332652T2 DE69332652T2 (de) 2003-11-27

Family

ID=10710868

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332652T Expired - Lifetime DE69332652T2 (de) 1992-02-22 1993-02-22 Verbesserungen in bezug auf die herstellung von malariaimpstoffen

Country Status (13)

Country Link
US (1) US5720959A (de)
EP (1) EP0627004B1 (de)
JP (1) JPH07504321A (de)
KR (1) KR100262624B1 (de)
AT (1) ATE231555T1 (de)
AU (1) AU666519B2 (de)
CA (1) CA2128109C (de)
DE (1) DE69332652T2 (de)
DK (1) DK0627004T3 (de)
ES (1) ES2192556T3 (de)
GB (1) GB9203821D0 (de)
NZ (1) NZ249208A (de)
WO (1) WO1993017107A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697022B1 (fr) 1992-10-19 1994-12-16 Pasteur Institut Antigènes de Plasmodium falciparum capables d'induire des anticorps protecteurs à large spectre - Application à la vaccination.
FR2744724B1 (fr) 1996-02-14 2002-08-02 Pasteur Institut Proteine recombinante contenant un fragment c-terminal de la proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques
CA2337754C (en) 1998-08-21 2011-05-24 Altaf A. Lal Recombinant multivalent malarial vaccine against plasmodium falciparum
WO2001034188A1 (en) 1999-11-12 2001-05-17 University Of Hawaii Malaria vaccine
CN1176945C (zh) * 2001-02-01 2004-11-24 中国人民解放军第二军医大学 疟原虫融合抗原及其制法和用途
US20030104003A1 (en) * 2001-05-25 2003-06-05 James Anthony A. Novel surface protein of the malaria parasite plasmodium falciparum
EP1885395A4 (de) * 2005-05-16 2009-12-02 Merck & Co Inc Verfahren zur verbesserung der immunogenität von plasmodium-antigenen
US7931908B2 (en) 2007-02-23 2011-04-26 Philadelphia Health Education Corporation Chimeric MSP-based malaria vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071705B1 (de) * 1981-05-21 1989-11-23 The Wellcome Foundation Limited Protozoen-Antigen

Also Published As

Publication number Publication date
JPH07504321A (ja) 1995-05-18
AU3570493A (en) 1993-09-13
GB9203821D0 (en) 1992-04-08
DK0627004T3 (da) 2003-05-12
WO1993017107A1 (en) 1993-09-02
CA2128109C (en) 2007-09-25
EP0627004B1 (de) 2003-01-22
AU666519B2 (en) 1996-02-15
ATE231555T1 (de) 2003-02-15
DE69332652T2 (de) 2003-11-27
KR100262624B1 (ko) 2000-08-01
KR950700415A (ko) 1995-01-16
EP0627004A1 (de) 1994-12-07
US5720959A (en) 1998-02-24
NZ249208A (en) 1996-03-26
CA2128109A1 (en) 1993-09-02
ES2192556T3 (es) 2003-10-16

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