DE69310353D1 - 2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze - Google Patents

2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze

Info

Publication number: DE69310353D1
Authority: DE; Germany
Prior art keywords: tetrahydro; benzazepine; acid addition; addition salts; pharmaceutically compatible
Prior art date: 1992-02-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69310353T

Other languages

English (en)

Other versions

DE69310353T2 (de

Inventor

Christian Foged

Rolf Hohlweg

Erik Nielsen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Paion UK Ltd

Original Assignee

Novo Nordisk AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-24

Filing date

1993-02-05

Publication date

1997-06-05

1993-02-05 Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS

1997-06-05 Publication of DE69310353D1 publication Critical patent/DE69310353D1/de

1997-10-02 Application granted granted Critical

1997-10-02 Publication of DE69310353T2 publication Critical patent/DE69310353T2/de

2013-02-06 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DE69310353T 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze Expired - Fee Related DE69310353T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK92233A DK23392D0 (da)	1992-02-24	1992-02-24	Heterocykliske forbindelser, deres anvendelse og fremstilling
PCT/DK1993/000041 WO1993017012A1 (en)	1992-02-24	1993-02-05	2,3,4,5-tetrahydro-1h-3-benzazepines and pharmaceutically acceptable acid addition salts thereof

Publications (2)

Publication Number	Publication Date
DE69310353D1 true DE69310353D1 (de)	1997-06-05
DE69310353T2 DE69310353T2 (de)	1997-10-02

Family

ID=8091236

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69310353T Expired - Fee Related DE69310353T2 (de)	1992-02-24	1993-02-05	2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze

Country Status (23)

Country	Link
EP (1)	EP0628039B1 (de)
JP (1)	JPH07504172A (de)
KR (1)	KR100255739B1 (de)
AT (1)	ATE152450T1 (de)
AU (1)	AU667878B2 (de)
BG (1)	BG62208B1 (de)
CA (1)	CA2130678C (de)
CZ (1)	CZ288626B6 (de)
DE (1)	DE69310353T2 (de)
DK (2)	DK23392D0 (de)
ES (1)	ES2102019T3 (de)
FI (1)	FI113770B (de)
GR (1)	GR3023896T3 (de)
HU (1)	HU221314B1 (de)
IL (1)	IL104657A (de)
NO (1)	NO310193B1 (de)
NZ (1)	NZ249465A (de)
RO (1)	RO116088B1 (de)
RU (1)	RU2114839C1 (de)
SK (1)	SK281390B6 (de)
UA (1)	UA34451C2 (de)
WO (1)	WO1993017012A1 (de)
ZA (1)	ZA931099B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1945495A (en) *	1994-03-16	1995-10-03	Novo Nordisk A/S	Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
HUP9900746A3 (en) *	1995-09-15	1999-11-29	Cenes Ltd Histon	Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds, process for their preparation and pharmaceutical compositions containing the same
GB0130576D0 (en) *	2001-12-20	2002-02-06	Cenes Ltd	Dopamine D1 receptor agonist pro-drug compounds & derivatives
ES2401319T3 (es) *	2002-12-20	2013-04-18	Glaxo Group Limited	Nuevo derivado de benzazepina
EP3842420B1 (de)	2012-10-25	2022-12-07	Tetra Discovery Partners LLC	Heteroaryl-inhibitoren von pde4
US20150086480A1 (en) *	2013-09-26	2015-03-26	Tetra Discovery Partners, LLC	Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK180485D0 (da) *	1985-04-22	1985-04-23	Novo Industri As	Nitrogenholdige forbindelser
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
DK67489D0 (da) *	1989-02-14	1989-02-14	Novo Industri As	Nye benzazepinderivater

1992
- 1992-02-24 DK DK92233A patent/DK23392D0/da not_active Application Discontinuation
1993
- 1993-02-05 CZ CZ19941988A patent/CZ288626B6/cs not_active IP Right Cessation
- 1993-02-05 DE DE69310353T patent/DE69310353T2/de not_active Expired - Fee Related
- 1993-02-05 NZ NZ249465A patent/NZ249465A/en unknown
- 1993-02-05 HU HU9402434A patent/HU221314B1/hu not_active IP Right Cessation
- 1993-02-05 AU AU36265/93A patent/AU667878B2/en not_active Ceased
- 1993-02-05 CA CA002130678A patent/CA2130678C/en not_active Expired - Fee Related
- 1993-02-05 SK SK1000-94A patent/SK281390B6/sk unknown
- 1993-02-05 AT AT93905215T patent/ATE152450T1/de not_active IP Right Cessation
- 1993-02-05 UA UA94085741A patent/UA34451C2/uk unknown
- 1993-02-05 WO PCT/DK1993/000041 patent/WO1993017012A1/en active IP Right Grant
- 1993-02-05 DK DK93905215.5T patent/DK0628039T3/da active
- 1993-02-05 KR KR1019940702944A patent/KR100255739B1/ko not_active Expired - Fee Related
- 1993-02-05 JP JP5514460A patent/JPH07504172A/ja active Pending
- 1993-02-05 EP EP93905215A patent/EP0628039B1/de not_active Expired - Lifetime
- 1993-02-05 RU RU94040719A patent/RU2114839C1/ru not_active IP Right Cessation
- 1993-02-05 RO RO94-01400A patent/RO116088B1/ro unknown
- 1993-02-05 ES ES93905215T patent/ES2102019T3/es not_active Expired - Lifetime
- 1993-02-09 IL IL10465793A patent/IL104657A/en not_active IP Right Cessation
- 1993-02-17 ZA ZA931099A patent/ZA931099B/xx unknown
1994
- 1994-08-22 BG BG98993A patent/BG62208B1/bg unknown
- 1994-08-23 FI FI943875A patent/FI113770B/fi not_active IP Right Cessation
- 1994-08-24 NO NO19943123A patent/NO310193B1/no not_active IP Right Cessation
1997
- 1997-06-26 GR GR970401543T patent/GR3023896T3/el unknown

Also Published As

Publication number	Publication date
GR3023896T3 (en)	1997-09-30
ZA931099B (en)	1994-08-17
ATE152450T1 (de)	1997-05-15
RU2114839C1 (ru)	1998-07-10
NO310193B1 (no)	2001-06-05
DK23392D0 (da)	1992-02-24
BG98993A (bg)	1995-05-31
NO943123L (no)	1994-08-24
CA2130678A1 (en)	1993-08-25
CA2130678C (en)	2004-04-20
IL104657A0 (en)	1993-06-10
HUT71127A (en)	1995-11-28
RU94040719A (ru)	1996-07-10
KR100255739B1 (ko)	2000-05-01
IL104657A (en)	1999-11-30
AU3626593A (en)	1993-09-13
FI113770B (fi)	2004-06-15
DE69310353T2 (de)	1997-10-02
JPH07504172A (ja)	1995-05-11
CZ198894A3 (en)	1995-10-18
ES2102019T3 (es)	1997-07-16
NZ249465A (en)	1996-02-27
KR950700286A (ko)	1995-01-16
RO116088B1 (ro)	2000-10-30
EP0628039A1 (de)	1994-12-14
NO943123D0 (no)	1994-08-24
WO1993017012A1 (en)	1993-09-02
SK281390B6 (sk)	2001-03-12
FI943875L (fi)	1994-08-23
EP0628039B1 (de)	1997-05-02
AU667878B2 (en)	1996-04-18
FI943875A0 (fi)	1994-08-23
DK0628039T3 (da)	1997-12-08
HU9402434D0 (en)	1994-10-28
CZ288626B6 (cs)	2001-08-15
UA34451C2 (uk)	2001-03-15
SK100094A3 (en)	1995-04-12
BG62208B1 (bg)	1999-05-31
HU221314B1 (en)	2002-09-28

Publication	Publication Date	Title
FI941378A0 (fi)	1994-03-24	Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
DE69232334D1 (de)	2002-02-14	Substituierte 3-aminochinuclidine
PH25571A (en)	1991-08-08	Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments
ATE206708T1 (de)	2001-10-15	Benzimidazolonderivate mit zentraler dopaminerger aktivität
FI970469A0 (fi)	1997-02-04	Bentsimidatsolijohdannaisia, joilla on dopaminerginen aktiivisuus
DE69310353D1 (de)	1997-06-05	2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze
TW349864B (en)	1999-01-11	Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders
FI865220A0 (fi)	1986-12-19	Foerfarande foer framstaellning av sulfinyl- och sulfonylsubstituerade 3-benzazepiner.
ATE89553T1 (de)	1993-06-15	Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.

Legal Events

Date	Code	Title	Description
1998-05-28	8364	No opposition during term of opposition
2001-02-15	8327	Change in the person/name/address of the patent owner	Owner name: CENES LTD., CAMBRIDGE, GB
2005-12-15	8339	Ceased/non-payment of the annual fee