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DE69232034D1 - Aerosol compositions for drug suspensions - Google Patents

Aerosol compositions for drug suspensions

Info

Publication number
DE69232034D1
DE69232034D1 DE69232034T DE69232034T DE69232034D1 DE 69232034 D1 DE69232034 D1 DE 69232034D1 DE 69232034 T DE69232034 T DE 69232034T DE 69232034 T DE69232034 T DE 69232034T DE 69232034 D1 DE69232034 D1 DE 69232034D1
Authority
DE
Germany
Prior art keywords
aerosol compositions
drug suspensions
aerosol formulation
suspensions
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69232034T
Other languages
German (de)
Other versions
DE69232034T2 (en
Inventor
Robert K Schultz
David W Schultz
Martin J Oliver
Robert A Moris
Philip A Jinks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69232034(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Publication of DE69232034D1 publication Critical patent/DE69232034D1/en
Application granted granted Critical
Publication of DE69232034T2 publication Critical patent/DE69232034T2/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)

Abstract

A pharmaceutical suspension aerosol formulation consisting of a therapeutically effective amount of micronised albuterol sulphate, propellant selected from HFC134a, HFC 227 and mixtures thereof and ethanol in an amount of from 5 to 15% by weight of the aerosol formulation.
DE69232034T 1991-12-18 1992-12-11 Aerosol compositions for drug suspensions Revoked DE69232034T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80979191A 1991-12-18 1991-12-18
US81040191A 1991-12-18 1991-12-18
US87803992A 1992-05-04 1992-05-04

Publications (2)

Publication Number Publication Date
DE69232034D1 true DE69232034D1 (en) 2001-10-04
DE69232034T2 DE69232034T2 (en) 2002-06-06

Family

ID=27420051

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69218455T Revoked DE69218455T2 (en) 1991-12-18 1992-12-11 AEROSOL COMPOSITIONS FOR MEDICAL SUSPENSIONS
DE69232034T Revoked DE69232034T2 (en) 1991-12-18 1992-12-11 Aerosol compositions for drug suspensions
DE69233319T Expired - Lifetime DE69233319T2 (en) 1991-12-18 1992-12-11 Aerosol compositions for drug suspensions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69218455T Revoked DE69218455T2 (en) 1991-12-18 1992-12-11 AEROSOL COMPOSITIONS FOR MEDICAL SUSPENSIONS

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69233319T Expired - Lifetime DE69233319T2 (en) 1991-12-18 1992-12-11 Aerosol compositions for drug suspensions

Country Status (13)

Country Link
US (2) US6743413B1 (en)
EP (3) EP1086688B1 (en)
JP (2) JP3908269B2 (en)
AT (3) ATE150296T1 (en)
AU (2) AU675633B2 (en)
CA (2) CA2320129C (en)
DE (3) DE69218455T2 (en)
DK (3) DK1086688T3 (en)
ES (3) ES2159678T3 (en)
GR (2) GR3022874T3 (en)
NZ (1) NZ246421A (en)
PT (2) PT717987E (en)
WO (1) WO1993011747A1 (en)

Families Citing this family (121)

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US20040197273A1 (en) 2004-10-07
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CA2320129A1 (en) 1993-06-24
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