[go: up one dir, main page]

DE69128308D1 - Verfahren zur Herstellung von Hefe-Glucanen - Google Patents

Verfahren zur Herstellung von Hefe-Glucanen

Info

Publication number
DE69128308D1
DE69128308D1 DE69128308T DE69128308T DE69128308D1 DE 69128308 D1 DE69128308 D1 DE 69128308D1 DE 69128308 T DE69128308 T DE 69128308T DE 69128308 T DE69128308 T DE 69128308T DE 69128308 D1 DE69128308 D1 DE 69128308D1
Authority
DE
Germany
Prior art keywords
provides
stimulating
administering
glucan
immune system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69128308T
Other languages
English (en)
Other versions
DE69128308T2 (de
Inventor
Gunnar Rorstad
Borre Robertson
Jan Raa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arcticzymes Technologies ASA
Original Assignee
Biotec Mackzymal ASA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotec Mackzymal ASA filed Critical Biotec Mackzymal ASA
Application granted granted Critical
Publication of DE69128308D1 publication Critical patent/DE69128308D1/de
Publication of DE69128308T2 publication Critical patent/DE69128308T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69128308T 1990-07-06 1991-07-04 Verfahren zur Herstellung von Hefe-Glucanen Expired - Lifetime DE69128308T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54957590A 1990-07-06 1990-07-06

Publications (2)

Publication Number Publication Date
DE69128308D1 true DE69128308D1 (de) 1998-01-15
DE69128308T2 DE69128308T2 (de) 1998-03-26

Family

ID=24193557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69128308T Expired - Lifetime DE69128308T2 (de) 1990-07-06 1991-07-04 Verfahren zur Herstellung von Hefe-Glucanen

Country Status (12)

Country Link
US (1) US5401727A (de)
EP (1) EP0466037B1 (de)
JP (1) JP2828799B2 (de)
AT (1) ATE160787T1 (de)
AU (1) AU628752B2 (de)
CA (1) CA2040374C (de)
DE (1) DE69128308T2 (de)
DK (1) DK0466037T3 (de)
ES (1) ES2109929T3 (de)
FI (1) FI104537B (de)
GR (1) GR3026130T3 (de)
NO (1) NO305705B1 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665649B2 (ja) * 1991-02-01 1994-08-24 台糖株式会社 甲殻類の生体防御能増強剤、感染症予防ワクチン及び飼料
JP3522772B2 (ja) * 1991-05-21 2004-04-26 台糖株式会社 ワクチンの免疫効果増強剤
EP0640348A1 (de) * 1993-07-26 1995-03-01 Akzo Nobel N.V. Adjuvansmischung auf Ölbasis und auf Wasserbasis
PL177628B1 (pl) * 1993-08-06 1999-12-31 As Biotec Mackzymal Kompozycja paszy zwierzęcej
JPH08113539A (ja) * 1993-09-22 1996-05-07 Nippon Paper Ind Co Ltd 免疫増強剤及びその製造方法、並びにそれを用いた甲殻類及び魚類の養殖用飼料
NO300692B1 (no) * 1994-04-29 1997-07-07 Biotec Mackzymal As Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan
US5871751A (en) * 1994-10-12 1999-02-16 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Renibacterium salmoninarum vaccine and method for its preparation
JP3744020B2 (ja) * 1995-04-14 2006-02-08 日本製紙株式会社 免疫増強剤並びにそれを含有する甲殻類、魚類及び家畜用飼料
PT848592E (pt) * 1995-09-05 2001-03-30 Baensch Tetra Werke Agentes anti-"stress" para animais aquaticos
US5722346A (en) * 1996-04-17 1998-03-03 The Board Of Governors For Higher Education Smolting feed
US5786343A (en) * 1997-03-05 1998-07-28 Immudyne, Inc. Phagocytosis activator compositions and their use
AU6691598A (en) * 1997-04-18 1998-11-13 Immudyne, Inc. Gel delivery system for animal nutrition and health
WO2000015238A1 (en) * 1998-09-14 2000-03-23 Nabi COMPOSITIONS OF β-GLUCANS AND SPECIFIC IGIV
US7030101B2 (en) 1998-09-14 2006-04-18 Nabi Biopharmaceuticals Compositions of β-glucans and specific antibodies
US20020009463A1 (en) * 2000-02-23 2002-01-24 Jan Raa Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces
US20040127458A1 (en) * 2000-11-06 2004-07-01 Hunter Kenneth W. Beta-glucan containing compositions, methods for manufacturing beta-glucans, and for manufacturing and using beta-glucans and conjugates thereof as vaccine adjuvants
US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
US7816514B2 (en) 2001-02-16 2010-10-19 Cargill, Incorporated Glucosamine and method of making glucosamine from microbial biomass
US7923437B2 (en) * 2001-02-16 2011-04-12 Cargill, Incorporated Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
US7323140B2 (en) * 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US6939864B1 (en) 2001-07-09 2005-09-06 Purdue Research Foundation Animal feed compositions and methods of using the same
US20040248772A1 (en) * 2001-11-06 2004-12-09 Akikuni Yagita Anticancer compositions
DE10222358A1 (de) * 2002-05-21 2003-12-11 Nutrinova Gmbh ß-Glucanhaltiges Sorbinsäurepräparat als Futtermittelzusatz in der Nutztieraufzucht
US7018986B2 (en) * 2002-09-20 2006-03-28 Immudyne Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption
GB0225502D0 (en) * 2002-11-01 2002-12-11 Zoolife Internat Ltd Therapeutic and prophylactic preparations
GB0225503D0 (en) * 2002-11-01 2002-12-11 Zoolife Internat Ltd Gel feed
JP2004210895A (ja) * 2002-12-27 2004-07-29 Immudyne Japan:Kk 免疫機能を有する可能性β−グルカンの製造方法及び用途
EP1594418A2 (de) * 2003-01-29 2005-11-16 Immudyne, Inc. Immunstimulierender wirkstoff zur verwendung bei tieren
GB2399752A (en) * 2003-03-26 2004-09-29 Micap Plc Pharmaceutical composition comprising a fungal cell or cell fragment as adjuvant
SI1711058T1 (sl) 2004-01-23 2022-02-28 Eden Research Plc, Postopki za uničevanje nematod, ki obsega uporabo terpenske komponente
CN1997446B (zh) 2004-05-20 2012-01-04 伊顿研究有限公司 含有包封萜成分的中空葡聚糖颗粒或细胞壁颗粒的组合物、其制备和使用方法
US7740861B2 (en) * 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
EP1802289B1 (de) * 2004-09-17 2011-12-07 University of Massachusetts Zusammensetzungen und ihre verwendungen bei lysosomalen enzymstörungen
US7306818B2 (en) * 2005-01-03 2007-12-11 Promd Biotech Co., Ltd. Method for preventing and/or treating viral infection in aquatic animals
EP1877447B1 (de) 2005-05-05 2016-12-21 Sensient Flavors Inc. Herstellung von betaglukanen und mannanen
WO2007050643A2 (en) * 2005-10-24 2007-05-03 University Of Massachusetts Compositions and their uses for gene therapy of bone conditions
EP2982244B1 (de) 2005-11-30 2020-11-18 Eden Research Plc Thymolhaltige Insektizide Kapseln und Verfahren zu ihrer Herstellung und Verwendung
US9439416B2 (en) 2005-11-30 2016-09-13 Eden Research Plc Compositions and methods comprising terpenes or terpene mixtures selected from thymol, eugenol, geraniol, citral, and l-carvone
TW200900053A (en) * 2007-02-21 2009-01-01 Biotec Pharmacon Asa Medical uses of glucans
JP5153188B2 (ja) * 2007-03-30 2013-02-27 小林製薬株式会社 Th1/Th2バランス改善剤
US20090061049A1 (en) * 2007-08-28 2009-03-05 Vadood Azarm Feed compositions for aquatic animals and methods of making the same
JP2011517279A (ja) * 2007-10-29 2011-06-02 ユニバーシティ オブ マサチューセッツ 核酸(siRNA)送達用の酵母細胞壁粒子(YCWP)多層状ナノ粒子
AU2008322737A1 (en) * 2007-11-13 2009-05-22 Biotec Pharmacon Asa Methods of treating or preventing inflammatory diseases of the intestinal tract
WO2009067020A1 (en) 2007-11-19 2009-05-28 Calanus As Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites
US8815818B2 (en) 2008-07-18 2014-08-26 Rxi Pharmaceuticals Corporation Phagocytic cell delivery of RNAI
WO2010078536A1 (en) 2009-01-05 2010-07-08 Rxi Pharmaceuticals Corporation Inhibition of pcsk9 through rnai
US20100267661A1 (en) * 2009-03-17 2010-10-21 Immudyne, Inc. Beta glucans and methods of use thereof
KR20180044433A (ko) 2010-03-24 2018-05-02 알엑스아이 파마슈티칼스 코포레이션 진피 및 섬유증성 적응증에서의 rna 간섭
CA2794187C (en) 2010-03-24 2020-07-14 Rxi Pharmaceuticals Corporation Rna interference in ocular indications
ES2614181T3 (es) 2010-08-14 2017-05-30 University Of Massachusetts Partícula de pared celular de levadura para suministro de nanopartículas direccionadas al receptor
EP2694030A2 (de) 2011-03-04 2014-02-12 Sana Pharma AS Kosmetische formulierungen
GB201220940D0 (en) 2012-11-21 2013-01-02 Eden Research Plc Method P
AP2016009288A0 (en) 2013-11-21 2016-06-30 Eden Research Plc Pesticidal composition
CN105960265A (zh) 2013-12-04 2016-09-21 阿克赛医药公司 利用经化学修饰的寡核苷酸处理伤口愈合的方法
EP3137119B1 (de) 2014-04-28 2020-07-01 Phio Pharmaceuticals Corp. Verfahren zur behandlung von krebs mithilfe von einer nukleinsaüre gegen mdm2
US20170051290A1 (en) 2014-05-01 2017-02-23 Rxi Pharmaceuticals Corporation Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules
JP6836987B2 (ja) 2014-09-05 2021-03-03 フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. Tyrまたはmmp1を標的とする核酸を用いて老化および皮膚障害を処置するための方法
US20170369872A1 (en) 2014-12-18 2017-12-28 Alnylam Pharmaceuticals, Inc. Reversir tm compounds
GB201501793D0 (en) 2015-02-03 2015-03-18 Eden Research Plc Encapsulation of high potency active agents
US11001845B2 (en) 2015-07-06 2021-05-11 Phio Pharmaceuticals Corp. Nucleic acid molecules targeting superoxide dismutase 1 (SOD1)
WO2017007825A1 (en) 2015-07-06 2017-01-12 Rxi Pharmaceuticals Corporation Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
EP3138573A1 (de) * 2015-07-09 2017-03-08 Danstar Ferment AG Zusammensetzungen und verfahren zur stimulation der immunantwort in menschen und/oder tieren
CN109563509B (zh) 2015-10-19 2022-08-09 菲奥医药公司 靶向长非编码rna的减小尺寸的自递送核酸化合物
CN106719136A (zh) * 2016-11-30 2017-05-31 蚌埠市渔歌农业科技有限公司 一种防治鲶鱼病害的养殖方法
JP6530846B1 (ja) * 2018-10-09 2019-06-12 アサヒグループホールディングス株式会社 免疫賦活剤及び感染予防方法
CN115135765A (zh) 2019-11-08 2022-09-30 菲奥医药公司 用于免疫治疗的靶向含布罗莫结构域之蛋白4(brd4)的经化学修饰的寡核苷酸
KR20240011139A (ko) * 2021-05-21 2024-01-25 아사히 그룹 홀딩스 가부시키가이샤 면역 부활제 및 글루칸 조성물의 제조 방법
TW202449152A (zh) 2023-02-09 2024-12-16 美商艾拉倫製藥股份有限公司 Reversir分子及其使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3301848A (en) * 1962-10-30 1967-01-31 Pillsbury Co Polysaccharides and methods for production thereof
GB2076418A (en) * 1980-05-22 1981-12-02 Sankyo Co Hydrolyzed polysaccharide
SE456911B (sv) * 1983-12-19 1988-11-14 Olle Larm Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma
JPS6120561A (ja) * 1984-07-09 1986-01-29 住友ベークライト株式会社 医療用吸着剤
US4810646A (en) * 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US4739046A (en) * 1985-08-19 1988-04-19 Luzio Nicholas R Di Soluble phosphorylated glucan
JPS6337801A (ja) * 1986-07-31 1988-02-18 Matsushita Electric Ind Co Ltd タ−ンテ−ブル
CA1330303C (en) * 1989-02-20 1994-06-21 Libor Henry Nikl Composition and process to enhance the efficacy of a fish vaccine

Also Published As

Publication number Publication date
EP0466037A2 (de) 1992-01-15
EP0466037A3 (en) 1992-10-28
ES2109929T3 (es) 1998-02-01
CA2040374C (en) 1998-06-16
NO912645L (no) 1992-01-07
JP2828799B2 (ja) 1998-11-25
AU628752B2 (en) 1992-09-17
CA2040374A1 (en) 1992-01-07
EP0466037B1 (de) 1997-12-03
DE69128308T2 (de) 1998-03-26
JPH04253703A (ja) 1992-09-09
FI913275L (fi) 1992-01-07
FI104537B (fi) 2000-02-29
GR3026130T3 (en) 1998-05-29
US5401727A (en) 1995-03-28
AU7933891A (en) 1992-01-23
NO305705B1 (no) 1999-07-12
FI913275A0 (fi) 1991-07-05
DK0466037T3 (da) 1998-08-10
ATE160787T1 (de) 1997-12-15
NO912645D0 (no) 1991-07-05

Similar Documents

Publication Publication Date Title
DE69128308D1 (de) Verfahren zur Herstellung von Hefe-Glucanen
DE69637481D1 (de) Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
CA2033640A1 (en) Vaccines against cancer and infectious diseases
AU7814498A (en) Multivalent (in ovo) avian vaccine
DE69836268D1 (de) Immunverstärkende Zusammensetzung in fester Verabreichungsform mit Kollagen oder Polydimethylsiloxan als Trägersubstanzen
ATE150976T1 (de) Impfstoff-konjugate zur behandlung von vogelkrankheiten
BR9713312B1 (pt) preparado de vacina para uso veterinário útil para produzir imunidade ativa contra uma doença bacteriana ou protozoária.
EP0716613A4 (de) BEHANDLUNG EINES DURCH -i(HELICOBAKTER PYLORI) VERURSACHTEN GASTRODUODENALEN KRANKHEIT
DE69030099D1 (de) Verfahren zur herstellung von impfstoffen oder toxoiden
DE69333730D1 (de) Impfstoff, der acemannan als adjuvans enthält
EP0254845A3 (de) Immun-Stimulation mit Chondroitin-sulfat
DE68917138D1 (de) Toleranzinduktion gegenüber einem fremdantigen.
DE69429521D1 (de) Zusammensetzung und verfahren zur stimulation der reproduzierenden leistung
PT636030E (pt) Vacina de bacterina-toxoide de pasteurella haemolytica tipo a-1
ATE39055T1 (de) Verfahren zur immunisierung von schweinen gegen die aujeszky-krankheit.
PT87001A (pt) Processo para a preparacao de uma vacina contra a disenteria suina e fins analogos
PL341541A1 (en) Isolated strains of staphyloccoccus aureus and vaccines prepared of them
Birnbaum et al. Local and systemic opsonic adherent, hemagglutinating and rosette forming activity in mice induced by respiratory immunization with sheep red blood cells
ATE145335T1 (de) Kreuzreaktive immunisierung gegen influenza

Legal Events

Date Code Title Description
8364 No opposition during term of opposition