[go: up one dir, main page]

DE69031914D1 - Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate - Google Patents

Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate

Info

Publication number
DE69031914D1
DE69031914D1 DE69031914T DE69031914T DE69031914D1 DE 69031914 D1 DE69031914 D1 DE 69031914D1 DE 69031914 T DE69031914 T DE 69031914T DE 69031914 T DE69031914 T DE 69031914T DE 69031914 D1 DE69031914 D1 DE 69031914D1
Authority
DE
Germany
Prior art keywords
csf
receptor
derivatives
macrophage colony
granulocyte macrophage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69031914T
Other languages
English (en)
Other versions
DE69031914T2 (de
Inventor
Nicos Nicola
Nicholas Gough
David Gearing
Donald Metcalf
Julie King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Innovation Pty Ltd
Original Assignee
Amrad Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amrad Corp Ltd filed Critical Amrad Corp Ltd
Publication of DE69031914D1 publication Critical patent/DE69031914D1/de
Application granted granted Critical
Publication of DE69031914T2 publication Critical patent/DE69031914T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69031914T 1989-08-11 1990-08-10 Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate Expired - Lifetime DE69031914T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPJ574389 1989-08-11
AUPK001490 1990-05-08
PCT/AU1990/000342 WO1991002063A1 (en) 1989-08-11 1990-08-10 Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof

Publications (2)

Publication Number Publication Date
DE69031914D1 true DE69031914D1 (de) 1998-02-12
DE69031914T2 DE69031914T2 (de) 1998-07-30

Family

ID=25643733

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69031914T Expired - Lifetime DE69031914T2 (de) 1989-08-11 1990-08-10 Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate

Country Status (10)

Country Link
US (2) US5726036A (de)
EP (1) EP0486572B1 (de)
JP (1) JP3267966B2 (de)
AT (1) ATE161883T1 (de)
AU (1) AU637133B2 (de)
CA (1) CA2064814C (de)
DE (1) DE69031914T2 (de)
DK (1) DK0486572T3 (de)
SG (1) SG59954A1 (de)
WO (1) WO1991002063A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747032A (en) * 1990-08-10 1998-05-05 Amrad Corporation Limited Monoclonal antibody to human granulocyte macrophage colony stimulating factor
AU673858B2 (en) * 1992-10-09 1996-11-28 Amrad Operations Pty. Limited Monoclonal antibody
EP0673389A1 (de) * 1992-11-19 1995-09-27 Dana Farber Cancer Institute Antikörper gegen den gm-csf rezeptor und dessen verwendung
AU734090B2 (en) * 1996-09-10 2001-06-07 Millennium Pharmaceuticals, Inc. CXCR3 chemokine receptor, antibodies, nucleic acids, and methods of use
US6140064A (en) 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
AU2074101A (en) * 1999-12-08 2001-06-18 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
US7247618B2 (en) * 2001-04-30 2007-07-24 Tripathi Rajavashisth Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
WO2005038055A1 (en) * 2003-09-22 2005-04-28 Nathaniel Tue Tran Multiplexing array techniques
EP2423229B1 (de) * 2006-03-27 2013-05-08 Medimmune Limited Bindeelement für den GM-CSF-Rezeptor
RU2712273C2 (ru) 2008-12-22 2020-01-28 Де Юниверсити Оф Мельбурн Лечение остеоартрита
ES2978209T3 (es) 2008-12-22 2024-09-09 Univ Melbourne Tratamiento del dolor
EP2470212A4 (de) * 2009-10-01 2013-12-04 Csl Ltd Verfahren zur behandlung von philadelphia-chromosom-positiver leukämie
EP2780363B1 (de) 2011-11-17 2019-07-03 Glia SP Z.O.O. Zusammensetzungen und verfahren zur behandlung eines glioms
DK2932264T3 (da) 2012-12-14 2019-05-06 Biontech Rna Pharmaceuticals Gmbh Nye MHC-uafhængige tumor-associerede antigener
EP4219530A1 (de) 2014-12-05 2023-08-02 City of Hope Auf cs1-abzielende chimärische antigenrezeptormodifizierte t-zellen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
US5109119A (en) * 1989-06-06 1992-04-28 Schering Corporation Crystalline r-h-gm-csf and method
US5112961A (en) * 1990-07-18 1992-05-12 Schering Corporation Dna encoding subunits of a high affinity gm-csf receptor

Also Published As

Publication number Publication date
EP0486572B1 (de) 1998-01-07
SG59954A1 (en) 1999-02-22
ATE161883T1 (de) 1998-01-15
JP3267966B2 (ja) 2002-03-25
US5726036A (en) 1998-03-10
DK0486572T3 (da) 1998-05-04
CA2064814A1 (en) 1991-02-12
EP0486572A1 (de) 1992-05-27
AU637133B2 (en) 1993-05-20
AU6189690A (en) 1991-03-11
JPH04507344A (ja) 1992-12-24
EP0486572A4 (en) 1993-05-05
DE69031914T2 (de) 1998-07-30
CA2064814C (en) 2004-06-08
WO1991002063A1 (en) 1991-02-21
US6136957A (en) 2000-10-24

Similar Documents

Publication Publication Date Title
DE69031914D1 (de) Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate
Nilsson et al. Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB
Li et al. Constitutive expression of growth regulated oncogene (gro) in human colon carcinoma cells with different metastatic potential and its role in regulating their metastatic phenotype
Hwang et al. CXC chemokine receptor 4 expression and function in human anaplastic thyroid cancer cells
Wolf et al. Granulocyte chemotactic protein 2 acts via both IL‐8 receptors, CXCR1 and CXCR2
Johnston et al. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
Kelso et al. Secretion of interleukin 2, macrophage-activating factor, interferon, and colony-stimulating factor by alloreactive T lymphocyte clones.
DE60009533T2 (de) Multiple analyse von zytokinen
US6028176A (en) High-affinity interleukin-4 muteins
ATE273384T1 (de) Tie-2 liganden, herstellungsverfahren und verwendung
CA2078118A1 (en) Cc-1065 analogs
FI971406A0 (fi) TIE-2-ligandeja ja menetelmiä niiden valmistamiseksi ja käyttämiseksi
DK0673420T3 (da) Mammale receptorer for interleukin 10 (IL-10)
Glimm et al. Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor–1 enhances their ability to engraft NOD/SCID mice
Chin et al. Identification of a high-affinity receptor for interleukin 1 alpha and interleukin 1 beta on cultured human rheumatoid synovial cells.
KR920000789A (ko) 면역글로불린 부분을 갖는 융합 단백질, 이의 제조방법 및 용도
DE69232309D1 (de) Weitgehend reine rezeptorartige, tgf-beta-1-bindende moleküle und deren verwendungen
Culouscou et al. Biochemical analysis of the epithelin receptor
MAGRANGEAS et al. Negative cross-talk between interleukin-3 and interleukin-11 is mediated by suppressor of cytokine signalling-3 (SOCS-3)
Schraufstatter et al. Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages
Myers et al. Growth stimulation of human head and neck squamous cell carcinoma cell lines by interleukin 4.
ATE70280T1 (de) Charakteristische polypeptide und antikoerper vom papillomavirus, diagnostische verfahren und dieselben verwendende impfungen.
CN1191606A (zh) BL3造血干细胞上的糖蛋白gp105
CA2218372C (en) Antagonists of human interleukin-6 that are totally incapable of binding gp 130, and their use in the preparation of pharmaceutical compounds
Azam et al. Identification of a critical Ig-like domain in IL-18 receptor α and characterization of a functional IL-18 receptor complex

Legal Events

Date Code Title Description
8364 No opposition during term of opposition