[go: up one dir, main page]

ATE161883T1 - Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate - Google Patents

Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate

Info

Publication number
ATE161883T1
ATE161883T1 AT90912329T AT90912329T ATE161883T1 AT E161883 T1 ATE161883 T1 AT E161883T1 AT 90912329 T AT90912329 T AT 90912329T AT 90912329 T AT90912329 T AT 90912329T AT E161883 T1 ATE161883 T1 AT E161883T1
Authority
AT
Austria
Prior art keywords
csf
receptor
derivatives
stimulating factor
macrophage colony
Prior art date
Application number
AT90912329T
Other languages
English (en)
Inventor
Nicos Anthony Nicola
Nicholas Martin Gough
David Paul Gearing
Donald Metcalf
Julie Ann King
Original Assignee
Amrad Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amrad Corp Ltd filed Critical Amrad Corp Ltd
Application granted granted Critical
Publication of ATE161883T1 publication Critical patent/ATE161883T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT90912329T 1989-08-11 1990-08-10 Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate ATE161883T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPJ574389 1989-08-11
AUPK001490 1990-05-08

Publications (1)

Publication Number Publication Date
ATE161883T1 true ATE161883T1 (de) 1998-01-15

Family

ID=25643733

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90912329T ATE161883T1 (de) 1989-08-11 1990-08-10 Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate

Country Status (10)

Country Link
US (2) US5726036A (de)
EP (1) EP0486572B1 (de)
JP (1) JP3267966B2 (de)
AT (1) ATE161883T1 (de)
AU (1) AU637133B2 (de)
CA (1) CA2064814C (de)
DE (1) DE69031914T2 (de)
DK (1) DK0486572T3 (de)
SG (1) SG59954A1 (de)
WO (1) WO1991002063A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009149A1 (en) * 1990-08-10 1994-04-28 Amrad Corporation Limited Monoclonal antibody
AU673858B2 (en) * 1992-10-09 1996-11-28 Amrad Operations Pty. Limited Monoclonal antibody
AU5611394A (en) * 1992-11-19 1994-06-08 Dana-Farber Cancer Institute Antibodies for gm-csf receptor and uses thereof
US6140064A (en) 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
EP0925358B1 (de) * 1996-09-10 2007-04-25 Theodor-Kocher Institute Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung
US20020009724A1 (en) * 1999-12-08 2002-01-24 Robert Schlegel Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
US7247618B2 (en) * 2001-04-30 2007-07-24 Tripathi Rajavashisth Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
WO2005038055A1 (en) * 2003-09-22 2005-04-28 Nathaniel Tue Tran Multiplexing array techniques
CN101443360B (zh) * 2006-03-27 2013-11-27 医学免疫有限公司 Gm-csf受体结合元件
KR101799264B1 (ko) 2008-12-22 2017-11-20 더 유니버시티 오브 멜버른 골관절염 치료
US8475796B2 (en) 2008-12-22 2013-07-02 University Of Melbourne Method of treating pain using an antagonist of GM-CSF
CA2775155A1 (en) * 2009-10-01 2011-04-07 Csl Limited Method of treatment of philadelphia chromosome positive leukemia
CA2856329A1 (en) 2011-11-17 2013-05-23 Nencki Institute Of Experimental Biology Compositions and methods for treating glioma
DK2932264T3 (da) * 2012-12-14 2019-05-06 Biontech Rna Pharmaceuticals Gmbh Nye MHC-uafhængige tumor-associerede antigener
CA2969704C (en) 2014-12-05 2023-05-02 City Of Hope Cs1 targeted chimeric antigen receptor-modified t cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
US5109119A (en) * 1989-06-06 1992-04-28 Schering Corporation Crystalline r-h-gm-csf and method
US5112961A (en) * 1990-07-18 1992-05-12 Schering Corporation Dna encoding subunits of a high affinity gm-csf receptor

Also Published As

Publication number Publication date
EP0486572A4 (en) 1993-05-05
SG59954A1 (en) 1999-02-22
DE69031914T2 (de) 1998-07-30
AU637133B2 (en) 1993-05-20
JP3267966B2 (ja) 2002-03-25
DK0486572T3 (da) 1998-05-04
CA2064814A1 (en) 1991-02-12
EP0486572B1 (de) 1998-01-07
CA2064814C (en) 2004-06-08
US6136957A (en) 2000-10-24
DE69031914D1 (de) 1998-02-12
AU6189690A (en) 1991-03-11
WO1991002063A1 (en) 1991-02-21
JPH04507344A (ja) 1992-12-24
EP0486572A1 (de) 1992-05-27
US5726036A (en) 1998-03-10

Similar Documents

Publication Publication Date Title
ATE161883T1 (de) Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate
Wolpe et al. Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines
Nilsson et al. Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB
Giri et al. Identification and cloning of a novel IL‐15 binding protein that is structurally related to the alpha chain of the IL‐2 receptor.
Wuyts et al. Characterization of synthetic human granulocyte chemotactic protein 2: usage of chemokine receptors CXCR1 and CXCR2 and in vivo inflammatory properties
Wolf et al. Granulocyte chemotactic protein 2 acts via both IL‐8 receptors, CXCR1 and CXCR2
Prystowsky et al. Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes.
Hwang et al. CXC chemokine receptor 4 expression and function in human anaplastic thyroid cancer cells
Kelso et al. Secretion of interleukin 2, macrophage-activating factor, interferon, and colony-stimulating factor by alloreactive T lymphocyte clones.
DE60009533T2 (de) Multiple analyse von zytokinen
ATE273384T1 (de) Tie-2 liganden, herstellungsverfahren und verwendung
Chin et al. Identification of a high-affinity receptor for interleukin 1 alpha and interleukin 1 beta on cultured human rheumatoid synovial cells.
FI875732A (fi) Elektrokemoluminescens- analysfoerfaranden.
Mergenhagen Thymocyte activating factor (s) in human gingival fluids
DK0673420T3 (da) Mammale receptorer for interleukin 10 (IL-10)
DE69637155D1 (de) Addressine der schleimhaut und der blutgefässe und ihre verwendung
Culouscou et al. Biochemical analysis of the epithelin receptor
Garrison et al. Interferon-β inhibits proliferation and progression through S phase of the cell cycle in five glioma cell lines
EP0391911A1 (de) Regelung der expression des gm-csf-gens
EP0822986B1 (de) Antagonisten von humanem interleukin-6, welche zur bindung mit gp 130 unfähig sind und ihre verwendung in der herstellung von pharmazeutische zusammensetzungen
ATE181928T1 (de) Für den rezeptor des granulozytenkolonie stimulierenden faktors kodierende dns
Dore et al. IL‐6 and soluble IL‐6 receptors (sIL‐6R and sgp130) in human pleural effusions: massive IL‐6 production independently of underlying diseases
ATE48142T1 (de) Blutprotein, verfahren zu seiner herstellung, antikoerper gegen dieses protein und dieses protein oder diese antikoerper enthaltende pharmazeutische zubereitungen.
KR20000067914A (ko) 고친화성 인터루킨-4 뮤테인
Feldman et al. Sodium azide enhancement of interleukin-2 production

Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time