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DE69029415D1 - Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden - Google Patents

Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden

Info

Publication number
DE69029415D1
DE69029415D1 DE69029415T DE69029415T DE69029415D1 DE 69029415 D1 DE69029415 D1 DE 69029415D1 DE 69029415 T DE69029415 T DE 69029415T DE 69029415 T DE69029415 T DE 69029415T DE 69029415 D1 DE69029415 D1 DE 69029415D1
Authority
DE
Germany
Prior art keywords
bone marrow
growth factors
factors identified
regenerating bone
osteogenic growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029415T
Other languages
English (en)
Other versions
DE69029415T2 (de
Inventor
Gideon A Rodan
Mohinder K Sardana
John W Jacobs
Dan Gazit
Itai A Bab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of DE69029415D1 publication Critical patent/DE69029415D1/de
Application granted granted Critical
Publication of DE69029415T2 publication Critical patent/DE69029415T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69029415T 1989-02-23 1990-02-21 Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden Expired - Fee Related DE69029415T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31460289A 1989-02-23 1989-02-23

Publications (2)

Publication Number Publication Date
DE69029415D1 true DE69029415D1 (de) 1997-01-30
DE69029415T2 DE69029415T2 (de) 1997-04-03

Family

ID=23220610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029415T Expired - Fee Related DE69029415T2 (de) 1989-02-23 1990-02-21 Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden

Country Status (4)

Country Link
EP (1) EP0384731B1 (de)
JP (1) JPH07103156B2 (de)
CA (1) CA2010660A1 (de)
DE (1) DE69029415T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5461034A (en) * 1989-02-23 1995-10-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
ATE163858T1 (de) * 1991-12-26 1998-03-15 Snow Brand Milk Products Co Ltd Die knochen stärkender faktor und lebensmittel und getränke die diesen faktor enthalten
IL101747A0 (en) * 1992-04-30 1992-12-30 Yissum Res Dev Co C-terminal modified osteogenic growth polypeptides
IL104954A (en) * 1993-03-04 2006-08-01 Yissum Res Dev Co Use of osteogenic oligopeptides in the preparation of pharmaceutical compositions for the treatment of bone diseases and some such novel oligopeptides, pharmaceutical compositions containing them and their preparation
IL117426A (en) 1996-03-10 2005-09-25 Yissum Res Dev Co Synthetic pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
DE102019207859A1 (de) * 2018-12-21 2020-06-25 Gelita Ag Synthetische und rekombinant hergestellte Kollagenpeptide mit biologischer Wirksamkeit

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455256A (en) * 1981-05-05 1984-06-19 The Regents Of The University Of California Bone morphogenetic protein
US4434094A (en) * 1983-04-12 1984-02-28 Collagen Corporation Partially purified osteogenic factor and process for preparing same from demineralized bone
CA1282725C (en) * 1986-04-18 1991-04-09 Brian A. Naughton Process for replicating bone marrow in vitro and using the same
EP0349048A3 (de) * 1988-06-27 1990-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenische Wachstumsfaktoren, die aus Knochenmark gewonnen werden

Also Published As

Publication number Publication date
CA2010660C (de) 1990-08-23
JPH02282396A (ja) 1990-11-19
CA2010660A1 (en) 1990-08-23
EP0384731A3 (de) 1991-06-26
JPH07103156B2 (ja) 1995-11-08
DE69029415T2 (de) 1997-04-03
EP0384731B1 (de) 1996-12-18
EP0384731A2 (de) 1990-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee