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DE68906248D1 - Antagonisten fuer den platelet-aktivierungsfaktor, phomactine genannt, ihre herstellung und verwendung. - Google Patents

Antagonisten fuer den platelet-aktivierungsfaktor, phomactine genannt, ihre herstellung und verwendung.

Info

Publication number
DE68906248D1
DE68906248D1 DE8989312361T DE68906248T DE68906248D1 DE 68906248 D1 DE68906248 D1 DE 68906248D1 DE 8989312361 T DE8989312361 T DE 8989312361T DE 68906248 T DE68906248 T DE 68906248T DE 68906248 D1 DE68906248 D1 DE 68906248D1
Authority
DE
Germany
Prior art keywords
called
antagonists
phomactine
production
platelet activation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989312361T
Other languages
English (en)
Other versions
DE68906248T2 (de
Inventor
Aiya Sato
Michihiro Sugano
Kouhei Furuya
Takeshi Oshima
Harumitsu Kuwano
Tadashi Hata
Hideyuki Haruyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE68906248D1 publication Critical patent/DE68906248D1/de
Publication of DE68906248T2 publication Critical patent/DE68906248T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8989312361T 1988-11-28 1989-11-28 Antagonisten fuer den platelet-aktivierungsfaktor, phomactine genannt, ihre herstellung und verwendung. Expired - Fee Related DE68906248T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30027888 1988-11-28

Publications (2)

Publication Number Publication Date
DE68906248D1 true DE68906248D1 (de) 1993-06-03
DE68906248T2 DE68906248T2 (de) 1993-08-12

Family

ID=17882866

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989312361T Expired - Fee Related DE68906248T2 (de) 1988-11-28 1989-11-28 Antagonisten fuer den platelet-aktivierungsfaktor, phomactine genannt, ihre herstellung und verwendung.

Country Status (7)

Country Link
US (1) US5151529A (de)
EP (1) EP0371762B1 (de)
KR (1) KR940004128B1 (de)
AT (1) ATE88707T1 (de)
CA (1) CA2003956A1 (de)
DE (1) DE68906248T2 (de)
ES (1) ES2055104T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11510388A (ja) * 1995-07-25 1999-09-14 メルク エンド カンパニー インコーポレーテッド ファルネシル−タンパク質転移酵素の阻害剤
US5663193A (en) * 1995-07-25 1997-09-02 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP4123106B2 (ja) 2003-08-22 2008-07-23 ソニー株式会社 有機ｅｌ素子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6339591A (ja) * 1986-08-04 1988-02-20 Nippon Kayaku Co Ltd 新規生理活性物質ＮＫ−Ａ−１７−ｅ−２３３およびその製造法
JPS63307872A (ja) * 1987-06-09 1988-12-15 Nippon Kayaku Co Ltd 新規生理活性物質ＮＫ−Ａ−１７−ｅ−２３３−４およびその製造法

Also Published As

Publication number Publication date
DE68906248T2 (de) 1993-08-12
US5151529A (en) 1992-09-29
KR940004128B1 (ko) 1994-05-13
CA2003956A1 (en) 1990-05-28
KR900008048A (ko) 1990-06-02
ATE88707T1 (de) 1993-05-15
EP0371762A3 (de) 1991-03-20
ES2055104T3 (es) 1994-08-16
EP0371762A2 (de) 1990-06-06
EP0371762B1 (de) 1993-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee