DE60335216D1 - Adiponektin-rezeptor und dafür kodierendes gen - Google Patents
Adiponektin-rezeptor und dafür kodierendes genInfo
- Publication number
- DE60335216D1 DE60335216D1 DE60335216T DE60335216T DE60335216D1 DE 60335216 D1 DE60335216 D1 DE 60335216D1 DE 60335216 T DE60335216 T DE 60335216T DE 60335216 T DE60335216 T DE 60335216T DE 60335216 D1 DE60335216 D1 DE 60335216D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- adiponectin
- receptor
- adiponektin
- binding ability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 6
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 108010076365 Adiponectin Proteins 0.000 abstract 3
- 102000011690 Adiponectin Human genes 0.000 abstract 3
- 102000003808 Adiponectin Receptors Human genes 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 238000012216 screening Methods 0.000 abstract 2
- 108090000179 Adiponectin Receptors Proteins 0.000 abstract 1
- 101000775469 Homo sapiens Adiponectin Proteins 0.000 abstract 1
- 101000775476 Mus musculus Adiponectin Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heat Treatment Of Sheet Steel (AREA)
- Credit Cards Or The Like (AREA)
- Manipulator (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002383738 | 2002-12-29 | ||
PCT/JP2003/007515 WO2004061108A1 (ja) | 2002-12-29 | 2003-06-12 | アディポネクチン受容体及びそれをコードする遺伝子 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60335216D1 true DE60335216D1 (de) | 2011-01-13 |
Family
ID=32708748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60335216T Expired - Lifetime DE60335216D1 (de) | 2002-12-29 | 2003-06-12 | Adiponektin-rezeptor und dafür kodierendes gen |
Country Status (7)
Country | Link |
---|---|
US (4) | US20040241802A1 (de) |
EP (2) | EP1589106B1 (de) |
JP (1) | JP3955885B2 (de) |
AT (1) | ATE490323T1 (de) |
AU (1) | AU2003242352A1 (de) |
DE (1) | DE60335216D1 (de) |
WO (1) | WO2004061108A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60335216D1 (de) | 2002-12-29 | 2011-01-13 | Nissan Chemical Ind Ltd | Adiponektin-rezeptor und dafür kodierendes gen |
WO2005031345A2 (en) * | 2003-09-27 | 2005-04-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor adipor2 (adipor2) |
WO2005042007A1 (ja) * | 2003-11-04 | 2005-05-12 | Sankyo Company, Limited | 抗腫瘍剤 |
EP1733733A1 (de) * | 2004-03-04 | 2006-12-20 | Takashi Kadowaki | Regler für die adiponectin-rezeptor-expression |
WO2005094866A1 (ja) * | 2004-03-31 | 2005-10-13 | Toudai Tlo, Ltd. | アディポネクチン発現誘導剤およびその利用 |
US7399742B2 (en) * | 2004-07-23 | 2008-07-15 | Depuy Spine, Inc. | Anti-osteolytic therapy involving adiponectin |
US20060069024A1 (en) | 2004-09-27 | 2006-03-30 | Purdue Research Foundation | Plant PR-5 proteins as mammalian therapeutic agents |
US7749956B2 (en) | 2005-01-07 | 2010-07-06 | Xencor, Inc. | Method of treatment using adiponectin variants |
EP1833845A2 (de) * | 2005-01-07 | 2007-09-19 | Xencor | Adiponectinvarianten |
US7592423B2 (en) * | 2005-01-07 | 2009-09-22 | Xencor, Inc. | Globular adiponectin variants |
US7678886B2 (en) * | 2005-01-07 | 2010-03-16 | Xencor, Inc. | Pharmaceutical compositions of adiponectin variants and methods of storage |
US20070054359A1 (en) * | 2005-07-11 | 2007-03-08 | Jonathan Zalevsky | Rational Chemical Modification of Adiponectin Variants |
US8093017B2 (en) | 2005-12-07 | 2012-01-10 | Siemens Heathcare Diagnostics Inc. | Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics |
WO2007125324A1 (en) * | 2006-04-26 | 2007-11-08 | Astrazeneca Ab | Method of screening for an antagonist of adiponectin receptor 2 and uses thereof |
JP2008109925A (ja) * | 2006-10-04 | 2008-05-15 | Japan Science & Technology Agency | アディポネクチン受容体遺伝子欠損非ヒト動物及びその用途 |
US8809001B2 (en) * | 2007-09-24 | 2014-08-19 | University Of Florida Research Foundation, Inc. | High throughput assays for inhibitors and activators of PAQR receptors |
WO2009070350A1 (en) | 2007-11-30 | 2009-06-04 | Siemens Healthcare Diagnostics Inc. | Adiponectin receptor fragments and methods of use |
EP3444611A1 (de) | 2009-04-23 | 2019-02-20 | Siemens Healthcare Diagnostics Inc. | Monomere und dimere formen von adiponectin-rezeptor-fragmenten sowie und verfahren zur verwendung davon |
US20110104666A1 (en) * | 2009-11-02 | 2011-05-05 | Toshiya Matsubara | Insulin resistance marker |
WO2011115103A1 (ja) * | 2010-03-16 | 2011-09-22 | 国立大学法人 東京大学 | アディポネクチン受容体1に対するアゴニスト候補化合物のスクリーニング方法 |
JP5048100B2 (ja) | 2010-04-28 | 2012-10-17 | シャープ株式会社 | アディポネクチンに対する結合性を有するペプチド、ならびに該ペプチドを用いた分析方法および分析装置 |
US8889633B2 (en) | 2013-03-15 | 2014-11-18 | Mead Johnson Nutrition Company | Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof |
US9138455B2 (en) | 2013-03-15 | 2015-09-22 | Mead Johnson Nutrition Company | Activating adiponectin by casein hydrolysate |
US9345727B2 (en) | 2013-03-15 | 2016-05-24 | Mead Johnson Nutrition Company | Nutritional compositions containing a peptide component and uses thereof |
US9345741B2 (en) | 2013-03-15 | 2016-05-24 | Mead Johnson Nutrition Company | Nutritional composition containing a peptide component with adiponectin simulating properties and uses thereof |
US9352020B2 (en) | 2013-03-15 | 2016-05-31 | Mead Johnson Nutrition Company | Reducing proinflammatory response |
US9289461B2 (en) | 2013-03-15 | 2016-03-22 | Mead Johnson Nutrition Company | Reducing the risk of autoimmune disease |
WO2018223119A1 (en) * | 2017-06-02 | 2018-12-06 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Engineered cells, and methods of using the same |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
WO1993002227A1 (en) | 1991-07-15 | 1993-02-04 | Eco-Tec Limited | Process and apparatus for treating fluoride containing acid solutions |
JPH07509137A (ja) | 1992-07-24 | 1995-10-12 | セル ジェネシス,インク. | 異種抗体の生産 |
KR100654645B1 (ko) | 1995-04-27 | 2007-04-04 | 아브게닉스, 인크. | 면역화된 제노마우스 유래의 인간 항체 |
WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
US20040067490A1 (en) * | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
EP1074617A3 (de) * | 1999-07-29 | 2004-04-21 | Research Association for Biotechnology | Primers für Synthese von ganzen-Länge cDNS und deren Anwendung |
JP2002191363A (ja) * | 1999-07-29 | 2002-07-09 | Herikkusu Kenkyusho:Kk | 全長cDNA合成用プライマー、およびその用途 |
JP2003527089A (ja) * | 1999-08-17 | 2003-09-16 | インサイト・ゲノミックス・インコーポレイテッド | 膜関連タンパク質 |
AU2001234944A1 (en) * | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
AU2001274888A1 (en) * | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
DE60335216D1 (de) | 2002-12-29 | 2011-01-13 | Nissan Chemical Ind Ltd | Adiponektin-rezeptor und dafür kodierendes gen |
WO2004087874A2 (en) * | 2003-03-28 | 2004-10-14 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
US7435808B2 (en) * | 2003-06-25 | 2008-10-14 | Bristol-Myers Squibb Company | Polynucleotides encoding novel adiponectin receptor variant, AdipoR2v2 |
-
2003
- 2003-06-12 DE DE60335216T patent/DE60335216D1/de not_active Expired - Lifetime
- 2003-06-12 JP JP2004564466A patent/JP3955885B2/ja not_active Expired - Fee Related
- 2003-06-12 WO PCT/JP2003/007515 patent/WO2004061108A1/ja active Application Filing
- 2003-06-12 AT AT03733398T patent/ATE490323T1/de not_active IP Right Cessation
- 2003-06-12 AU AU2003242352A patent/AU2003242352A1/en not_active Abandoned
- 2003-06-12 EP EP03733398A patent/EP1589106B1/de not_active Expired - Lifetime
- 2003-06-12 EP EP09013545.0A patent/EP2141235B1/de not_active Expired - Lifetime
-
2004
- 2004-03-11 US US10/799,943 patent/US20040241802A1/en not_active Abandoned
-
2006
- 2006-11-13 US US11/598,474 patent/US7501490B2/en not_active Expired - Fee Related
-
2009
- 2009-01-29 US US12/322,111 patent/US7977459B2/en not_active Expired - Fee Related
-
2011
- 2011-06-03 US US13/153,017 patent/US8252584B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20120027760A1 (en) | 2012-02-02 |
AU2003242352A1 (en) | 2004-07-29 |
ATE490323T1 (de) | 2010-12-15 |
EP2141235A1 (de) | 2010-01-06 |
US20040241802A1 (en) | 2004-12-02 |
EP2141235B1 (de) | 2014-06-11 |
EP1589106A1 (de) | 2005-10-26 |
US7501490B2 (en) | 2009-03-10 |
AU2003242352A8 (en) | 2004-07-29 |
JP3955885B2 (ja) | 2007-08-08 |
US8252584B2 (en) | 2012-08-28 |
JPWO2004061108A1 (ja) | 2006-05-11 |
US20100062541A1 (en) | 2010-03-11 |
WO2004061108A1 (ja) | 2004-07-22 |
EP1589106A4 (de) | 2006-06-07 |
US20070054314A1 (en) | 2007-03-08 |
EP1589106B1 (de) | 2010-12-01 |
US7977459B2 (en) | 2011-07-12 |
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