DE60314124D1 - 2-(2,6-dichlorphenyl)-diarylimidazole - Google Patents

2-(2,6-dichlorphenyl)-diarylimidazole

Info

Publication number: DE60314124D1
Authority: DE; Germany
Prior art keywords: diarylimidazole; dichloro; phenyl
Prior art date: 2002-04-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60314124T

Other languages

English (en)

Other versions

DE60314124T2 (de

Inventor

Michael Brandt

Georg Fertig

Hans-Willi Krell

Hirschheydt Thomas Dr Von

Edgar Voss

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-18

Filing date

2003-04-16

Publication date

2007-07-12

2003-04-16 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2007-07-12 Publication of DE60314124D1 publication Critical patent/DE60314124D1/de

2008-01-24 Application granted granted Critical

2008-01-24 Publication of DE60314124T2 publication Critical patent/DE60314124T2/de

2023-04-17 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
- C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
- C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Photoreceptors In Electrophotography (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

DE60314124T 2002-04-18 2003-04-16 2-(2,6-dichlorphenyl)-diarylimidazole Expired - Fee Related DE60314124T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP02008228		2002-04-18
EP02008228		2002-04-18
PCT/EP2003/003969 WO2003087026A1 (en)	2002-04-18	2003-04-16	2-(2,6-dichlorophenyl)-diarylimidazoles

Publications (2)

Publication Number	Publication Date
DE60314124D1 true DE60314124D1 (de)	2007-07-12
DE60314124T2 DE60314124T2 (de)	2008-01-24

Family

ID=28799635

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60314124T Expired - Fee Related DE60314124T2 (de)	2002-04-18	2003-04-16	2-(2,6-dichlorphenyl)-diarylimidazole

Country Status (28)

Country	Link
US (2)	US6790852B2 (de)
EP (1)	EP1499577B1 (de)
JP (1)	JP2005522499A (de)
KR (1)	KR100760885B1 (de)
CN (1)	CN1289455C (de)
AR (1)	AR039430A1 (de)
AT (1)	ATE363463T1 (de)
AU (1)	AU2003240452B2 (de)
BR (1)	BR0309355A (de)
CA (1)	CA2482544A1 (de)
DE (1)	DE60314124T2 (de)
DK (1)	DK1499577T3 (de)
ES (1)	ES2286438T3 (de)
GT (1)	GT200300087A (de)
HR (1)	HRP20040954A2 (de)
IL (1)	IL164608A0 (de)
MX (1)	MXPA04010195A (de)
MY (1)	MY135477A (de)
NO (1)	NO20044475L (de)
NZ (1)	NZ535686A (de)
PA (1)	PA8571001A1 (de)
PE (1)	PE20040087A1 (de)
PL (1)	PL372965A1 (de)
PT (1)	PT1499577E (de)
RU (1)	RU2320645C2 (de)
TW (1)	TWI260984B (de)
WO (1)	WO2003087026A1 (de)
ZA (1)	ZA200407817B (de)

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US7144889B2 (en)	2003-10-16	2006-12-05	Hoffman-La Roche Inc.	Triarylimidazoles
US7169781B2 (en)	2003-10-17	2007-01-30	Hoffmann-La Roche Inc.	Imidazole derivatives and their use as pharmaceutical agents
JP5095216B2 (ja) *	2003-11-14	2012-12-12	ローラスセラピューティクスインコーポレーテッド	アリールイミダゾールおよびその抗癌剤としての使用
WO2005082855A1 (ja) *	2004-02-27	2005-09-09	Eisai Co., Ltd.	新規ピリジン誘導体およびピリミジン誘導体（２）
AU2006250809B2 (en)	2005-05-25	2011-05-12	Lorus Therapeutics Inc.	2-indolyl imidazo(4,5-D)phenanthroline derivatives and their use in the treatment of cancer
WO2007016286A1 (en)	2005-07-28	2007-02-08	Janssen Pharmaceutica N.V.	Synthesis of 4/5-pyrimidinylimidazoles via sequential functionalization of 2,4-dichloropyrimidine
KR100950737B1 (ko) *	2005-08-24	2010-03-31	에자이 알앤드디 매니지먼트 가부시키가이샤	신규 피리딘 유도체 및 피리미딘 유도체(3)
CA2645137A1 (en)	2006-03-07	2007-09-13	James F. Blake	Heterobicyclic pyrazole compounds and methods of use
CA2655128A1 (en) *	2006-06-08	2007-12-21	Array Biopharma Inc.	Quinoline compounds and methods of use
JP2010500365A (ja)	2006-08-07	2010-01-07	インサイト・コーポレイション	キナーゼ阻害剤としてのトリアゾロトリアジン
AU2007288793B2 (en) *	2006-08-23	2012-04-19	Eisai R & D Management Co., Ltd.	Salt of phenoxypyridine derivative or crystal thereof and process for producing the same
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CN101641093B (zh)	2006-11-22	2013-05-29	因塞特公司	作为激酶抑制剂的咪唑并三嗪和咪唑并嘧啶
MY148851A (en)	2006-12-14	2013-06-14	Bayer Ip Gmbh	Dihydropyridine derivatives as useful as protein kinase inhibitors
JP2010514692A (ja)	2006-12-20	2010-05-06	バイエルヘルスケアリミティドライアビリティカンパニー	癌の治療に有用なヒドロキシメチルフェニルピラゾリル尿素化合物
JP2009132660A (ja) *	2007-11-30	2009-06-18	Eisai R & D Management Co Ltd	食道癌治療用組成物
JP2009203226A (ja) *	2008-01-31	2009-09-10	Eisai R & D Management Co Ltd	ピリジン誘導体およびピリミジン誘導体を含有するレセプターチロシンキナーゼ阻害剤
EP2248810A4 (de) *	2008-02-18	2011-05-25	Eisai R&D Man Co Ltd	Verfahren zur herstellung eines phenoxypyridin-derivats
WO2009111644A2 (en) *	2008-03-05	2009-09-11	The Regents Of The University Of Michigan	Compositions and methods for diagnosing and treating pancreatic cancer
WO2009143211A2 (en)	2008-05-21	2009-11-26	Incyte Corporation	Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same
BRPI0912927A2 (pt) *	2008-08-29	2019-10-01	Genentech Inc	"método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo"
WO2011162835A1 (en)	2010-02-03	2011-12-29	Incyte Corporation	Imidazo[1,2-b][1,2,4]triazines as c-met inhibitors
ES2573515T3 (es)	2010-06-25	2016-06-08	Eisai R&D Management Co., Ltd.	Agente antitumoral que emplea compuestos con efecto inhibitorio de cinasas combinados
WO2013152252A1 (en)	2012-04-06	2013-10-10	OSI Pharmaceuticals, LLC	Combination anti-cancer therapy
EP2937337A4 (de)	2012-12-21	2016-06-22	Eisai R&D Man Co Ltd	Amorphe form von chinolinderivaten und verfahren zur herstellung davon
WO2014153464A2 (en)	2013-03-20	2014-09-25	Lorus Therapeutics Inc.	2-substituted imidazo[4,5-d]phenanthroline derivatives and their use in the treatment of cancer
US10517861B2 (en)	2013-05-14	2019-12-31	Eisai R&D Management Co., Ltd.	Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
EP3052102B1 (de)	2013-10-04	2019-12-04	Aptose Biosciences Inc.	Zusammensetzungen zur behandlung von krebs
RU2016141385A (ru)	2014-03-24	2018-04-28	Дженентек, Инк.	Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf
ES2926687T3 (es)	2014-08-28	2022-10-27	Eisai R&D Man Co Ltd	Derivado de quinolina muy puro y método para su producción
CA2976325C (en)	2015-02-25	2023-07-04	Eisai R&D Management Co., Ltd.	Method for suppressing bitterness of quinoline derivative
WO2016140717A1 (en)	2015-03-04	2016-09-09	Merck Sharp & Dohme Corp.	Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
WO2016204193A1 (ja)	2015-06-16	2016-12-22	株式会社ＰＲＩＳＭＰｈａｒｍａ	抗がん剤
JP6553726B2 (ja)	2015-08-20	2019-07-31	エーザイ・アール・アンド・ディー・マネジメント株式会社	腫瘍治療剤
JP6581320B2 (ja)	2017-02-08	2019-09-25	エーザイ・アール・アンド・ディー・マネジメント株式会社	腫瘍治療用医薬組成物
JP2020519576A (ja)	2017-05-16	2020-07-02	エーザイ・アール・アンド・ディー・マネジメント株式会社	肝細胞癌の治療
KR20200096914A (ko)	2017-10-30	2020-08-14	압토스 바이오사이언시스 인코포레이티드	암 치료용 아릴 이미다졸
WO2022249192A1 (en) *	2021-05-27	2022-12-01	Ramot At Tel-Aviv University Ltd.	Broad-spectrum metastasis suppressing compounds and therapeutic uses thereof in human tumors

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ATE252094T1 (de)	1994-12-13	2003-11-15	Hoffmann La Roche	Imidazol derivate mit proteinkinase, insbesondere egf-r tyrosinkinase, inhibierender wirkung
WO2001044154A1 (fr)	1999-12-17	2001-06-21	Mitsubishi Chemical Corporation	Derives de dihalopropenyloxybenzene et pesticides contenant ces derniers en tant qu'ingredients actifs

2003
- 2003-04-07 US US10/408,539 patent/US6790852B2/en not_active Expired - Fee Related
- 2003-04-14 GT GT200300087A patent/GT200300087A/es unknown
- 2003-04-15 PA PA20038571001A patent/PA8571001A1/es unknown
- 2003-04-15 PE PE2003000382A patent/PE20040087A1/es not_active Application Discontinuation
- 2003-04-15 TW TW092108660A patent/TWI260984B/zh not_active IP Right Cessation
- 2003-04-16 WO PCT/EP2003/003969 patent/WO2003087026A1/en active IP Right Grant
- 2003-04-16 AU AU2003240452A patent/AU2003240452B2/en not_active Expired - Fee Related
- 2003-04-16 ES ES03729926T patent/ES2286438T3/es not_active Expired - Lifetime
- 2003-04-16 AR ARP030101336A patent/AR039430A1/es not_active Application Discontinuation
- 2003-04-16 DK DK03729926T patent/DK1499577T3/da active
- 2003-04-16 MY MYPI20031436A patent/MY135477A/en unknown
- 2003-04-16 EP EP03729926A patent/EP1499577B1/de not_active Expired - Lifetime
- 2003-04-16 NZ NZ535686A patent/NZ535686A/en unknown
- 2003-04-16 JP JP2003583984A patent/JP2005522499A/ja active Pending
- 2003-04-16 PL PL03372965A patent/PL372965A1/xx unknown
- 2003-04-16 AT AT03729926T patent/ATE363463T1/de not_active IP Right Cessation
- 2003-04-16 KR KR1020047016717A patent/KR100760885B1/ko not_active Expired - Fee Related
- 2003-04-16 PT PT03729926T patent/PT1499577E/pt unknown
- 2003-04-16 CA CA002482544A patent/CA2482544A1/en not_active Abandoned
- 2003-04-16 BR BR0309355-7A patent/BR0309355A/pt not_active IP Right Cessation
- 2003-04-16 RU RU2004133760/04A patent/RU2320645C2/ru not_active IP Right Cessation
- 2003-04-16 DE DE60314124T patent/DE60314124T2/de not_active Expired - Fee Related
- 2003-04-16 HR HR20040954A patent/HRP20040954A2/hr not_active Application Discontinuation
- 2003-04-16 CN CNB038085119A patent/CN1289455C/zh not_active Expired - Fee Related
- 2003-04-16 MX MXPA04010195A patent/MXPA04010195A/es active IP Right Grant
2004
- 2004-05-18 US US10/848,611 patent/US6946471B2/en not_active Expired - Fee Related
- 2004-09-28 ZA ZA200407817A patent/ZA200407817B/xx unknown
- 2004-10-14 IL IL16460804A patent/IL164608A0/xx unknown
- 2004-10-20 NO NO20044475A patent/NO20044475L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK1499577T3 (da)	2007-09-24
HK1078568A1 (en)	2006-03-17
US6790852B2 (en)	2004-09-14
PE20040087A1 (es)	2004-03-06
MY135477A (en)	2008-04-30
CN1289455C (zh)	2006-12-13
RU2320645C2 (ru)	2008-03-27
KR20050005451A (ko)	2005-01-13
NZ535686A (en)	2006-06-30
AR039430A1 (es)	2005-02-16
GT200300087A (es)	2004-01-15
CA2482544A1 (en)	2003-10-23
EP1499577A1 (de)	2005-01-26
ES2286438T3 (es)	2007-12-01
ATE363463T1 (de)	2007-06-15
PL372965A1 (en)	2005-08-08
ZA200407817B (en)	2005-10-04
AU2003240452A1 (en)	2003-10-27
US6946471B2 (en)	2005-09-20
JP2005522499A (ja)	2005-07-28
US20040214874A1 (en)	2004-10-28
KR100760885B1 (ko)	2007-10-04
NO20044475L (no)	2004-11-10
RU2004133760A (ru)	2005-09-10
DE60314124T2 (de)	2008-01-24
MXPA04010195A (es)	2005-02-03
IL164608A0 (en)	2005-12-18
TWI260984B (en)	2006-09-01
TW200306821A (en)	2003-12-01
PA8571001A1 (es)	2003-12-10
CN1646460A (zh)	2005-07-27
US20030199691A1 (en)	2003-10-23
WO2003087026A1 (en)	2003-10-23
EP1499577B1 (de)	2007-05-30
AU2003240452B2 (en)	2008-12-04
PT1499577E (pt)	2007-08-14
HRP20040954A2 (hr)	2005-08-31
BR0309355A (pt)	2005-02-22

Publication	Publication Date	Title
DE60314124D1 (de)	2007-07-12	2-(2,6-dichlorphenyl)-diarylimidazole
CY2014041I1 (el)	2016-07-27	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
NO20041075L (no)	2004-03-15	Ny 1, 2, 4-triazolforbindelse
DK2308855T3 (da)	2013-01-28	2,4-Diaminopyrimidinderivater
DE50300496D1 (de)	2005-06-09	Montagemaschine
DE60305332D1 (de)	2006-06-22	IMIDAZOi1,2-AöPYRIDINE
DE50304148D1 (de)	2006-08-17	Handstichs gemaschine
ITTO20030507A1 (it)	2004-01-02	Premistoppa a tenuta di fango.
ITBO20020284A1 (it)	2003-11-14	Macchina opercolatrice
DE60315471D1 (de)	2007-09-20	2,5-disubstituierte 3-mercaptopentansaure
ITTO20020157A0 (it)	2002-02-25	Macchina depallettizzatrice.
DE10390324D2 (de)	2004-12-23	Geradeaus-Ziehmaschine
ITMI20032170A1 (it)	2004-06-22	Tagliacimosse.
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NO20044405L (no)	2004-10-15	Neurotensinaktive 2,3-diaryl-pyrazolidin derivater
DE50304664D1 (de)	2006-09-28	Handstichs gemaschine
ITMI20021328A1 (it)	2003-12-15	Nuove piperazine 1,4 - disostituite
DE50209339D1 (de)	2007-03-15	Kalander
ES1052590Y (es)	2003-05-01	Quiosco-consigna.
UA6193S (uk)	2002-07-15	Машина тістомісильна «інтенсив-200»
ES1053052Y (es)	2003-06-16	Maquina volteadora.
SE0301847D0 (sv)	2003-06-25	Novel 3,3-Diphenylpropylamines
ITMC20020043A0 (it)	2002-05-23	"macchina per la bricchettatura".
ITMO20020217A1 (it)	2004-02-01	Macchina piegatrice.
ES1051704Y (es)	2003-01-16	Maquina mezcladora-bombeadora de morteros.

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