DE60306865D1 - Detektion von Vancomycin-resistenten Enterococcus-Subspezies - Google Patents
Detektion von Vancomycin-resistenten Enterococcus-SubspeziesInfo
- Publication number
- DE60306865D1 DE60306865D1 DE60306865T DE60306865T DE60306865D1 DE 60306865 D1 DE60306865 D1 DE 60306865D1 DE 60306865 T DE60306865 T DE 60306865T DE 60306865 T DE60306865 T DE 60306865T DE 60306865 D1 DE60306865 D1 DE 60306865D1
- Authority
- DE
- Germany
- Prior art keywords
- vancomycin
- detection
- subspecies
- resistant enterococcus
- resistant enterococci
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000194033 Enterococcus Species 0.000 title 1
- 108010059993 Vancomycin Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title 1
- 229960003165 vancomycin Drugs 0.000 title 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Geophysics And Detection Of Objects (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/254,260 US7074598B2 (en) | 2002-09-25 | 2002-09-25 | Detection of vancomycin-resistant enterococcus spp. |
US254260 | 2002-09-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60306865D1 true DE60306865D1 (de) | 2006-08-31 |
DE60306865T2 DE60306865T2 (de) | 2007-01-25 |
Family
ID=31993312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60306865T Expired - Lifetime DE60306865T2 (de) | 2002-09-25 | 2003-09-20 | Detektion von Vancomycin-resistenten Enterococcus-Subspezies |
Country Status (5)
Country | Link |
---|---|
US (2) | US7074598B2 (de) |
EP (1) | EP1408120B1 (de) |
AT (1) | ATE333521T1 (de) |
DE (1) | DE60306865T2 (de) |
ES (1) | ES2269890T3 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1426447A1 (de) * | 2002-12-06 | 2004-06-09 | Roche Diagnostics GmbH | Verfahren zur Detection des pathogenen gram positiven Bacterien, Bvw. Staphylococcus, Enterococcus and Streptococcus |
US7718361B2 (en) * | 2002-12-06 | 2010-05-18 | Roche Molecular Systems, Inc. | Quantitative test for bacterial pathogens |
US20070059714A1 (en) * | 2005-09-12 | 2007-03-15 | Birgit Strommenger | Detection of presence and antibiotic susceptibility of enterococci |
US8535888B2 (en) * | 2006-12-29 | 2013-09-17 | Mayo Foundation For Medical Education And Research | Compositions and methods for detecting methicillin-resistant S. aureus |
JP5557733B2 (ja) | 2007-04-04 | 2014-07-23 | ネットバイオ・インコーポレーテッド | プラスチック製マイクロ流体分離および検出プラットフォーム |
CA2684570A1 (en) | 2007-04-19 | 2008-10-30 | Molecular Detection Inc. | Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria |
CA2696433A1 (en) * | 2007-08-13 | 2009-03-12 | 3M Innovative Properties Company | Methods for detecting drug-resistant microbes |
WO2010147654A2 (en) | 2009-06-15 | 2010-12-23 | Netbio Inc. | Improved methods for forensic dna quantitation |
WO2011029034A2 (en) * | 2009-09-04 | 2011-03-10 | Intelligent Medical Devices, Inc. | Optimized probes and primers and methods of using same for the detection, screening, isolation and sequencing of vancomycin resistance genes and vancomycin resistant enterococci |
CN102220424B (zh) * | 2011-05-10 | 2013-03-27 | 浙江省质量技术监督检测研究院 | 肠球菌的快速检测方法及检测引物组和检测试剂盒 |
AU2012253271A1 (en) | 2011-05-12 | 2014-01-09 | Netbio, Inc. | Methods and compositions for rapid multiplex amplification of STR loci |
WO2018156664A1 (en) * | 2017-02-21 | 2018-08-30 | Millennium Health, LLC | Methods and systems for microbial genetic test |
CN109706254A (zh) * | 2017-10-20 | 2019-05-03 | 北京爱普益生物科技有限公司 | 检测耐万古霉素基因的引物组合物、探针组合物、试剂盒,及其应用 |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4996143A (en) | 1985-12-23 | 1991-02-26 | Syngene, Inc. | Fluorescent stokes shift probes for polynucleotide hybridization |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
ATE66695T1 (de) | 1986-12-01 | 1991-09-15 | Molecular Biosystems Inc | Verfahren zur erhoehung der empfindlichkeit von nukleinsaeure-hybridisierungstesten. |
JP2791367B2 (ja) | 1988-04-21 | 1998-08-27 | マイクロプローブ・コーポレーション | 核酸抽出方法 |
US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5683896A (en) | 1989-06-01 | 1997-11-04 | Life Technologies, Inc. | Process for controlling contamination of nucleic acid amplification reactions |
US5035996A (en) | 1989-06-01 | 1991-07-30 | Life Technologies, Inc. | Process for controlling contamination of nucleic acid amplification reactions |
JPH0549477A (ja) | 1991-08-05 | 1993-03-02 | Wakunaga Pharmaceut Co Ltd | スタフイロコツカス属細菌類の検出 |
US5565322A (en) | 1991-11-07 | 1996-10-15 | Nanogen, Inc. | Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to donor energy transfer system |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
KR100230909B1 (ko) | 1993-11-29 | 1999-12-01 | 다니엘 엘. 캐시앙 | 광범위의 유기체로부터 핵산 추출 방법 |
US6001564A (en) | 1994-09-12 | 1999-12-14 | Infectio Diagnostic, Inc. | Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories |
US5702895A (en) | 1995-01-19 | 1997-12-30 | Wakunaga Seiyaku Kabushiki Kaisha | Method and kit for detecting methicillin-resistant Staphylococcus aureus |
NZ502323A (en) * | 1996-06-04 | 2001-09-28 | Univ Utah Res Found | Monitoring a fluorescence energy transfer pair during hybridization of first probe labelled with fluorescein to second probe labelled with Cy5 or Cy5.5 |
AU727296B2 (en) | 1996-06-04 | 2000-12-07 | University Of Utah Research Foundation | System and methods for monitoring for DNA amplification by fluorescence |
JP2001521394A (ja) | 1997-04-22 | 2001-11-06 | ババリアン・ノルディック・リサーチ・インスティテュート・アクティーゼルスカブ | 病原性大腸菌株検出用のTaqMan▲上TM▼−PCR |
EP2386629A1 (de) | 1997-10-14 | 2011-11-16 | Darwin Molecular Corporation | Thymidinkinasemutanten und Fusionsproteine mit Thymidinkinase- und Guanylatkinaseaktivität |
GB9803382D0 (en) * | 1998-02-19 | 1998-04-15 | Secr Defence | Detection system |
ES2323562T3 (es) | 1998-03-04 | 2009-07-20 | Biomerieux B.V. | Amplificacion y deteccion de la expresion ebv-barf1 para el diagnostico del carcinoma nasofaringeo. |
US6140054A (en) * | 1998-09-30 | 2000-10-31 | University Of Utah Research Foundation | Multiplex genotyping using fluorescent hybridization probes |
AP1502A (en) | 1998-12-22 | 2005-12-20 | Microscience Ltd | Genes and proteins, and their uses. |
WO2000070096A2 (en) | 1999-01-10 | 2000-11-23 | Exact Laboratories, Inc. | Methods of detecting colorectal disease by conduction an assay to detect a mutation in a bat-26 locus |
US6162605A (en) | 1999-04-12 | 2000-12-19 | Becton Dickinson And Company | Amplification and detection of shiga-like toxin I producing organisms |
US6387621B1 (en) * | 1999-04-27 | 2002-05-14 | University Of Utah Research Foundation | Automated analysis of real-time nucleic acid amplification |
WO2001012803A2 (en) | 1999-08-17 | 2001-02-22 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for restoring antibiotic susceptibility in glycopeptide-resistant enterococcus |
EP2322667A3 (de) | 1999-09-28 | 2011-10-26 | Geneohm Sciences Canada, Inc. | Hochkonserviertes Gen und benutzung dieses Gens zur herstellung Species-, Genus-, Familien- und Gruppen-spezifischer Primer sowie von universellen Nukleinsäureproben zur bestimmung von Mikroorganismen. |
US7297517B2 (en) | 2000-05-29 | 2007-11-20 | Tosoh Corporation | Oligonucleotides and method for detection of meca gene of methicillin-resistant Staphylococcus aureus |
US6849407B2 (en) | 2000-08-31 | 2005-02-01 | Mayo Foundation For Medical Education And Research | Detection of varicella-zoster virus |
AU2002214127B2 (en) | 2000-10-27 | 2007-06-07 | J. Craig Venter Institute, Inc. | Nucleic acids and proteins from streptococcus groups A and B |
US6312929B1 (en) * | 2000-12-22 | 2001-11-06 | Cepheid | Compositions and methods enabling a totally internally controlled amplification reaction |
EP1364063B1 (de) | 2001-01-31 | 2010-04-21 | Mayo Foundation For Medical Education And Research | Nachweis von herpex-simplex-virus |
FR2824074A1 (fr) | 2001-04-26 | 2002-10-31 | Pasteur Institut | Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques |
AUPR774901A0 (en) | 2001-09-19 | 2001-10-11 | Western Sydney Area Health Service | Molecular typing of group b streptococci |
WO2003068918A2 (en) | 2002-02-11 | 2003-08-21 | Auburn University | High-sensitivity real-time polymerase chain reaction for detection of nucleic acids |
US6593093B1 (en) | 2002-02-20 | 2003-07-15 | Mayo Foundation For Medical Education And Research | Detection of group a Streptococcus |
GB0210128D0 (en) | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
-
2002
- 2002-09-25 US US10/254,260 patent/US7074598B2/en not_active Expired - Lifetime
-
2003
- 2003-09-20 AT AT03021347T patent/ATE333521T1/de not_active IP Right Cessation
- 2003-09-20 DE DE60306865T patent/DE60306865T2/de not_active Expired - Lifetime
- 2003-09-20 EP EP03021347A patent/EP1408120B1/de not_active Expired - Lifetime
- 2003-09-20 ES ES03021347T patent/ES2269890T3/es not_active Expired - Lifetime
-
2006
- 2006-07-11 US US11/456,776 patent/US20070031866A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1408120B1 (de) | 2006-07-19 |
EP1408120A2 (de) | 2004-04-14 |
DE60306865T2 (de) | 2007-01-25 |
US20070031866A1 (en) | 2007-02-08 |
US7074598B2 (en) | 2006-07-11 |
EP1408120A3 (de) | 2004-07-14 |
US20040058336A1 (en) | 2004-03-25 |
ES2269890T3 (es) | 2007-04-01 |
ATE333521T1 (de) | 2006-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |