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DE60305053D1 - Pyrimidinderivate als selektive cox-2-inhibitoren - Google Patents

Pyrimidinderivate als selektive cox-2-inhibitoren

Info

Publication number
DE60305053D1
DE60305053D1 DE60305053T DE60305053T DE60305053D1 DE 60305053 D1 DE60305053 D1 DE 60305053D1 DE 60305053 T DE60305053 T DE 60305053T DE 60305053 T DE60305053 T DE 60305053T DE 60305053 D1 DE60305053 D1 DE 60305053D1
Authority
DE
Germany
Prior art keywords
inhibitors
pyrimidine derivatives
selective cox
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60305053T
Other languages
English (en)
Other versions
DE60305053T2 (de
Inventor
Gordon Weingarten
Gianpaolo Bravi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0219305A external-priority patent/GB0219305D0/en
Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE60305053D1 publication Critical patent/DE60305053D1/de
Publication of DE60305053T2 publication Critical patent/DE60305053T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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DE60305053T 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren Expired - Fee Related DE60305053T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219304 2002-08-19
GB0219305 2002-08-19
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
PCT/EP2003/009153 WO2004018452A1 (en) 2002-08-19 2003-08-15 Pyrimidine derivatives as selective cox-2 inhibitors

Publications (2)

Publication Number Publication Date
DE60305053D1 true DE60305053D1 (de) 2006-06-08
DE60305053T2 DE60305053T2 (de) 2006-08-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60305053T Expired - Fee Related DE60305053T2 (de) 2002-08-19 2003-08-15 Pyrimidinderivate als selektive cox-2-inhibitoren

Country Status (8)

Country Link
US (1) US7235560B2 (de)
EP (1) EP1546128B1 (de)
JP (1) JP2006500372A (de)
AT (1) ATE325115T1 (de)
AU (1) AU2003258630A1 (de)
DE (1) DE60305053T2 (de)
ES (1) ES2263058T3 (de)
WO (1) WO2004018452A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1546128B1 (de) 2002-08-19 2006-05-03 Glaxo Group Limited Pyrimidinderivate als selektive cox-2-inhibitoren
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
LT1799196T (lt) 2004-10-08 2016-09-12 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinė kompozicija, apimanti fumaro rūgšties esterį
US7759350B2 (en) * 2005-09-15 2010-07-20 Orchid Research Laboratories Ltd. Pyrimidine carboxamides
EP1940382A2 (de) * 2005-10-07 2008-07-09 Aditech Pharma AB Kombinationstherapie mit fumarsäureestern zur behandlung von autoimmunkrankheiten und/oder entzündlichen erkrankungen
PT2379063E (pt) 2009-01-09 2013-05-03 Forward Pharma As Formulação farmacêutica compreendendo um ou mais ésteres de ácido fumárico numa matriz de erosão
EP2547662A4 (de) * 2010-03-17 2013-10-02 Glaxo Group Ltd Pyrimidinderivate zur verwendung als sphingosin-1-phosphat-1 (s1p1)-rezeptoragonisten
WO2017210545A1 (en) * 2016-06-02 2017-12-07 Cadent Therapeutics, Inc. Potassium channel modulators
UA123810C2 (uk) 2017-01-23 2021-06-02 Цадент Терапеутікс, Інк. Модулятори калієвих каналів
KR20210080446A (ko) 2018-10-22 2021-06-30 카덴트 테라퓨틱스, 인크. 칼륨 채널 조절제의 결정 형태
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US7235560B2 (en) 2007-06-26
ES2263058T3 (es) 2006-12-01
JP2006500372A (ja) 2006-01-05
EP1546128B1 (de) 2006-05-03
DE60305053T2 (de) 2006-08-31
EP1546128A1 (de) 2005-06-29
US20060040967A1 (en) 2006-02-23
ATE325115T1 (de) 2006-06-15

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