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DE60223795D1 - Tetrahydroxylierte estrogen enthaltendes arzneistoffverabreichungssystem zur verwendung in hormonalen kontrazeption - Google Patents

Tetrahydroxylierte estrogen enthaltendes arzneistoffverabreichungssystem zur verwendung in hormonalen kontrazeption

Info

Publication number
DE60223795D1
DE60223795D1 DE60223795T DE60223795T DE60223795D1 DE 60223795 D1 DE60223795 D1 DE 60223795D1 DE 60223795 T DE60223795 T DE 60223795T DE 60223795 T DE60223795 T DE 60223795T DE 60223795 D1 DE60223795 D1 DE 60223795D1
Authority
DE
Germany
Prior art keywords
disposal system
containing drug
hormonal contraception
drug disposal
tetrahydroxylated estrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60223795T
Other languages
English (en)
Other versions
DE60223795T2 (de
Inventor
Christian Franz Holinka
Bennink Herman Jan Coelingh
Evert Johannes Bunschoten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pantarhei Bioscience BV
Original Assignee
Pantarhei Bioscience BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP01201945A external-priority patent/EP1293210B1/de
Application filed by Pantarhei Bioscience BV filed Critical Pantarhei Bioscience BV
Publication of DE60223795D1 publication Critical patent/DE60223795D1/de
Application granted granted Critical
Publication of DE60223795T2 publication Critical patent/DE60223795T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60223795T 2001-05-23 2002-05-23 Tetrahydroxyliertes Östrogen enthaltendes Arzneistoffverabreichungssystem zur Verwendung in der hormonalen Kontrazeption Expired - Lifetime DE60223795T2 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP01201945 2001-05-23
EP01201947 2001-05-23
EP01201946 2001-05-23
EP01201947 2001-05-23
EP01201946 2001-05-23
EP01201945A EP1293210B1 (de) 2001-05-23 2001-05-23 Zubereitungen für die hormonale Kontrazeption
EP01204377 2001-11-15
EP01204377 2001-11-15
EP02075695 2002-02-21
EP02075695 2002-02-21
PCT/NL2002/000331 WO2002094279A1 (en) 2001-05-23 2002-05-23 Drug delivery system comprising a tetrahidroxilated estrogen for use in hormonal contraception

Publications (2)

Publication Number Publication Date
DE60223795D1 true DE60223795D1 (de) 2008-01-10
DE60223795T2 DE60223795T2 (de) 2008-11-27

Family

ID=27513107

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223795T Expired - Lifetime DE60223795T2 (de) 2001-05-23 2002-05-23 Tetrahydroxyliertes Östrogen enthaltendes Arzneistoffverabreichungssystem zur Verwendung in der hormonalen Kontrazeption

Country Status (12)

Country Link
US (1) US7732430B2 (de)
EP (1) EP1390042B1 (de)
CA (1) CA2448278C (de)
CY (2) CY1108093T1 (de)
DE (1) DE60223795T2 (de)
DK (1) DK1390042T3 (de)
ES (1) ES2296943T3 (de)
FR (1) FR21C1033I2 (de)
LU (1) LUC00213I2 (de)
NL (1) NL301115I2 (de)
PT (1) PT1390042E (de)
WO (1) WO2002094279A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60318092T2 (de) 2002-10-23 2008-11-27 Pantarhei Bioscience B.V. Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung
PT1562976E (pt) 2002-11-08 2010-08-12 Pantarhei Bioscience Bv Síntese do estetrol via esteróides derivados da estrona
LT2714712T (lt) 2011-06-01 2016-11-25 Estetra S.P.R.L. Estetrolio tarpinių junginių gamybos būdas
SI2714710T1 (sl) 2011-06-01 2016-08-31 Estetra S.P.R.L. Postopek za proizvodnjo intermediatov estetrola
CA2842175C (en) * 2011-07-19 2019-10-15 Herman Jan Tijmen Coelingh Bennink Tablet containing dehydroepiandrosterone (dhea)
EP2383279A1 (de) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Herstellungsverfahren für Esterol
AU2012293593B2 (en) * 2011-08-11 2017-03-23 Estetra Srl Use of estetrol as emergency contraceptive
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
ES2624667T3 (es) 2013-09-18 2017-07-17 Crystal Pharma, S.A.U. Procedimiento para la preparación de estetrol
ES2655076T3 (es) 2013-12-12 2018-02-16 Donesta Bioscience B.V. Unidad de dosificación sólida de desintegración oral con un componente de estetrol
SMT202100370T1 (it) 2015-06-18 2021-07-12 Estetra Sprl Pastiglia orodispersibile contenente estetrolo
MD3310346T2 (ro) 2015-06-18 2021-06-30 Estetra Sprl Comprimată orodispersabilă ce conține estetrol
MY195019A (en) 2015-06-18 2023-01-03 Estetra Sprl Orodispersible dosage unit containing an estetrol component
PE20180522A1 (es) 2015-06-18 2018-03-14 Mithra Pharmaceuticals S A Unidad de dosificacion orodispersable que contiene un componente estetrol
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
WO2019154899A1 (en) * 2018-02-07 2019-08-15 Estetra Sprl Contraceptive composition with reduced cardiovascular effects
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
MX2024009584A (es) 2022-02-10 2024-08-14 Estetra Srl Metodos anticonceptivos con efectos de sangrado programado.
US12233074B2 (en) 2022-02-10 2025-02-25 Estetra Srl Contraceptive methods with improved pearl index

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US3440320A (en) * 1964-06-18 1969-04-22 Mortimer D Sackler Chelated suppository and method of using same
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
DE2336433A1 (de) 1973-07-13 1975-04-03 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
DE2336434A1 (de) 1973-07-13 1975-04-17 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
DE2426779A1 (de) 1974-05-31 1975-12-18 Schering Ag 1.3-oxygenierte 8 alpha-oestratriene
US4722941A (en) * 1978-06-07 1988-02-02 Kali-Chemie Pharma Gmbh Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof
US4460372A (en) * 1981-02-17 1984-07-17 Alza Corporation Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
US4573996A (en) * 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
US4624665A (en) * 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
US4937238A (en) * 1986-03-04 1990-06-26 The Board Of Regents Of The University Of Nebraska Prevention of mammary carcinoma
US4762717A (en) * 1986-03-21 1988-08-09 The General Hospital Corporation Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive
US5223261A (en) * 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
US5043331A (en) 1989-06-15 1991-08-27 Orion-Yhtyma Oy Treatment of postmenopausal disorders
US5130137A (en) * 1989-08-09 1992-07-14 The General Hospital Corporation Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use in treating benign ovarian secretory disorders
JPH04235171A (ja) 1990-07-26 1992-08-24 Sumitomo Chem Co Ltd スルホヒドロキサム酸誘導体、その製造法およびそれを有効成分とする除草剤
US5063507A (en) * 1990-09-14 1991-11-05 Plains Cotton Cooperative Association Goods database employing electronic title or documentary-type title
US5211952A (en) 1991-04-12 1993-05-18 University Of Southern California Contraceptive methods and formulations for use therein
US5340586A (en) * 1991-04-12 1994-08-23 University Of Southern California Methods and formulations for use in treating oophorectomized women
US5340585A (en) 1991-04-12 1994-08-23 University Of Southern California Method and formulations for use in treating benign gynecological disorders
US5468736A (en) * 1993-02-25 1995-11-21 The Medical College Of Hampton Road Hormone replacement therapy
US5895783A (en) 1993-07-16 1999-04-20 Schering Aktiengesellschaft Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
NL9301562A (nl) * 1993-09-09 1995-04-03 Saturnus Ag Preparaat voor substitutietherapie.
DE4344405C2 (de) 1993-12-24 1995-12-07 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
AU2103495A (en) 1994-08-04 1996-03-04 Biex, Inc. Method for prediction of premature delivery using estetrol (e4) as an indicator
DE4429374C1 (de) * 1994-08-12 1996-02-01 Jenapharm Gmbh Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente
DK0994718T3 (da) 1997-06-20 2005-12-19 Akzo Nobel Nv Gonadotropin releasing hormon-antagonist
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
US6214815B1 (en) * 1998-12-23 2001-04-10 Ortho-Mcneil Pharmaceuticals, Inc. Triphasic oral contraceptive
DE19917930A1 (de) 1999-04-15 2000-10-19 Schering Ag Ent-Steroide als selektiv wirksame Estrogene
AU4543200A (en) 1999-04-16 2000-11-02 Dittgen, Michael Pharmaceutical or cosmetic compositions for the local, intradermal application of hormones
US7273932B1 (en) 1999-05-28 2007-09-25 The University Of Cincinnati Antisense oligonucleotides for fertility and menstrual cycle regulation and for chemopreventive and chemotherapeutic use
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
WO2001085154A2 (en) 2000-05-12 2001-11-15 Oregon Health Sciences University Method of treating immune pathologies with low dose estrogen
US6936599B2 (en) * 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
EP1260225A1 (de) 2001-05-18 2002-11-27 Pantarhei Bioscience B.V. Pharmazeutische Zusammensetzung für die Hormonersatztherapie
US8026228B2 (en) * 2001-11-15 2011-09-27 Pantarhei Bioscience B.V. Estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy

Also Published As

Publication number Publication date
EP1390042A1 (de) 2004-02-25
LUC00213I2 (de) 2021-10-29
FR21C1033I1 (fr) 2021-10-15
US7732430B2 (en) 2010-06-08
DK1390042T3 (da) 2008-03-31
CY2021020I2 (el) 2021-12-31
CA2448278A1 (en) 2002-11-28
DE60223795T2 (de) 2008-11-27
FR21C1033I2 (fr) 2022-04-22
NL301115I1 (de) 2021-07-14
CY2021020I1 (el) 2021-12-31
EP1390042B1 (de) 2007-11-28
PT1390042E (pt) 2008-03-10
WO2002094279A1 (en) 2002-11-28
CY1108093T1 (el) 2014-02-12
NL301115I2 (nl) 2021-10-25
ES2296943T3 (es) 2008-05-01
CA2448278C (en) 2010-06-08
US20040198710A1 (en) 2004-10-07
LUC00213I1 (de) 2021-07-08

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Legal Events

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