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DE60130394D1 - Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen - Google Patents

Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen

Info

Publication number
DE60130394D1
DE60130394D1 DE60130394T DE60130394T DE60130394D1 DE 60130394 D1 DE60130394 D1 DE 60130394D1 DE 60130394 T DE60130394 T DE 60130394T DE 60130394 T DE60130394 T DE 60130394T DE 60130394 D1 DE60130394 D1 DE 60130394D1
Authority
DE
Germany
Prior art keywords
biosynthesis
genes related
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60130394T
Other languages
English (en)
Other versions
DE60130394T2 (de
Inventor
Hiroji Yoshikawa
Yuki Abe
Chiho Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of DE60130394D1 publication Critical patent/DE60130394D1/de
Application granted granted Critical
Publication of DE60130394T2 publication Critical patent/DE60130394T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/385—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Penicillium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60130394T 2000-04-18 2001-04-18 Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen Expired - Lifetime DE60130394T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000116591 2000-04-18
JP2000116591 2000-04-18
JP2000117458 2000-04-19
JP2000117458 2000-04-19

Publications (2)

Publication Number Publication Date
DE60130394D1 true DE60130394D1 (de) 2007-10-25
DE60130394T2 DE60130394T2 (de) 2008-06-19

Family

ID=26590305

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60130394T Expired - Lifetime DE60130394T2 (de) 2000-04-18 2001-04-18 Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen

Country Status (23)

Country Link
US (3) US7056710B2 (de)
EP (1) EP1149919B1 (de)
KR (1) KR100632174B1 (de)
CN (1) CN1325959B (de)
AR (1) AR034550A1 (de)
AT (1) ATE373101T1 (de)
AU (1) AU783319B2 (de)
BR (1) BR0101518A (de)
CA (1) CA2342397C (de)
CY (1) CY1106985T1 (de)
CZ (1) CZ20011367A3 (de)
DE (1) DE60130394T2 (de)
DK (1) DK1149919T3 (de)
ES (1) ES2293966T3 (de)
HU (1) HUP0101569A3 (de)
IL (1) IL142619A (de)
MX (1) MXPA01003913A (de)
NO (1) NO328653B1 (de)
NZ (1) NZ511166A (de)
PL (1) PL202457B1 (de)
PT (1) PT1149919E (de)
RU (1) RU2236463C2 (de)
TW (1) TWI312807B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009540811A (ja) * 2006-06-22 2009-11-26 ディーエスエム アイピー アセッツ ビー．ブイ． プラバスタチンの産生
CN102171328A (zh) * 2008-09-24 2011-08-31 帝斯曼知识产权资产管理有限公司 经改进的斯达汀生产
WO2010069914A1 (en) * 2008-12-19 2010-06-24 Dsm Ip Assets B.V. Statin transcription regulators
WO2015161856A1 (en) * 2014-04-23 2015-10-29 Danmarks Tekniske Universitet Statin resistance and export
CN115851654B (zh) * 2022-11-09 2025-02-07 江西省农业科学院植物保护研究所 一种芦笋茎枯病菌聚酮体合成酶及其编码基因和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS572240A (en) 1980-06-06 1982-01-07 Sankyo Co Ltd Ml-236b derivative
US5179013A (en) * 1987-02-02 1993-01-12 Sankyo Company, Limited Cytochrome P-450 enzymes
JPH09504436A (ja) 1993-11-02 1997-05-06 メルク エンド カンパニー インコーポレーテッド トリオールポリケチドシンターゼをコードするｄｎａ
US5830695A (en) * 1995-11-29 1998-11-03 Sankto Company, Limited Actinomycete promoter
KR100186758B1 (ko) * 1996-08-09 1999-04-01 영진약품공업 주식회사 프라바스타틴(pravastatin)전구체의제조방법
US6391583B1 (en) 1998-12-18 2002-05-21 Wisconsin Alumni Research Foundation Method of producing antihypercholesterolemic agents
AU6475800A (en) 1999-08-11 2001-03-13 Sankyo Company Limited Ml-236b biosynthesis-associated dna
FR2801648B1 (fr) * 1999-11-30 2002-06-21 Commissariat Energie Atomique Injecteur a vapeur haute pression comportant un drain axial

Also Published As

Publication number Publication date
CN1325959B (zh) 2010-05-05
EP1149919B1 (de) 2007-09-12
US20050214909A1 (en) 2005-09-29
PT1149919E (pt) 2007-12-17
CZ20011367A3 (cs) 2001-12-12
EP1149919A2 (de) 2001-10-31
DK1149919T3 (da) 2007-12-03
AU3709201A (en) 2001-10-25
PL202457B1 (pl) 2009-06-30
KR20010098713A (ko) 2001-11-08
NO20011890L (no) 2001-10-19
HK1037683A1 (en) 2002-02-15
HUP0101569A3 (en) 2005-01-28
NO328653B1 (no) 2010-04-19
RU2236463C2 (ru) 2004-09-20
BR0101518A (pt) 2001-11-13
PL347118A1 (en) 2001-10-22
NZ511166A (en) 2002-11-26
AR034550A1 (es) 2004-03-03
TWI312807B (en) 2009-08-01
CA2342397A1 (en) 2001-10-18
US20030078395A1 (en) 2003-04-24
DE60130394T2 (de) 2008-06-19
EP1149919A3 (de) 2002-02-06
HUP0101569A2 (hu) 2002-05-29
CN1325959A (zh) 2001-12-12
NO20011890D0 (no) 2001-04-17
ATE373101T1 (de) 2007-09-15
US7056710B2 (en) 2006-06-06
MXPA01003913A (es) 2003-08-20
AU783319B2 (en) 2005-10-13
US20070111293A1 (en) 2007-05-17
CY1106985T1 (el) 2012-09-26
KR100632174B1 (ko) 2006-10-11
CA2342397C (en) 2011-08-23
ES2293966T3 (es) 2008-04-01
IL142619A (en) 2008-03-20
HU0101569D0 (en) 2001-06-28

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