[go: up one dir, main page]

DE60100873D1 - Eine kristallmodifikation von Celecoxib - Google Patents

Eine kristallmodifikation von Celecoxib

Info

Publication number
DE60100873D1
DE60100873D1 DE60100873T DE60100873T DE60100873D1 DE 60100873 D1 DE60100873 D1 DE 60100873D1 DE 60100873 T DE60100873 T DE 60100873T DE 60100873 T DE60100873 T DE 60100873T DE 60100873 D1 DE60100873 D1 DE 60100873D1
Authority
DE
Germany
Prior art keywords
celecoxib
crystal modification
ylübenzenesulfo
namide
pyrazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60100873T
Other languages
English (en)
Other versions
DE60100873T2 (de
Inventor
Halit Guenduez
Mehmet Bahar
Mehmet Goektepe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fako Ilaclari AS
Original Assignee
Fako Ilaclari AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fako Ilaclari AS filed Critical Fako Ilaclari AS
Publication of DE60100873D1 publication Critical patent/DE60100873D1/de
Application granted granted Critical
Publication of DE60100873T2 publication Critical patent/DE60100873T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE60100873T 2000-06-26 2001-03-15 Eine kristallmodifikation von Celecoxib Expired - Lifetime DE60100873T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR200001872 2000-06-26
TR2000/01872A TR200001872A3 (tr) 2000-06-26 2000-06-26 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine iliskin yöntem.

Publications (2)

Publication Number Publication Date
DE60100873D1 true DE60100873D1 (de) 2003-11-06
DE60100873T2 DE60100873T2 (de) 2004-07-22

Family

ID=21622570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60100873T Expired - Lifetime DE60100873T2 (de) 2000-06-26 2001-03-15 Eine kristallmodifikation von Celecoxib

Country Status (13)

Country Link
US (1) US6391906B2 (de)
EP (1) EP1167355B1 (de)
AT (1) ATE251142T1 (de)
AU (1) AU2001276808A1 (de)
CA (1) CA2350956C (de)
DE (1) DE60100873T2 (de)
EA (1) EA004470B1 (de)
ES (1) ES2206360T3 (de)
HK (1) HK1045155B (de)
IL (1) IL153615A0 (de)
PT (1) PT1167355E (de)
TR (1) TR200001872A3 (de)
WO (1) WO2002000627A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74539C2 (en) * 1999-12-08 2006-01-16 Pharmacia Corp Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)
DE10135027A1 (de) * 2001-07-18 2003-02-06 Solvay Pharm Gmbh Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen
WO2003024400A2 (en) 2001-09-18 2003-03-27 Onconova Therapeutics, Inc. Process for the preparation of 1,5-diarylpyrazoles
US6906196B2 (en) 2001-09-18 2005-06-14 Onconova Therapeutics, Inc. Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles
US7790905B2 (en) 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
WO2004061433A1 (en) * 2002-12-30 2004-07-22 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
JP4906233B2 (ja) 2002-03-01 2012-03-28 ユニバーシティー オブ サウス フロリダ 少なくとも１種の有効薬剤成分を含有する多構成要素固相
WO2003091221A1 (en) * 2002-04-25 2003-11-06 Generics [Uk] Limited Celecoxib forms
AU2002251329A1 (en) * 2002-04-25 2003-11-10 Generics (Uk) Limited Novel crystalline forms of celecoxib and other compounds
CN100348586C (zh) * 2002-05-24 2007-11-14 法玛西雅公司 二芳基吡唑的合成方法
CN100360117C (zh) 2002-06-21 2008-01-09 转化医药公司 具有提高的溶出度的药物组合物
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
KR100820511B1 (ko) * 2004-04-01 2008-04-11 파마시아 앤드 업존 캄파니 엘엘씨 결정성 피라졸 유도체
WO2006024930A1 (en) * 2004-09-01 2006-03-09 Pharmacia & Upjohn Company Llc Novel co-crystals between polyethylene glycols and 5-phenylpyrazolyl-1-benzenesulfonamides
EP1846566B1 (de) * 2004-10-28 2013-04-03 DSM IP Assets B.V. Stabile nadelförmige natamycinkristalle
JP2008528568A (ja) * 2005-01-31 2008-07-31 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Ｉｖ型結晶のセレコキシブ
BRPI0810590A2 (pt) * 2007-05-25 2014-10-21 Exxonmobil Upstream Res Co Método in situ de produzir fluidos de hidrocarboneto de uma formação rochosa rica em matéria orgânica
WO2011055233A2 (en) 2009-11-03 2011-05-12 Actavis Group Ptc Ehf Improved process for preparing celecoxib polymorph
US20110213159A1 (en) * 2010-03-01 2011-09-01 Vamsee Krishna Muppidi Process for preparation of celecoxib crystalline form
CN103524416B (zh) * 2013-10-29 2016-08-17 湖北华世通生物医药科技有限公司 一种塞来昔布新晶型a及其制备方法
CN103539739B (zh) * 2013-10-30 2016-02-10 中美华世通生物医药科技（武汉）有限公司 一种塞来昔布新晶型b及其制备方法
CN103508958A (zh) * 2013-10-30 2014-01-15 中美华世通生物医药科技（武汉）有限公司 一种塞来昔布新晶型c及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604260A (en) 1992-12-11 1997-02-18 Merck Frosst Canada Inc. 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
CA2276946A1 (en) * 1993-11-30 1995-06-08 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides and pharmaceutical compositions containing the same
BR9609043A (pt) * 1995-05-25 1999-02-23 Searle & Co Método de preparar 3 haloalqui 1h pirazois
WO2000042021A1 (en) * 1999-01-14 2000-07-20 Merck Frosst Canada & Co. Synthesis of 4-[(5-substituted or unsubstituted phenyl) -3-substituted -1h-pyrazol -1-yl] benzenesulfonamides
UA74539C2 (en) * 1999-12-08 2006-01-16 Pharmacia Corp Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)

Also Published As

Publication number Publication date
IL153615A0 (en) 2003-07-06
ES2206360T3 (es) 2004-05-16
TR200001872A2 (tr) 2002-01-21
EA200300067A1 (ru) 2003-06-26
EP1167355A1 (de) 2002-01-02
US20020016351A1 (en) 2002-02-07
TR200001872A3 (tr) 2002-01-21
PT1167355E (pt) 2004-02-27
CA2350956A1 (en) 2001-12-26
HK1045155B (zh) 2004-05-28
US6391906B2 (en) 2002-05-21
EP1167355B1 (de) 2003-10-01
HK1045155A1 (en) 2002-11-15
CA2350956C (en) 2005-08-23
WO2002000627A1 (en) 2002-01-03
DE60100873T2 (de) 2004-07-22
ATE251142T1 (de) 2003-10-15
EA004470B1 (ru) 2004-04-29
AU2001276808A1 (en) 2002-01-08

Similar Documents

Publication Publication Date Title
ATE251142T1 (de) Eine kristallmodifikation von celecoxib
DK0931788T3 (da) Metalloproteasehæmmere
ECSP055594A (es) Nuevos derivados de 2-piridiletilbenzamida
ATE308536T1 (de) 4-alkylsubstituierte thienyloxy-pyrididne als herbizide
DK1218372T3 (da) Nye heterocykliske forbindelser, der er anvendelige som reversible inhibitorer af cysteinproteaser
SE0100902D0 (sv) Compounds
FI904327A0 (fi) N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
ATE332130T1 (de) Fab-i-hemmer
NO20042936L (no) Nye krystallinske former av meloksikam og fremgangsmater for deres fremstilling og interkonversjon
BR0211652B1 (pt) compostos de piridona e processo para produÇço de composto de piridina.
DE60219643D1 (de) Heterozyklische carboxamide und ihre verwendung als fungizide
AR008287A1 (es) Composicion herbicida que comprende compuestos de pirazol sustituidos y metodo de aplicacion de los mismos
MXPA04004806A (es) Derivado de n-heteroarilnicotinamida.
MA26299A1 (fr) Procede pour la surveillance et le controle des thysanopteres
BR0009453B1 (pt) processo para a preparação de um composto.
TR200402776T4 (tr) Nöraminik asit bileşiğinin hidratları ve bunların kristal biçimleri.
ATE348800T1 (de) 4'-methansulfonylbiphenylderivate als hochselektive cyclooxygenase-2-inhibitoren
DE60103129D1 (de) Benzofurancarboxamide und deren therapeutische verwendung
DK1637141T3 (da) Stabiliseret proteasesammensætning omfattende en serinprotease, morpholinderivater og reversible inhibitorer af serinproteasen
MXPA03012073A (es) Amidoderivados heterociclicos.
EA200100601A1 (ru) Производные 3-(гетероциклил) бензоилпиразолов
BR0211749B1 (pt) processo para a preparação de derivados de 4-(imidazol-1- il)benzenossulfonamida
DK1499312T3 (da) Anvendelse af hydroxypyridonderivater til sårheling
SE0403003D0 (sv) Chemical compound 1
IS6864A (is) Efnaskiptastjórnuð gerjunaraðferð fyrir framleiðslu á karbamóýltóbramýsíni

Legal Events

Date Code Title Description
8364 No opposition during term of opposition