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DE60027695D1 - Verfahren zur herstellung von fibrinogen und fibronectin sowie proteinzusammesetzungen, welche damit herstellbar sind - Google Patents

Verfahren zur herstellung von fibrinogen und fibronectin sowie proteinzusammesetzungen, welche damit herstellbar sind

Info

Publication number
DE60027695D1
DE60027695D1 DE60027695T DE60027695T DE60027695D1 DE 60027695 D1 DE60027695 D1 DE 60027695D1 DE 60027695 T DE60027695 T DE 60027695T DE 60027695 T DE60027695 T DE 60027695T DE 60027695 D1 DE60027695 D1 DE 60027695D1
Authority
DE
Germany
Prior art keywords
fibronectin
fibrinogen
protein compositions
manufactured
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027695T
Other languages
English (en)
Other versions
DE60027695T2 (de
Inventor
Thomas Seelich
Ralf Broermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter AG
Original Assignee
Baxter AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter AG filed Critical Baxter AG
Application granted granted Critical
Publication of DE60027695D1 publication Critical patent/DE60027695D1/de
Publication of DE60027695T2 publication Critical patent/DE60027695T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60027695T 1999-02-12 2000-02-10 Verfahren zur herstellung von fibrinogen und fibronectin sowie proteinzusammesetzungen, welche damit herstellbar sind Expired - Lifetime DE60027695T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT20699 1999-02-12
AT20699 1999-02-12
PCT/EP2000/001097 WO2000047621A1 (en) 1999-02-12 2000-02-10 A method for producing a preparation based on fibrinogen and fibronectin as well as protein compositions obtainable according to this method
US09/502,029 US6579537B2 (en) 1999-02-12 2000-02-10 Method for producing fibronectin and fibrinogen compositions using a polyalkylene glycol and glycine or β-alanine

Publications (2)

Publication Number Publication Date
DE60027695D1 true DE60027695D1 (de) 2006-06-08
DE60027695T2 DE60027695T2 (de) 2007-04-26

Family

ID=25591856

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027695T Expired - Lifetime DE60027695T2 (de) 1999-02-12 2000-02-10 Verfahren zur herstellung von fibrinogen und fibronectin sowie proteinzusammesetzungen, welche damit herstellbar sind

Country Status (12)

Country Link
US (2) US6579537B2 (de)
EP (1) EP1151007B1 (de)
JP (1) JP2007131638A (de)
AT (1) ATE325133T1 (de)
AU (2) AU774118B2 (de)
CA (1) CA2362513C (de)
DE (1) DE60027695T2 (de)
DK (1) DK1151007T3 (de)
ES (1) ES2263451T3 (de)
PT (1) PT1151007E (de)
SI (1) SI1151007T1 (de)
WO (1) WO2000047621A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4771594B2 (ja) * 1999-02-12 2011-09-14 バクスター アクチェンゲゼルシャフト フィブリノーゲンおよびフィブロネクチンをベースとする製剤を生成するための方法ならびにこの方法により入手可能なタンパク質組成物
US8428685B2 (en) * 2001-09-05 2013-04-23 Given Imaging Ltd. System and method for magnetically maneuvering an in vivo device
US20050221035A1 (en) * 2004-04-01 2005-10-06 Derek Wyatt Method for reducing freeze-thaw voids in uncured adhesives
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
US20070231362A1 (en) * 2006-04-04 2007-10-04 3M Innovative Properties Company Schistose microfibrillated article for cell growth
US20070238167A1 (en) * 2006-04-04 2007-10-11 3M Innovative Properties Company Flat microfibers as matrices for cell growth
EP2142222A2 (de) * 2007-01-18 2010-01-13 Baxter International Inc. Fibringel zur gesteuerten freisetzung von tgf-beta und verwendungen davon
WO2008157733A2 (en) 2007-06-19 2008-12-24 Baxter International Inc. Fibrin gel for controlled release of pdgf and uses thereof
EP2034010A1 (de) 2007-08-30 2009-03-11 Omrix Biopharmaceuticals Ltd. Zusammensetzungen zur Reparatur und/oder Behandlung von verletztem Rückenmarksgewebe
US20100028311A1 (en) * 2008-07-09 2010-02-04 Baxter International Inc. Using of scaffold comprising fibrin for delivery of stem cells
ES2818373T3 (es) * 2009-05-28 2021-04-12 Addbio Ab Películas de proteína de múltiples capas, métodos de preparación y dispositivos de suministro de fármacos e implantes biomédicos que emplean las películas
WO2011085301A1 (en) 2010-01-08 2011-07-14 Baxter International Inc. Biomatrices to attract and retain regenerative and reparative cells
IL207586A0 (en) 2010-08-12 2010-12-30 Omrix Biopharmaceuticals Ltd A fibrin based therapeutic preparation and use thereof
BR112013006384B1 (pt) * 2010-09-20 2021-12-07 Octapharma Ag Processo para purificar fibrinogênio a partir de uma fonte contendo fibrinogênio, produto de fibrinogênio e uso de uma resina de troca aniônica
KR101127127B1 (ko) * 2011-10-27 2012-03-21 주식회사 녹십자 고농도 피브리노겐 용액의 제조 방법 및 이를 이용한 피브린 실란트 제품의 제조방법
US8999376B2 (en) 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
MX351340B (es) 2012-03-13 2017-10-11 Octapharma Ag Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este.
US11071805B2 (en) 2013-04-22 2021-07-27 Sealantium Medical Ltd. Fibrinogen-based tissue adhesive patches
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
AU2016307447A1 (en) 2015-08-07 2018-02-22 Xcede Technologies, Inc. Adhesive compositions and related methods
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
US11471556B2 (en) 2015-10-19 2022-10-18 Sealantium Medical Ltd. Fibrinogen-based tissue adhesive patch
CA3008674C (en) 2015-10-19 2024-02-13 Sealantium Medical Ltd Improved fibrinogen-based tissue adhesive patch
CN105770970A (zh) * 2016-02-29 2016-07-20 苏州市贝克生物科技有限公司 复合多糖止血薄膜及其制备方法
CN105617451A (zh) * 2016-02-29 2016-06-01 苏州市贝克生物科技有限公司 壳聚糖基止血材料及其制备方法
IL247821A0 (en) * 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Adhesive preparations and their use
CN108017710B (zh) * 2018-01-19 2020-02-04 贵州泰邦生物制品有限公司 一种人纤维蛋白原的制备方法
US20220280606A1 (en) * 2019-08-22 2022-09-08 Abdalla S AWIDI Method of preparing a de-fibrinated platelet lysate, and uses of said method
CN117794516A (zh) 2021-08-13 2024-03-29 生物测试股份公司 纤维蛋白原组合物和制备方法
CN118434458A (zh) 2021-12-21 2024-08-02 奥姆里克斯生物药品有限公司 包含纤维蛋白原的制剂及其用途
ES2957484A1 (es) 2022-06-07 2024-01-19 Santxa Res S L U Gel de fibrina y método de obtención del mismo

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
DE3203775A1 (de) 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
AT389815B (de) 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
DK475386D0 (da) * 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
JPH0199565A (ja) * 1987-10-12 1989-04-18 Green Cross Corp:The フィブリン糊調製用キット
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
FR2639958B1 (fr) * 1988-12-06 1992-08-21 Lille Transfusion Sanguine Support biologique pour cultures cellulaires constitue de proteines plasmatiques coagulees par la thrombine, son utilisation pour la culture des keratinocytes, leur recuperation et leur transport a des fins d'utilisation therapeutique
US5196185A (en) * 1989-09-11 1993-03-23 Micro-Collagen Pharmaceutics, Ltd. Collagen-based wound dressing and method for applying same
WO1992013495A1 (en) 1991-02-07 1992-08-20 Fibratek, Inc. Fibrinogen based adhesive
JPH04347162A (ja) * 1991-05-23 1992-12-02 Japan Synthetic Rubber Co Ltd 生体組織接着剤
AT402891B (de) 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
AU6653094A (en) 1992-12-16 1994-07-04 Immuno Aktiengesellschaft Process for preparing a virus-safe biological composition
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
US5330974A (en) 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
AT402788B (de) 1993-08-03 1997-08-25 Immuno Ag Virussichere blutgerinnungsfaktor xiii-präparation
HRP940645A2 (en) 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
AT406019B (de) 1995-05-08 2000-01-25 Immuno Ag Verfahren zur herstellung eines arzneimittels enthaltend ein oder mehrere plasmaderivate
DE19617369A1 (de) * 1996-04-30 1997-11-06 Immuno Ag Lagerstabile Fibrinogen-Präparate
AT407117B (de) 1997-09-19 2000-12-27 Immuno Ag Fibrinschwamm
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
JP4771594B2 (ja) * 1999-02-12 2011-09-14 バクスター アクチェンゲゼルシャフト フィブリノーゲンおよびフィブロネクチンをベースとする製剤を生成するための方法ならびにこの方法により入手可能なタンパク質組成物

Also Published As

Publication number Publication date
SI1151007T1 (sl) 2006-10-31
US6579537B2 (en) 2003-06-17
JP2007131638A (ja) 2007-05-31
AU774118B2 (en) 2004-06-17
DE60027695T2 (de) 2007-04-26
ES2263451T3 (es) 2006-12-16
US20020172718A1 (en) 2002-11-21
US20030077270A1 (en) 2003-04-24
US7241603B2 (en) 2007-07-10
DK1151007T3 (da) 2006-09-04
WO2000047621A1 (en) 2000-08-17
AU2804100A (en) 2000-08-29
CA2362513C (en) 2011-04-26
CA2362513A1 (en) 2000-08-17
AU2004201982A1 (en) 2004-06-03
ATE325133T1 (de) 2006-06-15
EP1151007B1 (de) 2006-05-03
EP1151007A1 (de) 2001-11-07
AU2004201982B2 (en) 2007-12-06
PT1151007E (pt) 2006-07-31

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