DE60015791D1 - Verfahren zur herstellung von mikania extrakten enthaltend mikanolide und dihydromikanolide und verwendung in der behandlung proliferativer erkrankungen - Google Patents
Verfahren zur herstellung von mikania extrakten enthaltend mikanolide und dihydromikanolide und verwendung in der behandlung proliferativer erkrankungenInfo
- Publication number
- DE60015791D1 DE60015791D1 DE60015791T DE60015791T DE60015791D1 DE 60015791 D1 DE60015791 D1 DE 60015791D1 DE 60015791 T DE60015791 T DE 60015791T DE 60015791 T DE60015791 T DE 60015791T DE 60015791 D1 DE60015791 D1 DE 60015791D1
- Authority
- DE
- Germany
- Prior art keywords
- proliferative diseases
- mikanolides
- dihydromicanolids
- mikania
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000002062 proliferating effect Effects 0.000 title abstract 2
- 241001473283 Mikania Species 0.000 title 1
- 239000000284 extract Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 2
- UOQXZMNXWXQCJU-XMOWUHPBSA-N Dihydromikanolide Chemical compound C([C@H]1[C@H]2[C@H](C(O1)=O)C)[C@]1(C)O[C@H]1[C@@H]1O[C@@H]1C1=C[C@H]2OC1=O UOQXZMNXWXQCJU-XMOWUHPBSA-N 0.000 abstract 1
- UOQXZMNXWXQCJU-VUUDCVLBSA-N Dihydromikanolide Natural products O=C1[C@@H](C)[C@H]2[C@H]3OC(=O)C([C@H]4O[C@H]4[C@H]4[C@@](C)(O4)C[C@@H]2O1)=C3 UOQXZMNXWXQCJU-VUUDCVLBSA-N 0.000 abstract 1
- JRZGAAFGODYEEA-UHFFFAOYSA-N Mikanolid Natural products C12OC2C(O2)C2(C)CC2OC(=O)C(=C)C2C2OC(=O)C1=C2 JRZGAAFGODYEEA-UHFFFAOYSA-N 0.000 abstract 1
- JRZGAAFGODYEEA-ATNXOXLHSA-N Mikanolide Chemical compound C([C@]1([C@H]([C@@H]2O[C@@H]22)O1)C)[C@@H]1OC(=O)C(=C)[C@H]1[C@@H]1OC(=O)C2=C1 JRZGAAFGODYEEA-ATNXOXLHSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9915126 | 1999-12-01 | ||
| FR9915126A FR2801792B1 (fr) | 1999-12-01 | 1999-12-01 | Un nouveau medicament, le dihydromikanolide, son obtention par extraction de la plante mikania micrantha et son utilisation comme agent anti-proliferatif |
| PCT/FR2000/003337 WO2001039720A2 (fr) | 1999-12-01 | 2000-11-30 | Inhibiteurs des adn polymerases, le mikanolide et le dihydromikanolide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60015791D1 true DE60015791D1 (de) | 2004-12-16 |
| DE60015791T2 DE60015791T2 (de) | 2005-12-08 |
Family
ID=9552757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60015791T Expired - Lifetime DE60015791T2 (de) | 1999-12-01 | 2000-11-30 | Verfahren zur herstellung von mikania extrakten enthaltend mikanolide und dihydromikanolide und verwendung in der behandlung proliferativer erkrankungen |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6767561B2 (de) |
| EP (1) | EP1237562B1 (de) |
| JP (1) | JP2003515546A (de) |
| AT (1) | ATE281841T1 (de) |
| AU (1) | AU2180501A (de) |
| CA (1) | CA2393056A1 (de) |
| DE (1) | DE60015791T2 (de) |
| DK (1) | DK1237562T3 (de) |
| ES (1) | ES2232515T3 (de) |
| FR (1) | FR2801792B1 (de) |
| PT (1) | PT1237562E (de) |
| RU (1) | RU2254136C2 (de) |
| WO (1) | WO2001039720A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7202076B2 (en) * | 2000-10-30 | 2007-04-10 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| FR2819513B1 (fr) * | 2001-01-12 | 2005-06-17 | Sod Conseils Rech Applic | Nouveaux derives du mikanolide, leur preparation et leurs applications therapeutiques |
| TWI293302B (en) * | 2001-01-12 | 2008-02-11 | Sod Conseils Rech Applic | New derivatives of mikanolide, their preparation and their therapeutic uses |
| FR2825278A1 (fr) * | 2001-05-30 | 2002-12-06 | Sod Conseils Rech Applic | Produit comprenant du mikanolide, du dihydromikanolide ou un analogue de ceux-ci en association avec un autre agent anti-cancereux pour une utilisation therapeutique dans le traitement du cancer |
| IL159296A0 (en) | 2001-06-13 | 2004-06-01 | Magnachem Int Lab Inc | Lactone formulations and method of use |
| US8188145B2 (en) | 2002-06-12 | 2012-05-29 | Magnachem International Laboratories, Inc. | Synthetic lactone formulations and method of use |
| AU2003287546A1 (en) | 2002-11-05 | 2004-06-07 | Magnachem International Laboratories, Inc. | Synthetic lactone formulations and method of use |
| AU2005258148B2 (en) * | 2004-06-21 | 2008-03-20 | Aveda Corporation | Solvent based plant extracts |
| FR2949343B1 (fr) * | 2009-09-01 | 2011-10-21 | Oreal | Procede d'obtention d'un extrait vegetal, extrait vegetal obtenu selon le procede et composition cosmetique ou dermatologique contenant l'extrait |
| CN104082351A (zh) * | 2014-06-03 | 2014-10-08 | 北京化工大学 | 以薇甘菊为载体的防蛀剂及其制备方法 |
| CN104054754B (zh) * | 2014-07-01 | 2016-08-31 | 广州中医药大学 | 一种薇甘菊蚊虫驱避剂 |
| CN104322239B (zh) * | 2014-08-29 | 2019-06-21 | 云南省林业科学院 | 一种利用麻竹控制薇甘菊的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07267940A (ja) * | 1994-03-29 | 1995-10-17 | Ajinomoto Co Inc | 新規な１１員環化合物 |
| US5773005A (en) * | 1995-06-09 | 1998-06-30 | Takahashi; Hidehiko | Purified flavonoid and diterpene 5α-reductase inhibitors from thuja orientalis for androgen-related diseases |
-
1999
- 1999-12-01 FR FR9915126A patent/FR2801792B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-30 EP EP00985359A patent/EP1237562B1/de not_active Expired - Lifetime
- 2000-11-30 RU RU2002117303/15A patent/RU2254136C2/ru not_active IP Right Cessation
- 2000-11-30 DK DK00985359T patent/DK1237562T3/da active
- 2000-11-30 AU AU21805/01A patent/AU2180501A/en not_active Abandoned
- 2000-11-30 WO PCT/FR2000/003337 patent/WO2001039720A2/fr active IP Right Grant
- 2000-11-30 DE DE60015791T patent/DE60015791T2/de not_active Expired - Lifetime
- 2000-11-30 AT AT00985359T patent/ATE281841T1/de not_active IP Right Cessation
- 2000-11-30 US US10/148,539 patent/US6767561B2/en not_active Expired - Fee Related
- 2000-11-30 CA CA002393056A patent/CA2393056A1/fr not_active Abandoned
- 2000-11-30 PT PT00985359T patent/PT1237562E/pt unknown
- 2000-11-30 JP JP2001541455A patent/JP2003515546A/ja active Pending
- 2000-11-30 ES ES00985359T patent/ES2232515T3/es not_active Expired - Lifetime
-
2004
- 2004-06-09 US US10/864,230 patent/US7091239B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE281841T1 (de) | 2004-11-15 |
| JP2003515546A (ja) | 2003-05-07 |
| US20030118678A1 (en) | 2003-06-26 |
| RU2002117303A (ru) | 2004-02-27 |
| FR2801792B1 (fr) | 2003-04-18 |
| US6767561B2 (en) | 2004-07-27 |
| PT1237562E (pt) | 2005-03-31 |
| ES2232515T3 (es) | 2005-06-01 |
| WO2001039720A2 (fr) | 2001-06-07 |
| US7091239B2 (en) | 2006-08-15 |
| FR2801792A1 (fr) | 2001-06-08 |
| US20050208155A1 (en) | 2005-09-22 |
| EP1237562B1 (de) | 2004-11-10 |
| AU2180501A (en) | 2001-06-12 |
| RU2254136C2 (ru) | 2005-06-20 |
| CA2393056A1 (fr) | 2001-06-07 |
| EP1237562A2 (de) | 2002-09-11 |
| DE60015791T2 (de) | 2005-12-08 |
| WO2001039720A3 (fr) | 2002-04-04 |
| DK1237562T3 (da) | 2005-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR |